MeSH term | MeSH ID | Detail |
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Prostatic Neoplasms | D011471 | 126 associated lipids |
Psoralidin is a lipid of Polyketides (PK) class. Psoralidin is associated with abnormalities such as Infection, Vitiligo, Psoriasis, Morphologically altered structure and Cyst. The involved functions are known as Signal Transduction, Apoptosis, DNA Binding, Ectopic Expression and kinase activity. Psoralidin often locates in Cytoplasmic matrix, Cytoplasmic, Body tissue, Cytoplasm and Cell membrane. The associated genes with Psoralidin are MSMP gene, BCL2 gene, PDZD2 gene, PKD2 gene and SART3 gene. The related experimental models are Xenograft Model.
To understand associated biological information of Psoralidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Psoralidin is suspected in Morphologically altered structure, Cyst, Infection, Vitiligo, Psoriasis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Psoralidin
MeSH term | MeSH ID | Detail |
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Prostatic Neoplasms | D011471 | 126 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Xenograft Model are used in the study 'Activating stress-activated protein kinase-mediated cell death and inhibiting epidermal growth factor receptor signaling: a promising therapeutic strategy for prostate cancer.' (Kumar R et al., 2010).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Alalaiwe A et al. | The active compounds derived from Psoralea corylifolia for photochemotherapy against psoriasis-like lesions: The relationship between structure and percutaneous absorption. | 2018 | Eur J Pharm Sci | pmid:30153523 |
Zhai Y et al. | The higher osteoprotective activity of psoralidin in vivo than coumestrol is attributed by its presence of an isopentenyl group and through activated PI3K/Akt axis. | 2018 | Biomed. Pharmacother. | pmid:29710518 |
Rao Z et al. | Protective effects of psoralidin on IL‑1β‑induced chondrocyte apoptosis. | 2018 | Mol Med Rep | pmid:29257269 |
Kong L et al. | Psoralidin suppresses osteoclastogenesis in BMMs and attenuates LPS-mediated osteolysis by inhibiting inflammatory cytokines. | 2017 | Int. Immunopharmacol. | pmid:28779592 |
Chen CH et al. | Isoflavones and anti-inflammatory constituents from the fruits of Psoralea corylifolia. | 2017 | Phytochemistry | pmid:28825980 |
Pal D et al. | Inhibition of autophagy prevents cadmium-induced prostate carcinogenesis. | 2017 | Br. J. Cancer | pmid:28588318 |
Zhai Y et al. | Psoralidin, a prenylated coumestan, as a novel anti-osteoporosis candidate to enhance bone formation of osteoblasts and decrease bone resorption of osteoclasts. | 2017 | Eur. J. Pharmacol. | pmid:28283388 |
Pal D et al. | Targeting aberrant expression of Notch-1 in ALDH cancer stem cells in breast cancer. | 2017 | Mol. Carcinog. | pmid:27753148 |
Shi X et al. | Comparison of the in vitro metabolism of psoralidin among different species and characterization of its inhibitory effect against UDP- glucuronosyltransferase (UGT) or cytochrome p450 (CYP450) enzymes. | 2016 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:27428458 |
Ren G et al. | Psoralidin induced reactive oxygen species (ROS)-dependent DNA damage and protective autophagy mediated by NOX4 in breast cancer cells. | 2016 | Phytomedicine | pmid:27387402 |