erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yamaguchi K et al. | [Legionella pneumonia--epidemiology, clinical characteristics and development of diagnosis]. | 1998 | Nippon Rinsho | pmid:9796341 |
| Piccolomini R et al. | Bacteriostatic and bactericidal in vitro activities of clarithromycin and erythromycin against periodontopathic Actinobacillus actinomycetemcomitans. | 1998 | Antimicrob. Agents Chemother. | pmid:9797240 |
| Tunney MM et al. | Antimicrobial susceptibility of bacteria isolated from orthopedic implants following revision hip surgery. | 1998 | Antimicrob. Agents Chemother. | pmid:9797241 |
| Nicola FG et al. | Characterization of erythromycin-resistant isolates of Staphylococcus aureus recovered in the United States from 1958 through 1969. | 1998 | Antimicrob. Agents Chemother. | pmid:9797248 |
| Kneen R et al. | Penicillin vs. erythromycin in the treatment of diphtheria. | 1998 | Clin. Infect. Dis. | pmid:9798043 |
| Harris JA et al. | Safety and efficacy of azithromycin in the treatment of community-acquired pneumonia in children. | 1998 | Pediatr. Infect. Dis. J. | pmid:9802626 |
| Levin S and Jupa JE | Principles of antibiotic usage in obstetrics and gynecology. | 1976 | Obstet Gynecol Annu | pmid:980275 |
| Kisch AL | Principles of the antimicrobial therapy of head and neck infections. | 1976 | Otolaryngol. Clin. North Am. | pmid:980506 |
| Kondo M et al. | Erythromycin inhibits ATP-induced intracellular calcium responses in bovine tracheal epithelial cells. | 1998 | Am. J. Respir. Cell Mol. Biol. | pmid:9806744 |
| Sanchez R | A medium-copy-number plasmid for insertional mutagenesis of Streptococcus mutans. | 1998 | Plasmid | pmid:9806863 |
| Yamazaki H and Shimada T | Comparative studies of in vitro inhibition of cytochrome P450 3A4-dependent testosterone 6beta-hydroxylation by roxithromycin and its metabolites, troleandomycin, and erythromycin. | 1998 | Drug Metab. Dispos. | pmid:9806945 |
| Champney WS and Tober CL | Inhibition of translation and 50S ribosomal subunit formation in Staphylococcus aureus cells by 11 different ketolide antibiotics. | 1998 | Curr. Microbiol. | pmid:9806981 |
| Nakazawa Y et al. | Relationship between in vivo FK506 clearance and in vitro 13-demethylation activity in living-related liver transplantation. | 1998 | Transplantation | pmid:9808496 |
| Tanaka T et al. | Effects of EM574 and cisapride on gastric contractile and emptying activity in normal and drug-induced gastroparesis in dogs. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9808701 |
| Taniguchi K et al. | Identification of Escherichia coli clinical isolates producing macrolide 2'-phosphotransferase by a highly sensitive detection method. | 1998 | FEMS Microbiol. Lett. | pmid:9809420 |
| Villar D et al. | Novobiocin inhibits both UDP-glucuronosyltransferase and cytochrome P450-mediated enzyme activities in pig liver microsomes. | 1998 | Vet. Res. Commun. | pmid:9810637 |
| Kaufhold A and Klein R | Species identification and antibiotic susceptibility of enterococci isolated from clinical specimens of hospitalized patients. | 1995 | Zentralbl. Bakteriol. | pmid:9810675 |
| Nizami SQ and Farooqui BJ | Cholera in children in Karachi from 1990 through 1995: a study of cases admitted to a tertiary care hospital. | 1998 | J Pak Med Assoc | pmid:9813989 |
| Champney WS and Burdine R | Macrolide antibiotic inhibition of translation and 50S ribosomal subunit assembly in methicillin-resistant Staphylococcus aureus cells. | 1998 | Microb. Drug Resist. | pmid:9818968 |
| Udo EE and Jacob LE | Conjugative transfer of high-level mupirocin resistance and the mobilization of non-conjugative plasmids in Staphylococcus aureus. | 1998 | Microb. Drug Resist. | pmid:9818970 |