erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Uglov FG et al. | [The use of antibiotics in surgical practice]. | 1967 | Vestn. Khir. Im. I. I. Grek. | pmid:4304565 |
Donaldson MH and Thurman WG | An approach to acute respiratory infection in children. | 1967 | Ann. N. Y. Acad. Sci. | pmid:4397880 |
Cramblett HG and Azimi PH | Role of Hemophilus influenzae in pediatric respiratory infections. | 1967 | Ann. N. Y. Acad. Sci. | pmid:4397883 |
Afanas'ev BA | [Erythromycin in the treatment of gonorrhea in women]. | 1967 | Vestn Dermatol Venerol | pmid:5611849 |
Apirion D | Three genes that affect Escherichia coli ribosomes. | 1967 | J. Mol. Biol. | pmid:4870510 |
Duncan IB | Development of lincomycin resistance by staphylococci. | 1967 | Antimicrob Agents Chemother (Bethesda) | pmid:5596212 |
Paukert H and Markalous E | [New therapy of dermatomyositis and scleroderma]. | 1967 | Dermatol Wochenschr | pmid:5600184 |
Garanin BA | [Sensitivity toward antibiotics of enteropathogenic Escherichia coli. (According to data from a hospital for infectious diseases)]. | 1967 | Antibiotiki | pmid:4871267 |
Segal J | [Clinico-paracytological and therapeutic study with a new preparation of erythromycin stearate of controlled release (A-16535) in intestinal amebiasis]. | 1967 | Rev Bras Med | pmid:5603001 |
Levy A et al. | [Sustained-release erythromycin sterate in the therapy of intestinal amebiasis]. | 1967 | Rev Bras Med | pmid:5604985 |
Blinov NO and Khokhlov AS | [Paper chromatography and electrophoresis in the study of the transformation of antibiotics in the human and animal body]. | 1967 | Antibiotiki | pmid:4874768 |
Maichuk IuF | [Antibiotics in polyvinyl alcohol film for treatment of infectious eye diseases]. | 1967 | Antibiotiki | pmid:4874770 |
Wagner JG and Metzler CM | Estimation of rate constants for absorption and elimination from blood concentration data. | 1967 | J Pharm Sci | pmid:6032790 |
Levitov MM and Brinberg SL | [Physiology of antibiotic-producing microorganisms and the process of biosynthesis of antibiotics]. | 1967 | Antibiotiki | pmid:4875265 |
Popovici GG et al. | The influence of some antibiotics on uterine motor activity in the guinea pig. | 1967 | Arch Int Pharmacodyn Ther | pmid:6034322 |
Kuzel NR and Coffey HF | Automated analysis of erythromycin. | 1967 | J Pharm Sci | pmid:6034553 |
Richmond MH | A second regulatory region involved in penicillinase synthesis in Staphylococcus aureus. | 1967 | J. Mol. Biol. | pmid:6034780 |
Celmer WD and Ebringer L | Effects of certain O-acyl derivatives of oleandomycin and erythromycin on chloroplasts of Euglena gracilis. | 1967 | J. Protozool. | pmid:6038034 |
Perun TJ | Chemistry of erythronolide B. Acid-catalyzed transformations of the aglycone of erythromycin B. | 1967 | J. Org. Chem. | pmid:6046179 |
Djokić S and Tamburasĕv Z | Erythromycin study: 9-amino-3-O-cladinosyl-5-O-desosaminyl-6,11,12-tryhydroxy-2,4,6,8,10,12-hexamethylpentadecane-13-olide. | 1967 | Tetrahedron Lett. | pmid:6047192 |
Martin JR and Rosenbrook W | Studies on the biosynthesis of the erythromycins. II. Isolation and structure of a biosynthetic intermediate, 6-deoxyerythronolide B. | 1967 | Biochemistry | pmid:6047629 |
Stelińska A et al. | [Observations on the effectiveness of erythromycin activity on the bacterial flora of dental origin]. | 1967 | Czas Stomatol | pmid:5234368 |
Merklen FP and Renoux M | [Antibiotics other than penicillin in the treatment of syphilis]. | 1967 | Rev Fr Odontostomatol | pmid:5235420 |
Kalowski M and Romankiewicz GE | [Effect of penicillin and erythromycin on the inhibition of rampant dental caries in golden hamsters]. | 1967 | Czas Stomatol | pmid:5235543 |
Cundliffe E and McQuillen K | Bacterial protein synthesis: the effects of antibiotics. | 1967 | J. Mol. Biol. | pmid:4965676 |
Monnier J and Bourse R | [Cross-resistance in macrolids and related groups]. | 1967 | Pathol Biol | pmid:4867325 |
Leonard JR | Prophylactic antibiotics in human stapedectomy. | 1967 | Laryngoscope | pmid:6023620 |
Dechaume M et al. | [Clinical stomatologic studies of erythromycine stearate and erythromycine ethyl-succinate]. | 1967 | Inf Dent | pmid:5235751 |
Purcell RH and Chanock RM | Role of mycoplasmas in human respiratory disease. | 1967 | Med. Clin. North Am. | pmid:6023805 |
Haraguchi I et al. | [Clinico-pathological study on the effect of erythromycin on pulp tissue]. | 1967 | Shikwa Gakuho | pmid:5236258 |
McGovern JP et al. | Bacterial infection in children with respiratory allergy: bacteriologic findings and therapy. | 1967 | South. Med. J. | pmid:6024614 |
Takei M et al. | [Studies on the mixed culture of Candida and Lactobacillus. 3. Influences of the antibiotics (EM and TM)]. | 1967 | Aichi Gakuin Daigaku Shigakkai Shi | pmid:5236280 |
Chang FN and Weisblum B | The specificity of lincomycin binding to ribosomes. | 1967 | Biochemistry | pmid:6025566 |
Molan PC and Hartles RL | The source of glycolytic activity in human saliva. | 1967 | Arch. Oral Biol. | pmid:5237340 |
Rosenberg IH et al. | Abnormal bile-salt patterns and intestinal bacterial overgrowth associated with malabsorption. | 1967 | N. Engl. J. Med. | pmid:6026403 |
Wassermann D | Acute paranasal sinusitis and cavernous sinus thrombosis. | 1967 | Arch Otolaryngol | pmid:6029348 |
Cernea P and Devien CV | [Therapeutic value of a new comined antibiotic therapy]. | 1967 | Rev Fr Odontostomatol | pmid:5238749 |
Sugiyama H | [Experimental studies on control of dental caries. 1. Preventive effect of Erythromycin]. | 1967 | Aichi Gakuin Daigaku Shigakkai Shi | pmid:5244796 |
Kislak JW | Type 6 pneumococcus resistant to erythromycin and lincomycin. | 1967 | N. Engl. J. Med. | pmid:4381364 |
Vasil'eva NG and Poliak MS | [Microflora of sputum in pneumonias and its sensitivity to antibiotics]. | 1967 | Antibiotiki | pmid:4386255 |
Green GR et al. | Treatment of bacterial endocarditis in patients with penicillin hypersensitivity. | 1967 | Ann. Intern. Med. | pmid:4382501 |
Isenberg HD | In vitro activity of doxycycline against bacteria from clinical material. | 1967 | Appl Microbiol | pmid:4383870 |
Pap H and Grisebach H | [Inhibition of erythromycin synthesis in S. erythreus by alph-and beta-fluoropropionic acid]. | 1967 | Z. Naturforsch. B | pmid:4384761 |
Simon HJ | Antimicrobial susceptibility of group D hemolytic streptococci (enterococci). | 1967 | Am. J. Med. Sci. | pmid:5180810 |
Benner EJ and Morthland V | Methicillin-resistant Staphylococcus aureus. Antimicrobial susceptibility. | 1967 | N. Engl. J. Med. | pmid:5182623 |
Rédai I et al. | Fatty acid composition of Staphylococcus aureus strains differing in antibiotic sensitivity. | 1967 | Acta Microbiol Acad Sci Hung | pmid:5183078 |
Gutman LT et al. | Bacterial L-forms in relapsing urinary-tract infection. | 1967 | Lancet | pmid:4164065 |
Weisblum B | Pneumococcus resistant to erythromycin and lincomycin. | 1967 | Lancet | pmid:4164310 |
Jensen K | [Combination therapy with antibacterial chemotherapeutic agents in staphylococcal infections]. | 1967 | Ugeskr. Laeg. | pmid:5187979 |
Slotkin RI et al. | The effect of antibiotics on Mycoplasma pneumoniae in vitro and in vivo. | 1967 | Am. J. Epidemiol. | pmid:5006447 |
Sugano T et al. | [Results in the combined use of nalidixic acid with other drugs for bacillary dysentery]. | 1967 | Nihon Densenbyo Gakkai Zasshi | pmid:4968896 |
Kuzin MI et al. | [Efficacy of kanamycin in surgical infection. (Experimental-clinical study)]. | 1967 | Antibiotiki | pmid:4969447 |
Smolianskaia AZ and Grinenko GI | [Dissemination of bacteria with multiple drug resistance in patients in the Oncological Clinic]. | 1967 | Antibiotiki | pmid:4970184 |
Wilhelm JM et al. | Interaction of antibiotics with ribosomes: structure-function relationships and a possible common mechanism for the antibacterial action of the macrolides and lincomycin. | 1967 | Antimicrob Agents Chemother (Bethesda) | pmid:4970204 |
Legler F | [Present resistance status of Staphylococcus aureus under specific consideration of the antibiotics virgimycia, cephalothin and fusidic acid]. | 1967 | Arzneimittelforschung | pmid:4974419 |
Hejzlar M et al. | Cephaloridine. II. The effect of cephaloridine on experimental model infections. | 1967 | J Hyg Epidemiol Microbiol Immunol | pmid:5629908 |
Kaltiala EH et al. | Subchronic toxicity of some erythromycin compounds in rats. | 1967 | Acta Pharmacol Toxicol (Copenh) | pmid:5630681 |
Larson RH et al. | The interaction of diet and microflora in experimental caries in the rat. | 1967 | Arch. Oral Biol. | pmid:5228613 |
Novick R | Properties of a cryptic high-frequency transducing phage in Staphylococcus aureus. | 1967 | Virology | pmid:4227577 |
Lucas JB and Price EV | Co-operative evaluation of treatment for early syphilis. Preliminary report with special reference to spectinomycin sulphate (actinospectacin). | 1967 | Br J Vener Dis | pmid:4230278 |
Luba J and Ulikowski S | [Effect of bacterial infections of fermentative medium on erythromycin biosynthesis]. | 1967 | Acta Pol Pharm | pmid:5583960 |
Olsen H | The sensitivity of Flavobacterium meningosepticum to antibiotics at different temperatures. An in vitro study. | 1967 | Acta Pathol Microbiol Scand | pmid:5584517 |
Balashova II and Khomiakova VI | [Treatment of staphylococcal infections in children by monomycin, neomycin, erythromycin and oletetrin]. | 1967 | Antibiotiki | pmid:5585720 |
Heydenreich A | [Intraocular application of antibiotics]. | 1967 | Klin Monbl Augenheilkd | pmid:5586135 |
Nussbaumer PA | [A contribution to the study of erythromycin by means of thin-layer chromatography. 1. Stability in aquenous medium]. | 1967 | Pharm Acta Helv | pmid:5586792 |
Voiculescu M et al. | [Sensitivity of beta-hemolytic streptococcus, group A, isolated from streptococcal infections, to different antibiotics and sulfonamides]. | 1967 | Schweiz Med Wochenschr | pmid:5587438 |
Barbier P et al. | [Progressive experimental biliary obstruction. IV. Biliary concentration of antibiotics]. | 1967 | C. R. Seances Soc. Biol. Fil. | pmid:4234166 |
Hughes WT and Wan RT | Impetigo contagiosa: etiology, complications, and comparison of therapeutic effectiveness of erythromycin and antibiotic ointment. | 1967 | Am. J. Dis. Child. | pmid:4290285 |
Smits H and Freedman LR | Prolonged venous catheterization as a cause of sepsis. | 1967 | N. Engl. J. Med. | pmid:4290392 |
Zegarelli EV et al. | Discoloration of the teeth in a 24-year-old patient with cystic fibrosis of the pancreas not primarily associated with tetracycline therapy. Report of a case. | 1967 | Oral Surg. Oral Med. Oral Pathol. | pmid:4291199 |
Williams ST | Sensitivity of streptomycetes to antibiotics as a taxonomic character. | 1967 | J. Gen. Microbiol. | pmid:4291590 |
Sterner G et al. | A comparative trial of cephaloridine and erythromycin in hospitalized pneumonic patients. | 1967 | Postgrad Med J | pmid:4861117 |
Clinical useful antimicrobial agents. General considerations concerning chloramphenicol, erythromycin and allied drugs, the polymyxins, bacitracin, vancomycin, ristocetin, cycloserine, the cephalosporins, the chemotherapeutic drugs and the antimycotic drugs. | 1967 | Postgrad Med | pmid:4293380 | |
Smith CB et al. | Mycoplasma pneumoniae infections in volunteers. | 1967 | Ann. N. Y. Acad. Sci. | pmid:4861142 |
Clinically useful antimicrobial agents. Dosage and mode of administration. | 1967 | Postgrad Med | pmid:4293381 | |
Clinically useful antimicrobial agents. Untoward reactions. | 1967 | Postgrad Med | pmid:4293382 | |
Roberts DS | Chemotherapy of epidermal infection with Dermatophilus congolensis. | 1967 | J. Comp. Pathol. | pmid:4166506 |
Mehta BM et al. | Evidence of genetic transformation in Streptococcus faecium var. durans (SF-O). | 1967 | J. Bacteriol. | pmid:6051354 |
Golenia A and Rafińska J | [Contribution to the treatment of staphylococcal pericarditis]. | 1967 | Pediatr Pol | pmid:6052305 |
Treatment of atypical pneumonia. | 1967 | Med Lett Drugs Ther | pmid:6052695 | |
Armstrong BK and Curnow DH | The effect of streptomycin and erythromycin on vitamin B12 nutrition in rats in which coprophagy was prevented. | 1967 | Br. J. Nutr. | pmid:6052871 |
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Manchester KL | Effects of antibiotics of protein synthesis in muscle and implications with regard to the action of insulin. | 1967 | Nature | pmid:6053821 |
Gol'dat SIu et al. | [Achievements of Soviet selection of strains--producers of antibiotics]. | 1967 | Antibiotiki | pmid:4298569 |
Schiatti P et al. | Biliary excretion rate of semisynthetic rifamycins in the rat. | 1967 | Chemotherapy | pmid:6055273 |
Münchow P | [Antibiotics 19]. | 1967 | Pharm Prax | pmid:4177256 |
Schuster W | [On the length of resorption of pneumonia infiltration under antibiotic therapy]. | 1967 | Dtsch. Med. Wochenschr. | pmid:6060872 |
Shneerson AN and Rezvan SP | [Staphylococci resistant to semisynthetic penicillins, isolated from patients]. | 1967 | Antibiotiki | pmid:4298633 |
Wyman JB et al. | Excretion of antibiotics in pancreatic juice: studies in dogs with normal pancreas and with acute pancreatitis. | 1967 | Gastroenterology | pmid:6065004 |
Khokhlov AS | [Development of antibiotic chemistry in the USSR]. | 1967 | Antibiotiki | pmid:4299071 |
Warren GH and Gray J | Effect of antimicrobial drug combinations on enzymic lysis of Staphylococcus aureus. | 1967 | Proc. Soc. Exp. Biol. Med. | pmid:6066156 |
Tarizzo ML and Nabli B | The effect of antibiotics on the growth of TRIC agents in embryonated eggs. | 1967 | Am. J. Ophthalmol. | pmid:6067315 |
Ghione M et al. | Research on factors influencing experimental chemotherapy tests in trachoma. | 1967 | Am. J. Ophthalmol. | pmid:6067316 |
Chernomordik AB | [Synergistic action of antibiotics on Bacillus pyocianaeus]. | 1967 | Antibiotiki | pmid:4300088 |
Golub B et al. | Lung abscess due to Corynebacterium equi. Report of first human infection. | 1967 | Ann. Intern. Med. | pmid:6067513 |
Lantos J | Change in the phage type of Staphylococcus aureus as a result of lysogenizatio. | 1967 | Acta Microbiol Acad Sci Hung | pmid:4300285 |
Olson NO | Efficacy of furaltadone in drinking water or feed against an artificial infection of infectious synovitis in chickens. | 1967 | Avian Dis. | pmid:6067602 |
DoutlÃk S et al. | Electroencephalographic changes after intravenous administration of antibiotics. | 1967 | Arzneimittelforschung | pmid:4300334 |
von Wasielewski E and Schütze E | [Treatment with antibiotic agents with special reference to their relation to otorhinolaryngology]. | 1967 | Arch Klin Exp Ohren Nasen Kehlkopfheilkd | pmid:4300371 |
Yousef RT et al. | An agar disc method for testing the sensitivity of microorganisms to antibiotics. | 1967 | Arzneimittelforschung | pmid:4303563 |