oxytetracycline is a lipid of Polyketides (PK) class. Oxytetracycline is associated with abnormalities such as Infection, X-linked centronuclear myopathy, Bacterial Infections, Heart failure and Onchocerciasis. The involved functions are known as Anabolism, physiological aspects, Transcription, Genetic, Fermentation and Transcriptional Activation. Oxytetracycline often locates in Chromosomes, Flank (surface region), Entire bony skeleton, Bone Marrow and Body tissue. The associated genes with oxytetracycline are Polypeptides, Homologous Gene, Gene Clusters, Locus and CYCS gene. The related lipids are LH 1 and Lipid Peroxides. The related experimental models are Disease model.
To understand associated biological information of oxytetracycline, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
oxytetracycline is suspected in Infection, Helminthiasis, Nodule, Bacterial Infections, Yeast infection, pathologic fistula and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with oxytetracycline
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Disease model are used in the study 'A molecular ecological approach to the detection and designation of the etiological agents of a model polymicrobial disease.' (Antiabong JF et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Ma T et al. | Toxicity of OTC to Ipomoea aquatica Forsk. and to microorganisms in a long-term sewage-irrigated farmland soil. | 2016 | Environ Sci Pollut Res Int | pmid:27083912 |
Liu Y et al. | Quantitative assessment on the contribution of direct photolysis and radical oxidation in photochemical degradation of 4-chlorophenol and oxytetracycline. | 2016 | Environ Sci Pollut Res Int | pmid:27055892 |
Wang Y et al. | Comparison of oxytetracycline degradation behavior in pig manure with different antibiotic addition methods. | 2015 | Environ Sci Pollut Res Int | pmid:26278905 |
Alavi N et al. | Assessment of oxytetracycline and tetracycline antibiotics in manure samples in different cities of Khuzestan Province, Iran. | 2015 | Environ Sci Pollut Res Int | pmid:26165993 |
Kim SY et al. | Occurrence and diversity of tetracycline resistance genes in the agricultural soils of South Korea. | 2016 | Environ Sci Pollut Res Int | pmid:27638788 |
Li Y et al. | Dissipation kinetics of oxytetracycline, tetracycline, and chlortetracycline residues in soil. | 2016 | Environ Sci Pollut Res Int | pmid:27072037 |
Han C et al. | UV-visible light-activated Ag-decorated, monodisperse TiO2 aggregates for treatment of the pharmaceutical oxytetracycline. | 2014 | Environ Sci Pollut Res Int | pmid:24217967 |
Wieczerzak M et al. | Impact of selected drugs and their binary mixtures on the germination of Sorghum bicolor (sorgo) seeds. | 2018 | Environ Sci Pollut Res Int | pmid:29705907 |
Nakano T et al. | Effect of excessive doses of oxytetracycline on stress-related biomarker expression in coho salmon. | 2018 | Environ Sci Pollut Res Int | pmid:26111749 |
Wang J et al. | Effects of thermophilic composting on oxytetracycline, sulfamethazine, and their corresponding resistance genes in swine manure. | 2015 | Environ Sci Process Impacts | pmid:26216606 |
Wang X et al. | Effects of oxytetracycline on archaeal community, and tetracycline resistance genes in anaerobic co-digestion of pig manure and wheat straw. | 2016 | Environ Technol | pmid:27115735 |
Zheng D et al. | Performance comparison of biofilm and suspended sludge from a sequencing batch biofilm reactor treating mariculture wastewater under oxytetracycline stress. | 2016 | Environ Technol | pmid:26854088 |
Çelebi H et al. | Removals of non-analogous OTC and BaP in AMCBR with and without primary substrate. | 2016 | Environ Technol | pmid:26670775 |
Ma W et al. | Treatment of antibiotics wastewater utilizing successive hydrolysis, denitrification and nitrification. | 2002 | Environ Technol | pmid:12118620 |
Akyol C et al. | Acidification of non-medicated and oxytetracycline-medicated cattle manures during anaerobic digestion. | 2014 Sep-Oct | Environ Technol | pmid:25145191 |
Giordano R et al. | Effect of a high dose of three antibiotics on the reproduction of a parthenogenetic strain of Folsomia candida (Isotomidae: Collembola). | 2010 | Environ. Entomol. | pmid:22127168 |
Kleinstreuer NC et al. | Environmental impact on vascular development predicted by high-throughput screening. | 2011 | Environ. Health Perspect. | pmid:21788198 |
Liu J et al. | Soil-borne reservoirs of antibiotic-resistant bacteria are established following therapeutic treatment of dairy calves. | 2016 | Environ. Microbiol. | pmid:26486254 |
Jin X et al. | The effect of Cu(2+) chelation on the direct photolysis of oxytetracycline: A study assisted by spectroscopy analysis and DFT calculation. | 2016 | Environ. Pollut. | pmid:27155101 |
Leal JF et al. | Use of sunlight to degrade oxytetracycline in marine aquaculture's waters. | 2016 | Environ. Pollut. | pmid:27049790 |
Kay P et al. | A lysimeter experiment to investigate the leaching of veterinary antibiotics through a clay soil and comparison with field data. | 2005 | Environ. Pollut. | pmid:15589660 |
Kong WD et al. | Uptake of oxytetracycline and its phytotoxicity to alfalfa (Medicago sativa L.). | 2007 | Environ. Pollut. | pmid:17029682 |
Gomiero A and Viarengo A | Effects of elevated temperature on the toxicity of copper and oxytetracycline in the marine model, Euplotes crassus: a climate change perspective. | 2014 | Environ. Pollut. | pmid:25163430 |
Kong WD et al. | The veterinary antibiotic oxytetracycline and Cu influence functional diversity of the soil microbial community. | 2006 | Environ. Pollut. | pmid:16413090 |
Chen C et al. | Occurrence of antibiotics and antibiotic resistances in soils from wastewater irrigation areas in Beijing and Tianjin, China. | 2014 | Environ. Pollut. | pmid:25016103 |
Brain RA et al. | Effects of a mixture of tetracyclines to Lemna gibba and Myriophyllum sibiricum evaluated in aquatic microcosms. | 2005 | Environ. Pollut. | pmid:15996801 |
Zhang Y et al. | Insights into aquatic toxicities of the antibiotics oxytetracycline and ciprofloxacin in the presence of metal: complexation versus mixture. | 2012 | Environ. Pollut. | pmid:22475550 |
Wallace JS et al. | Occurrence and transformation of veterinary antibiotics and antibiotic resistance genes in dairy manure treated by advanced anaerobic digestion and conventional treatment methods. | 2018 | Environ. Pollut. | pmid:29455089 |
Chen F et al. | Distribution and accumulation of endocrine-disrupting chemicals and pharmaceuticals in wastewater irrigated soils in Hebei, China. | 2011 | Environ. Pollut. | pmid:21477905 |
Hanson ML et al. | Field assessment of oxytetracycline exposure to the freshwater macrophytes Egeria densa Planch. and Ceratophyllum demersum L. | 2006 | Environ. Pollut. | pmid:16253408 |
Duan M et al. | Effects of biochar on reducing the abundance of oxytetracycline, antibiotic resistance genes, and human pathogenic bacteria in soil and lettuce. | 2017 | Environ. Pollut. | pmid:28284554 |
Tian Z et al. | Chronic impacts of oxytetracycline on mesophilic anaerobic digestion of excess sludge: Inhibition of hydrolytic acidification and enrichment of antibiotic resistome. | 2018 | Environ. Pollut. | pmid:29449116 |
Zhou L et al. | Environmental concentrations of antibiotics impair zebrafish gut health. | 2018 | Environ. Pollut. | pmid:29291524 |
Leal JF et al. | Antibacterial activity of oxytetracycline photoproducts in marine aquaculture's water. | 2017 | Environ. Pollut. | pmid:27769773 |
Yang JF et al. | Dissipation of oxytetracycline in soils under different redox conditions. | 2009 | Environ. Pollut. | pmid:19467565 |
Zhang W et al. | Accumulation of tetracycline resistance genes in aquatic biofilms due to periodic waste loadings from swine lagoons. | 2009 | Environ. Sci. Technol. | pmid:19921873 |
Oleszczuk P et al. | Adsorption and desorption of oxytetracycline and carbamazepine by multiwalled carbon nanotubes. | 2009 | Environ. Sci. Technol. | pmid:20000507 |
Bui TX and Choi H | Comment on "Adsorption and desorption of oxytetracycline and carbamazepine by multiwalled carbon nanotubes". | 2010 | Environ. Sci. Technol. | pmid:20469851 |
Simon NS | Loosely bound oxytetracycline in riverine sediments from two tributaries of the Chesapeake bay. | 2005 | Environ. Sci. Technol. | pmid:15952351 |
Rosenblum ES et al. | Effects of temperature on host-pathogen-drug interactions in red abalone, Haliotis rufescens, determined by 1H NMR metabolomics. | 2006 | Environ. Sci. Technol. | pmid:17154019 |
Figueroa RA and MacKay AA | Sorption of oxytetracycline to iron oxides and iron oxide-rich soils. | 2005 | Environ. Sci. Technol. | pmid:16190225 |
Kulshrestha P et al. | Investigating the molecular interactions of oxytetracycline in clay and organic matter: insights on factors affecting its mobility in soil. | 2004 | Environ. Sci. Technol. | pmid:15352447 |
Rubert KF and Pedersen JA | Kinetics of oxytetracycline reaction with a hydrous manganese oxide. | 2006 | Environ. Sci. Technol. | pmid:17180969 |
Engemann CA et al. | Fate of tetracycline resistance genes in aquatic systems: migration from the water column to peripheral biofilms. | 2008 | Environ. Sci. Technol. | pmid:18754359 |
Knapp CW et al. | Indirect evidence of transposon-mediated selection of antibiotic resistance genes in aquatic systems at low-level oxytetracycline exposures. | 2008 | Environ. Sci. Technol. | pmid:18754392 |
Liu M et al. | Abundance and distribution of tetracycline resistance genes and mobile elements in an oxytetracycline production wastewater treatment system. | 2012 | Environ. Sci. Technol. | pmid:22709269 |
Aristilde L et al. | Interactions of oxytetracycline with a smectite clay: a spectroscopic study with molecular simulations. | 2010 | Environ. Sci. Technol. | pmid:20866047 |
Carrasquillo AJ et al. | Sorption of ciprofloxacin and oxytetracycline zwitterions to soils and soil minerals: influence of compound structure. | 2008 | Environ. Sci. Technol. | pmid:18983086 |
DeLorenzo ME et al. | Exposure of the grass shrimp, Palaemonetes pugio, to antimicrobial compounds affects associated Vibrio bacterial density and development of antibiotic resistance. | 2016 | Environ. Toxicol. | pmid:25348372 |
Rose PE and Pedersen JA | Fate of oxytetracycline in streams receiving aquaculture discharges: model simulations. | 2005 | Environ. Toxicol. Chem. | pmid:15683166 |
Peng FJ et al. | Antibacterial activity of the soil-bound antimicrobials oxytetracycline and ofloxacin. | 2014 | Environ. Toxicol. Chem. | pmid:24408539 |
ter Laak TL et al. | The effect of pH and ionic strength on the sorption of sulfachloropyridazine, tylosin, and oxytetracycline to soil. | 2006 | Environ. Toxicol. Chem. | pmid:16629129 |
ter Laak TL et al. | Estimation of soil sorption coefficients of veterinary pharmaceuticals from soil properties. | 2006 | Environ. Toxicol. Chem. | pmid:16629132 |
Zounková R et al. | Complex evaluation of ecotoxicity and genotoxicity of antimicrobials oxytetracycline and flumequine used in aquaculture. | 2011 | Environ. Toxicol. Chem. | pmid:21312248 |
Kay P et al. | Fate of veterinary antibiotics in a macroporous tile drained clay soil. | 2004 | Environ. Toxicol. Chem. | pmid:15180364 |
Li D et al. | Determination and fate of oxytetracycline and related compounds in oxytetracycline production wastewater and the receiving river. | 2008 | Environ. Toxicol. Chem. | pmid:18092864 |
Jones AD et al. | Factors influencing the sorption of oxytetracycline to soils. | 2005 | Environ. Toxicol. Chem. | pmid:15839547 |
Thiele-Bruhn S | Microbial inhibition by pharmaceutical antibiotics in different soils--dose-response relations determined with the iron(III) reduction test. | 2005 | Environ. Toxicol. Chem. | pmid:15839561 |
Goetsch HE et al. | Oxytetracycline interactions at the soil-water interface: effects of environmental surfaces on natural transformation and growth inhibition of Azotobacter vinelandii. | 2012 | Environ. Toxicol. Chem. | pmid:22821843 |
Uyaguari M et al. | Acute effects of the antibiotic oxytetracycline on the bacterial community of the grass shrimp, Palaemonetes pugio. | 2009 | Environ. Toxicol. Chem. | pmid:19400597 |
Gao M et al. | Interactive effect of oxytetracycline and lead on soil enzymatic activity and microbial biomass. | 2013 | Environ. Toxicol. Pharmacol. | pmid:23892283 |
Gao M et al. | Combined effects of oxytetracycline and Pb on earthworm Eisenia fetida. | 2014 | Environ. Toxicol. Pharmacol. | pmid:24607684 |
Wang C et al. | The oxidative stress response of oxytetracycline in the ciliate Pseudocohnilembus persalinus. | 2017 | Environ. Toxicol. Pharmacol. | pmid:28881225 |
Suga N et al. | Risk assessment of oxytetracycline in water phase to major sediment bacterial community: a water-sediment microcosm study. | 2013 | Environ. Toxicol. Pharmacol. | pmid:23619519 |
Slana M and Dolenc MS | Environmental Risk Assessment of antimicrobials applied in veterinary medicine-A field study and laboratory approach. | 2013 | Environ. Toxicol. Pharmacol. | pmid:23274419 |
Rodrigues S et al. | Histological alterations in gills and liver of rainbow trout (Oncorhynchus mykiss) after exposure to the antibiotic oxytetracycline. | 2017 | Environ. Toxicol. Pharmacol. | pmid:28599186 |
Oliveira R et al. | Effects of oxytetracycline and amoxicillin on development and biomarkers activities of zebrafish (Danio rerio). | 2013 | Environ. Toxicol. Pharmacol. | pmid:24008007 |
Gao M et al. | Avoidance behavior of Eisenia fetida in oxytetracycline- and heavy metal-contaminated soils. | 2016 | Environ. Toxicol. Pharmacol. | pmid:27665306 |
Mihciokur H and Oguz M | Removal of oxytetracycline and determining its biosorption properties on aerobic granular sludge. | 2016 | Environ. Toxicol. Pharmacol. | pmid:27485178 |
Tang Z et al. | Improved oxytetracycline production in Streptomyces rimosus M4018 by metabolic engineering of the G6PDH gene in the pentose phosphate pathway. | 2011 | Enzyme Microb. Technol. | pmid:22112266 |
Yu L et al. | Oxytetracycline biosynthesis improvement in Streptomyces rimosus following duplication of minimal PKS genes. | 2012 | Enzyme Microb. Technol. | pmid:22500899 |
Carević O and Cerlek N | The inhibitory effect of oxytetracycline on the glucose degradation in human erythrocytes. | 1971 | Enzymologia | pmid:4940282 |
Sanciu G et al. | Outbreak of mastitis in sheep caused by multi-drug resistant Enterococcus faecalis in Sardinia, Italy. | 2013 | Epidemiol. Infect. | pmid:22595402 |
Sasaki Y et al. | Prevalence and antimicrobial susceptibility of Salmonella in Japanese broiler flocks. | 2012 | Epidemiol. Infect. | pmid:22281015 |
Nijsten R et al. | Resistance in faecal Escherichia coli isolated from pigfarmers and abattoir workers. | 1994 | Epidemiol. Infect. | pmid:8062879 |
O'Connor AM et al. | Verotoxins in commensal Escherichia coli in cattle: the effect of injectable subcutaneous oxytetracycline in addition to in-feed chlortetracycline on prevalence. | 2004 | Epidemiol. Infect. | pmid:14979593 |
Pilsworth RC and Head MJ | A study of ten cases of focal peritarsal infection as a cause of severe lameness in the thoroughbred racehorse: clinical signs, differential diagnosis, treatment and outcome. | 2001 | Equine Vet. J. | pmid:11469769 |
Horspool LJ and McKellar QA | Disposition of oxytetracycline in horses, ponies and donkeys after intravenous administration. | 1990 | Equine Vet. J. | pmid:2209525 |
Sampieri F et al. | Tetracycline therapy of Lawsonia intracellularis enteropathy in foals. | 2006 | Equine Vet. J. | pmid:16411593 |
HAENEL H and GERRIETS E | [Feeding of chickens with tetracycline in nutritive, therapeutic and overdosage quantities]. | 1961 | Ernahrungsforsch Ber Mitt | pmid:13710402 |
Ruth M et al. | A clinical comparison of hydrocortisone butyrate with oxytetracycline/hydrocortisone acetate-polymyxin B in the local treatment of acute external otitis. | 1990 | Eur Arch Otorhinolaryngol | pmid:2156538 |
Yildirim E et al. | Rapid pleurodesis in symptomatic malignant pleural effusion. | 2005 | Eur J Cardiothorac Surg | pmid:15621465 |
Talevi A et al. | Prediction of drug intestinal absorption by new linear and non-linear QSPR. | 2011 | Eur J Med Chem | pmid:21112128 |
Machán V et al. | SORB-GEL method of analysis of 99mTc-labelled compounds. | 1980 | Eur J Nucl Med | pmid:7379804 |
Liu SS et al. | Continuous forces are more effective than intermittent forces in expanding sutures. | 2010 | Eur J Orthod | pmid:20053718 |
Chetoni P et al. | Silicone rubber/hydrogel composite ophthalmic inserts: preparation and preliminary in vitro/in vivo evaluation. | 1998 | Eur J Pharm Biopharm | pmid:9700030 |
de Jonge HR and Hülsmann WC | Inhibition of mitochondrial-protein synthesis in rat small-intestinal epithelium. | 1973 | Eur. J. Biochem. | pmid:4347093 |
Hobson D et al. | Evaluation of a seven day course of oxytetracycline in women with chlamydial cervicitis. | 1986 | Eur. J. Clin. Microbiol. | pmid:3780714 |
Ridgway GL et al. | The activity of ciprofloxacin and other 4-quinolones against Chlamydia trachomatis and Mycoplasmas in vitro. | 1984 | Eur. J. Clin. Microbiol. | pmid:6237903 |
Czeizel AE and Rockenbauer M | A population-based case-control teratologic study of oral oxytetracycline treatment during pregnancy. | 2000 | Eur. J. Obstet. Gynecol. Reprod. Biol. | pmid:10659913 |
Hobusch D and Putzke HP | [Effect of oxytetracycline (OTC) on the secretion kinetics of the rat exocrine pancreas]. | 1971 | Exp Pathol (Jena) | pmid:4335637 |
METZGER JF et al. | Antibiotics in tissue culture. | 1954 | Exp. Cell Res. | pmid:13173487 |
Chandler HL et al. | The role of the slug transcription factor in cell migration during corneal re-epithelialization in the dog. | 2007 | Exp. Eye Res. | pmid:17196588 |
Terzian LA et al. | The sporogonous of Plasmodium vivax in Anopheles mosquitoes as a system for evaluating the prophylactic and curative capabilities of potential antimalarial compounds. | 1968 | Exp. Parasitol. | pmid:4876903 |
Todorovic RA et al. | Babesia bigemina, Babesia argentina, and Anaplasma marginale: Coinfectious immunity in bovines. | 1975 | Exp. Parasitol. | pmid:1123013 |
Speybroeck N et al. | Titrating Theileria parva: single stocks against combination of stocks. | 2008 | Exp. Parasitol. | pmid:18155195 |
Graf E and Benz G | Toxicity of streptomycin and terramycin, and influence on growth and developmental time of Drosophila melanogaster. | 1970 | Experientia | pmid:5492218 |
Lal OP | Synergism of terramycin to inhibit the reproductivity of aphis fabae scop. | 1972 | Experientia | pmid:5045184 |
Katsuragi T and Suzuki T | Ouabain-induced release of extraneuronal catecholamine in the isolated guinea-pig vas deferens. | 1976 | Experientia | pmid:950020 |
Nogge G | Sterility in tsetse flies (Glossina morsitans Westwood) caused by loss of symbionts. | 1976 | Experientia | pmid:986317 |