Leukotriene b4

Leukotriene b4 is a lipid of Fatty Acyls (FA) class. The involved functions are known as Chemotaxis, release of sequestered calcium ion into cytoplasm and Polymerization. Leukotriene b4 often locates in Protoplasm. The associated genes with Leukotriene b4 are phallacidin.

Cross Reference

Introduction

To understand associated biological information of Leukotriene b4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Leukotriene b4?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Leukotriene b4

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Hypoxia D000860 23 associated lipids
Adenocarcinoma D000230 166 associated lipids
Enterocolitis D004760 3 associated lipids
Breast Neoplasms D001943 24 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Leukotriene b4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Leukotriene b4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Leukotriene b4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Leukotriene b4?

There are no associated biomedical information in the current reference collection.

What genes are associated with Leukotriene b4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Leukotriene b4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Leukotriene b4

Download all related citations
Per page 10 20 50 100 | Total 5221
Authors Title Published Journal PubMed Link
Bitto A et al. Effects of COX1-2/5-LOX blockade in Alzheimer transgenic 3xTg-AD mice. 2017 Inflamm. Res. pmid:28238167
Ying W et al. Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling. 2017 J. Clin. Invest. pmid:28192375
Archambault AS et al. Leukotriene B₄ Metabolism and p70S6 Kinase 1 Inhibitors: PF-4708671 but Not LY2584702 Inhibits CYP4F3A and the ω-Oxidation of Leukotriene B₄ In Vitro and In Cellulo. 2017 PLoS ONE pmid:28068410
Min A et al. SNAP23-Dependent Surface Translocation of Leukotriene B4 (LTB4) Receptor 1 Is Essential for NOX2-Mediated Exocytotic Degranulation in Human Mast Cells Induced by Trichomonas vaginalis-Secreted LTB4. 2017 Infect. Immun. pmid:27795355
Spilker ME et al. Leveraging model-based study designs and serial micro-sampling techniques to understand the oral pharmacokinetics of the potent LTB4 inhibitor, CP-105696, for mouse pharmacology studies. 2017 Xenobiotica pmid:27435693
Pruzanski W et al. Hydrolysis of lipoproteins by sPLA2's enhances mitogenesis and eicosanoid release from vascular smooth muscle cells: Diverse activity of sPLA2's IIA, V and X. 2016 Prostaglandins Other Lipid Mediat. pmid:26711221
Ee MT et al. Leukotriene B4 mediates macrophage influx and pulmonary hypertension in bleomycin-induced chronic neonatal lung injury. 2016 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:27317685
Maddipati KR et al. Lipidomic analysis of patients with microbial invasion of the amniotic cavity reveals up-regulation of leukotriene B4. 2016 FASEB J. pmid:27312808
Gall BJ et al. Reduction of GPSM3 expression akin to the arthritis-protective SNP rs204989 differentially affects migration in a neutrophil model. 2016 Genes Immun. pmid:27307211
Marvar PJ et al. Systemic leukotriene B4 receptor antagonism lowers arterial blood pressure and improves autonomic function in the spontaneously hypertensive rat. 2016 J. Physiol. (Lond.) pmid:27230966