Hispidulin

Hispidulin is a lipid of Polyketides (PK) class. Hispidulin is associated with abnormalities such as Chagas Disease and Leishmania mexicana disease. The involved functions are known as Metabolic Inhibition.

Cross Reference

Introduction

To understand associated biological information of Hispidulin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Hispidulin?

Hispidulin is suspected in Leishmania mexicana disease, Chagas Disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Hispidulin

MeSH term MeSH ID Detail
Prostatic Neoplasms D011471 126 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Glioblastoma D005909 27 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with Hispidulin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Hispidulin?

There are no associated biomedical information in the current reference collection.

What functions are associated with Hispidulin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Hispidulin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Hispidulin?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Hispidulin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Hispidulin

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Authors Title Published Journal PubMed Link
Srisook K et al. Bioassay-guided isolation and mechanistic action of anti-inflammatory agents from Clerodendrum inerme leaves. 2015 J Ethnopharmacol pmid:25725433
Fan Y et al. Bioactive compounds of Eriocaulon sieboldianum blocking proliferation and inducing apoptosis of HepG2 cells might be involved in Aurora kinase inhibition. 2015 Food Funct pmid:26369427
Chao SW et al. Total Synthesis of Hispidulin and the Structural Basis for Its Inhibition of Proto-oncogene Kinase Pim-1. 2015 J. Nat. Prod. pmid:26275107
Scoparo CT et al. Dual properties of hispidulin: antiproliferative effects on HepG2 cancer cells and selective inhibition of ABCG2 transport activity. 2015 Mol. Cell. Biochem. pmid:26209062
Huang WJ et al. Hispidulin, a constituent of Clerodendrum inerme that remitted motor tics, alleviated methamphetamine-induced hyperlocomotion without motor impairment in mice. 2015 J Ethnopharmacol pmid:25764963
Lin TY et al. Protective effect of hispidulin on kainic acid-induced seizures and neurotoxicity in rats. 2015 Eur. J. Pharmacol. pmid:25746462
Exarchou V et al. HPLC-SPE-NMR characterization of major metabolites in Salvia fruticosa Mill. extract with antifungal potential: relevance of carnosic acid, carnosol, and hispidulin. 2015 J. Agric. Food Chem. pmid:25537192
Gao H et al. Hispidulin inhibits proliferation and enhances chemosensitivity of gallbladder cancer cells by targeting HIF-1α. 2015 Exp. Cell Res. pmid:25499970
Yang L et al. Comparative effects of hispidulin, genistein, and icariin with estrogen on bone tissue in ovariectomized rats. 2014 Cell Biochem. Biophys. pmid:24748177
Niu X et al. The effects of hispidulin on bupivacaine-induced neurotoxicity: role of AMPK signaling pathway. 2014 Cell Biochem. Biophys. pmid:24659139