Ansamitocin P-3

Ansamitocin P-3 is a lipid of Polyketides (PK) class.

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Current reference collection contains 418 references associated with Ansamitocin P-3 in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Liu Z et al. Metabolism studies of the anti-tumor agent maytansine and its analog ansamitocin P-3 using liquid chromatography/tandem mass spectrometry. 2005 J Mass Spectrom pmid:15674857
Lu C et al. A novel amide N-glycoside of ansamitocins from Actinosynnema pretiosum. 2004 J. Antibiot. pmid:15303496
Liu Z et al. An API LC/MS/MS quantitation method for ansamitocin P-3 (AP3) and its preclinical pharmacokinetics. 2004 J Pharm Biomed Anal pmid:15533675
Spiteller P et al. The post-polyketide synthase modification steps in the biosynthesis of the antitumor agent ansamitocin by Actinosynnema pretiosum. 2003 J. Am. Chem. Soc. pmid:14624546
Carroll BJ et al. Identification of a set of genes involved in the formation of the substrate for the incorporation of the unusual "glycolate" chain extension unit in ansamitocin biosynthesis. 2002 J. Am. Chem. Soc. pmid:11960423
Yu TW et al. The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum. 2002 Proc. Natl. Acad. Sci. U.S.A. pmid:12060743
Moss SJ et al. Identification of asm19 as an acyltransferase attaching the biologically essential ester side chain of ansamitocins using N-desmethyl-4,5-desepoxymaytansinol, not maytansinol, as its substrate. 2002 J. Am. Chem. Soc. pmid:12047169
Havens CG et al. Cellular effects of leishmanial tubulin inhibitors on L. donovani. 2000 Mol. Biochem. Parasitol. pmid:11071278
Liu C et al. Eradication of large colon tumor xenografts by targeted delivery of maytansinoids. 1996 Proc. Natl. Acad. Sci. U.S.A. pmid:8710920
Okamoto K et al. Therapeutic effect of ansamitocin targeted to tumor by a bispecific monoclonal antibody. 1992 Jpn. J. Cancer Res. pmid:1517150

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