MeSH term | MeSH ID | Detail |
---|---|---|
Hyperglycemia | D006943 | 21 associated lipids |
Prostatic Neoplasms | D011471 | 126 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
Neoplasms, Germ Cell and Embryonal | D009373 | 4 associated lipids |
Tectorigenin is a lipid of Polyketides (PK) class. Tectorigenin is associated with abnormalities such as Estrogenic effect. The involved functions are known as Phosphorylation, Metabolic Inhibition, Signal, AKT Signaling Pathway and Signal Transduction. Tectorigenin often locates in Skeletal system, Solitary microtubule component of centriole or axonemal complex, Blood and Entire gastrointestinal tract. The associated genes with Tectorigenin are IKBKE gene, BCL2 gene, CFLAR gene, XIAP gene and BCL2L1 gene. The related lipids are 21-hydroxy-9beta,10alpha-pregna-5,7-diene-3-ol-20-one.
To understand associated biological information of Tectorigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tectorigenin is suspected in Estrogenic effect and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tectorigenin
MeSH term | MeSH ID | Detail |
---|---|---|
Hyperglycemia | D006943 | 21 associated lipids |
Prostatic Neoplasms | D011471 | 126 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
Neoplasms, Germ Cell and Embryonal | D009373 | 4 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Zeng L et al. | Suppression of human breast cancer cells by tectorigenin through downregulation of matrix metalloproteinases and MAPK signaling in vitro. | 2018 | Mol Med Rep | pmid:29359782 |
BukviÄki D et al. | Secondary metabolites from endemic species Iris adriatica Trinajstić ex Mitić (Iridaceae). | 2018 | Nat. Prod. Res. | pmid:29126369 |
Lee SY et al. | Tectorigenin Promotes Osteoblast Differentiation and Bone Healing, but Suppresses Osteoclast Differentiation and Bone Resorption. | 2018 | Mol. Cells | pmid:29764006 |
Applová L et al. | The isoflavonoid tectorigenin has better antiplatelet potential than acetylsalicylic acid. | 2017 | Phytomedicine | pmid:28991640 |
Zhang Y et al. | Characterization and evaluation of a self-microemulsifying drug delivery system containing tectorigenin, an isoflavone with low aqueous solubility and poor permeability. | 2017 | Drug Deliv | pmid:28283000 |
Zhan G et al. | Antitumor, Antioxidant, and Nitrite Scavenging Effects of Chinese Water Chestnut (Eleocharis dulcis) Peel Flavonoids. | 2016 | J. Food Sci. | pmid:27603811 |
Guo Y et al. | Tectorigenin inhibits osteosarcoma cell migration through downregulation of matrix metalloproteinases in vitro. | 2016 | Anticancer Drugs | pmid:26991068 |
Shuai S et al. | Preparation, characterization and in vitro/vivo evaluation of tectorigenin solid dispersion with improved dissolution and bioavailability. | 2016 | Eur J Drug Metab Pharmacokinet | pmid:25669445 |
Zhang R et al. | Protective Effect of an Isoflavone, Tectorigenin, Against Oxidative Stress-induced Cell Death via Catalase Activation. | 2016 | J Cancer Prev | pmid:28053960 |
Gampe N et al. | Characterization and identification of isoflavonoid glycosides in the root of Spiny restharrow (Ononis spinosa L.) by HPLC-QTOF-MS, HPLC-MS/MS and NMR. | 2016 | J Pharm Biomed Anal | pmid:26874257 |