COUMESTROL

COUMESTROL is a lipid of Polyketides (PK) class. Coumestrol is associated with abnormalities such as Infertility, Renal tubular disorder, Osteoporosis, Postmenopausal, Nodule and Central precocious puberty. The involved functions are known as Process, antagonists, Accident due to exposure to weather conditions, physiological aspects and Cell Proliferation. Coumestrol often locates in Blood, Body tissue, Reproductive system, Membrane and Myometrial. The associated genes with COUMESTROL are GAPDH gene, PPID gene, pyridinoline, NODAL gene and Nitrogen fixation gene. The related lipids are enterodiol. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of COUMESTROL, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with COUMESTROL?

COUMESTROL is suspected in Infertility, Renal tubular disorder, Osteoporosis, Postmenopausal, Nodule, Central precocious puberty and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with COUMESTROL

MeSH term MeSH ID Detail
Breast Neoplasms D001943 24 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Weight Gain D015430 101 associated lipids
Endometriosis D004715 29 associated lipids
Birth Weight D001724 23 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with COUMESTROL

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with COUMESTROL?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with COUMESTROL?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with COUMESTROL?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with COUMESTROL?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with COUMESTROL?

Mouse Model

Mouse Model are used in the study 'Modulation of tumor formation and intestinal cell migration by estrogens in the Apc(Min/+) mouse model of colorectal cancer.' (Javid SH et al., 2005).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with COUMESTROL

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Authors Title Published Journal PubMed Link
CAYEN MN and COMMON RH AN INVESTIGATION OF URINARY CONVERSION PRODUCTS OF COUMESTROL IN THE FOWL. 1965 Biochim. Biophys. Acta pmid:14347952
BICKOFF EM et al. ISOLATION OF COUMESTROL AND OTHER PHENOLICS FROM ALFALFA BY COUNTERCURRENT DISTRIBUTION. 1964 J Pharm Sci pmid:14255129
NOTEBOOM WD and GORSKI J ESTROGENIC EFFECTS OF GENISTEIN AND COUMESTROL DIACETATE. 1963 Endocrinology pmid:14089631
BICKOFF EM et al. Estrogenic activity of coumestrol and related compounds. 1960 Arch. Biochem. Biophys. pmid:13800504
BICKOFF EM et al. Coumestrol, a new estrogen isolated from forage crops. 1957 Science pmid:13486041
pmid:6470421
pmid:
McMurry CS and Dickerson RL Effects of binary mixtures of six xenobiotics on hormone concentrations and morphometric endpoints of northern bobwhite quail (Colinus virginianus). Chemosphere pmid:11372873