15-deoxy-delta-12,14-PGJ2

15-deoxy-delta-12,14-pgj2 is a lipid of Fatty Acyls (FA) class. 15-deoxy-delta-12,14-pgj2 is associated with abnormalities such as Dehydration and Myocardial Ischemia. The involved functions are known as Binding (Molecular Function), Inflammation, Alveolar ventilation function, Stimulus and Process. 15-deoxy-delta-12,14-pgj2 often locates in Cytosol, Myocardial tissue and Heart tissue. The associated genes with 15-deoxy-delta-12,14-PGJ2 are Homologous Gene and G-substrate. The related lipids are 15-deoxyprostaglandin J2 and Lipopolysaccharides.

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Introduction

To understand associated biological information of 15-deoxy-delta-12,14-PGJ2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 15-deoxy-delta-12,14-PGJ2?

15-deoxy-delta-12,14-PGJ2 is suspected in Dehydration, Myocardial Ischemia and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 15-deoxy-delta-12,14-PGJ2

PubChem Associated disorders and diseases

What pathways are associated with 15-deoxy-delta-12,14-PGJ2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 15-deoxy-delta-12,14-PGJ2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 15-deoxy-delta-12,14-PGJ2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 15-deoxy-delta-12,14-PGJ2?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 15-deoxy-delta-12,14-PGJ2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 15-deoxy-delta-12,14-PGJ2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 15-deoxy-delta-12,14-PGJ2

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Authors Title Published Journal PubMed Link
Paakinaho V et al. Electrophilic lipid mediator 15-deoxy-Δ12,14-prostaglandin j2 modifies glucocorticoid signaling via receptor SUMOylation. 2014 Mol. Cell. Biol. pmid:24980431
Koyani CN et al. 15-deoxy-Δ¹²,¹⁴-PGJ₂ promotes inflammation and apoptosis in cardiomyocytes via the DP2/MAPK/TNFα axis. 2014 Int. J. Cardiol. pmid:24698234
Wang C et al. A chemoproteomic platform to quantitatively map targets of lipid-derived electrophiles. 2014 Nat. Methods pmid:24292485
García-Bueno B et al. Pro-/anti-inflammatory dysregulation in patients with first episode of psychosis: toward an integrative inflammatory hypothesis of schizophrenia. 2014 Schizophr Bull pmid:23486748
Katsumata Y et al. Endogenous prostaglandin D2 and its metabolites protect the heart against ischemia-reperfusion injury by activating Nrf2. 2014 Hypertension pmid:24101662
Casali CI et al. Coordinate regulation between the nuclear receptor peroxisome proliferator-activated receptor-γ and cyclooxygenase-2 in renal epithelial cells. 2014 Biochem. Pharmacol. pmid:24915420
Chen S et al. 15-Deoxy-Δ(12,14)-prostaglandin J2 (15d-PGJ2) promotes apoptosis of HBx-positive liver cells. 2014 Chem. Biol. Interact. pmid:24582817
Hau CS et al. Suppressive effects of antimycotics on thymic stromal lymphopoietin production in human keratinocytes. 2013 J. Dermatol. Sci. pmid:23688403
Haskew-Layton RE et al. 15-Deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2) protects neurons from oxidative death via an Nrf2 astrocyte-specific mechanism independent of PPARγ. 2013 J. Neurochem. pmid:23199167
Kaikkonen S et al. Prostaglandin 15d-PGJ(2) inhibits androgen receptor signaling in prostate cancer cells. 2013 Mol. Endocrinol. pmid:23192983