Hispidulin

Hispidulin is a lipid of Polyketides (PK) class. Hispidulin is associated with abnormalities such as Chagas Disease and Leishmania mexicana disease. The involved functions are known as Metabolic Inhibition.

Cross Reference

Introduction

To understand associated biological information of Hispidulin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Hispidulin?

Hispidulin is suspected in Leishmania mexicana disease, Chagas Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Hispidulin

MeSH term MeSH ID Detail
Prostatic Neoplasms D011471 126 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Glioblastoma D005909 27 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Hispidulin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Hispidulin?

There are no associated biomedical information in the current reference collection.

What functions are associated with Hispidulin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Hispidulin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Hispidulin?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Hispidulin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Hispidulin

Download all related citations
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Authors Title Published Journal PubMed Link
Lee SG et al. Hispidulin inhibits adipogenesis in 3T3-L1 adipocytes through PPARγ pathway. 2018 Chem. Biol. Interact. pmid:30055130
Liu K et al. Hispidulin suppresses cell growth and metastasis by targeting PIM1 through JAK2/STAT3 signaling in colorectal cancer. 2018 Cancer Sci. pmid:29575334
Huang L et al. Hispidulin prevents sevoflurane- Induced memory dysfunction in aged rats. 2018 Biomed. Pharmacother. pmid:29091891
Shakeri A et al. Screening of several biological activities induced by different sesquiterpene lactones isolated from Centaurea behen L. and Rhaponticum repens (L.) Hidalgo. 2018 Nat. Prod. Res. pmid:28641489
An P et al. Hispidulin Protects Against Focal Cerebral Ischemia Reperfusion Injury in Rats. 2018 J. Mol. Neurosci. pmid:29799104
Wu F et al. Hispidulin alleviates high-glucose-induced podocyte injury by regulating protective autophagy. 2018 Biomed. Pharmacother. pmid:29775899
Han M et al. Hispidulin inhibits hepatocellular carcinoma growth and metastasis through AMPK and ERK signaling mediated activation of PPARγ. 2018 Biomed. Pharmacother. pmid:29656183
Huang L et al. Autophagy induction by hispidulin provides protection against sevoflurane-induced neuronal apoptosis in aged rats. 2018 Biomed. Pharmacother. pmid:29287193
Gao H et al. Hispidulin mediates apoptosis in human renal cell carcinoma by inducing ceramide accumulation. 2017 Acta Pharmacol. Sin. pmid:29119970
Lee YK et al. Inhibitory Effect of Chemical Constituents Isolated from on Polyol Pathway and Simultaneous Quantification of Major Bioactive Compounds. 2017 Biomed Res Int pmid:28512639