MeSH term | MeSH ID | Detail |
---|---|---|
Hyperglycemia | D006943 | 21 associated lipids |
Prostatic Neoplasms | D011471 | 126 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
Neoplasms, Germ Cell and Embryonal | D009373 | 4 associated lipids |
Tectorigenin is a lipid of Polyketides (PK) class. Tectorigenin is associated with abnormalities such as Estrogenic effect. The involved functions are known as Phosphorylation, Metabolic Inhibition, Signal, AKT Signaling Pathway and Signal Transduction. Tectorigenin often locates in Skeletal system, Solitary microtubule component of centriole or axonemal complex, Blood and Entire gastrointestinal tract. The associated genes with Tectorigenin are IKBKE gene, BCL2 gene, CFLAR gene, XIAP gene and BCL2L1 gene. The related lipids are 21-hydroxy-9beta,10alpha-pregna-5,7-diene-3-ol-20-one.
To understand associated biological information of Tectorigenin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tectorigenin is suspected in Estrogenic effect and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tectorigenin
MeSH term | MeSH ID | Detail |
---|---|---|
Hyperglycemia | D006943 | 21 associated lipids |
Prostatic Neoplasms | D011471 | 126 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
Neoplasms, Germ Cell and Embryonal | D009373 | 4 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Yang M et al. | Comparative pharmacokinetic profiles of tectorigenin in rat plasma by UPLC-MS/MS after oral administration of Iris tectorum Maxim extract and pure tectoridin. | 2015 | J Pharm Biomed Anal | pmid:26004225 |
Li QY et al. | Tectorigenin regulates adipogenic differentiation and adipocytokines secretion via PPARγ and IKK/NF-κB signaling. | 2015 | Pharm Biol | pmid:25856699 |
Amin A et al. | Tectorigenin ablates the inflammation-induced epithelial-mesenchymal transition in a co-culture model of human lung carcinoma. | 2015 | Pharmacol Rep | pmid:25712668 |
Shi Z et al. | Excretion of tectorigenin in rat urine orally administrated at different dosages by ultra-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry. | 2015 | Eur J Drug Metab Pharmacokinet | pmid:24789580 |
Ma CH et al. | Tectorigenin inhibits the inflammation of LPS-induced acute lung injury in mice. | 2014 | Chin J Nat Med | pmid:25480515 |
Wang S et al. | Simultaneous determination of tectorigenin and its metabolites in rat plasma by ultra performance liquid chromatography/quadrupole time-of-flight mass spectrometry. | 2013 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:23872519 |
Wang Q et al. | Application of an efficient strategy for discovery and purification of bioactive compounds from Chinese herbal medicines, a case study on the Puerariae thomsonii Flos. | 2013 | J Pharm Biomed Anal | pmid:23312381 |
Hasibeder A et al. | Phytoestrogens regulate the proliferation and expression of stem cell factors in cell lines of malignant testicular germ cell tumors. | 2013 | Int. J. Oncol. | pmid:23969837 |
Wang Q et al. | Tectorigenin Attenuates Palmitate-Induced Endothelial Insulin Resistance via Targeting ROS-Associated Inflammation and IRS-1 Pathway. | 2013 | PLoS ONE | pmid:23840461 |
Wang H et al. | Metabolism and excretion of kakkalide and its metabolites in rat urine, bile, and feces as determined by HPLC/UV and LC/MS/MS. | 2013 | Planta Med. | pmid:24108437 |