erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Tomomasa T et al. | Gastrointestinal sounds and migrating motor complex in fasted humans. | 1999 | Am. J. Gastroenterol. | pmid:10022632 |
Carbonell N et al. | Erythromycin infusion prior to endoscopy for acute upper gastrointestinal bleeding: a randomized, controlled, double-blind trial. | 2006 | Am. J. Gastroenterol. | pmid:16771939 |
Glupczynski Y and Burette A | Failure of azythromycin to eradicate Campylobacter pylori from the stomach because of acquired resistance during treatment. | 1990 | Am. J. Gastroenterol. | pmid:2153337 |
Maganti K et al. | Oral erythromycin and symptomatic relief of gastroparesis: a systematic review. | 2003 | Am. J. Gastroenterol. | pmid:12591038 |
Janssen P et al. | The relation between symptom improvement and gastric emptying in the treatment of diabetic and idiopathic gastroparesis. | 2013 | Am. J. Gastroenterol. | pmid:24005344 |
Chang AD et al. | Bacillary angiomatosis associated with extensive esophageal polyposis: a new mucocutaneous manifestation of acquired immunodeficiency disease (AIDS). | 1996 | Am. J. Gastroenterol. | pmid:8855753 |
DiBaise JK et al. | Effects of low doses of erythromycin on the 13C Spirulina platensis gastric emptying breath test and electrogastrogram: a controlled study in healthy volunteers. | 2001 | Am. J. Gastroenterol. | pmid:11467630 |
DITTLER EL | Upper abdominal pain and intrahepatic cholestasis as manifestations of sensitivity to ilosone. | 1962 | Am. J. Gastroenterol. | pmid:14028076 |
VIRANUVATTI V and BISESHURARIT P | Clinical trial of erythromycin in amebic liver abscess. | 1955 | Am. J. Gastroenterol. | pmid:13228406 |
Jones KL et al. | The effect of erythromycin on gastric emptying is modified by physiological changes in the blood glucose concentration. | 1999 | Am. J. Gastroenterol. | pmid:10445530 |
Rayner CK et al. | The stimulation of antral motility by erythromycin is attenuated by hyperglycemia. | 2000 | Am. J. Gastroenterol. | pmid:11007223 |
Bachman BA et al. | Erythromycin ethylsuccinate-induced cholestasis. | 1982 | Am. J. Gastroenterol. | pmid:6979924 |
Richards RD et al. | The treatment of idiopathic and diabetic gastroparesis with acute intravenous and chronic oral erythromycin. | 1993 | Am. J. Gastroenterol. | pmid:8424421 |
Bonacini M et al. | Effect of intravenous erythromycin on postoperative ileus. | 1993 | Am. J. Gastroenterol. | pmid:8424422 |
Weber FH et al. | Erythromycin: a motilin agonist and gastrointestinal prokinetic agent. | 1993 | Am. J. Gastroenterol. | pmid:8470625 |
Ruffin WK | Erythromycin: a postoperative jumpstart? | 1994 | Am. J. Gastroenterol. | pmid:7909647 |
CURTIN JA | THE EFFECT OF ANTIBIOTICS UPON THE GASTROINTESTINAL TRACT. | 1964 | Am. J. Gastroenterol. | pmid:14206198 |
McNulty CA | The treatment of Campylobacter-associated gastritis. | 1987 | Am. J. Gastroenterol. | pmid:3493685 |
Koutsoumbi P et al. | The effect of erythromycin on human esophageal motility is mediated by serotonin receptors. | 2000 | Am. J. Gastroenterol. | pmid:11151866 |
Portincasa P et al. | The effect of acute oral erythromycin on gallbladder motility and on upper gastrointestinal symptoms in gastrectomized patients with and without gallstones: a randomized, placebo-controlled ultrasonographic study. | 2000 | Am. J. Gastroenterol. | pmid:11151875 |
Carmagnola S et al. | Mechanoreceptors of the proximal stomach and perception of gastric distension. | 2005 | Am. J. Gastroenterol. | pmid:16086705 |
Moussa F et al. | Erythromycin eye ointment: effect on gastrointestinal motility. | 2000 | Am. J. Gastroenterol. | pmid:10710093 |
Nolan CM et al. | Campylobacter jejuni enteritis: efficacy of antimicrobial and antimotility drugs. | 1983 | Am. J. Gastroenterol. | pmid:6624735 |
Masclee AA et al. | Effect of erythromycin on gallbladder emptying in patients with antrectomy or truncal vagotomy. | 1995 | Am. J. Gastroenterol. | pmid:7771433 |
Laine L and Jensen DM | Management of patients with ulcer bleeding. | 2012 | Am. J. Gastroenterol. | pmid:22310222 |
Slotkin RI et al. | The effect of antibiotics on Mycoplasma pneumoniae in vitro and in vivo. | 1967 | Am. J. Epidemiol. | pmid:5006447 |
Heggie AD et al. | Topical sulfacetamide vs oral erythromycin for neonatal chlamydial conjunctivitis. | 1985 | Am. J. Dis. Child. | pmid:3890519 |
Rodriguez WJ et al. | Erythromycin-sulfisoxazole vs amoxicillin in the treatment of acute otitis media in children. A double-blind, multiple-dose comparative study. | 1985 | Am. J. Dis. Child. | pmid:3895889 |
Howie VM and Ploussard JH | Compliance dose-response relationships in streptococcal pharyngitis. | 1972 | Am. J. Dis. Child. | pmid:4622022 |
Bass JW et al. | Antimicrobials in the treatment of acute otitis media. A second clinical trial. | 1973 | Am. J. Dis. Child. | pmid:4632555 |
Maruyama S et al. | Sensitivity of group A streptococci to antibiotics. Prevalence of resistance to erythromycin in Japan. | 1979 | Am. J. Dis. Child. | pmid:389035 |
Derrick CW and Dillon HC | Streptococcal pharyngitis therapy. A comparison of two erythromycin formulations. | 1979 | Am. J. Dis. Child. | pmid:389036 |
Pai CH et al. | Erythromycin in treatment of Campylobacter enteritis in children. | 1983 | Am. J. Dis. Child. | pmid:6600579 |
Disney FA and Pichichero ME | Treatment of Staphylococcus aureus infections in children in office practice. | 1983 | Am. J. Dis. Child. | pmid:6600877 |
Wannamaker LW | Perplexity and precision in the diagnosis of streptococcal pharyngitis. | 1972 | Am. J. Dis. Child. | pmid:5056872 |
Demidovich CW et al. | Impetigo. Current etiology and comparison of penicillin, erythromycin, and cephalexin therapies. | 1990 | Am. J. Dis. Child. | pmid:2244610 |
Esterly NB et al. | Impetigo. | 1991 | Am. J. Dis. Child. | pmid:1899777 |
Hughes WT and Collier RN | Streptococcal pharyngitis. Evaluation of erythromycin, erythromycin-sulfas, and sulfamethoxazole (possible antagonism between erythromycin and sulfas). | 1969 | Am. J. Dis. Child. | pmid:5348368 |
Dillon HC and Ware JC | Sources and susceptibilities of staphylococci isolated from children. A seven-year survey. | 1981 | Am. J. Dis. Child. | pmid:7234768 |
Barton LL and Friedman AD | Etiology and therapy of impetigo: reconsidered. | 1990 | Am. J. Dis. Child. | pmid:2305731 |
Phair JP et al. | Penicillin phenoxymethyl. Use in rheumatic fever prophylaxis. | 1973 | Am. J. Dis. Child. | pmid:4198746 |
Harrison HS et al. | Congenital laryngeal cleft: report of a case. A comparison with other types of tracheo-esophageal communication. | 1965 | Am. J. Dis. Child. | pmid:5846694 |
Garber MJ | Erythromycin-resistant group A streptococci. | 1981 | Am. J. Dis. Child. | pmid:7015829 |
Khuri-Bulos N et al. | Bacteroides brain abscess treated with clindamycin. | 1973 | Am. J. Dis. Child. | pmid:4723176 |
Hughes WT and Wan RT | Impetigo contagiosa: etiology, complications, and comparison of therapeutic effectiveness of erythromycin and antibiotic ointment. | 1967 | Am. J. Dis. Child. | pmid:4290285 |
Breese BB et al. | B-hemolytic streptococcal illness. A comparison of the effectiveness of penicillin G, triacetyloleandomycin, and erythromycin estolate. | 1966 | Am. J. Dis. Child. | pmid:5322797 |
Wittler RR et al. | Penicillin tolerance and erythromycin resistance of group A beta-hemolytic streptococci in Hawaii and the Philippines. | 1990 | Am. J. Dis. Child. | pmid:2184661 |
Halsey NA et al. | Nosocomial pertussis: a failure of erythromycin treatment and prophylaxis. | 1980 | Am. J. Dis. Child. | pmid:7377164 |
HALTALIN KC and NELSON JD | HAND-FOOT SYNDROME DUE TO STREPTOCOCCAL INFECTION. | 1965 | Am. J. Dis. Child. | pmid:14237416 |
Bruhn FW | Lyme disease. | 1984 | Am. J. Dis. Child. | pmid:6711502 |