erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (20)
- J. Antimicrob. Chemother. (9)
- Drug Metab. Dispos. (2)
- Others (20)
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Namikawa H et al. | Effect of erythromycin A and its new derivative EM201 on type I collagen production by cultured dermal fibroblasts. | 2010 | Arch. Dermatol. Res. | pmid:19578864 |
| Meinertz JR et al. | Chronic toxicity of diphenhydramine hydrochloride and erythromycin thiocyanate to daphnia, Daphnia magna, in a continuous exposure test system. | 2010 | Bull Environ Contam Toxicol | pmid:20976439 |
| Dhamdhere G et al. | Interplay between drug efflux and antioxidants in Escherichia coli resistance to antibiotics. | 2010 | Antimicrob. Agents Chemother. | pmid:20876376 |
| He ZY et al. | Effect of 6 months of erythromycin treatment on inflammatory cells in induced sputum and exacerbations in chronic obstructive pulmonary disease. | 2010 | Respiration | pmid:20881376 |
| Demirkan A et al. | Endotoxin level in ischemia-reperfusion injury in rats: effect of glutamine pretreatment on endotoxin levels and gut morphology. | 2010 | Nutrition | pmid:19596185 |
| Liu Y et al. | 9-Dihydroerythromycin ethers as motilin agonists--developing structure-activity relationships for potency and safety. | 2010 | Bioorg. Med. Chem. | pmid:20869254 |
| Kiely RA et al. | Analysis of phenotype, genotype and serotype distribution in erythromycin-resistant group B streptococci isolated from vaginal flora in Southern Ireland. | 2010 | Epidemiol. Infect. | pmid:19602300 |
| Leszczyńska K et al. | Modulation of exogenous antibiotic activity by host cathelicidin LL-37. | 2010 | APMIS | pmid:20955455 |
| Atkins JL et al. | Enhancement of antimicrobial activity by synthetic ion channel synergy. | 2010 | Chem. Commun. (Camb.) | pmid:20931142 |
| Keurulainen L et al. | Design and synthesis of 2-arylbenzimidazoles and evaluation of their inhibitory effect against Chlamydia pneumoniae. | 2010 | J. Med. Chem. | pmid:20932010 |
| Dunkle JA et al. | Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20876128 |
| Bulkley D et al. | Revisiting the structures of several antibiotics bound to the bacterial ribosome. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20876130 |
| Yang M et al. | Macrolides for diffuse panbronchiolitis. | 2010 | Cochrane Database Syst Rev | pmid:21154381 |
| van der Beek MT et al. | Inaccuracy of routine susceptibility tests for detection of erythromycin resistance of Campylobacter jejuni and Campylobacter coli. | 2010 | Clin. Microbiol. Infect. | pmid:19438640 |
| Aguilera R C et al. | [Antimicrobial susceptibility, capsular serotypes and clonal relationship of invasive streptococcus pneumoniae isolates in adult population of the Bio-Bio region, Chile. 2005-2006]. | 2010 | Rev Chilena Infectol | pmid:21186502 |
| Cetin ES et al. | Distribution of genes encoding resistance to macrolides, lincosamides and streptogramins among clinical staphylococcal isolates in a Turkish university hospital. | 2010 | J Microbiol Immunol Infect | pmid:21195981 |
| Pires R et al. | Emergence of ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates from healthy children and pediatric patients in Portugal. | 2010 | Antimicrob. Agents Chemother. | pmid:20350943 |
| Duranti R | Long-term treatment with macrolides - light in the darkness of COPD therapy? | 2010 | Respiration | pmid:21079411 |
| Fomda BA et al. | Phenotypic detection of constitutive and inducible clindamycin resistance in clinical isolates of Staphylococcus aureus and coagulase negative Staphylococcus on routine susceptibility plate. | 2010 | J Commun Dis | pmid:22468547 |
| Pazoki-Toroudi H et al. | Combination of azelaic acid 5% and erythromycin 2% in the treatment of acne vulgaris. | 2010 | J Dermatolog Treat | pmid:20394495 |
| Fluhr JW and Degitz K | [Antibiotics, azelaic acid and benzoyl peroxide in topical acne therapy]. | 2010 | J Dtsch Dermatol Ges | pmid:20482689 |
| Kamal N and Shafer WM | Biologic activities of the TolC-like protein of Neisseria meningitidis as assessed by functional complementation in Escherichia coli. | 2010 | Antimicrob. Agents Chemother. | pmid:19884363 |
| McGhee P et al. | In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms. | 2010 | Antimicrob. Agents Chemother. | pmid:19884376 |
| Florindo C et al. | Molecular characterization and antimicrobial susceptibility profiles in Streptococcus agalactiae colonizing strains: association of erythromycin resistance with subtype III-1 genetic clone family. | 2010 | Clin. Microbiol. Infect. | pmid:19886900 |
| Stringer E et al. | Treatment of trichomoniasis in pregnancy in sub-Saharan Africa does not appear to be associated with low birth weight or preterm birth. | 2010 | S. Afr. Med. J. | pmid:20429491 |
| Ohlsson B et al. | Antibodies against gonadotropin-releasing hormone (GnRH) and destruction of enteric neurons in 3 patients suffering from gastrointestinal dysfunction. | 2010 | BMC Gastroenterol | pmid:20487533 |
| Kokolakis GP et al. | Guttate psoriasis occurring on varicella lesions. | 2010 | J. Dermatol. | pmid:20883381 |
| Chandra B et al. | Catalytic asymmetric synthesis of complex polypropionates: Lewis base catalyzed aldol equivalents in the synthesis of erythronolide B. | 2010 | Angew. Chem. Int. Ed. Engl. | pmid:20209542 |
| Kadlec K and Schwarz S | Identification of a plasmid-borne resistance gene cluster comprising the resistance genes erm(T), dfrK, and tet(L) in a porcine methicillin-resistant Staphylococcus aureus ST398 strain. | 2010 | Antimicrob. Agents Chemother. | pmid:20008780 |
| Yim N et al. | The antimicrobial activity of compounds from the leaf and stem of Vitis amurensis against two oral pathogens. | 2010 | Bioorg. Med. Chem. Lett. | pmid:20022753 |
| Chen B et al. | Study on enantiomeric separation of basic drugs by NACE in methanol-based medium using erythromycin lactobionate as a chiral selector. | 2010 | Electrophoresis | pmid:20024923 |
| Yao J et al. | Novel enoyl-ACP reductase (FabI) potential inhibitors of Escherichia coli from Chinese medicine monomers. | 2010 | Bioorg. Med. Chem. Lett. | pmid:19959361 |
| Tokuda A et al. | Effects of macrolides on antigen-induced increases in cough reflex sensitivity in guinea pigs. | 2010 | Pulm Pharmacol Ther | pmid:19835975 |
| Padilla E et al. | Klebsiella pneumoniae AcrAB efflux pump contributes to antimicrobial resistance and virulence. | 2010 | Antimicrob. Agents Chemother. | pmid:19858254 |
| Glass SK et al. | Canadian province-level risk factor analysis of macrolide consumption patterns (2000-2006). | 2010 | J. Antimicrob. Chemother. | pmid:19864333 |
| Goetting-Minesky MP and Fenno JC | A simplified erythromycin resistance cassette for Treponema denticola mutagenesis. | 2010 | J. Microbiol. Methods | pmid:20691222 |
| Mazzoncini JP et al. | Human metapneumovirus: an emerging respiratory pathogen. | 2010 | J Emerg Med | pmid:18584996 |
| Banche G et al. | Synergistic effect of erythromycin on polymorphonuclear cell antibacterial activity against erythromycin-resistant phenotypes of Streptococcus pyogenes. | 2010 | Int. J. Antimicrob. Agents | pmid:20692129 |
| Shi HY et al. | Effects of erythromycin on voriconazole pharmacokinetics and association with CYP2C19 polymorphism. | 2010 | Eur. J. Clin. Pharmacol. | pmid:20669013 |
| Accinelli C et al. | Removal of oseltamivir (Tamiflu) and other selected pharmaceuticals from wastewater using a granular bioplastic formulation entrapping propagules of Phanerochaete chrysosporium. | 2010 | Chemosphere | pmid:20673959 |
| Miyashita N et al. | Macrolide-resistant Mycoplasma pneumoniae in adults with community-acquired pneumonia. | 2010 | Int. J. Antimicrob. Agents | pmid:20674283 |
| Liu H et al. | Erythromycin inhibited glycinergic inputs to gastric vagal motoneurons in brainstem slices of newborn rats. | 2010 | Neurogastroenterol. Motil. | pmid:20731779 |
| Biedenbach DJ et al. | In vitro activity of fidaxomicin (OPT-80) tested against contemporary clinical isolates of Staphylococcus spp. and Enterococcus spp. | 2010 | Antimicrob. Agents Chemother. | pmid:20308391 |
| Wang Q et al. | Enhancement of biofilm formation by subinhibitory concentrations of macrolides in icaADBC-positive and -negative clinical isolates of Staphylococcus epidermidis. | 2010 | Antimicrob. Agents Chemother. | pmid:20231401 |
| DeFelice T et al. | A red plaque on the cheek. | 2010 | Dermatol. Online J. | pmid:20233564 |
| Bourne CR et al. | Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1. | 2010 | Antimicrob. Agents Chemother. | pmid:20606069 |
| Bohnert JA et al. | Optimized Nile Red efflux assay of AcrAB-TolC multidrug efflux system shows competition between substrates. | 2010 | Antimicrob. Agents Chemother. | pmid:20606071 |
| Horner P | Chlamydia (uncomplicated, genital). | 2010 | BMJ Clin Evid | pmid:21718568 |
| Ren W et al. | Efficacy of periprosthetic erythromycin delivery for wear debris-induced inflammation and osteolysis. | 2010 | Inflamm. Res. | pmid:20607583 |
| Ortiz-Pérez A et al. | High frequency of macrolide resistance mechanisms in clinical isolates of Corynebacterium species. | 2010 | Microb. Drug Resist. | pmid:20624090 |
| Dundar D et al. | Macrolide and tetracycline resistance and emm type distribution of Streptococcus pyogenes isolates recovered from Turkish patients. | 2010 | Microb. Drug Resist. | pmid:20624096 |
| Biedenbach DJ et al. | Determination of CEM-101 activity tested against clinical isolates of Neisseria meningitidis from a worldwide collection. | 2010 | Antimicrob. Agents Chemother. | pmid:20625152 |
| Ilchmann C et al. | Comparison of resistance against erythromycin and moxifloxacin, presence of binary toxin gene and PCR ribotypes in Clostridium difficile isolates from 1990 and 2008. | 2010 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:20632051 |
| Kapur S et al. | Molecular recognition between ketosynthase and acyl carrier protein domains of the 6-deoxyerythronolide B synthase. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21127271 |
| Pavlović D and Mutak S | Synthesis and structure-activity relationships of novel 8a-aza-8a-homoerythromycin A ketolides. | 2010 | J. Med. Chem. | pmid:20684614 |
| Elmorsy S et al. | Sinus aspirates in chronic rhinosinusitis: fungal colonization of paranasal sinuses, evaluation of ICAM-1 and IL-8 and studying of immunological effect of long-term macrolide therapy. | 2010 | Rhinology | pmid:21038022 |
| Zhang H et al. | Investigating the role of native propionyl-CoA and methylmalonyl-CoA metabolism on heterologous polyketide production in Escherichia coli. | 2010 | Biotechnol. Bioeng. | pmid:19806677 |
| Wu J et al. | Construction and performance of heterologous polyketide-producing K-12- and B-derived Escherichia coli. | 2010 | Lett. Appl. Microbiol. | pmid:20565574 |
| Harris JB et al. | Cholera's western front. | 2010 | Lancet | pmid:21112083 |
| Pavlović D et al. | Novel hybrids of 15-membered 8a- and 9a-azahomoerythromycin A ketolides and quinolones as potent antibacterials. | 2010 | Bioorg. Med. Chem. | pmid:21055953 |
| Muñoz-Ochoa M et al. | Screening of extracts of algae from Baja California sur, Mexico as reversers of the antibiotic resistance of some pathogenic bacteria. | 2010 | Eur Rev Med Pharmacol Sci | pmid:21061832 |
| Horn JR | Analysis of purported erythromycin-warfarin interaction. | 2010 | Am J Health Syst Pharm | pmid:20516463 |
| Fry NK et al. | Antimicrobial susceptibility testing of historical and recent clinical isolates of Bordetella pertussis in the United Kingdom using the Etest method. | 2010 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:20521155 |
| Cane DE | Programming of erythromycin biosynthesis by a modular polyketide synthase. | 2010 | J. Biol. Chem. | pmid:20522551 |
| Zou S et al. | Isolation, identification of Streptococcus pneumoniae from infected rhesus monkeys and control efficacy. | 2010 | J. Med. Primatol. | pmid:20524954 |
| Kwatra D et al. | Interaction of gatifloxacin with efflux transporters: a possible mechanism for drug resistance. | 2010 | Int J Pharm | pmid:20573570 |
| Ying L and Tang D | Recent advances in the medicinal chemistry of novel erythromycin-derivatized antibiotics. | 2010 | Curr Top Med Chem | pmid:20536419 |
| Fernandes NF et al. | Pityriasis lichenoides et varioliformis acuta: a disease spectrum. | 2010 | Int. J. Dermatol. | pmid:20465660 |
| El-Mahdy TS et al. | Detection of a new erm(X)-mediated antibiotic resistance in Egyptian cutaneous propionibacteria. | 2010 | Anaerobe | pmid:20541615 |
| Kana BD et al. | Depletion of resuscitation-promoting factors has limited impact on the drug susceptibility of Mycobacterium tuberculosis. | 2010 | J. Antimicrob. Chemother. | pmid:20542905 |
| Kadlec K and Schwarz S | Identification of the novel dfrK-carrying transposon Tn559 in a porcine methicillin-susceptible Staphylococcus aureus ST398 strain. | 2010 | Antimicrob. Agents Chemother. | pmid:20498309 |
| Levêque D et al. | [Mechanisms of pharmacokinetic drug-drug interactions]. | 2010 | Rev Med Interne | pmid:19740579 |
| Gunell M et al. | In vitro activity of azithromycin against nontyphoidal Salmonella enterica. | 2010 | Antimicrob. Agents Chemother. | pmid:20498312 |
| Zähner D et al. | Human antimicrobial peptide LL-37 induces MefE/Mel-mediated macrolide resistance in Streptococcus pneumoniae. | 2010 | Antimicrob. Agents Chemother. | pmid:20498319 |
| Mima T and Schweizer HP | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. | 2010 | Antimicrob. Agents Chemother. | pmid:20498323 |
| Kharfi M et al. | Linear IgA bullous dermatosis: the more frequent bullous dermatosis of children. | 2010 | Dermatol. Online J. | pmid:20137744 |
| Martinez-Diaz GJ et al. | A toddler with facial nodules: a case of idiopathic facial aseptic granuloma. | 2010 | Dermatol. Online J. | pmid:20137751 |
| Urakawa H et al. | Structure-activity relationships of bacterial outer-membrane permeabilizers based on polymyxin B heptapeptides. | 2010 | Bioorg. Med. Chem. Lett. | pmid:20138759 |
| Roger PM et al. | [Urinary pneumococcal or Legionella antigen detection tests and low-spectrum antibiotic therapy for community-acquired pneumonia]. | 2010 | Med Mal Infect | pmid:20172672 |
| Gueller S et al. | Identification of defects in the transcriptional program during lineage-specific in vitro differentiation of CD34(+) cells selected from patients with both low- and high-risk myelodysplastic syndrome. | 2010 | Exp. Hematol. | pmid:20621626 |
| Woosley LN et al. | CEM-101 activity against Gram-positive organisms. | 2010 | Antimicrob. Agents Chemother. | pmid:20176910 |
| Mulhbacher J et al. | Novel riboswitch ligand analogs as selective inhibitors of guanine-related metabolic pathways. | 2010 | PLoS Pathog. | pmid:20421948 |
| Morrow BJ et al. | In vitro antibacterial activities of JNJ-Q2, a new broad-spectrum fluoroquinolone. | 2010 | Antimicrob. Agents Chemother. | pmid:20176911 |
| Fraser RJ and Bryant L | Current and future therapeutic prokinetic therapy to improve enteral feed intolerance in the ICU patient. | 2010 | Nutr Clin Pract | pmid:20130155 |
| Cocco G and Gasparyan AY | Myocardial ischemia in Wegener's granulomatosis: coronary atherosclerosis versus vasculitis. | 2010 | Open Cardiovasc Med J | pmid:20360980 |
| Auerbach T et al. | The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20080686 |
| Krenauer A et al. | EBV-associated post-transplantation B-cell lymphoproliferative disorder following allogenic stem cell transplantation for acute lymphoblastic leukaemia: tumor regression after reduction of immunosuppression--a case report. | 2010 | Diagn Pathol | pmid:20356360 |
| Sun H et al. | Hepatic clearance, but not gut availability, of erythromycin is altered in patients with end-stage renal disease. | 2010 | Clin. Pharmacol. Ther. | pmid:20090676 |
| Cousens S et al. | Antibiotics for pre-term pre-labour rupture of membranes: prevention of neonatal deaths due to complications of pre-term birth and infection. | 2010 | Int J Epidemiol | pmid:20348116 |
| Devirgiliis C et al. | Identification of tetracycline- and erythromycin-resistant Gram-positive cocci within the fermenting microflora of an Italian dairy food product. | 2010 | J. Appl. Microbiol. | pmid:20092542 |
| Wang X et al. | Bupropion metabolism by human placenta. | 2010 | Biochem. Pharmacol. | pmid:20109440 |
| Lu NF et al. | [Study of erythromycin and metoclopramide in treatment of feeding intolerance of critically ill patients in intensive care unit]. | 2010 | Zhongguo Wei Zhong Bing Ji Jiu Yi Xue | pmid:20092709 |
| Voisin V et al. | Gene profiling of the erythro- and megakaryoblastic leukaemias induced by the Graffi murine retrovirus. | 2010 | BMC Med Genomics | pmid:20102610 |
| Sato T and Iino T | Genetic analyses of the antibiotic resistance of Bifidobacterium bifidum strain Yakult YIT 4007. | 2010 | Int. J. Food Microbiol. | pmid:20051305 |
| Prakash H et al. | Sphingosine kinase-1 (SphK-1) regulates Mycobacterium smegmatis infection in macrophages. | 2010 | PLoS ONE | pmid:20498849 |
| Barkun AN et al. | Prokinetics in acute upper GI bleeding: a meta-analysis. | 2010 | Gastrointest. Endosc. | pmid:20970794 |
| Hu L et al. | Synthesis and antibacterial activity of C-12 pyrazolinyl spiro ketolides. | 2010 | Eur J Med Chem | pmid:20970894 |
| Chen PE et al. | Rapid identification of genetic modifications in Bacillus anthracis using whole genome draft sequences generated by 454 pyrosequencing. | 2010 | PLoS ONE | pmid:20811637 |
| Sakahara S et al. | Physiological characteristics of gastric contractions and circadian gastric motility in the free-moving conscious house musk shrew (Suncus murinus). | 2010 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:20686171 |
| Di Luca MC et al. | Lysogenic transfer of mef(A) and tet(O) genes carried by Phim46.1 among group A streptococci. | 2010 | Antimicrob. Agents Chemother. | pmid:20643900 |