Liu Z et al. |
Metabolism studies of the anti-tumor agent maytansine and its analog ansamitocin P-3 using liquid chromatography/tandem mass spectrometry. |
2005 |
J Mass Spectrom |
pmid:15674857
|
Lu C et al. |
A novel amide N-glycoside of ansamitocins from Actinosynnema pretiosum. |
2004 |
J. Antibiot. |
pmid:15303496
|
Liu Z et al. |
An API LC/MS/MS quantitation method for ansamitocin P-3 (AP3) and its preclinical pharmacokinetics. |
2004 |
J Pharm Biomed Anal |
pmid:15533675
|
Spiteller P et al. |
The post-polyketide synthase modification steps in the biosynthesis of the antitumor agent ansamitocin by Actinosynnema pretiosum. |
2003 |
J. Am. Chem. Soc. |
pmid:14624546
|
Carroll BJ et al. |
Identification of a set of genes involved in the formation of the substrate for the incorporation of the unusual "glycolate" chain extension unit in ansamitocin biosynthesis. |
2002 |
J. Am. Chem. Soc. |
pmid:11960423
|
Yu TW et al. |
The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum. |
2002 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:12060743
|
Moss SJ et al. |
Identification of asm19 as an acyltransferase attaching the biologically essential ester side chain of ansamitocins using N-desmethyl-4,5-desepoxymaytansinol, not maytansinol, as its substrate. |
2002 |
J. Am. Chem. Soc. |
pmid:12047169
|
Havens CG et al. |
Cellular effects of leishmanial tubulin inhibitors on L. donovani. |
2000 |
Mol. Biochem. Parasitol. |
pmid:11071278
|
Liu C et al. |
Eradication of large colon tumor xenografts by targeted delivery of maytansinoids. |
1996 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:8710920
|
Okamoto K et al. |
Therapeutic effect of ansamitocin targeted to tumor by a bispecific monoclonal antibody. |
1992 |
Jpn. J. Cancer Res. |
pmid:1517150
|