MeSH term | MeSH ID | Detail |
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Prostatic Neoplasms | D011471 | 126 associated lipids |
Psoralidin is a lipid of Polyketides (PK) class. Psoralidin is associated with abnormalities such as Infection, Vitiligo, Psoriasis, Morphologically altered structure and Cyst. The involved functions are known as Signal Transduction, Apoptosis, DNA Binding, Ectopic Expression and kinase activity. Psoralidin often locates in Cytoplasmic matrix, Cytoplasmic, Body tissue, Cytoplasm and Cell membrane. The associated genes with Psoralidin are MSMP gene, BCL2 gene, PDZD2 gene, PKD2 gene and SART3 gene. The related experimental models are Xenograft Model.
To understand associated biological information of Psoralidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Psoralidin is suspected in Morphologically altered structure, Cyst, Infection, Vitiligo, Psoriasis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Psoralidin
MeSH term | MeSH ID | Detail |
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Prostatic Neoplasms | D011471 | 126 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Xenograft Model are used in the study 'Activating stress-activated protein kinase-mediated cell death and inhibiting epidermal growth factor receptor signaling: a promising therapeutic strategy for prostate cancer.' (Kumar R et al., 2010).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Chiou WF et al. | Psoralidin inhibits LPS-induced iNOS expression via repressing Syk-mediated activation of PI3K-IKK-IκB signaling pathways. | 2011 | Eur. J. Pharmacol. | pmid:20951127 |
Qiu RL et al. | [Study on the chemical constituents of Psoralea corylifolia]. | 2011 | Zhong Yao Cai | pmid:22233033 |
Wang Y et al. | Screening Antitumor Compounds Psoralen and Isopsoralen from Psoralea corylifolia L. Seeds. | 2011 | Evid Based Complement Alternat Med | pmid:19131395 |
Retraction. Psoralidin, an herbal molecule, inhibits phosphatidylinositol 3-kinase-mediated Akt signaling in androgen-independent prostate cancer cells. | 2011 | Cancer Prev Res (Phila) | pmid:22025547 | |
Szliszka E et al. | Enhanced TRAIL-mediated apoptosis in prostate cancer cells by the bioactive compounds neobavaisoflavone and psoralidin isolated from Psoralea corylifolia. | 2011 | Pharmacol Rep | pmid:21441621 |
Kumar R et al. | Activating stress-activated protein kinase-mediated cell death and inhibiting epidermal growth factor receptor signaling: a promising therapeutic strategy for prostate cancer. | 2010 | Mol. Cancer Ther. | pmid:20736346 |
Srinivasan S et al. | Inhibiting TNF-mediated signaling: a novel therapeutic paradigm for androgen independent prostate cancer. | 2010 | Apoptosis | pmid:19851870 |
Xiao G et al. | Isolation of antioxidants from Psoralea corylifolia fruits using high-speed counter-current chromatography guided by thin layer chromatography-antioxidant autographic assay. | 2010 | J Chromatogr A | pmid:20663508 |
Khushboo PS et al. | Psoralea corylifolia Linn.-"Kushtanashini". | 2010 | Pharmacogn Rev | pmid:22228944 |
Pahari P and Rohr J | Total synthesis of psoralidin, an anticancer natural product. | 2009 | J. Org. Chem. | pmid:19254011 |