erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Abnormalities, Drug-Induced D000014 10 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Abscess D000038 13 associated lipids
Peritonsillar Abscess D000039 1 associated lipids
Acne Vulgaris D000152 35 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Actinomycosis, Cervicofacial D000197 1 associated lipids
Adenocarcinoma D000230 166 associated lipids
Agammaglobulinemia D000361 4 associated lipids
Airway Obstruction D000402 13 associated lipids
Alveolitis, Extrinsic Allergic D000542 6 associated lipids
Anemia, Hemolytic, Autoimmune D000744 5 associated lipids
Anemia, Hypochromic D000747 5 associated lipids
Angiomatosis D000798 1 associated lipids
Animal Diseases D000820 2 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Aortic Valve Stenosis D001024 4 associated lipids
Spider Bites D001098 1 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Asthenia D001247 5 associated lipids
Ataxia D001259 20 associated lipids
Auditory Diseases, Central D001304 2 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Bacterial Infections D001424 21 associated lipids
Bacteriuria D001437 7 associated lipids
Balanitis D001446 4 associated lipids
Bartonella Infections D001474 3 associated lipids
Bile Reflux D001655 2 associated lipids
Birth Weight D001724 23 associated lipids
Bites, Human D001734 2 associated lipids
Blepharitis D001762 4 associated lipids
Blister D001768 16 associated lipids
Body Weight D001835 333 associated lipids
Bone Resorption D001862 7 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Bradycardia D001919 13 associated lipids
Bronchiectasis D001987 7 associated lipids
Bronchiolitis D001988 6 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
Bronchopneumonia D001996 7 associated lipids
Bundle-Branch Block D002037 2 associated lipids
Bursitis D002062 3 associated lipids
Campylobacter Infections D002169 13 associated lipids
Carbuncle D002270 1 associated lipids
Cardiac Tamponade D002305 7 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Cat-Scratch Disease D002372 4 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Alexander RE and Grogan DM Long-acting erythromycins: assessing their role in treating outpatient odontogenic infections. 2009 Tex Dent J pmid:19472551
Kabir AR et al. Management of bronchiolitis without antibiotics: a multicentre randomized control trial in Bangladesh. 2009 Acta Paediatr. pmid:19572992
Ung D et al. Metabolic interactions between prokinetic agents domperidone and erythromycin: an in vitro analysis. 2009 Xenobiotica pmid:19575604
Dalisay DS et al. Absolute configuration of the alpha,omega-bifunctionalized sphingolipid leucettamol A from Leucetta microrhaphis by deconvoluted exciton coupled CD. 2009 J. Nat. Prod. pmid:19159253
Savino C et al. Investigating the structural plasticity of a cytochrome P450: three-dimensional structures of P450 EryK and binding to its physiological substrate. 2009 J. Biol. Chem. pmid:19625248
Arias CA et al. Cotransfer of antibiotic resistance genes and a hylEfm-containing virulence plasmid in Enterococcus faecium. 2009 Antimicrob. Agents Chemother. pmid:19667280
Rukayadi Y et al. In vitro activities of panduratin A against clinical Staphylococcus strains. 2009 Antimicrob. Agents Chemother. pmid:19651906
Abu-Shandi KH Determination of vancomycin in human plasma using high-performance liquid chromatography with fluorescence detection. 2009 Anal Bioanal Chem pmid:19655128
Michaud L Incision separation after eye rubbing on a postradial keratotomy cornea: a case report. 2009 Eye Contact Lens pmid:19657280
Gomes T et al. Macrolide-induced digoxin toxicity: a population-based study. 2009 Clin. Pharmacol. Ther. pmid:19606089
Feld L et al. Characterization of a small erythromycin resistance plasmid pLFE1 from the food-isolate Lactobacillus plantarum M345. 2009 Plasmid pmid:19399991
Cheng YS et al. Stress-induced cardiac insufficiency relating to abnormal leptin and FKBP12.6 is ameliorated by CPU0213, an endothelin receptor antagonist, which is not affected by the CYP3A suppressing effect of erythromycin. 2009 J. Pharm. Pharmacol. pmid:19405994
Majumdar S et al. Vitreal kinetics of quinidine in rabbits in the presence of topically coadministered P-glycoprotein substrates/modulators. 2009 Drug Metab. Dispos. pmid:19406953
Zonenschain D et al. Erythromycin- and tetracycline-resistant lactobacilli in Italian fermented dry sausages. 2009 J. Appl. Microbiol. pmid:19426258
Bostan K et al. Prevalence and antibiotic susceptibility of thermophilic Campylobacter species on beef, mutton, and chicken carcasses in Istanbul, Turkey. 2009 Microb. Drug Resist. pmid:19432522
Pinheiro S et al. Prevalence and mechanisms of erythromycin resistance in Streptococcus agalactiae from healthy pregnant women. 2009 Microb. Drug Resist. pmid:19432524
Ahmed AB et al. Strain measurement during antral contractions by ultrasound strain rate imaging: influence of erythromycin. 2009 Neurogastroenterol. Motil. pmid:18086208
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Yamaya M [Effects of macrolides in preventing influenza and airway inflammation]. 2009 Jpn J Antibiot pmid:22454856
Lin HT et al. MacB ABC transporter is a dimer whose ATPase activity and macrolide-binding capacity are regulated by the membrane fusion protein MacA. 2009 J. Biol. Chem. pmid:18955484
Crider KS et al. Antibacterial medication use during pregnancy and risk of birth defects: National Birth Defects Prevention Study. 2009 Arch Pediatr Adolesc Med pmid:19884587
Paasche SR Rhodococcus equi infection in a surgical wound. 2009 Clin Lab Sci pmid:19827407
Beliaev AM et al. Erythromycin-induced postprandial biliary colic. 2009 N. Z. Med. J. pmid:19829393
Zhang X et al. Prediction of the effect of erythromycin, diltiazem, and their metabolites, alone and in combination, on CYP3A4 inhibition. 2009 Drug Metab. Dispos. pmid:18854379
Ri E et al. [EM and EM703 suppress inflammatory cytokines formation by human respiratory epithelial cells provoked by diesel exhaust particles]. 2009 Jpn J Antibiot pmid:22452046
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Yamauchi K et al. [14-membered ring macrolides exaggerate IL-10 expression stimulated by LPS]. 2009 Jpn J Antibiot pmid:22452057
Maruyama K et al. [Analysis of the mechanism involved in the effects of erythromycin in suppressing the development of pseudomembranous colitis]. 2009 Jpn J Antibiot pmid:22452058
Zhu Q et al. Sesquiterpenoids and phenylpropanoids from pericarps of Illicium oligandrum. 2009 J. Nat. Prod. pmid:19159273
Nash KA et al. A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. 2009 Antimicrob. Agents Chemother. pmid:19171799
Renye JA and Somkuti GA Insertion of a heterologous gene construct into a non-functional ORF of the Streptococcus thermophilus chromosome. 2009 Biotechnol. Lett. pmid:19172230
Kim HC and Kang SH Total synthesis of azithromycin. 2009 Angew. Chem. Int. Ed. Engl. pmid:19173267
Kawai K et al. Serum protein binding displacement: theoretical analysis using a hypothetical radiopharmaceutical and experimental analysis with 123I-N-isopropyl-p-iodoamphetamine. 2009 Nucl. Med. Biol. pmid:19181274
Blackman Northwood J et al. Characterization of macrolide efflux pump mef subclasses detected in clinical isolates of Streptococcus pyogenes isolated between 1999 and 2005. 2009 Antimicrob. Agents Chemother. pmid:19258262
Fan Y et al. Preparation and characteristics of erythromycin microspheres for lung targeting. 2009 Drug Dev Ind Pharm pmid:19259878
Markel DC et al. Inhibitory effects of erythromycin on wear debris-induced VEGF/Flt-1 gene production and osteolysis. 2009 Inflamm. Res. pmid:19262986
Zheng J et al. Structure and function of the macrolide biosensor protein, MphR(A), with and without erythromycin. 2009 J. Mol. Biol. pmid:19265703
Zou X et al. Oxygen uptake rate optimization with nitrogen regulation for erythromycin production and scale-up from 50 L to 372 m3 scale. 2009 Bioresour. Technol. pmid:18929481
Chan JC et al. Epidemiological analysis of Streptococcus pyogenes infections in Hong Kong. 2009 Pathology pmid:20001348
Udayakumar D and Sanaullah M Campylobacter cholecystitis. 2009 Int J Med Sci pmid:19960123
Hariharan H et al. Antimicrobial drug resistance as determined by the E-test in Campylobacter jejuni, C. coli, and C. lari isolates from the ceca of broiler and layer chickens in Grenada. 2009 Comp. Immunol. Microbiol. Infect. Dis. pmid:18329712
Umehara Y et al. Campylobacter fetus meningitis in a patient with Crohn's disease. 2009 Inflamm. Bowel Dis. pmid:18798576
Accorinti M Ocular bartonellosis. 2009 Int J Med Sci pmid:19319232
Vila-Corcoles A et al. Drug-resistance in Streptococcus pneumoniae isolates among Spanish middle aged and older adults with community-acquired pneumonia. 2009 BMC Infect. Dis. pmid:19320989
Sader HS et al. Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. 2009 Antimicrob. Agents Chemother. pmid:19289528
Razzaq A et al. Erythromycin establishes early oral feeding in neonates operated for congenital intestinal atresias. 2009 Pediatr. Surg. Int. pmid:19290531
Lindqvist M et al. A clonal outbreak of methicillin-susceptible Staphylococcus aureus with concomitant resistance to erythromycin, clindamycin and tobramycin in a Swedish county. 2009 Scand. J. Infect. Dis. pmid:19294581
Sambo N et al. Effect of the aqueous extract of Psidium guajava on erythromycin-induced liver damage in rats. 2009 Niger J Physiol Sci pmid:20234760
Kumar S et al. Ligand diversity of human and chimpanzee CYP3A4: activation of human CYP3A4 by lithocholic acid results from positive selection. 2009 Drug Metab. Dispos. pmid:19299527
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Sanger GJ et al. GSK962040: a small molecule, selective motilin receptor agonist, effective as a stimulant of human and rabbit gastrointestinal motility. 2009 Neurogastroenterol. Motil. pmid:19374732
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Poeta P et al. Influence of oral hygiene in patients with fixed appliances in the oral carriage of antimicrobial-resistant Escherichia coli and Enterococcus isolates. 2009 Oral Surg Oral Med Oral Pathol Oral Radiol Endod pmid:19778742
Fan C et al. Influence of trace erythromycin and eryhthromycin-H2O on carbon and nutrients removal and on resistance selection in sequencing batch reactors (SBRs). 2009 Appl. Microbiol. Biotechnol. pmid:19727707
Seville LA et al. Distribution of tetracycline and erythromycin resistance genes among human oral and fecal metagenomic DNA. 2009 Microb. Drug Resist. pmid:19728772
Du-Cuny L et al. Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. 2009 Bioorg. Med. Chem. pmid:19734051
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Xu P et al. Synthesis and antibacterial activity of 11,12-carbamate-3-O-acyl erythromycin derivatives. 2009 J Asian Nat Prod Res pmid:20183250
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Purves GI et al. Exchange protein activated by cAMP (Epac) mediates cAMP-dependent but protein kinase A-insensitive modulation of vascular ATP-sensitive potassium channels. 2009 J. Physiol. (Lond.) pmid:19491242
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Harnden A Whooping cough. 2009 BMJ pmid:19460804
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Wu L et al. In vitro effects of erythromycin on RANKL and nuclear factor-kappa B by human TNF-alpha stimulated Jurkat cells. 2009 Int. Immunopharmacol. pmid:19500694
Takagi Y et al. Erythromycin-induced CXCR4 expression on microvascular endothelial cells. 2009 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:19502290