oxytetracycline is a lipid of Polyketides (PK) class. Oxytetracycline is associated with abnormalities such as Infection, X-linked centronuclear myopathy, Bacterial Infections, Heart failure and Onchocerciasis. The involved functions are known as Anabolism, physiological aspects, Transcription, Genetic, Fermentation and Transcriptional Activation. Oxytetracycline often locates in Chromosomes, Flank (surface region), Entire bony skeleton, Bone Marrow and Body tissue. The associated genes with oxytetracycline are Polypeptides, Homologous Gene, Gene Clusters, Locus and CYCS gene. The related lipids are LH 1 and Lipid Peroxides. The related experimental models are Disease model.
To understand associated biological information of oxytetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
oxytetracycline is suspected in Infection, Helminthiasis, Nodule, Bacterial Infections, Yeast infection, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with oxytetracycline
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Disease model are used in the study 'A molecular ecological approach to the detection and designation of the etiological agents of a model polymicrobial disease.' (Antiabong JF et al., 2013).
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Authors | Title | Published | Journal | PubMed Link |
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Maia PP et al. | Simultaneous determination of streptomycin and oxytetracycline in agricultural antimicrobials by CZE after an experimental design. | 2007 | J Pharm Biomed Anal | pmid:16930914 |
Romero-González R et al. | Simultaneous determination of selected veterinary antibiotics in gilthead seabream (Sparus Aurata) by liquid chromatography-mass spectrometry. | 2007 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:17644050 |
Puhó EH et al. | Drug treatment during pregnancy and isolated orofacial clefts in hungary. | 2007 | Cleft Palate Craniofac. J. | pmid:17328645 |
Kong WD et al. | Uptake of oxytetracycline and its phytotoxicity to alfalfa (Medicago sativa L.). | 2007 | Environ. Pollut. | pmid:17029682 |
Agersø Y and Petersen A | The tetracycline resistance determinant Tet 39 and the sulphonamide resistance gene sulII are common among resistant Acinetobacter spp. isolated from integrated fish farms in Thailand. | 2007 | J. Antimicrob. Chemother. | pmid:17095527 |
Blackwell PA et al. | The dissipation and transport of veterinary antibiotics in a sandy loam soil. | 2007 | Chemosphere | pmid:17204303 |
Akinbowale OL et al. | Diversity of tetracycline resistance genes in bacteria from aquaculture sources in Australia. | 2007 | J. Appl. Microbiol. | pmid:17953612 |
Toutain PL et al. | AUC/MIC: a PK/PD index for antibiotics with a time dimension or simply a dimensionless scoring factor? | 2007 | J. Antimicrob. Chemother. | pmid:17932075 |
Tan X et al. | Persistence of oxytetracycline residues in milk after the intrauterine treatment of lactating cows for endometritis. | 2007 | Vet. Rec. | pmid:17965369 |
Schrickx J and Fink-Gremmels J | P-glycoprotein-mediated transport of oxytetracycline in the Caco-2 cell model. | 2007 | J. Vet. Pharmacol. Ther. | pmid:17217397 |
Chandler HL et al. | The role of the slug transcription factor in cell migration during corneal re-epithelialization in the dog. | 2007 | Exp. Eye Res. | pmid:17196588 |
Nfon CK et al. | Lack of resistance after re-exposure of cattle cured of Onchocerca ochengi infection with oxytetracycline. | 2007 | Am. J. Trop. Med. Hyg. | pmid:17255232 |
Smyrniotakis CG and Archontaki HA | C(18) columns for the simultaneous determination of oxytetracycline and its related substances by reversed-phase high performance liquid chromatography and UV detection. | 2007 | J Pharm Biomed Anal | pmid:16989968 |
Miller RA et al. | Determination of oxytetracycline levels in rainbow trout serum on a biphenyl column using high-performance liquid chromatography. | 2007 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:17301001 |
Brambilla G et al. | Oxytetracycline as environmental contaminant in arable lands. | 2007 | Anal. Chim. Acta | pmid:17386731 |
Metzner M et al. | Effect of infusion of 60 mg/kg oxytetracycline on forelimb flexor tendon contracture in calves. | 2007 | Vet. Rec. | pmid:17277302 |
Handolin L et al. | The effect of low-intensity pulsed ultrasound on bone healing in SR-PLLA rod fixed experimental distal femur osteotomy in rat. | 2007 | J Mater Sci Mater Med | pmid:17277987 |
Kim H et al. | Reverse micelle-based microencapsulation of oxytetracycline hydrochloride into poly-d,l-lactide-co-glycolide microspheres. | 2007 | Drug Deliv | pmid:17364873 |
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Cho KY et al. | Successful combined treatment with total parenteral nutrition fluid extravasation injuries in preterm infants. | 2007 | J. Korean Med. Sci. | pmid:17596679 |
Alippi AM et al. | Evidence for plasmid-mediated tetracycline resistance in Paenibacillus larvae, the causal agent of American Foulbrood (AFB) disease in honeybees. | 2007 | Vet. Microbiol. | pmid:17601687 |
Ferreira CS et al. | Acute toxicity of oxytetracycline and florfenicol to the microalgae Tetraselmis chuii and to the crustacean Artemia parthenogenetica. | 2007 | Ecotoxicol. Environ. Saf. | pmid:17418415 |
Bakke-McKellep AM et al. | Effects of dietary soyabean meal, inulin and oxytetracycline on intestinal microbiota and epithelial cell stress, apoptosis and proliferation in the teleost Atlantic salmon (Salmo salar L.). | 2007 | Br. J. Nutr. | pmid:17349083 |
Schneider MJ et al. | Simultaneous multiresidue determination of tetracyclines and fluoroquinolones in catfish muscle using high performance liquid chromatography with fluorescence detection. | 2007 | Anal. Chim. Acta | pmid:17386722 |
Zhang W et al. | Investigation of early tailoring reactions in the oxytetracycline biosynthetic pathway. | 2007 | J. Biol. Chem. | pmid:17631493 |
Olmez SS et al. | Chitosan and alginate scaffolds for bone tissue regeneration. | 2007 | Pharmazie | pmid:17663189 |
Starke A et al. | Efficacy of intrapalpebral and intramuscular application of oxytetracycline in a natural outbreak of infectious bovine kertoconjunctivitis (IBK) in calves. | 2007 | DTW. Dtsch. Tierarztl. Wochenschr. | pmid:17642322 |
Ferguson EG | Changes in withdrawal periods. | 2007 | Vet. Rec. | pmid:17617549 |
RodrÃguez C et al. | Diversity and antimicrobial susceptibility of oxytetracycline-resistant isolates of Stenotrophomonas sp. and Serratia sp. associated with Costa Rican crops. | 2007 | J. Appl. Microbiol. | pmid:18045439 |
Dang H et al. | Molecular determination of oxytetracycline-resistant bacteria and their resistance genes from mariculture environments of China. | 2007 | J. Appl. Microbiol. | pmid:18045442 |
Kasimanickam R et al. | A field study of the effects of a monovalent Leptospira borgpetersenii serovar Hardjo strain hardjobovis vaccine administered with oxytetracycline on reproductive performance in beef cattle. | 2007 | J. Am. Vet. Med. Assoc. | pmid:18052809 |
Beltran-Alvarez P et al. | Dissecting the component reactions catalyzed by the actinorhodin minimal polyketide synthase. | 2007 | Biochemistry | pmid:18034463 |
Vega D et al. | Voltammetry and amperometric detection of tetracyclines at multi-wall carbon nanotube modified electrodes. | 2007 | Anal Bioanal Chem | pmid:17671781 |
Wabacha JK et al. | Atypical dermatophilosis of sheep in Kenya. | 2007 | J S Afr Vet Assoc | pmid:18237045 |
Nolan MW et al. | Pharmacokinetics of oxytetracycline in the American horseshoe crab, Limulus polyphemus. | 2007 | J. Vet. Pharmacol. Ther. | pmid:17803738 |
Mestorino N et al. | Pharmacokinetics and tissue residues of an oxytetracycline/diclofenac combination in cattle. | 2007 | Rev. - Off. Int. Epizoot. | pmid:18293616 |
Arikan OA et al. | Composting rapidly reduces levels of extractable oxytetracycline in manure from therapeutically treated beef calves. | 2007 | Bioresour. Technol. | pmid:16364634 |
Ebrahimi A et al. | In vitro efficacy for some local antimicrobial products against E. coli K12. | 2007 | Pak. J. Biol. Sci. | pmid:19093536 |
Altiparmak UE et al. | Postoperative endophthalmitis caused by Bacillus cereus and Chlamydia trachomatis. | 2007 | J Cataract Refract Surg | pmid:17586388 |
Kowalski C et al. | Determination of oxytetracycline in biological matrix. | 2007 May-Jun | Acta Pol Pharm | pmid:17695152 |
Gotze MM et al. | [Effects of the oxitetracycline in the increase of the packed cell volume of cows milk jugs during outbreak of bovine anaplasmosis]. | 2008 | Rev Bras Parasitol Vet | pmid:20059824 |
Gallina G et al. | Acute toxicity evaluation of four antibacterials with Daphnia magna. | 2008 | Vet. Res. Commun. | pmid:18688742 |
Mohan K et al. | Transmission of Pseudomonas aeruginosa epidemic strain from a patient with cystic fibrosis to a pet cat. | 2008 | Thorax | pmid:18728207 |
Giadinis ND et al. | Mortality in adult goats attributed to Mycoplasma capricolum subspecies capricolum. | 2008 | Vet. Rec. | pmid:18757908 |
Niazi JH et al. | ssDNA aptamers that selectively bind oxytetracycline. | 2008 | Bioorg. Med. Chem. | pmid:17988875 |
MartÃnez MF et al. | Intraglandular injection of antibiotics for the treatment of vesicular adenitis in bulls. | 2008 | Anim. Reprod. Sci. | pmid:17399921 |
Wang L et al. | Determination of oxytetracycline, tetracycline and chloramphenicol antibiotics in animal feeds using subcritical water extraction and high performance liquid chromatography. | 2008 | Anal. Chim. Acta | pmid:18539174 |
Poapolathep A et al. | Distribution and residue depletion of oxytetracycline in giant freshwater prawn (Macrobrachium rosenbergii). | 2008 | J. Food Prot. | pmid:18468050 |
Ibañez GA | Partial least-squares analysis of time decay data for Eu(III)-tetracycline complexes: simultaneous luminescent determination of tetracycline and oxytetracycline in bovine serum. | 2008 | Talanta | pmid:18585179 |
Hargrave BT et al. | A micro-dilution method for detecting oxytetracycline-resistant bacteria in marine sediments from salmon and mussel aquaculture sites and an urbanized harbour in Atlantic Canada. | 2008 | Mar. Pollut. Bull. | pmid:18589456 |
Nandi SK et al. | Efficacy of nano-hydroxyapatite prepared by an aqueous solution combustion technique in healing bone defects of goat. | 2008 | J. Vet. Sci. | pmid:18487940 |
Engemann CA et al. | Fate of tetracycline resistance genes in aquatic systems: migration from the water column to peripheral biofilms. | 2008 | Environ. Sci. Technol. | pmid:18754359 |
Knapp CW et al. | Indirect evidence of transposon-mediated selection of antibiotic resistance genes in aquatic systems at low-level oxytetracycline exposures. | 2008 | Environ. Sci. Technol. | pmid:18754392 |
Speybroeck N et al. | Titrating Theileria parva: single stocks against combination of stocks. | 2008 | Exp. Parasitol. | pmid:18155195 |
Jiao S et al. | Aqueous oxytetracycline degradation and the toxicity change of degradation compounds in photoirradiation process. | 2008 | J Environ Sci (China) | pmid:18814575 |
Grbolar A et al. | Bronchopericardial fistula, an unusual complication of oxytetracycline sclerosis therapy. | 2008 | Interact Cardiovasc Thorac Surg | pmid:18073228 |
Li D et al. | Determination and fate of oxytetracycline and related compounds in oxytetracycline production wastewater and the receiving river. | 2008 | Environ. Toxicol. Chem. | pmid:18092864 |
Fernández-Palazzi F et al. | Chemical synoviorthesis with oxytetracycline clorhydrate (Emicine) in recurrent haemarthrosis. | 2008 | Haemophilia | pmid:18005152 |
Wang Q and Yates SR | Laboratory study of oxytetracycline degradation kinetics in animal manure and soil. | 2008 | J. Agric. Food Chem. | pmid:18257526 |
Carrasco-Pancorbo A et al. | Reversed-phase high-performance liquid chromatography coupled to ultraviolet and electrospray time-of-flight mass spectrometry on-line detection for the separation of eight tetracyclines in honey samples. | 2008 | J Chromatogr A | pmid:18501371 |
Fletouris DJ and Papapanagiotou EP | A new liquid chromatographic method for routine determination of oxytetracycline marker residue in the edible tissues of farm animals. | 2008 | Anal Bioanal Chem | pmid:18197400 |
Mäkelä E et al. | Fixation of experimental osteotomies with bioabsorbable SR-polylactide-polyglycolide (80/20) polymeric rods. | 2008 | J Mater Sci Mater Med | pmid:17701306 |
Injac R et al. | Optimal conditions for determination of zinc bacitracin, polymyxin B, oxytetracycline and sulfacetamide in animal feed by micellar electrokinetic capillary chromatography. | 2008 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:18348041 |
Li K et al. | Ozonation of oxytetracycline and toxicological assessment of its oxidation by-products. | 2008 | Chemosphere | pmid:18355893 |
Heepngoen P et al. | Genetic and physiological characterization of oxytetracycline-resistant bacteria from giant prawn farms. | 2008 | J. Microbiol. Biotechnol. | pmid:18309262 |
Liu Z et al. | [Disruption of zwf2 gene to improve oxytetraclyline biosynthesis in Streptomyces rimosus M4018]. | 2008 | Wei Sheng Wu Xue Bao | pmid:18338571 |
Gai JJ and Marks SL | Salmon poisoning disease in two Malayan sun bears. | 2008 | J. Am. Vet. Med. Assoc. | pmid:18279100 |
Hassani M et al. | Thermostability of oxytetracycline, tetracycline, and doxycycline at ultrahigh temperatures. | 2008 | J. Agric. Food Chem. | pmid:18373348 |
Kanda M et al. | [Rapid determination of residues of 4 tetracyclines in meat by a microbiological screening, HPLC and LC/MS/MS]. | 2008 | Shokuhin Eiseigaku Zasshi | pmid:18344657 |
Dahiya S and Tyagi L | Preparation and evaluation of oxytetracycline hydrochloride microbeads for delayed release. | 2008 | Pak J Pharm Sci | pmid:18390438 |
Kaneene JB et al. | Changes in tetracycline susceptibility of enteric bacteria following switching to nonmedicated milk replacer for dairy calves. | 2008 | J. Clin. Microbiol. | pmid:18417664 |
Li J et al. | Determination of tetracyclines residues in honey by on-line solid-phase extraction high-performance liquid chromatography. | 2008 | Talanta | pmid:18585209 |
Fletouris DJ et al. | Liquid chromatographic determination and depletion profile of oxytetracycline in milk after repeated intramuscular administration in sheep. | 2008 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:18993118 |
Nishikawa A and Taguchi K | Healing of digital dermatitis after a single treatment with topical oxytetracycline in 89 dairy cows. | 2008 | Vet. Rec. | pmid:18997188 |
Rosenthal AK et al. | Feasibility of a tetracycline-binding method for detecting synovial fluid basic calcium phosphate crystals. | 2008 | Arthritis Rheum. | pmid:18821676 |
Carrasquillo AJ et al. | Sorption of ciprofloxacin and oxytetracycline zwitterions to soils and soil minerals: influence of compound structure. | 2008 | Environ. Sci. Technol. | pmid:18983086 |
Poapolathep A et al. | Muscle tissue kinetics of oxytetracycline following intramuscular and oral administration at two dosages to giant freshwater shrimp (Macrobrachium rosenbergii). | 2008 | J. Vet. Pharmacol. Ther. | pmid:19000273 |
Navarrete P et al. | Oxytetracycline treatment reduces bacterial diversity of intestinal microbiota of Atlantic salmon. | 2008 | J. Aquat. Anim. Health | pmid:18942594 |
Snyman MG et al. | Is the current dose of a conventional oxytetracycline formulation adequate for the management of infections in sheep? | 2008 | J S Afr Vet Assoc | pmid:19496316 |
Tiwari HK and Tiwari JG | Studies on the residues of terramycin and furazolidone in broiler meat--a public health concern. | 2008 Jan-Mar | Indian J Public Health | pmid:18700719 |
Frazer ML | Lawsonia intracellularis infection in horses: 2005-2007. | 2008 Sep-Oct | J. Vet. Intern. Med. | pmid:18681919 |
Kaiser T et al. | Tissue distribution of dexamethasone in canine ocular compartments following topical application of dexamethasone-21-isonicotinate and oxytetracycline HCl. | 2008 Sep-Oct | Vet Ophthalmol | pmid:19046294 |
Yang Q et al. | Influence of oxytetracycline on the structure and activity of microbial community in wheat rhizosphere soil. | 2009 | J Environ Sci (China) | pmid:19862962 |
Hakuta T et al. | Practical method for the detection of tetracyclines in honey by HPLC and derivative UV-Vis spectra. | 2009 | Anal Sci | pmid:19745545 |
Simon J et al. | Growth and mortality of European glass eel Anguilla anguilla marked with oxytetracycline and alizarin red. | 2009 | J. Fish Biol. | pmid:20735541 |
Byrne-Bailey KG et al. | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. | 2009 | Antimicrob. Agents Chemother. | pmid:19064898 |
Bimazubute MA et al. | Pre-study and in-study validation of an ultra-high pressure LC method coupled to tandem mass spectrometry for off-line determination of oxytetracycline in nasal secretions of healthy pigs. | 2009 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:19230797 |
Wen X et al. | Degradation of tetracycline and oxytetracycline by crude lignin peroxidase prepared from Phanerochaete chrysosporium--a white rot fungus. | 2009 | Chemosphere | pmid:19232429 |
Uslu MO and BalcioÄŸlu IA | Comparison of the ozonation and Fenton process performances for the treatment of antibiotic containing manure. | 2009 | Sci. Total Environ. | pmid:19232678 |
Fletouris DJ and Papapanagiotou EP | Tissue residue depletion of oxytetracycline after repeated intramuscular administration of Oxysentin 100 in sheep. | 2009 | J. Vet. Pharmacol. Ther. | pmid:19161456 |
Di Giulio G et al. | Live immunization against East Coast fever--current status. | 2009 | Trends Parasitol. | pmid:19135416 |
Yang JF et al. | Dissipation of oxytetracycline in soils under different redox conditions. | 2009 | Environ. Pollut. | pmid:19467565 |
Wang Y et al. | Effects of oxytetracycline and sulfachloropyridazine residues on the reductive activity of Shewanella decolorationis S12. | 2009 | J. Agric. Food Chem. | pmid:19527026 |
Fagutao FF et al. | Differential gene expression in black tiger shrimp, Penaeus monodon, following administration of oxytetracycline and oxolinic acid. | 2009 | Dev. Comp. Immunol. | pmid:19497335 |
Wang P et al. | Identification of OxyE as an ancillary oxygenase during tetracycline biosynthesis. | 2009 | Chembiochem | pmid:19472250 |
Yu D et al. | Effects of administration mode of antibiotics on antibiotic resistance of Enterococcus faecalis in aquatic ecosystems. | 2009 | Chemosphere | pmid:19476969 |
Liang T et al. | Use of oxytetracycline for the treatment of tremor disease in the Chinese mitten crab Eriocheir sinensis. | 2009 | Dis. Aquat. Org. | pmid:19565702 |
Uyaguari M et al. | Acute effects of the antibiotic oxytetracycline on the bacterial community of the grass shrimp, Palaemonetes pugio. | 2009 | Environ. Toxicol. Chem. | pmid:19400597 |
Bao YY et al. | [Influences of cation species on adsorption and desorption of oxytetracycline in two typical soils of China]. | 2009 | Huan Jing Ke Xue | pmid:19402514 |
Jetty A et al. | Continuous production of oxytetracycline in fluidized bed bioreactor by immobilized cells of Streptomyces varsoviensis MTCC-1537: effect of dilution and glucose loading rates. | 2009 | Appl. Biochem. Biotechnol. | pmid:19421724 |