SCHEMBL105486

Kakonein is a lipid of Polyketides (PK) class. Kakonein is associated with abnormalities such as Fatty Liver, Chronic liver disease, Morphologically altered structure, Hypertensive disease and Cardiovascular Diseases. The involved functions are known as protein expression, Extravasation, Liver damage, mRNA Expression and cell activation. Kakonein often locates in Body tissue, Hepatic, Microvilli, Cytoplasm and Membrane. The associated genes with Kakonein are TJP1 gene, CD14 gene, iberiotoxin, AT-Rich Interactive Domain-Containing Protein 1A and NKS1 gene. The related lipids are dehydrosoyasaponin I and Steroids. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of SCHEMBL105486, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with SCHEMBL105486?

SCHEMBL105486 is suspected in Chronic liver disease, Hypertensive disease, Cardiovascular Diseases, Myocardial Infarction, Cerebrovascular accident, Fatty Liver and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with SCHEMBL105486

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Lead Poisoning D007855 4 associated lipids
Adenocarcinoma D000230 166 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Fatty Liver D005234 48 associated lipids
Per page 10 20 50 | Total 43

PubChem Associated disorders and diseases

What pathways are associated with SCHEMBL105486

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with SCHEMBL105486?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with SCHEMBL105486?


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Function Cross reference Weighted score Related literatures

What lipids are associated with SCHEMBL105486?

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What genes are associated with SCHEMBL105486?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with SCHEMBL105486?

Knock-out

Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with SCHEMBL105486

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Per page 10 20 50 100 | Total 919
Authors Title Published Journal PubMed Link
Zhou Y et al. [Comparative study on pharmacological effects of various species of Pueraria]. 1995 Zhongguo Zhong Yao Za Zhi pmid:8679082
Chen L et al. [Effect of puerarin on cerebral blood flow in dogs]. 1995 Zhongguo Zhong Yao Za Zhi pmid:8679097
Zhang X et al. [Determination of puerarin in radix Puerariae and yufengningxin tablets by HPLC]. 1995 Zhongguo Zhong Yao Za Zhi pmid:8561884
Zhang L et al. [Determination of puerarin in various kinds of radix Puerariae from different places]. 1995 Zhongguo Zhong Yao Za Zhi pmid:7576135
Keung WM and Vallee BL Therapeutic lessons from traditional Oriental medicine to contemporary Occidental pharmacology. 1994 EXS pmid:8032168
Wang LY et al. [Effects of puerarin on cat vascular smooth muscle in vitro]. 1994 Zhongguo Yao Li Xue Bao pmid:8010117
Kang RX [The intraocular pressure depressive effect of puerarin]. 1993 Zhonghua Yan Ke Za Zhi pmid:7912669
Yasuda T et al. [A simultaneous determination of daidzin and puerarin and determination of daidzein in Oriental pharmaceutical decoctions containing puerariae radix by ion-pair high-performance liquid chromatography]. 1993 Yakugaku Zasshi pmid:8301541
Yu S et al. [Comparison of constituents in Pueraria thomsonii Benth before and after processing]. 1992 Zhongguo Zhong Yao Za Zhi pmid:1292491
Fan LL et al. Protective effect of puerarin against myocardial reperfusion injury. Myocardial metabolism and ultrastructure. 1992 Chin. Med. J. pmid:1451545