erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
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Authors | Title | Published | Journal | PubMed Link |
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Neri I et al. | Perianal streptococcal dermatitis in adults. | 1996 | Br. J. Dermatol. | pmid:8977685 |
Watkins VS et al. | Comparison of dirithromycin and penicillin for treatment of streptococcal pharyngitis. | 1997 | Antimicrob. Agents Chemother. | pmid:8980757 |
Fasola EL et al. | Variation in erythromycin and clindamycin susceptibilities of Streptococcus pneumoniae by four test methods. | 1997 | Antimicrob. Agents Chemother. | pmid:8980768 |
Vermeij CG et al. | Campylobacter jejuni peritonitis in a patient with liver cirrhosis. | 1996 | Eur J Gastroenterol Hepatol | pmid:8980944 |
Brenciaglia MI et al. | Inhibitory and bactericidal activity of rokitamycin against Helicobacter pylori and morphological alterations. | 1996 | J Chemother | pmid:8981182 |
Sasaki J et al. | Microbial glycosylation of macrolide antibiotics by Streptomyces hygroscopicus ATCC 31080 and distribution of a macrolide glycosyl transferase in several Streptomyces strains. | 1996 | J. Antibiot. | pmid:8982340 |
Ono T et al. | In vitro and in vivo antibacterial activities of clarithromycin. | 1996 May-Jun | Chemotherapy | pmid:8983882 |
Shortridge VD et al. | Novel mechanism of macrolide resistance in Streptococcus pneumoniae. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:8985659 |
Kodama M et al. | The value of the dehydroepiandrosterone-annexed vitamin C infusion treatment in the clinical control of chronic fatigue syndrome (CFS). I. A Pilot study of the new vitamin C infusion treatment with a volunteer CFS patient. | 1996 Nov-Dec | In Vivo | pmid:8986467 |
Kodama M et al. | The value of the dehydroepiandrosterone-annexed vitamin C infusion treatment in the clinical control of chronic fatigue syndrome (CFS). II. Characterization of CFS patients with special reference to their response to a new vitamin C infusion treatment. | 1996 Nov-Dec | In Vivo | pmid:8986468 |
Wille KK et al. | Replicate plating: does it increase reliability? | 1996 | Lett. Appl. Microbiol. | pmid:8987446 |
Johnson DM and Jones RN | Two investigational glycylcyclines, DMG-DMDOT and DMG-MINO. Antimicrobial activity studies against gram-positive species. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:8988765 |
Lakritz J et al. | Effect of treatment with erythromycin on bronchoalveolar lavage fluid cell populations in foals. | 1997 | Am. J. Vet. Res. | pmid:8989497 |
GarcÃa de Lomas J et al. | [Activity of erythromycin and clarithromicin against isolates of Streptococcus pneumoniae with decreased sensitivity to penicillin obtained from healty carriers. Spanish Collaborative Group]. | 1996 Aug-Sep | Enferm. Infecc. Microbiol. Clin. | pmid:8991436 |
Kane GC | Legionella species community-acquired pneumonia. | 1997 | Chest | pmid:8996030 |
Ross JI et al. | Minimal functional system required for expression of erythromycin resistance by msrA in Staphylococcus aureus RN4220. | 1996 | Gene | pmid:8996099 |
Yamada K et al. | Electrophysiological characterization of a motilin agonist, GM611, on rabbit duodenal smooth muscle. | 1996 | Am. J. Physiol. | pmid:8997244 |
Vanhoof R et al. | In vitro susceptibilities of 176 clinical isolates of Streptococcus pneumoniae to 11 beta-lactams, erythromycin, and tetracycline. | 1996 | Acta Clin Belg | pmid:8997755 |
Hernández JM et al. | Clinical efficacy of dirithromycin in patients with bacteremic pneumonia. | 1996 Nov-Dec | Clin Ther | pmid:9001829 |
Buche A et al. | Interaction between ATP, oleandomycin and the OleB ATP-binding cassette transporter of Streptomyces antibioticus involved in oleandomycin secretion. | 1997 | Biochem. J. | pmid:9003412 |
Cornaglia G et al. | Rapid increase of resistance to erythromycin and clindamycin in Streptococcus pyogenes in Italy, 1993-1995. The Italian Surveillance Group for Antimicrobial Resistance. | 1996 Oct-Dec | Emerging Infect. Dis. | pmid:9011381 |
Kupferman A and Leibowitz HM | Topical antibiotic therapy of staphylococcal keratitis. | 1977 | Arch. Ophthalmol. | pmid:901273 |
Goldberg MJ et al. | Effect of dirithromycin on human CYP3A in vitro and on pharmacokinetics and pharmacodynamics of terfenadine in vivo. | 1996 | J Clin Pharmacol | pmid:9013373 |
Tokinaga N et al. | Hallucinations after a therapeutic dose of benzodiazepine hypnotics with co-administration of erythromycin. | 1996 | Psychiatry Clin. Neurosci. | pmid:9014234 |
Wolfson C et al. | The Etest for antimicrobial susceptibility testing of Bartonella henselae. | 1996 | J. Antimicrob. Chemother. | pmid:9023643 |
Burkhart GA et al. | Temporal decline in filling prescriptions for terfenadine closely in time with those for either ketoconazole or erythromycin. | 1997 | Clin. Pharmacol. Ther. | pmid:9024177 |
Berg-Candolfi M and Candolfi E | Depression of the N-demethylation of erythromycin, azithromycin, clarithromycin and clindamycin in murine Toxoplasma infection. | 1996 | Int. J. Parasitol. | pmid:9024879 |
Minami T et al. | Effects of erythromycin in chronic idiopathic intestinal pseudo-obstruction. | 1996 | J. Gastroenterol. | pmid:9027652 |
Van Royen P et al. | Dirithromycin versus amoxiclav in the treatment of acute exacerbations of chronic bronchitis. | 1997 Jan-Feb | J. Int. Med. Res. | pmid:9027671 |
Cupp-Vickery JR and Poulos TL | Structure of cytochrome P450eryF: substrate, inhibitors, and model compounds bound in the active site. | 1997 | Steroids | pmid:9029724 |
Padhi ID et al. | Interaction between tacrolimus and erythromycin. | 1997 | Ther Drug Monit | pmid:9029762 |
Baumueller A et al. | Prostatic tissue and secretion concentrations of rosamicin and erythromycin. Experimental studies in the dog. | 1977 | Invest Urol | pmid:903212 |
Matera MG et al. | Pulmonary concentrations of dirithromycin and erythromycin during acute exacerbation of mild chronic obstructive pulmonary disease. | 1997 | Eur. Respir. J. | pmid:9032500 |
Caboche M | Methionine metabolism in BHK cells: the regulation of methionine adenosyltransferase. | 1977 | J. Cell. Physiol. | pmid:903381 |
Kim TH et al. | Pseudo-Kaposi's sarcoma associated with acquired arteriovenous fistula. | 1997 | J. Dermatol. | pmid:9046737 |
Pieper R et al. | Purification and characterization of bimodular and trimodular derivatives of the erythromycin polyketide synthase. | 1997 | Biochemistry | pmid:9048569 |
Asai T | Erythromycin and motilin as gastrointestinal prokinetic agents. | 1997 | Eur J Anaesthesiol | pmid:9049551 |
Petersen K et al. | The effect of erythromycin on resolution of symptoms among adults with pharyngitis not caused by group A streptococcus. | 1997 | J Gen Intern Med | pmid:9051558 |
Johnsson H and Niklasson PM | Effects of some antibiotics of platelet function in vitro and in vivo. | 1977 | Thromb. Res. | pmid:905975 |
Yagiela JA | Prophylactic antibiotics: cardiac and prosthetic considerations. | 1995 | J Calif Dent Assoc | pmid:9063197 |
GarcÃa-de-Lomas J et al. | Antimicrobial susceptibility of Streptococcus pneumoniae isolated from pediatric carriers in Spain. | 1997 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9063666 |
Weiss I et al. | Serotyping and susceptibility to macrolides and other antimicrobial drugs of Streptococcus pyogenes isolated from patients with invasive diseases in southern Israel. | 1997 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9063669 |
Matsuoka M et al. | A dyadic plasmid that shows MLS and PMS resistance in Staphylococcus aureus. | 1997 | FEMS Microbiol. Lett. | pmid:9066116 |
Furuno T et al. | The role of neutrophil elastase in human pulmonary artery endothelial cell injury. | 1997 | Int. Arch. Allergy Immunol. | pmid:9066513 |
Moutard I et al. | In vitro interaction between dirithromycin or its metabolite, erythromycylamine, and oxidative polymorphonuclear metabolism. | 1997 | J. Antibiot. | pmid:9066766 |
Watkins VS et al. | Drug interactions of macrolides: emphasis on dirithromycin. | 1997 | Ann Pharmacother | pmid:9066944 |
Chu A et al. | The comparative efficacy of benzoyl peroxide 5%/erythromycin 3% gel and erythromycin 4%/zinc 1.2% solution in the treatment of acne vulgaris. | 1997 | Br. J. Dermatol. | pmid:9068739 |
Renneberg J et al. | Antimicrobial susceptibility of 278 streptococcal blood isolates to seven antimicrobial agents. | 1997 | J. Antimicrob. Chemother. | pmid:9069532 |
Matsumoto K et al. | [Effects of erythromycin on H2O2 generation by neutrophils]. | 1997 | Nihon Kyobu Shikkan Gakkai Zasshi | pmid:9071149 |
Hueston WJ | Antibiotics: neither cost effective nor 'cough' effective. | 1997 | J Fam Pract | pmid:9071245 |