HEMATOXYLIN is a lipid of Polyketides (PK) class. Hematoxylin is associated with abnormalities such as Eosinophilia, Duodenal Adenoma, Senile Plaques, Morphologically altered structure and Cervical abscess. The involved functions are known as Uptake, Apoptosis, Amplification, Necrosis and Karyopyknosis. Hematoxylin often locates in Body tissue, Extracellular, Compact bone, Skin and Basement membrane. The associated genes with HEMATOXYLIN are GAPDH gene, Genome, Elastin, MERTK wt Allele and P4HTM gene.
To understand associated biological information of HEMATOXYLIN, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
HEMATOXYLIN is suspected in Senile Plaques, Eosinophilia, Duodenal Adenoma, Morphologically altered structure, Cervical abscess and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with HEMATOXYLIN
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Liu WM et al. | Inhibition of metastatic potential in colorectal carcinoma in vivo and in vitro using immunomodulatory drugs (IMiDs). | 2009 | Br. J. Cancer | pmid:19638977 |
Mellado B et al. | Phase II trial of short-term neoadjuvant docetaxel and complete androgen blockade in high-risk prostate cancer. | 2009 | Br. J. Cancer | pmid:19755998 |
Eichenmüller M et al. | Betulinic acid induces apoptosis and inhibits hedgehog signalling in rhabdomyosarcoma. | 2010 | Br. J. Cancer | pmid:20517313 |
Nakagawa S et al. | Analysis of the expression and localisation of a LAP protein, human scribble, in the normal and neoplastic epithelium of uterine cervix. | 2004 | Br. J. Cancer | pmid:14710229 |
Hamma-Kourbali Y et al. | Carboxymethyl benzylamide dextran inhibits angiogenesis and growth of VEGF-overexpressing human epidermoid carcinoma xenograft in nude mice. | 2003 | Br. J. Cancer | pmid:12838326 |
Brownhill SC et al. | Chromosome 9p21 gene copy number and prognostic significance of p16 in ESFT. | 2007 | Br. J. Cancer | pmid:17533400 |
Yao H et al. | Expression of FAP-1 by human colon adenocarcinoma: implication for resistance against Fas-mediated apoptosis in cancer. | 2004 | Br. J. Cancer | pmid:15494722 |
Pardo FS et al. | Mutant, wild type, or overall p53 expression: freedom from clinical progression in tumours of astrocytic lineage. | 2004 | Br. J. Cancer | pmid:15494720 |
Kristiansen G et al. | CD24 is an independent prognostic marker of survival in nonsmall cell lung cancer patients. | 2003 | Br. J. Cancer | pmid:12610508 |
Abd El-Rehim DM et al. | Expression and co-expression of the members of the epidermal growth factor receptor (EGFR) family in invasive breast carcinoma. | 2004 | Br. J. Cancer | pmid:15480434 |
Hussain SA et al. | Proapoptotic genes BAX and CD40L are predictors of survival in transitional cell carcinoma of the bladder. | 2003 | Br. J. Cancer | pmid:12592374 |
Spizzo G et al. | Correlation of COX-2 and Ep-CAM overexpression in human invasive breast cancer and its impact on survival. | 2003 | Br. J. Cancer | pmid:12592372 |
Pelosi G et al. | Independent prognostic value of fascin immunoreactivity in stage I nonsmall cell lung cancer. | 2003 | Br. J. Cancer | pmid:12592367 |
Unoki M et al. | UHRF1 is a novel diagnostic marker of lung cancer. | 2010 | Br. J. Cancer | pmid:20517312 |
Millar EK et al. | BAG-1 predicts patient outcome and tamoxifen responsiveness in ER-positive invasive ductal carcinoma of the breast. | 2009 | Br. J. Cancer | pmid:19066611 |
Pamecha V et al. | Effect of portal vein embolisation on the growth rate of colorectal liver metastases. | 2009 | Br. J. Cancer | pmid:19209170 |
Li Q et al. | Expression of interferon-gamma in human adrenal gland and kidney tumours. | 2007 | Br. J. Cancer | pmid:17622250 |
Nishikawa M et al. | Accumulation of mitochondrial DNA mutation with colorectal carcinogenesis in ulcerative colitis. | 2005 | Br. J. Cancer | pmid:15956973 |
Clark SE et al. | Molecular subtyping of DCIS: heterogeneity of breast cancer reflected in pre-invasive disease. | 2011 | Br. J. Cancer | pmid:21139586 |
Onda M et al. | Decreased expression of haemoglobin beta (HBB) gene in anaplastic thyroid cancer and recovery of its expression inhibits cell growth. | 2005 | Br. J. Cancer | pmid:15956966 |
Ni X et al. | Characterisation of human kallikrein 6/protease M expression in ovarian cancer. | 2004 | Br. J. Cancer | pmid:15305183 |
Fareed KR et al. | Tumour regression and ERCC1 nuclear protein expression predict clinical outcome in patients with gastro-oesophageal cancer treated with neoadjuvant chemotherapy. | 2010 | Br. J. Cancer | pmid:20461087 |
Sersa G et al. | Reduced blood flow and oxygenation in SA-1 tumours after electrochemotherapy with cisplatin. | 2002 | Br. J. Cancer | pmid:12434299 |
Fan LZ and Cherian MG | Potential role of p53 on metallothionein induction in human epithelial breast cancer cells. | 2002 | Br. J. Cancer | pmid:12434295 |
Bibi R et al. | A specific cadherin phenotype may characterise the disseminating yet non-metastatic behaviour of pseudomyxoma peritonei. | 2006 | Br. J. Cancer | pmid:17031402 |
Thews O et al. | Microenvironmental adaptation of experimental tumours to chronic vs acute hypoxia. | 2004 | Br. J. Cancer | pmid:15305198 |
Bruland O et al. | Gene expression reveals two distinct groups of anal carcinomas with clinical implications. | 2008 | Br. J. Cancer | pmid:18349847 |
Puppa G et al. | Independent prognostic value of fascin immunoreactivity in stage III-IV colonic adenocarcinoma. | 2007 | Br. J. Cancer | pmid:17375048 |
Schmitz M et al. | Identification of SOX2 as a novel glioma-associated antigen and potential target for T cell-based immunotherapy. | 2007 | Br. J. Cancer | pmid:17375044 |
Comstock CE et al. | Impact of differential cyclin D1 expression and localisation in prostate cancer. | 2007 | Br. J. Cancer | pmid:17375037 |
Elie C et al. | Lack of relationship between EGFR-1 immunohistochemical expression and prognosis in a multicentre clinical trial of 93 patients with advanced primary ovarian epithelial cancer (GINECO group). | 2004 | Br. J. Cancer | pmid:15226774 |
Ogawa E et al. | Clinical significance of VEGF-C status in tumour cells and stromal macrophages in non-small cell lung cancer patients. | 2004 | Br. J. Cancer | pmid:15226767 |
Collet JF et al. | Galectin-3 immunodetection in follicular thyroid neoplasms: a prospective study on fine-needle aspiration samples. | 2005 | Br. J. Cancer | pmid:16251880 |
Koljonen V et al. | Chronic lymphocytic leukaemia patients have a high risk of Merkel-cell polyomavirus DNA-positive Merkel-cell carcinoma. | 2009 | Br. J. Cancer | pmid:19755994 |
Shehata M et al. | Human leukocyte antigen class I expression is an independent prognostic factor in advanced ovarian cancer resistant to first-line platinum chemotherapy. | 2009 | Br. J. Cancer | pmid:19755991 |
Lugli A et al. | CD8+ lymphocytes/ tumour-budding index: an independent prognostic factor representing a 'pro-/anti-tumour' approach to tumour host interaction in colorectal cancer. | 2009 | Br. J. Cancer | pmid:19755986 |
Angst E et al. | Cellular differentiation determines the expression of the hypoxia-inducible protein NDRG1 in pancreatic cancer. | 2006 | Br. J. Cancer | pmid:16832411 |
Chen YL et al. | Granulocytes mediates the Fas-L-associated apoptosis during lung metastasis of melanoma that determines the metastatic behaviour. | 2002 | Br. J. Cancer | pmid:12177809 |
Baeten CI et al. | Flow cytometric quantification of tumour endothelial cells; an objective alternative for microvessel density assessment. | 2002 | Br. J. Cancer | pmid:12177806 |
Sheridan J et al. | Nuclear oxidative damage correlates with poor survival in colorectal cancer. | 2009 | Br. J. Cancer | pmid:19066606 |
Ameri K et al. | Circulating tumour cells demonstrate an altered response to hypoxia and an aggressive phenotype. | 2010 | Br. J. Cancer | pmid:20051957 |
van Beers EH et al. | A multiplex PCR predictor for aCGH success of FFPE samples. | 2006 | Br. J. Cancer | pmid:16333309 |
Ding SL et al. | Abnormality of the DNA double-strand-break checkpoint/repair genes, ATM, BRCA1 and TP53, in breast cancer is related to tumour grade. | 2004 | Br. J. Cancer | pmid:15138484 |
Patmore HS et al. | Can a genetic signature for metastatic head and neck squamous cell carcinoma be characterised by comparative genomic hybridisation? | 2004 | Br. J. Cancer | pmid:15138481 |
McCallum M et al. | A prognostic index for operable, node-negative breast cancer. | 2004 | Br. J. Cancer | pmid:15138474 |
Matsuyoshi S et al. | FADD phosphorylation is critical for cell cycle regulation in breast cancer cells. | 2006 | Br. J. Cancer | pmid:16450001 |
Sivridis E et al. | Thymidine phosphorylase expression in normal, hyperplastic and neoplastic prostates: correlation with tumour associated macrophages, infiltrating lymphocytes, and angiogenesis. | 2002 | Br. J. Cancer | pmid:11986782 |
Hildenbrand R and Arens N | Protein and mRNA expression of uPAR and PAI-1 in myoepithelial cells of early breast cancer lesions and normal breast tissue. | 2004 | Br. J. Cancer | pmid:15226768 |
Ueno Y et al. | Selective inhibition of TNF-alpha-induced activation of mitogen-activated protein kinases and metastatic activities by gefitinib. | 2005 | Br. J. Cancer | pmid:15841081 |
Sriraksa R et al. | CpG-island methylation study of liver fluke-related cholangiocarcinoma. | 2011 | Br. J. Cancer | pmid:21448164 |
Kato T et al. | A quantitative analysis of lymphatic vessels in human breast cancer, based on LYVE-1 immunoreactivity. | 2005 | Br. J. Cancer | pmid:16251871 |
Dai DL et al. | Reduced Apaf-1 expression in human cutaneous melanomas. | 2004 | Br. J. Cancer | pmid:15305193 |
Hussain SA et al. | Hypoxia-regulated carbonic anhydrase IX expression is associated with poor survival in patients with invasive breast cancer. | 2007 | Br. J. Cancer | pmid:17213826 |
Hosono S et al. | Expression of Twist increases the risk for recurrence and for poor survival in epithelial ovarian carcinoma patients. | 2007 | Br. J. Cancer | pmid:17211477 |
Grützmann R et al. | ADAM9 expression in pancreatic cancer is associated with tumour type and is a prognostic factor in ductal adenocarcinoma. | 2004 | Br. J. Cancer | pmid:14997207 |
Vicent S et al. | ERK1/2 is activated in non-small-cell lung cancer and associated with advanced tumours. | 2004 | Br. J. Cancer | pmid:14997206 |
Takemoto S et al. | Expression of activated signal transducer and activator of transcription-3 predicts poor prognosis in cervical squamous-cell carcinoma. | 2009 | Br. J. Cancer | pmid:19638983 |
Lagadec P et al. | Pharmacological targeting of NF-kappaB potentiates the effect of the topoisomerase inhibitor CPT-11 on colon cancer cells. | 2008 | Br. J. Cancer | pmid:18182997 |
Awwad HK et al. | Accelerated hyperfractionation (AHF) compared to conventional fractionation (CF) in the postoperative radiotherapy of locally advanced head and neck cancer: influence of proliferation. | 2002 | Br. J. Cancer | pmid:11870530 |
Mitra A et al. | Prostate cancer in male BRCA1 and BRCA2 mutation carriers has a more aggressive phenotype. | 2008 | Br. J. Cancer | pmid:18182994 |
Rofstad EK and Halsør EF | Hypoxia-associated spontaneous pulmonary metastasis in human melanoma xenografts: involvement of microvascular hot spots induced in hypoxic foci by interleukin 8. | 2002 | Br. J. Cancer | pmid:11870523 |
Cheng Q et al. | Identification of molecular markers for the early detection of human squamous cell carcinoma of the uterine cervix. | 2002 | Br. J. Cancer | pmid:11870519 |
Brooks LA et al. | E7 proteins from oncogenic human papillomavirus types transactivate p73: role in cervical intraepithelial neoplasia. | 2002 | Br. J. Cancer | pmid:11870517 |
Watermann DO et al. | Specific induction of pp125 focal adhesion kinase in human breast cancer. | 2005 | Br. J. Cancer | pmid:16136050 |
Beresford MJ et al. | The relationship of the neo-angiogenic marker, endoglin, with response to neoadjuvant chemotherapy in breast cancer. | 2006 | Br. J. Cancer | pmid:17160082 |
Ito Y et al. | Polo-like kinase 1 overexpression is an early event in the progression of papillary carcinoma. | 2004 | Br. J. Cancer | pmid:14735186 |
Prowatke I et al. | Expression analysis of imbalanced genes in prostate carcinoma using tissue microarrays. | 2007 | Br. J. Cancer | pmid:17146477 |
Myers E et al. | Inverse relationship between ER-beta and SRC-1 predicts outcome in endocrine-resistant breast cancer. | 2004 | Br. J. Cancer | pmid:15477868 |
Kostourou V et al. | The role of tumour-derived iNOS in tumour progression and angiogenesis. | 2011 | Br. J. Cancer | pmid:21139581 |
Wu CF et al. | Expression of parvin-beta is a prognostic factor for patients with urothelial cell carcinoma of the upper urinary tract. | 2010 | Br. J. Cancer | pmid:20736946 |
Rachagani S et al. | Activated KrasG¹²D is associated with invasion and metastasis of pancreatic cancer cells through inhibition of E-cadherin. | 2011 | Br. J. Cancer | pmid:21364589 |
Cui T et al. | DSC3 expression is regulated by p53, and methylation of DSC3 DNA is a prognostic marker in human colorectal cancer. | 2011 | Br. J. Cancer | pmid:21364582 |
Verschoyle RD et al. | Evaluation of the cancer chemopreventive efficacy of rice bran in genetic mouse models of breast, prostate and intestinal carcinogenesis. | 2007 | Br. J. Cancer | pmid:17211473 |
Knijn N et al. | KRAS mutation analysis: a comparison between primary tumours and matched liver metastases in 305 colorectal cancer patients. | 2011 | Br. J. Cancer | pmid:21364579 |
Cocco E et al. | Serum amyloid A (SAA): a novel biomarker for uterine serous papillary cancer. | 2009 | Br. J. Cancer | pmid:19536090 |
Dangles V et al. | Gene expression profiles of bladder cancers: evidence for a striking effect of in vitro cell models on gene patterns. | 2002 | Br. J. Cancer | pmid:11953886 |
Staibano S et al. | OPN/CD44v6 overexpression in laryngeal dysplasia and correlation with clinical outcome. | 2007 | Br. J. Cancer | pmid:17987038 |
Mellor P et al. | Modulatory effects of heparin and short-length oligosaccharides of heparin on the metastasis and growth of LMD MDA-MB 231 breast cancer cells in vivo. | 2007 | Br. J. Cancer | pmid:17726466 |
Yamamoto E et al. | Expression of N-acetylglucosaminyltransferase V in endometrial cancer correlates with poor prognosis. | 2007 | Br. J. Cancer | pmid:17971775 |
Jenkinson SR et al. | S100A4 regulates cell motility and invasion in an in vitro model for breast cancer metastasis. | 2004 | Br. J. Cancer | pmid:14710237 |
Jacques C et al. | Death-associated protein 3 is overexpressed in human thyroid oncocytic tumours. | 2009 | Br. J. Cancer | pmid:19536094 |
Carpenter B et al. | Heterogeneous nuclear ribonucleoprotein K is over expressed, aberrantly localised and is associated with poor prognosis in colorectal cancer. | 2006 | Br. J. Cancer | pmid:16953238 |
Ugurel S et al. | Lack of clinical efficacy of imatinib in metastatic melanoma. | 2005 | Br. J. Cancer | pmid:15846297 |
Brown NS et al. | Cooperative stimulation of vascular endothelial growth factor expression by hypoxia and reactive oxygen species: the effect of targeting vascular endothelial growth factor and oxidative stress in an orthotopic xenograft model of bladder carcinoma. | 2005 | Br. J. Cancer | pmid:15841086 |
Chatrath P et al. | Aberrant expression of minichromosome maintenance protein-2 and Ki67 in laryngeal squamous epithelial lesions. | 2003 | Br. J. Cancer | pmid:12966424 |
Langbein S et al. | Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted. | 2006 | Br. J. Cancer | pmid:16465194 |
Kurokawa T et al. | Overexpression of hypoxia-inducible-factor 1alpha(HIF-1alpha) in oesophageal squamous cell carcinoma correlates with lymph node metastasis and pathologic stage. | 2003 | Br. J. Cancer | pmid:12966423 |
Hudelist G et al. | Her-2/neu-triggered intracellular tyrosine kinase activation: in vivo relevance of ligand-independent activation mechanisms and impact upon the efficacy of trastuzumab-based treatment. | 2003 | Br. J. Cancer | pmid:12966413 |
Larsson A et al. | Overexpression of podocalyxin-like protein is an independent factor of poor prognosis in colorectal cancer. | 2011 | Br. J. Cancer | pmid:21829192 |
Hartana CA et al. | Detection of micrometastases by flow cytometry in sentinel lymph nodes from patients with renal tumours. | 2016 | Br. J. Cancer | pmid:27599044 |
Lawrie LC et al. | Liver fatty acid binding protein expression in colorectal neoplasia. | 2004 | Br. J. Cancer | pmid:15138477 |
Fondevila C et al. | p53 and VEGF expression are independent predictors of tumour recurrence and survival following curative resection of gastric cancer. | 2004 | Br. J. Cancer | pmid:14710231 |
Hashida H et al. | Clinical significance of transmembrane 4 superfamily in colon cancer. | 2003 | Br. J. Cancer | pmid:12838318 |
Yamamoto T et al. | No major tumorigenic role for beta-catenin in serrated as opposed to conventional colorectal adenomas. | 2003 | Br. J. Cancer | pmid:12838317 |
Sersa G et al. | Vascular disrupting action of electroporation and electrochemotherapy with bleomycin in murine sarcoma. | 2008 | Br. J. Cancer | pmid:18182988 |
Shyu RY et al. | RARRES3 expression positively correlated to tumour differentiation in tissues of colorectal adenocarcinoma. | 2003 | Br. J. Cancer | pmid:12838316 |
Xue SA et al. | Epstein-Barr virus gene expression in human breast cancer: protagonist or passenger? | 2003 | Br. J. Cancer | pmid:12838311 |
Benharroch D et al. | Measles virus: evidence of an association with Hodgkin's disease. | 2004 | Br. J. Cancer | pmid:15226778 |
de Graeff P et al. | The ErbB signalling pathway: protein expression and prognostic value in epithelial ovarian cancer. | 2008 | Br. J. Cancer | pmid:18628764 |
Southern SA et al. | Induction of tetrasomy by human papillomavirus type 16 E7 protein is independent of pRb binding and disruption of differentiation. | 2004 | Br. J. Cancer | pmid:15138476 |