oxytetracycline is a lipid of Polyketides (PK) class. Oxytetracycline is associated with abnormalities such as Infection, X-linked centronuclear myopathy, Bacterial Infections, Heart failure and Onchocerciasis. The involved functions are known as Anabolism, physiological aspects, Transcription, Genetic, Fermentation and Transcriptional Activation. Oxytetracycline often locates in Chromosomes, Flank (surface region), Entire bony skeleton, Bone Marrow and Body tissue. The associated genes with oxytetracycline are Polypeptides, Homologous Gene, Gene Clusters, Locus and CYCS gene. The related lipids are LH 1 and Lipid Peroxides. The related experimental models are Disease model.
To understand associated biological information of oxytetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
oxytetracycline is suspected in Infection, Helminthiasis, Nodule, Bacterial Infections, Yeast infection, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with oxytetracycline
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Disease model are used in the study 'A molecular ecological approach to the detection and designation of the etiological agents of a model polymicrobial disease.' (Antiabong JF et al., 2013).
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Authors | Title | Published | Journal | PubMed Link |
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MINDLIN SZ and ALIKHANIAN SI | [Studies on ultraviolet rays-induced variability and on selection of Act. rimosus (oxytetracycline-producing organism)]. | 1958 Mar-Apr | Antibiotiki (Mosc) | pmid:24544834 |
SHEVIAKOVA OI et al. | [Oxytetracycline and bacteriophage therapy of dysentery in children]. | 1958 Nov-Dec | Antibiotiki (Mosc) | pmid:24545177 |
ORLOVA NV and VERKHOVTSEVA TP | [Comparative physiological characteristics of two strains of Actinomyces rimosus LS-T 118 and 293 producing oxytetracycline]. | 1959 Jan-Feb | Antibiotiki (Mosc) | pmid:24545220 |
ORLOVA NV | [Significance of certain organic acids for biosynthesis of oxytetracycline]. | 1959 Mar-Apr | Antibiotiki (Mosc) | pmid:24545289 |
Rosenblatt JE et al. | Comparison of in vitro activity and clinical pharmacology of doxycycline with other tetracyclines. | 1966 | Antimicrob Agents Chemother (Bethesda) | pmid:4964450 |
SELIGMAN SJ and HEWITT WL | INTERACTION OF PENICILLIN AND TETRACYCLINE AS A FUNCTION OF TIME. | 1963 | Antimicrob Agents Chemother (Bethesda) | pmid:14274932 |
CHU E et al. | RELATIONSHIP OF GROWTH OF THE FIBULA IN PREMATURE INFANTS TO THE ADMINISTRATION OF OXYTETRACYCLINE. | 1963 | Antimicrob Agents Chemother (Bethesda) | pmid:14274998 |
English AR | Activity of 6-methylene oxytetracycline in localized infections in mice. | 1965 | Antimicrob Agents Chemother (Bethesda) | pmid:5883459 |
Colmore JP et al. | Effectiveness of doxycycline treatment in chronic urinary tract infections. | 1966 | Antimicrob Agents Chemother (Bethesda) | pmid:5985237 |
Simon HJ et al. | Clinical pharmacology of antimicrobials in premature infants. 3. Alpha-6-deoxyoxytetracycline (doxycycline). | 1966 | Antimicrob Agents Chemother (Bethesda) | pmid:5985238 |
Huang NN et al. | Doxycycline treatment of children with cystic fibrosis of pancreas. | 1966 | Antimicrob Agents Chemother (Bethesda) | pmid:5985239 |
Gooch WM and Mogabgab WJ | Therapeutic effect of doxycycline upon Mycoplasma pneumoniae pneumonia. | 1970 | Antimicrob Agents Chemother (Bethesda) | pmid:5521347 |
Bah GS et al. | Efficacy of three-week oxytetracycline or rifampin monotherapy compared with a combination regimen against the filarial nematode Onchocerca ochengi. | 2014 | Antimicrob. Agents Chemother. | pmid:24247133 |
Ayling RD et al. | Assessing the in vitro effectiveness of antimicrobials against Mycoplasma mycoides subsp. mycoides small-colony type to reduce contagious bovine pleuropneumonia infection. | 2005 | Antimicrob. Agents Chemother. | pmid:16304194 |
McDonald V et al. | In vitro cultivation of Cryptosporidium parvum and screening for anticryptosporidial drugs. | 1990 | Antimicrob. Agents Chemother. | pmid:2221857 |
Evangelisti DG et al. | Influence of subtherapeutic levels of oxytetracycline on Salmonella typhimurium in swine, alves, and chickens. | 1975 | Antimicrob. Agents Chemother. | pmid:1108781 |
Angrave FE and Avery SV | Antioxidant functions required for insusceptibility of Saccharomyces cerevisiae to tetracycline antibiotics. | 2001 | Antimicrob. Agents Chemother. | pmid:11557497 |
Barza M et al. | Relation between lipophilicity and pharmacological behavior of minocycline, doxycycline, tetracycline, and oxytetracycline in dogs. | 1975 | Antimicrob. Agents Chemother. | pmid:1211925 |
Le Carrou J et al. | Persistence of Mycoplasma hyopneumoniae in experimentally infected pigs after marbofloxacin treatment and detection of mutations in the parC gene. | 2006 | Antimicrob. Agents Chemother. | pmid:16723552 |
Nonaka L and Suzuki S | New Mg2+-dependent oxytetracycline resistance determinant tet 34 in Vibrio isolates from marine fish intestinal contents. | 2002 | Antimicrob. Agents Chemother. | pmid:11959596 |
Avery AM et al. | Iron blocks the accumulation and activity of tetracyclines in bacteria. | 2004 | Antimicrob. Agents Chemother. | pmid:15105154 |
Martinsen B et al. | Temperature-dependent in vitro antimicrobial activity of four 4-quinolones and oxytetracycline against bacteria pathogenic to fish. | 1992 | Antimicrob. Agents Chemother. | pmid:1416857 |
Girard AE et al. | Influence of subtherapeutic levels of a combination of neomycin and oxytetracycline on Salmonella typhimurium in swine, calves, and chickens. | 1976 | Antimicrob. Agents Chemother. | pmid:791090 |
Dheilly A et al. | Resistance gene transfer during treatments for experimental avian colibacillosis. | 2012 | Antimicrob. Agents Chemother. | pmid:21986830 |
Rikihisa Y and Jiang BM | In vitro susceptibilities of Ehrlichia risticii to eight antibiotics. | 1988 | Antimicrob. Agents Chemother. | pmid:3142345 |
Hoeprich PD and Warshauer DM | Entry of four tetracyclines into saliva and tears. | 1974 | Antimicrob. Agents Chemother. | pmid:4840441 |
Byrne-Bailey KG et al. | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. | 2009 | Antimicrob. Agents Chemother. | pmid:19064898 |
Caubet R et al. | A radio frequency electric current enhances antibiotic efficacy against bacterial biofilms. | 2004 | Antimicrob. Agents Chemother. | pmid:15561841 |
Glette J et al. | Influence of tetracyclines on human polymorphonuclear leukocyte function. | 1984 | Antimicrob. Agents Chemother. | pmid:6721468 |
Alarcón B et al. | Screening for new compounds with antiherpes activity. | 1984 | Antiviral Res. | pmid:6517562 |
Senerwa D et al. | Antimicrobial resistance of enteropathogenic Escherichia coli strains from a nosocomial outbreak in Kenya. | 1991 | APMIS | pmid:1859645 |
WALKER HW and AYRES JC | Characteristics of yeasts isolated from processed poultry and the influence of tetracyclines on their growth. | 1959 | Appl Microbiol | pmid:13661871 |
WELLS FE and STADELMAN WJ | Development of yeasts on antibiotic-treated poultry. | 1958 | Appl Microbiol | pmid:13595654 |
Das NK and Chamberlain RE | Chemotherapy of mice experimentally infected with Shigella flexneri. | 1970 | Appl Microbiol | pmid:5422307 |
Isenberg HD | In vitro activity of doxycycline against bacteria from clinical material. | 1967 | Appl Microbiol | pmid:4383870 |
SHAHANI KM and HARPER WJ | Differences in the acid production and phosphorus metabolism of oxytetracylcine sensitive and resistant organisms. | 1958 | Appl Microbiol | pmid:13509648 |
Siebeling RJ et al. | Treatment of Salmonella-Arizona-infected turtle eggs with terramycin and chloromycetin by the temperature-differential egg dip method. | 1975 | Appl Microbiol | pmid:1200629 |
Meyer FP and Bullock GL | Edwardsiella tarda, a new pathogen of channel catfish (Ictalurus punctatus). | 1973 | Appl Microbiol | pmid:4687066 |
Hanus FJ et al. | Antibiotic activity in the presence of agar. | 1967 | Appl Microbiol | pmid:4291669 |
MIKOLAJCIK EM et al. | SOME FACTORS INFLUENCING ACID PRODUCTION BY AN OXYTETRACYCLINE-RESISTANT STRAIN OF STREPTOCOCCUS LACTIS. | 1963 | Appl Microbiol | pmid:14063784 |
MEREDITH WE et al. | CHLORTETRACYCLINE AND OXYTETRACYCLINE RESIDUES IN POULTRY TISSUES AND EGGS. | 1965 | Appl Microbiol | pmid:14264853 |
Bornside GH | Enhancement of antibiotic activity against Staphylococcus aureus by exposure to hyperbaric oxygen. | 1967 | Appl Microbiol | pmid:6077408 |
ALIKHANIAN SI et al. | Hereditary changes of some physiological properties in Streptomyces rimosus. | 1959 | Appl Microbiol | pmid:13650516 |
Siebeling RJ et al. | Evaluation of methods for the isolation of Salmonella and Arizona organisms from pet turtles treated with antimicrobial agents. | 1975 | Appl Microbiol | pmid:1090250 |
ZYGMUNT WA | INFLUENCE OF INORGANIC PHOSPHORUS ON OXYTETRACYCLINE FORMATION BY STREPTOMYCES RIMOSUS. | 1964 | Appl Microbiol | pmid:14170954 |
MEYER FP and COLLAR JD | DESCRIPTION AND TREATMENT OF A PSEUDOMONAS INFECTION IN WHITE CATFISH. | 1964 | Appl Microbiol | pmid:14170955 |
Williams BJ | Factors which influence synergism by neomycin and oxytetracycline. | 1971 | Appl Microbiol | pmid:4930276 |
COREY RR and BYRNES JM | OXYTETRACYCLINE-RESISTANT COLIFORMS IN COMMERCIAL POULTRY PRODUCTS. | 1963 | Appl Microbiol | pmid:14075046 |
MINDLIN SZ et al. | A new hybrid strain of an oxytetracycline-producing organism, Streptomyces rimosus. | 1961 | Appl Microbiol | pmid:13771049 |
BENARDE MA and LITTLEFORD RA | Antibiotic treatment of crab and oyster meats. | 1957 | Appl Microbiol | pmid:13488439 |
Silva FR et al. | Early diagnosis of prostate cancer by citrate determination in urine with europium-oxytetracycline complex. | 2012 | Appl Spectrosc | pmid:22800985 |
Campos JL et al. | Effect of two broad-spectrum antibiotics on activity and stability of continuous nitrifying system. | 2001 | Appl. Biochem. Biotechnol. | pmid:11665802 |
Wang W et al. | The interaction of polysaccharide from Auricularia polytricha with quantum dots and the protection of plasmid DNA from damage. | 2013 | Appl. Biochem. Biotechnol. | pmid:23440638 |
Jetty A et al. | Continuous production of oxytetracycline in fluidized bed bioreactor by immobilized cells of Streptomyces varsoviensis MTCC-1537: effect of dilution and glucose loading rates. | 2009 | Appl. Biochem. Biotechnol. | pmid:19421724 |
Stevens DC et al. | Heterologous expression of the oxytetracycline biosynthetic pathway in Myxococcus xanthus. | 2010 | Appl. Environ. Microbiol. | pmid:20208031 |
Li D et al. | Antibiotic resistance characteristics of environmental bacteria from an oxytetracycline production wastewater treatment plant and the receiving river. | 2010 | Appl. Environ. Microbiol. | pmid:20400569 |
Alcaide E et al. | Occurrence of drug-resistant bacteria in two European eel farms. | 2005 | Appl. Environ. Microbiol. | pmid:15933039 |
Rhodes G et al. | Distribution of oxytetracycline resistance plasmids between aeromonads in hospital and aquaculture environments: implication of Tn1721 in dissemination of the tetracycline resistance determinant tet A. | 2000 | Appl. Environ. Microbiol. | pmid:10966404 |
RodrÃguez C et al. | Lettuce for human consumption collected in Costa Rica contains complex communities of culturable oxytetracycline- and gentamicin-resistant bacteria. | 2006 | Appl. Environ. Microbiol. | pmid:16957206 |
Hansen LH et al. | Detection of oxytetracycline production by Streptomyces rimosus in soil microcosms by combining whole-cell biosensors and flow cytometry. | 2001 | Appl. Environ. Microbiol. | pmid:11133451 |
Schmidt AS et al. | Incidence, distribution, and spread of tetracycline resistance determinants and integron-associated antibiotic resistance genes among motile aeromonads from a fish farming environment. | 2001 | Appl. Environ. Microbiol. | pmid:11722922 |
Adams CA et al. | Molecular characterization of plasmid-mediated oxytetracycline resistance in Aeromonas salmonicida. | 1998 | Appl. Environ. Microbiol. | pmid:9797265 |
Zhang W et al. | Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase. | 2006 | Appl. Environ. Microbiol. | pmid:16597959 |
DePaola A et al. | Phenotypic and genotypic characterization of tetracycline- and oxytetracycline-resistant Aeromonas hydrophila from cultured channel catfish (Ictalurus punctatus) and their environments. | 1988 | Appl. Environ. Microbiol. | pmid:3046493 |
DePaola A et al. | Effect of oxytetracycline-medicated feed on antibiotic resistance of gram-negative bacteria in catfish ponds. | 1995 | Appl. Environ. Microbiol. | pmid:7793953 |
Khachatryan AR et al. | Role of calf-adapted Escherichia coli in maintenance of antimicrobial drug resistance in dairy calves. | 2004 | Appl. Environ. Microbiol. | pmid:14766551 |
Græsbøll K et al. | Effect of Tetracycline Dose and Treatment Mode on Selection of Resistant Coliform Bacteria in Nursery Pigs. | 2017 | Appl. Environ. Microbiol. | pmid:28389548 |
Turker G et al. | Changes in microbial community structures due to varying operational conditions in the anaerobic digestion of oxytetracycline-medicated cow manure. | 2016 | Appl. Microbiol. Biotechnol. | pmid:27026176 |
Liu M et al. | Response of activated sludge to the treatment of oxytetracycline production waste stream. | 2013 | Appl. Microbiol. Biotechnol. | pmid:23188460 |
Vukelić B et al. | Endo-deoxyribonuclease from Streptomyces rimosus. | 1995 | Appl. Microbiol. Biotechnol. | pmid:8590657 |
Shi Y et al. | Characteristics of ARG-carrying plasmidome in the cultivable microbial community from wastewater treatment system under high oxytetracycline concentration. | 2018 | Appl. Microbiol. Biotechnol. | pmid:29332216 |
Yin S et al. | Heterologous expression of oxytetracycline biosynthetic gene cluster in Streptomyces venezuelae WVR2006 to improve production level and to alter fermentation process. | 2016 | Appl. Microbiol. Biotechnol. | pmid:27709288 |
Rigos G et al. | Potential drug (oxytetracycline and oxolinic acid) pollution from Mediterranean sparid fish farms. | 2004 | Aquat. Toxicol. | pmid:15276333 |
Park JC et al. | Adverse effects of two pharmaceuticals acetaminophen and oxytetracycline on life cycle parameters, oxidative stress, and defensome system in the marine rotifer Brachionus rotundiformis. | 2018 | Aquat. Toxicol. | pmid:30189352 |
Feng-Jiao L et al. | Risk assessment of nitrate and oxytetracycline addition on coastal ecosystem functions. | 2014 | Aquat. Toxicol. | pmid:24287139 |
MORIAME G | [A case of Duhring-Brocq disease; treatment by aureomycin and cortisone]. | 1955 | Arch Belg Dermatol Syphiligr | pmid:13303433 |
DEN OTTER G | Results obtained with oxytetracycline in the treatment of chromic infections of the urinary tract and the bile passages. | 1957 | Arch Chir Neerl | pmid:13459747 |
AYRES S and MIHAN R | MOLLUSCUM CONTAGIOSUM OF THE GLANS PENIS. | 1964 | Arch Dermatol | pmid:14096376 |
Frost P et al. | Phototoxic potential of minocycline and doxycycline. | 1972 | Arch Dermatol | pmid:5026677 |
Veien NK and Buus SK | Treatment of epidermolysis bullosa simplex (EBS) with tetracycline. | 2000 | Arch Dermatol | pmid:10724216 |
FRITSCH CJ and FRITSCH WC | EFFECT OF TOPICAL FLUOROMETHOLONE ON INFECTED AND UNINFECTED DERMATOSES. A CLINICAL AND MICROBIOLOGICAL STUDY. | 1964 | Arch Dermatol | pmid:14206867 |
Gloor M et al. | [Influence of tetracycline therapy in acne vulgaris on the quantity and composition of skin surface lipids at varying dosage. I]. | 1972 | Arch Dermatol Forsch | pmid:4260599 |
Gloor M et al. | [Effect of tetracycline therapy in acne vulgaris on amount and composition of skin surface lipids in various dosages. Gas chromatographic studies of its action mechanism]. | 1972 | Arch Dermatol Forsch | pmid:4263449 |
Hummel R et al. | [Characteristics of Staphylococcus aureus strains from pathological processes in swine]. | 1978 | Arch Exp Veterinarmed | pmid:666520 |
Pandey PK | [Prevention and therapy of inflammation of the swimbladder in the carp (Cyprinus carpio L.)]. | 1974 | Arch Exp Veterinarmed | pmid:4460935 |
Kunter E | [Sensitivity of mastitis pathogens to antibiotics and chemotherapeutic agents]. | 1975 | Arch Exp Veterinarmed | pmid:1106346 |
Trolldenier H et al. | [Course of the oxytetracycline blood level after Ursocyclin pro inj. injection in swine]. | 1982 | Arch Exp Veterinarmed | pmid:7168600 |
Bache K et al. | [Determination of pharmacokinetic variables in veterinary medicine using a computer program]. | 1985 | Arch Exp Veterinarmed | pmid:3840351 |
Hummel R and Witte W | [Resistance development in human Staphylococcus aureus due to the use of oxytetracycline and tylosin in industrialized swine production units]. | 1981 | Arch Exp Veterinarmed | pmid:7283644 |
Kunter E and Wittig W | [R and S-streptococcal infections in swine]. | 1976 | Arch Exp Veterinarmed | pmid:985011 |
Schweizer H et al. | [On contamination of tissue cultures with mycoplasmas. 3. Elimination of mycoplasmas from contaminated tissue cultures]. | 1970 | Arch Gesamte Virusforsch | pmid:5466136 |
DE VELASCO GUZMAN R et al. | [Hepatic abscess cured with terramycin]. | 1952 Jan-Feb | Arch Hosp Univ | pmid:12987175 |
IGLESIAS BETANCOURT P et al. | [Endocarditis lenta complicating congenital heart disease; treatment with terramycin]. | 1950 Jul-Aug | Arch Hosp Univ | pmid:14777705 |
Sprössig M and Witzleb W | [Studies on the resistance situation of shigellae]. | 1965 | Arch Hyg Bakteriol | pmid:5333434 |
OEHRING H and FUNK G | [Correlations between toxicity and antibiotic sensitivity of diphteric bacteria]. | 1962 | Arch Hyg Bakteriol | pmid:13939492 |
Linde K et al. | [Cultural determination of enteritis coli in the river water (main drainage channel) with reference to the false larger yield due to fluorescent antibodies]. | 1970 | Arch Hyg Bakteriol | pmid:4920201 |
KUBIKOWSKI P and SZRENIAWSKI Z | THE MECHANISM OF THE NEUROMUSCULAR BLOCKADE BY ANTIBIOTICS. | 1963 | Arch Int Pharmacodyn Ther | pmid:14099599 |
El-Gendi AY et al. | Pharmacokinetic interpretation of some antibiotics in camels. | 1983 | Arch Int Pharmacodyn Ther | pmid:6838280 |
Palladini G and Conforti A | [Microradiographic, histologic and histochemical observations on the parietal bone of the rat fluorochromized with oxytetracycline]. | 1965 | Arch Ital Anat Embriol | pmid:5886972 |
SCHIRALDI O et al. | [HISTO-ENZYMATIC ASPECT OF THE SMALL INTESTINE OF RATS TREATED WITH ANTIBIOTICS (TERRAMYCIN AND NEOMYCIN)]. | 1963 | Arch Ital Anat Istol Patol | pmid:14122127 |