LTC4

Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.

Cross Reference

Introduction

To understand associated biological information of LTC4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with LTC4?

LTC4 is suspected in Pneumonia, Asthma, Pulmonary Eosinophilia, Eosinophilia, Cardiovascular Diseases, Disintegration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with LTC4

PubChem Associated disorders and diseases

What pathways are associated with LTC4

Lipid pathways are not clear in current pathway databases. We organized associated pathways with LTC4 through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with LTC4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with LTC4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with LTC4?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with LTC4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with LTC4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with LTC4

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Authors Title Published Journal PubMed Link
Huwiler A and Pfeilschifter J A role for protein kinase C-alpha in zymosan-stimulated eicosanoid synthesis in mouse peritoneal macrophages. 1993 Eur. J. Biochem. pmid:8223588
Wallis RA and Panizzon KL Protection from hypoxic and N-methyl-D-aspartate injury with azelastine, a leukotriene inhibitor. 1993 Eur. J. Pharmacol. pmid:8405089
Katori M et al. Interaction of substance P and leukotriene C4 in ethanol-induced mucosal injury of rat stomach. 1993 Regul. Pept. pmid:7692504
Patella V et al. Protein Fv produced during vital hepatitis is a novel activator of human basophils and mast cells. 1993 J. Immunol. pmid:7693815
Böhme M et al. Differential inhibition by cyclosporins of primary-active ATP-dependent transporters in the hepatocyte canalicular membrane. 1993 FEBS Lett. pmid:8224162
Ebersole JL et al. Inflammatory mediators and immunoglobulins in GCF from healthy, gingivitis and periodontitis sites. 1993 J. Periodont. Res. pmid:8263728
Mita H et al. Purification of human blood basophils and leukotriene C4 generation following calcium ionophore stimulation. 1993 Prostaglandins Leukot. Essent. Fatty Acids pmid:7505057
Lee TH and Christie PE Leukotrienes and aspirin induced asthma. 1993 Thorax pmid:8303620
Kurosawa M et al. Inhibition of bronchial hyperresponsiveness to histamine induced by intravenous administration of leukotriene C4 by novel thromboxane A2 receptor antagonists ONO-NT-126 and ONO-8809 in guinea-pigs. 1993 Clin. Exp. Allergy pmid:10780891
Zuany-Amorim C et al. Characterization and pharmacological modulation of antigen-induced peritonitis in actively sensitized mice. 1993 Br. J. Pharmacol. pmid:7694762