3-O-Methylquercetin

3-O-Methylquercetin is a lipid of Polyketides (PK) class. 3-o-methylquercetin is associated with abnormalities such as Colitis, Hemorrhagic diarrhea and Diabetes. The involved functions are known as Inflammation, Trans-Activation (Genetics), Signal Transduction, Binding, Competitive and Antiinflammatory Effect. 3-o-methylquercetin often locates in Mucous Membrane. The associated genes with 3-O-Methylquercetin are IL2 gene, Human gene and ABCB1 gene. The related experimental models are Streptozotocin Diabetes.

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Introduction

To understand associated biological information of 3-O-Methylquercetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 3-O-Methylquercetin?

3-O-Methylquercetin is suspected in Colitis, Hemorrhagic diarrhea, Diabetes and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 3-O-Methylquercetin

MeSH term MeSH ID Detail
Cell Transformation, Neoplastic D002471 126 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with 3-O-Methylquercetin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 3-O-Methylquercetin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 3-O-Methylquercetin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 3-O-Methylquercetin?

There are no associated biomedical information in the current reference collection.

What genes are associated with 3-O-Methylquercetin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 3-O-Methylquercetin?

Streptozotocin Diabetes

Streptozotocin Diabetes are used in the study 'Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway.' (Dou W et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with 3-O-Methylquercetin

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Authors Title Published Journal PubMed Link
Hu S et al. Isorhamnetin inhibits cell proliferation and induces apoptosis in breast cancer via Akt and mitogen‑activated protein kinase kinase signaling pathways. 2015 Mol Med Rep pmid:26502751
Park YJ et al. Inhibitory Aromatase Effects of Flavonoids from Ginkgo Biloba Extracts on Estrogen Biosynthesis. 2015 Asian Pac. J. Cancer Prev. pmid:26434836
Messer JG et al. Quercetin Metabolites Up-Regulate the Antioxidant Response in Osteoblasts Isolated From Fetal Rat Calvaria. 2015 J. Cell. Biochem. pmid:25716194
Jimenez R et al. Quercetin and its metabolites inhibit the membrane NADPH oxidase activity in vascular smooth muscle cells from normotensive and spontaneously hypertensive rats. 2015 Food Funct pmid:25562607
Xie Y et al. Comparison of isorhamnetin absorption properties in total flavones of Hippophae rhamnoides L. with its pure form in a Caco-2 cell model mediated by multidrug resistance-associated protein. 2015 Eur J Pharm Sci pmid:25813735
Maciej J et al. Bioavailability of the flavonol quercetin in neonatal calves after oral administration of quercetin aglycone or rutin. 2015 J. Dairy Sci. pmid:25795488
Shaheen N et al. Separation of isorhamnetin 3-sulphate and astragalin from Flaveria bidentis (L.) Kuntze using macroporous resin and followed by high-speed countercurrent chromatography. 2015 J Sep Sci pmid:25763770
Wiczkowski W et al. Quercetin and isorhamnetin aglycones are the main metabolites of dietary quercetin in cerebrospinal fluid. 2015 Mol Nutr Food Res pmid:25727325
Rodríguez-Rodríguez C et al. The effect of isorhamnetin glycosides extracted from Opuntia ficus-indica in a mouse model of diet induced obesity. 2015 Food Funct pmid:25588195
Wang H et al. A phospholipid complex to improve the oral bioavailability of flavonoids. 2015 Drug Dev Ind Pharm pmid:25496311