Psoralidin

Psoralidin is a lipid of Polyketides (PK) class. Psoralidin is associated with abnormalities such as Infection, Vitiligo, Psoriasis, Morphologically altered structure and Cyst. The involved functions are known as Signal Transduction, Apoptosis, DNA Binding, Ectopic Expression and kinase activity. Psoralidin often locates in Cytoplasmic matrix, Cytoplasmic, Body tissue, Cytoplasm and Cell membrane. The associated genes with Psoralidin are MSMP gene, BCL2 gene, PDZD2 gene, PKD2 gene and SART3 gene. The related experimental models are Xenograft Model.

Cross Reference

Introduction

To understand associated biological information of Psoralidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Psoralidin?

Psoralidin is suspected in Morphologically altered structure, Cyst, Infection, Vitiligo, Psoriasis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Psoralidin

MeSH term MeSH ID Detail
Prostatic Neoplasms D011471 126 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Psoralidin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Psoralidin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Psoralidin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Psoralidin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Psoralidin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Psoralidin?

Xenograft Model

Xenograft Model are used in the study 'Activating stress-activated protein kinase-mediated cell death and inhibiting epidermal growth factor receptor signaling: a promising therapeutic strategy for prostate cancer.' (Kumar R et al., 2010).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Psoralidin

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Authors Title Published Journal PubMed Link
Chiou WF et al. Psoralidin inhibits LPS-induced iNOS expression via repressing Syk-mediated activation of PI3K-IKK-IκB signaling pathways. 2011 Eur. J. Pharmacol. pmid:20951127
Qiu RL et al. [Study on the chemical constituents of Psoralea corylifolia]. 2011 Zhong Yao Cai pmid:22233033
Wang Y et al. Screening Antitumor Compounds Psoralen and Isopsoralen from Psoralea corylifolia L. Seeds. 2011 Evid Based Complement Alternat Med pmid:19131395
Retraction. Psoralidin, an herbal molecule, inhibits phosphatidylinositol 3-kinase-mediated Akt signaling in androgen-independent prostate cancer cells. 2011 Cancer Prev Res (Phila) pmid:22025547
Szliszka E et al. Enhanced TRAIL-mediated apoptosis in prostate cancer cells by the bioactive compounds neobavaisoflavone and psoralidin isolated from Psoralea corylifolia. 2011 Pharmacol Rep pmid:21441621
Kumar R et al. Activating stress-activated protein kinase-mediated cell death and inhibiting epidermal growth factor receptor signaling: a promising therapeutic strategy for prostate cancer. 2010 Mol. Cancer Ther. pmid:20736346
Srinivasan S et al. Inhibiting TNF-mediated signaling: a novel therapeutic paradigm for androgen independent prostate cancer. 2010 Apoptosis pmid:19851870
Xiao G et al. Isolation of antioxidants from Psoralea corylifolia fruits using high-speed counter-current chromatography guided by thin layer chromatography-antioxidant autographic assay. 2010 J Chromatogr A pmid:20663508
Khushboo PS et al. Psoralea corylifolia Linn.-"Kushtanashini". 2010 Pharmacogn Rev pmid:22228944
Pahari P and Rohr J Total synthesis of psoralidin, an anticancer natural product. 2009 J. Org. Chem. pmid:19254011