Psoralidin

Psoralidin is a lipid of Polyketides (PK) class. Psoralidin is associated with abnormalities such as Infection, Vitiligo, Psoriasis, Morphologically altered structure and Cyst. The involved functions are known as Signal Transduction, Apoptosis, DNA Binding, Ectopic Expression and kinase activity. Psoralidin often locates in Cytoplasmic matrix, Cytoplasmic, Body tissue, Cytoplasm and Cell membrane. The associated genes with Psoralidin are MSMP gene, BCL2 gene, PDZD2 gene, PKD2 gene and SART3 gene. The related experimental models are Xenograft Model.

Cross Reference

Introduction

To understand associated biological information of Psoralidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Psoralidin?

Psoralidin is suspected in Morphologically altered structure, Cyst, Infection, Vitiligo, Psoriasis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Psoralidin

MeSH term MeSH ID Detail
Prostatic Neoplasms D011471 126 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Psoralidin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Psoralidin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Psoralidin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Psoralidin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Psoralidin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Psoralidin?

Xenograft Model

Xenograft Model are used in the study 'Activating stress-activated protein kinase-mediated cell death and inhibiting epidermal growth factor receptor signaling: a promising therapeutic strategy for prostate cancer.' (Kumar R et al., 2010).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Psoralidin

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Authors Title Published Journal PubMed Link
Alalaiwe A et al. The active compounds derived from Psoralea corylifolia for photochemotherapy against psoriasis-like lesions: The relationship between structure and percutaneous absorption. 2018 Eur J Pharm Sci pmid:30153523
Zhai Y et al. The higher osteoprotective activity of psoralidin in vivo than coumestrol is attributed by its presence of an isopentenyl group and through activated PI3K/Akt axis. 2018 Biomed. Pharmacother. pmid:29710518
Rao Z et al. Protective effects of psoralidin on IL‑1β‑induced chondrocyte apoptosis. 2018 Mol Med Rep pmid:29257269
Kong L et al. Psoralidin suppresses osteoclastogenesis in BMMs and attenuates LPS-mediated osteolysis by inhibiting inflammatory cytokines. 2017 Int. Immunopharmacol. pmid:28779592
Chen CH et al. Isoflavones and anti-inflammatory constituents from the fruits of Psoralea corylifolia. 2017 Phytochemistry pmid:28825980
Pal D et al. Inhibition of autophagy prevents cadmium-induced prostate carcinogenesis. 2017 Br. J. Cancer pmid:28588318
Zhai Y et al. Psoralidin, a prenylated coumestan, as a novel anti-osteoporosis candidate to enhance bone formation of osteoblasts and decrease bone resorption of osteoclasts. 2017 Eur. J. Pharmacol. pmid:28283388
Pal D et al. Targeting aberrant expression of Notch-1 in ALDH cancer stem cells in breast cancer. 2017 Mol. Carcinog. pmid:27753148
Shi X et al. Comparison of the in vitro metabolism of psoralidin among different species and characterization of its inhibitory effect against UDP- glucuronosyltransferase (UGT) or cytochrome p450 (CYP450) enzymes. 2016 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:27428458
Ren G et al. Psoralidin induced reactive oxygen species (ROS)-dependent DNA damage and protective autophagy mediated by NOX4 in breast cancer cells. 2016 Phytomedicine pmid:27387402