Chaetoglobosins

Chaetoglobosins is a lipid of Polyketides (PK) class. The involved functions are known as Drug Interactions, cell motility, Polymerization, Cell Cycle Arrest and Cytokinesis. Chaetoglobosins often locates in host, nucleocapsid location, Microfilaments and Skeletal system. The associated genes with Chaetoglobosins are TP53 gene.

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Introduction

To understand associated biological information of Chaetoglobosins, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Chaetoglobosins?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Chaetoglobosins

MeSH term MeSH ID Detail
Leukemia, Lymphocytic, Chronic, B-Cell D015451 25 associated lipids
Cholangiocarcinoma D018281 7 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Chaetoglobosins

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Chaetoglobosins?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Chaetoglobosins?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Chaetoglobosins?

There are no associated biomedical information in the current reference collection.

What genes are associated with Chaetoglobosins?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Chaetoglobosins?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Chaetoglobosins

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Authors Title Published Journal PubMed Link
Dou H et al. Chaetoglobosin Fex from the marine-derived endophytic fungus inhibits induction of inflammatory mediators via Toll-like receptor 4 signaling in macrophages. 2011 Biol. Pharm. Bull. pmid:22130243
Thohinung S et al. Cytotoxic 10-(indol-3-yl)-[13]cytochalasans from the fungus Chaetomium elatum ChE01. 2010 Arch. Pharm. Res. pmid:20803114
Cui CM et al. Cytoglobosins A-G, cytochalasans from a marine-derived endophytic fungus, Chaetomium globosum QEN-14. 2010 J. Nat. Prod. pmid:20225834
Zhang J et al. Cytotoxic chaetoglobosins from the endophyte Chaetomium globosum. 2010 Planta Med. pmid:20486076
Qin JC et al. Bioactive metabolites produced by Chaetomium globosum, an endophytic fungus isolated from Ginkgo biloba. 2009 Bioorg. Med. Chem. Lett. pmid:19246197
Sidorova TS and Matesic DF Protective effect of the natural product, chaetoglobosin K, on lindane- and dieldrin-induced changes in astroglia: identification of activated signaling pathways. 2008 Pharm. Res. pmid:18040759
Fogle MR et al. Heat stability of chaetoglobosins A and C. 2008 Can. J. Microbiol. pmid:18449228
Fogle MR et al. Growth and mycotoxin production by Chaetomium globosum. 2007 Mycopathologia pmid:17551849
Matesic DF et al. Inhibition of cytokinesis and akt phosphorylation by chaetoglobosin K in ras-transformed epithelial cells. 2006 Cancer Chemother. Pharmacol. pmid:16254733
Ding G et al. Chaetoglobosin U, a cytochalasan alkaloid from endophytic Chaetomium globosum IFB-E019. 2006 J. Nat. Prod. pmid:16499339