erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Maxillofacial Injuries D008446 1 associated lipids
Dacryocystitis D003607 1 associated lipids
Erythrasma D004894 1 associated lipids
Granuloma, Respiratory Tract D015769 1 associated lipids
Pilonidal Sinus D010864 1 associated lipids
Postoperative Nausea and Vomiting D020250 1 associated lipids
Vagus Nerve Injuries D061223 1 associated lipids
Focal Infection, Dental D005491 1 associated lipids
Sialadenitis D012793 1 associated lipids
Jaw Abnormalities D007569 1 associated lipids
Lymphoma, B-Cell, Marginal Zone D018442 1 associated lipids
Pericarditis, Constrictive D010494 1 associated lipids
Microphthalmos D008850 1 associated lipids
Peritonsillar Abscess D000039 1 associated lipids
Staphylococcal Scalded Skin Syndrome D013206 1 associated lipids
Actinomycosis, Cervicofacial D000197 1 associated lipids
Ophthalmia Neonatorum D009878 1 associated lipids
Peliosis Hepatis D010382 1 associated lipids
Epidural Abscess D020802 1 associated lipids
Skin Diseases, Vascular D017445 1 associated lipids
Angiomatosis D000798 1 associated lipids
Keratoderma, Palmoplantar D007645 1 associated lipids
Syphilis, Cardiovascular D013589 1 associated lipids
Chalazion D017043 1 associated lipids
Parapsoriasis D010267 1 associated lipids
Stomatognathic Diseases D009057 1 associated lipids
Typhus, Epidemic Louse-Borne D014438 1 associated lipids
Myiasis D009198 1 associated lipids
Splenic Infarction D013159 1 associated lipids
Thyroid Crisis D013958 1 associated lipids
Trench Fever D014205 1 associated lipids
Papillon-Lefevre Disease D010214 1 associated lipids
Meningitis, Listeria D008584 1 associated lipids
Digestive System Abnormalities D004065 1 associated lipids
Occupational Injuries D060051 1 associated lipids
Hereditary Sensory and Autonomic Neuropathies D009477 1 associated lipids
Megacolon D008531 1 associated lipids
Syphilis, Cutaneous D013591 1 associated lipids
Pneumonia, Ventilator-Associated D053717 1 associated lipids
Spider Bites D001098 1 associated lipids
Choroiditis D002833 1 associated lipids
Epidermitis, Exudative, of Swine D004818 1 associated lipids
Heart Murmurs D006337 1 associated lipids
Prolapse D011391 1 associated lipids
Compartment Syndromes D003161 1 associated lipids
Fecal Incontinence D005242 1 associated lipids
Rat-Bite Fever D011906 1 associated lipids
Pelvic Infection D034161 1 associated lipids
Hematemesis D006396 1 associated lipids
Carbuncle D002270 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Kataja J et al. Clonal spread of group A streptococcus with the new type of erythromycin resistance. Finnish Study Group for Antimicrobial Resistance. 1998 J. Infect. Dis. pmid:9498465
Wong PW et al. Multiple organ toxicity from addition of erythromycin to long-term lovastatin therapy. 1998 South. Med. J. pmid:9496876
Kondoh K and Hashiba M [Inhibitory effect of macrolide antibiotics on biofilm formation by Pseudomonas aeruginosa]. 1998 Nippon Jibiinkoka Gakkai Kaiho pmid:9493436
Pereda A et al. The loading domain of the erythromycin polyketide synthase is not essential for erythromycin biosynthesis in Saccharopolyspora erythraea. 1998 Microbiology (Reading, Engl.) pmid:9493390
Hoppe JE [Pertussis: current aspects of diagnosis, therapy and prevention]. 1998 Ther Umsch pmid:9492614
Anderson KL et al. Conjugal transfer of transposon Tn1545 into the cellulolytic bacterium Eubacterium cellulosolvens. 1998 Lett. Appl. Microbiol. pmid:9489031
Stout JE et al. Comparative activity of ciprofloxacin, ofloxacin, levofloxacin, and erythromycin against Legionella species by broth microdilution and intracellular susceptibility testing in HL-60 cells. 1998 Diagn. Microbiol. Infect. Dis. pmid:9488830
Kurmanova KB et al. [Efficacy of pefloxacin in the treatment of complicated relapsing erysipelas]. 1997 Antibiot. Khimioter. pmid:9480650
Saito A [Emerging infectious diseases--Legionella pneumophila infections]. 1997 Nippon Naika Gakkai Zasshi pmid:9480307
Cheftel E et al. [Toxic food infection caused by Shigella flexneri in a military unit]. 1997 Sep-Oct Sante pmid:9480034
Gubina M et al. Septicaemia and meningitis with campylobacter fetus subspecies intestinalis. 1976 Infection pmid:947847
Vining LC Antibiotic tolerance in producer organisms. 1979 Adv. Appl. Microbiol. pmid:94753
Volmer DA and Hui JP Study of erythromycin A decomposition products in aqueous solution by solid-phase microextraction/liquid chromatography/tandem mass spectrometry. 1998 Rapid Commun. Mass Spectrom. pmid:9474800
Fazekas T et al. Suppression of erythromycin-induced early afterdepolarizations and torsade de pointes ventricular tachycardia by mexiletine. 1998 Pacing Clin Electrophysiol pmid:9474662
Schuetz EG et al. Human MDR1 and mouse mdr1a P-glycoprotein alter the cellular retention and disposition of erythromycin, but not of retinoic acid or benzo(a)pyrene. 1998 Arch. Biochem. Biophys. pmid:9473310
Mast WE and Burrows WM Erythema chronicum migrans in the United States. 1976 JAMA pmid:947268
Alegre M et al. [Psychosis due to the interaction of erythromycin and bromocriptine in Parkinson disease]. 1997 Neurologia pmid:9471184
Gurevitz SL Erythromycin: drug interactions. 1997 J Dent Hyg pmid:9470569
Adair CD et al. Chlamydia in pregnancy: a randomized trial of azithromycin and erythromycin. 1998 Obstet Gynecol pmid:9469269
Dobson RL Diagnosis and treatment of eczema. 1976 JAMA pmid:946853
Tsuruta S et al. Inhibition of nifedipine metabolism in dogs by erythromycin: difference between the gut wall and the liver. 1997 J. Pharm. Pharmacol. pmid:9466344
Granovsky-Grisaru S et al. Effects of erythromycin on contractility of isolated myometrium from pregnant rats. 1998 Am. J. Obstet. Gynecol. pmid:9465824
Sadovnikova SF and Selina EV [Five years of sumamed on Russian market]. 1997 Antibiot. Khimioter. pmid:9463300
Zurabyan VA et al. [In vitro influence of biologically active factors of microorganisms on antibiotic susceptibility of Yersinia pestis]. 1997 Antibiot. Khimioter. pmid:9463297
Angeles BL et al. A bacterial sensitivity test to determine the effectiveness of minocycline HCI (Minocin), erythromycin (Erythrocin) and ampicillin (Ampicin) on the predominant microorganisms present in a diseased periodontium. 1994 Jun-Aug J Philipp Dent Assoc pmid:9462063
Nalepa P and Micherdzińska K [Severe pneumonia caused by Chlamydia pneumoniae in a patient treated with steroids for bronchial asthma]. 1997 Pol. Merkur. Lekarski pmid:9461730
Rampling A et al. Community-acquired Legionnaires' disease following minimal exposure to a contaminated source. 1997 J. Infect. pmid:9459407
Pfaller MA et al. In vitro activity of cefepime and ceftazidime against 197 nosocomial blood stream isolates of streptococci: a multicenter sample. 1997 Diagn. Microbiol. Infect. Dis. pmid:9458985
Pfaller MA et al. Nosocomial streptococcal blood stream infections in the SCOPE Program: species occurrence and antimicrobial resistance. The SCOPE Hospital Study Group. 1997 Diagn. Microbiol. Infect. Dis. pmid:9458983
Borek AP et al. Evolving clinical problems with Streptococcus pneumoniae: increasing resistance to antimicrobial agents, and failure of traditional optochin identification in Chicago, Illinois, between 1993 and 1996. 1997 Diagn. Microbiol. Infect. Dis. pmid:9458976
Mathis C and Malbert CH Erythromycin gastrokinetic activity is partially vagally mediated. 1998 Am. J. Physiol. pmid:9458776
Yeates RA et al. Pharmacokinetic and pharmacodynamic interaction study between midazolam and the macrolide antibiotics, erythromycin, clarithromycin, and the azalide azithromycin. 1997 Int J Clin Pharmacol Ther pmid:9455717
Shirai R et al. [Analysis of cases allowed to cease erythromycin therapy for diffuse panbronchiolitis--comparative study between patients with cessation of the therapy and patients continuing the therapy]. 1997 Kansenshogaku Zasshi pmid:9455056
Granados MA and French L Antibiotic treatment in preterm PROM. 1998 J Fam Pract pmid:9451358
Cocuzza CE et al. High incidence of erythromycin-resistant Streptococcus pyogenes in Monza (North Italy) in untreated children with symptoms of acute pharyngo-tonsillitis: an epidemiological and molecular study. 1997 Microb. Drug Resist. pmid:9442490
Chen B et al. Ameliorating effect of erythromycin on bleomycin-induced pulmonary fibrosis: role of alveolar macrophage activation and cytokine release. 1997 Respirology pmid:9441129
Fenton LJ and Light IJ Congenital syphilis after maternal treatment with erythromycin. 1976 Obstet Gynecol pmid:943741
Karbowski M et al. Induction of megamitochondria by some chemicals inducing oxidative stress in primary cultured rat hepatocytes. 1997 Biochim. Biophys. Acta pmid:9434138
Folwaczny C et al. [Effects of various prokinetic drugs on gastrointestinal transit times in patients with progressive systemic scleroderma]. 1997 Z Gastroenterol pmid:9432812
Freidank H [Diagnosis and therapy of Chlamydia pneumoniae and trachomatis]. 1997 Internist (Berl) pmid:9432510
Park HJ et al. Effect of erythromycin on gastric emptying in healthy individuals assessed by radio-opaque markers and plasma acetaminophen levels. 1997 J. Gastroenterol. pmid:9430010
Ross EA and Koo LC Improved nutrition after the detection and treatment of occult gastroparesis in nondiabetic dialysis patients. 1998 Am. J. Kidney Dis. pmid:9428453
Rooney G and Robinson A Look out for the hidden STD. 1997 Practitioner pmid:9425710
Passerini de Rossi BN et al. [Selection of Bvg- variants of Bordetella pertussis]. 1997 Apr-Jun Rev. Argent. Microbiol. pmid:9424628
Martins JC et al. Optimal detection of weak nJ(1H- 119Sn) couplings by gradient-enhanced 1D and 2D heteronuclear multiple-quantum correlation spectroscopy. Application to a novel tin derivative of erythromycin A. 1997 J. Magn. Reson. pmid:9424309
Midolo PD et al. Antimicrobial resistance testing of Helicobacter pylori: a comparison of Etest and disk diffusion methods. 1997 Pathology pmid:9423225
Marsden AF et al. Engineering broader specificity into an antibiotic-producing polyketide synthase. 1998 Science pmid:9422686
Ruzin A and Novick RP Glycerol monolaurate inhibits induction of vancomycin resistance in Enterococcus faecalis. 1998 J. Bacteriol. pmid:9422612
Guin JD et al. Antibiotic sensitivity of comedonal Propionibacterium acnes. 1979 Acta Derm. Venereol. pmid:94223
Fischman AJ et al. The role of positron emission tomography in pharmacokinetic analysis. 1997 Drug Metab. Rev. pmid:9421680