erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Abarzúa F et al. | [Streptococcus agalactiae increase in resistance to erythromycin and clindamycin in vaginal-anal colonization in third quarter of pregnancy in one decade of universal screening]. | 2011 | Rev Chilena Infectol | pmid:22052397 |
Hiller NL et al. | Differences in genotype and virulence among four multidrug-resistant Streptococcus pneumoniae isolates belonging to the PMEN1 clone. | 2011 | PLoS ONE | pmid:22205975 |
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Ren GW et al. | Rapid detection of point mutations in domain V of the 23S rRNA gene in erythromycin-resistant Campylobacter isolates by pyrosequencing. | 2011 | Foodborne Pathog. Dis. | pmid:21166562 |
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Sonnevend à et al. | Lack of correlation between the 257C-to-T mutation in the gyrA gene and clinical severity of Campylobacter jejuni infection in a region of high incidence of ciprofloxacin resistance. | 2011 | Scand. J. Infect. Dis. | pmid:21905953 |
Jessick AM et al. | Optimization of analytical methods to improve detection of erythromycin from water and sediment. | 2011 | J Environ Sci Health B | pmid:21877980 |
Lee CY et al. | Identification and treatment of bisphosphonate-associated actinomycotic osteonecrosis of the jaws. | 2011 | Implant Dent | pmid:21881516 |
Torra S et al. | Meal size can be decreased in obese subjects through pharmacological acceleration of gastric emptying (The OBERYTH trial). | 2011 | Int J Obes (Lond) | pmid:20938444 |
Li MJ et al. | High electrochemiluminescence of a new water-soluble iridium(III) complex for determination of antibiotics. | 2011 | Analyst | pmid:20944848 |
Wan G et al. | Cyclic AMP signalling through PKA but not Epac is essential for neurturin-induced biphasic ERK1/2 activation and neurite outgrowths through GFRα2 isoforms. | 2011 | Cell. Signal. | pmid:21723942 |
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Wenzel F et al. | Alterations of serum erythropoietin and thrombopoietin levels in patients undergoing Coronary Artery Bypass Grafting (CABG). | 2011 | Clin. Hemorheol. Microcirc. | pmid:22214710 |
Amarir-Bouhram J et al. | Low efficiency of homology-facilitated illegitimate recombination during conjugation in Escherichia coli. | 2011 | PLoS ONE | pmid:22194937 |
Ng PC | Erythromycin as a prokinetic agent in newborns--useful or doubtful. Commentary on Y. Mansi et al.: Randomized controlled trial of a high dose of oral erythromycin for the treatment of feeding intolerance in preterm infants (Neonatology 2011;100:290-294). | 2011 | Neonatology | pmid:21701224 |
Sarig H et al. | Functional studies of cochleate assemblies of an oligo-acyl-lysyl with lipid mixtures for combating bacterial multidrug resistance. | 2011 | FASEB J. | pmid:21676947 |
Shingate BB et al. | Stereoselective synthesis and antimicrobial activity of steroidal C-20 tertiary alcohols with thiazole/pyridine side chain. | 2011 | Eur J Med Chem | pmid:21664730 |
Buendia J et al. | Preparation of diastereomerically pure dilignol model compounds. | 2011 | Chemistry | pmid:22076640 |
Hoa PT et al. | Antibiotic contamination and occurrence of antibiotic-resistant bacteria in aquatic environments of northern Vietnam. | 2011 | Sci. Total Environ. | pmid:21669325 |
Joao EC et al. | Group B Streptococcus in a cohort of HIV-infected pregnant women: prevalence of colonization, identification and antimicrobial susceptibility profile. | 2011 | Scand. J. Infect. Dis. | pmid:21671824 |
Hernández y Ballinas A et al. | [Comparison of maternal and perinatal outcomes in the conservative treatment preterm premature membrane rupture between the use of erythromycin and clindamycin]. | 2011 | Ginecol Obstet Mex | pmid:21966834 |
Gupta R et al. | A 14-year-old with rectal bleeding and abdominal pain. | 2011 | J. Pediatr. Gastroenterol. Nutr. | pmid:21970991 |
Heath AP et al. | An algorithm for efficient identification of branched metabolic pathways. | 2011 | J. Comput. Biol. | pmid:21999288 |
Ho PL et al. | Changes in nasopharyngeal carriage and serotype distribution of antibiotic-resistant Streptococcus pneumoniae before and after the introduction of 7-valent pneumococcal conjugate vaccine in Hong Kong. | 2011 | Diagn. Microbiol. Infect. Dis. | pmid:22000087 |
Del Grosso M et al. | Genetic resistance elements carrying mef subclasses other than mef(A) in Streptococcus pyogenes. | 2011 | Antimicrob. Agents Chemother. | pmid:21502613 |
Loreto ES et al. | In vitro susceptibility of Pythium insidiosum to macrolides and tetracycline antibiotics. | 2011 | Antimicrob. Agents Chemother. | pmid:21537028 |
Nakamura PA et al. | Antimicrobial resistance profiles and genetic characterisation of macrolide resistant isolates of Streptococcus agalactiae. | 2011 | Mem. Inst. Oswaldo Cruz | pmid:21537668 |
Shaala LA et al. | Brominated arginine-derived alkaloids from the red sea sponge Suberea mollis. | 2011 | J. Nat. Prod. | pmid:21542602 |
Zhao DL et al. | Characterization of a cryptic plasmid pSM429 and its application for heterologous expression in psychrophilic Pseudoalteromonas. | 2011 | Microb. Cell Fact. | pmid:21542941 |
Chen HX et al. | [Compound erythromycin sustained release preparation and its in vitro release]. | 2011 | Yao Xue Xue Bao | pmid:22260035 |
Wei Z et al. | [Treatment of low-dose erythromycin and sinus displacement on sinusitis in patients with nasopharyngeal carcinoma after radiotherapy]. | 2011 | Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi | pmid:22260078 |
Ezhova NM et al. | [Molecularly imprinted hydrophilic polymer sorbents for selective sorption of erythromycin]. | 2011 Nov-Dec | Prikl. Biokhim. Mikrobiol. | pmid:22288199 |
Henningsen E and Bygum A | Budesonide-induced periorificial dermatitis presenting as chalazion and blepharitis. | 2011 Sep-Oct | Pediatr Dermatol | pmid:21895758 |
Abdel Fattah NS and Darwish YW | Antibiogram testing of pediatric skin infections in the era of methicillin-resistant Staphylococci aureus: an Egyptian University Hospital-based study. | 2012 | Int. J. Dermatol. | pmid:22928620 |
Kjeldgaard J et al. | Residual antibiotics disrupt meat fermentation and increase risk of infection. | 2012 | MBio | pmid:22930338 |
Sakatis MZ et al. | Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. | 2012 | Chem. Res. Toxicol. | pmid:22931300 |
Li SL et al. | A single tube modified allele-specific-PCR for rapid detection of erythromycin-resistant Mycoplasma pneumoniae in Beijing. | 2012 | Chin. Med. J. | pmid:22931973 |
Waśko A et al. | Genetic mechanisms of variation in erythromycin resistance in Lactobacillus rhamnosus strains. | 2012 | J. Antibiot. | pmid:22948255 |
Counsell H | An abdominal mass in a 4-year-old child. | 2012 | BMJ Case Rep | pmid:22922923 |
Leyden JJ | In vivo antibacterial effects of tretinoin-clindamycin and clindamycin alone on Propionibacterium acnes with varying clindamycin minimum inhibitory. | 2012 | J Drugs Dermatol | pmid:23377513 |
Hess TM and Chew HF | Successful treatment of acute ocular involvement in Stevens-Johnson syndrome with amniotic membrane transplantation: a case report. | 2012 | Can. J. Ophthalmol. | pmid:23217513 |
Krasniqi S et al. | Blood, tissue, and intracellular concentrations of erythromycin and its metabolite anhydroerythromycin during and after therapy. | 2012 | Antimicrob. Agents Chemother. | pmid:22083477 |
Nimgaonkar A et al. | Gastrointestinal dysmotility. | 2012 | Dig. Dis. Sci. | pmid:22038542 |
Fazeli M et al. | Erythromycin enhances abomasal emptying in healthy unweaned lambs as shown by acetaminophen absorption test. | 2012 | J. Vet. Pharmacol. Ther. | pmid:22066489 |
Kumar R et al. | Synthesis and antibacterial activity of a novel series of acylides active against community acquired respiratory pathogens. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22153939 |
Reutenauer-Patte J et al. | Urocortins improve dystrophic skeletal muscle structure and function through both PKA- and Epac-dependent pathways. | 2012 | Am. J. Pathol. | pmid:22192627 |
Villaseñor-Sierra A et al. | Phenotypes and genotypes of erythromycin-resistant Streptococcus pyogenes strains isolated from invasive and non-invasive infections from Mexico and the USA during 1999-2010. | 2012 | Int. J. Infect. Dis. | pmid:22217469 |
Luangtongkum T et al. | Impaired fitness and transmission of macrolide-resistant Campylobacter jejuni in its natural host. | 2012 | Antimicrob. Agents Chemother. | pmid:22183170 |
Soeters HM et al. | Trimethoprim-sulfamethoxazole prophylaxis and antibiotic nonsusceptibility in invasive pneumococcal disease. | 2012 | Antimicrob. Agents Chemother. | pmid:22232291 |
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Mansouri-najand L et al. | Prevalence of multidrug resistance Campylobacter jejuni and Campylobacter coli in chickens slaughtered in selected markets, Malaysia. | 2012 | Trop Biomed | pmid:22735845 |
Janssen BD et al. | Analysis of aminoacyl- and peptidyl-tRNAs by gel electrophoresis. | 2012 | Methods Mol. Biol. | pmid:22736012 |
Shi JG et al. | The effect of CYP3A4 inhibition or induction on the pharmacokinetics and pharmacodynamics of orally administered ruxolitinib (INCB018424 phosphate) in healthy volunteers. | 2012 | J Clin Pharmacol | pmid:21602517 |
Gokmen T et al. | A controlled trial of erythromycin and UDCA in premature infants during parenteral nutrition in minimizing feeding intolerance and liver function abnormalities. | 2012 | J Perinatol | pmid:21566568 |
Romøren M et al. | Pregnancy outcome after gestational exposure to erythromycin - a population-based register study from Norway. | 2012 | Br J Clin Pharmacol | pmid:22463376 |
Wormser GP et al. | Failure of topical antibiotics to prevent disseminated Borrelia burgdorferi infection following a tick bite in C3H/HeJ mice. | 2012 | J. Infect. Dis. | pmid:21930606 |
Lee CH et al. | Case-crossover design: an alternative strategy for detecting drug-induced liver injury. | 2012 | J Clin Epidemiol | pmid:22445086 |
Blode H et al. | Evaluation of the effects of rifampicin, ketoconazole and erythromycin on the steady-state pharmacokinetics of the components of a novel oral contraceptive containing estradiol valerate and dienogest in healthy postmenopausal women. | 2012 | Contraception | pmid:22445438 |
Kanazu T et al. | Investigation of drug-drug interaction via mechanism-based inhibition of cytochrome P450 3A by macrolides in dexamethasone-treated female rats. | 2012 | Biopharm Drug Dispos | pmid:22447511 |
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Imai Y et al. | Development of the ability to produce secondary metabolites in Streptomyces through the acquisition of erythromycin resistance. | 2012 | J. Antibiot. | pmid:22491137 |
Hellmann-Regen J et al. | Retinoic acid as target for local pharmacokinetic interaction with modafinil in neural cells. | 2012 | Eur Arch Psychiatry Clin Neurosci | pmid:22434147 |
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Mehra T et al. | Treatment of severe acne with low-dose isotretinoin. | 2012 | Acta Derm. Venereol. | pmid:22377969 |
Ogawa W et al. | Functional study of the novel multidrug efflux pump KexD from Klebsiella pneumoniae. | 2012 | Gene | pmid:22391093 |
Diacon AH et al. | Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: long-term outcome, tolerability, and effect on emergence of drug resistance. | 2012 | Antimicrob. Agents Chemother. | pmid:22391540 |
Peano C et al. | Comparative genomics and transcriptional profiles of Saccharopolyspora erythraea NRRL 2338 and a classically improved erythromycin over-producing strain. | 2012 | Microb. Cell Fact. | pmid:22401291 |
Chen CM | Erythromycin for the treatment of feeding intolerance in preterm infants. | 2012 | Pediatr Neonatol | pmid:22348487 |
Ng YY et al. | Efficacy of intermediate-dose oral erythromycin on very low birth weight infants with feeding intolerance. | 2012 | Pediatr Neonatol | pmid:22348492 |
Yoon SB et al. | The effect of exenatide and erythromycin on postprandial symptoms and their relation to gastric functions. | 2012 | Digestion | pmid:22354133 |
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Michael M et al. | Docetaxel pharmacokinetics and its correlation with two in vivo probes for cytochrome P450 enzymes: the C(14)-erythromycin breath test and the antipyrine clearance test. | 2012 | Cancer Chemother. Pharmacol. | pmid:21626050 |
Chhun S et al. | The cytochrome P-450 2C9/2C19 but not the ABCB1 genetic polymorphism may be associated with the liver cytochrome 3A4 induction by phenytoin. | 2012 | J Clin Psychopharmacol | pmid:22561479 |
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Pendela M et al. | Combined use of liquid chromatography with mass spectrometry and nuclear magnetic resonance for the identification of degradation compounds in an erythromycin formulation. | 2012 | Anal Bioanal Chem | pmid:22002558 |
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Giovanetti E et al. | ICESp2905, the erm(TR)-tet(O) element of Streptococcus pyogenes, is formed by two independent integrative and conjugative elements. | 2012 | Antimicrob. Agents Chemother. | pmid:21986826 |
Zhou L et al. | Molecular characteristics of erythromycin-resistant Streptococcus pneumoniae from pediatric patients younger than five years in Beijing, 2010. | 2012 | BMC Microbiol. | pmid:23043378 |
Cannon JA et al. | Preoperative oral antibiotics reduce surgical site infection following elective colorectal resections. | 2012 | Dis. Colon Rectum | pmid:23044677 |
Kaul M et al. | A bactericidal guanidinomethyl biaryl that alters the dynamics of bacterial FtsZ polymerization. | 2012 | J. Med. Chem. | pmid:23050700 |
Du Plessis LH et al. | In vitro activity of Pheroid vesicles containing antibiotics against Plasmodium falciparum. | 2012 | J. Antibiot. | pmid:23093037 |
Brenciani A et al. | ICESp1116, the genetic element responsible for erm(B)-mediated, inducible resistance to erythromycin in Streptococcus pyogenes. | 2012 | Antimicrob. Agents Chemother. | pmid:23027190 |
PiÄ…tkowska E et al. | The strongest resistance of Staphylococcus aureus to erythromycin is caused by decreasing uptake of the antibiotic into the cells. | 2012 | Cell. Mol. Biol. Lett. | pmid:23001512 |
Leiding JW et al. | Successful sirolimus graded dose challenge in an erythromycin-allergic patient. | 2012 | Ann. Allergy Asthma Immunol. | pmid:23010239 |
Marks LR et al. | The human milk protein-lipid complex HAMLET sensitizes bacterial pathogens to traditional antimicrobial agents. | 2012 | PLoS ONE | pmid:22905269 |
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