Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Hypolipoproteinemias D007009 9 associated lipids
Bacteremia D016470 9 associated lipids
Salmonella Infections, Animal D012481 9 associated lipids
Hypertension, Renal D006977 9 associated lipids
Coronary Vasospasm D003329 9 associated lipids
Rhinitis D012220 10 associated lipids
Hypertension, Renovascular D006978 10 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Retinal Detachment D012163 10 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

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Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Bockman RS Prostaglandin production by human blood monocytes and mouse peritoneal macrophages: synthesis dependent on in vitro culture conditions. 1981 Prostaglandins pmid:6782622
Singh D et al. Evidence for the generation of hydroxyl radical during arachidonic acid metabolism by human platelets. 1981 Am. J. Hematol. pmid:6274189
Smith EF and Lefer AM Stabilization of cardiac lysosomal and cellular membranes in protection of ischemic myocardium due to coronary occlusion:efficacy of the nonsteroidal anti-inflammatory agent, naproxen. 1981 Am. Heart J. pmid:7211667
Shaw JO et al. Activation of rabbit platelet phospholipase and thromboxane synthesis by 1-O-hexadecyl/octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine (platelet activating factor). 1981 Biochim. Biophys. Acta pmid:7213765
Kass MA et al. Prostaglandin and thromboxane synthesis by microsomes of inflamed rabbit ciliary body--iris. 1981 Invest. Ophthalmol. Vis. Sci. pmid:7216665
Sakio H et al. [Release of thromboxane A2 during hemorrhagic shock (author's transl)]. 1981 Masui pmid:7218508
Kawaguchi H et al. Thromboxane B2 biosynthesis and phospholipids hydrolysis in platelets from hypercholesterolemic rabbits. 1981 Lipids pmid:7219079
Roy AC et al. Effect of intravenous infusion of OKY-1581 (sodium-(E)-3-[4-(3-pyridylmethyl)phenyl] -2-methylacrylate) on circulatory thromboxane A2 and prostacyclin levels in anaesthetized baboon. 1981 Prostaglandins Med pmid:7029585
Stuart MJ Effect of endotoxin on arachidonic acid release and thromboxane B2 production by human platelets. 1981 Am. J. Hematol. pmid:7030066
Dembélé-Duchesne MJ et al. Some new prospects in the mechanism of control of arachidonate metabolism in human placenta and amnion. 1981 Prostaglandins pmid:6801732
Lorenz R et al. Effects of very low versus standard dose acetyl salicylic acid, dipyridamole and sulfinpyrazone on platelet function and thromboxane formation in man. 1981 Eur. J. Pharmacol. pmid:7238575
Polley MJ et al. Human complement in the arachidonic acid transformation pathway in platelets. 1981 J. Exp. Med. pmid:7241047
Greenberg S et al. Pulmonary vascular smooth muscle function in porcine splanchnic arterial occlusion shock. 1981 Am. J. Physiol. pmid:7246787
Townsend ER et al. Preservation of platelets during extracorporeal circulation in sheep. A comparison between aspirin and sulfinpyrazone. 1981 Circ. Res. pmid:7249281
McCann DS et al. Radioimmunoassay for plasma thromboxane B2. 1981 Clin. Chem. pmid:7273401
Coker SJ et al. Aspirin inhibits the early myocardial release of thromboxane B2 and ventricular ectopic activity following acute coronary artery occlusion in dogs. 1981 Br. J. Pharmacol. pmid:7284679
Bishai I and Coceani F Transformations of prostaglandin H2 in the cat brain. 1981 Biochim. Biophys. Acta pmid:6894549
Drake TS et al. Peritoneal fluid thromboxane B2 and 6-keto-prostaglandin F1 alpha in endometriosis. 1981 Am. J. Obstet. Gynecol. pmid:6894667
Halushka PV et al. Protective effects of aspirin in endotoxic shock. 1981 J. Pharmacol. Exp. Ther. pmid:6894770
Feuerstein N et al. Leukotrienes C4 and D4 induce prostaglandin and thromboxane release from rat peritoneal macrophages. 1981 Br. J. Pharmacol. pmid:6894882
Karmazyn M et al. Comparative effects of acetylsalicylic acid (ASA) and sulfinpyrazone on isoproterenol-induced heart damage. 1981 J. Pharmacol. Exp. Ther. pmid:6894943
Morrison AR and Benabe JE Prostaglandins in vascular tone in experimental obstructive nephropathy. 1981 Kidney Int. pmid:6894950
Bombardieri S et al. The synovial prostaglandin system in chronic inflammatory arthritis: differential effects of steroidal and nonsteroidal anti-inflammatory drugs. 1981 Br. J. Pharmacol. pmid:6895043
Harms BA et al. Prostaglandin release and altered microvascular integrity after burn injury. 1981 J. Surg. Res. pmid:6895238
Ylikorkala O et al. Amniotic fluid prostacyclin and thromboxane in normal, preeclamptic, and some other complicated pregnancies. 1981 Am. J. Obstet. Gynecol. pmid:6895277
Defreyn G et al. Familial bleeding tendency with partial platelet thromboxane synthetase deficiency: reorientation of cyclic endoperoxide metabolism. 1981 Br. J. Haematol. pmid:6268139
Prancan A et al. Platelet thromboxane production during endotoxin shock. 1981 Agents Actions pmid:7340458
Hwang DH Characteristics of the aggregation of platelets and the formation of prostaglandins (PGs) in rat. 1981 Prog. Lipid Res. pmid:7342108
Agradi E et al. In vitro effects of synthetic antioxidants and vitamin E on arachidonic acid metabolism and thromboxane formation in human platelets and on platelet aggregation. 1981 Prostaglandins pmid:6794104
Halushka PV et al. Increased platelet thromboxane synthesis in diabetes mellitus. 1981 J. Lab. Clin. Med. pmid:7452084
Laviolette M et al. Human alveolar macrophages: a lesion in arachidonic acid metabolism in cigarette smokers. 1981 Am. Rev. Respir. Dis. pmid:6794395
Grimm LJ et al. Inhibition of platelet thromboxane synthesis by 7-(1-imidazolyl) heptanoic acid: dissociation from inhibition of aggregation. 1981 Thromb. Res. pmid:6801806
Worthington RE and Nakeff A Thromboxane synthesis in megakaryocytes isolated by centrifugal elutriation. 1981 Blood pmid:6786393
Igarashi K et al. Effect of polyamines on prostaglandin synthesis in various cell-free systems. 1981 Biochem. Biophys. Res. Commun. pmid:6800368
Landgraf-Leurs MM et al. Aggregation and thromboxane B2 formation in platelets and vascular prostacyclin production from genetically obese rats. 1981 Prostaglandins pmid:6798637
Tsuboi T et al. Effect of gliclazide on prostaglandin and thromboxane synthesis in guinea-pig platelets. 1981 Jan 1-15 Thromb. Res. pmid:7233394
Randall MJ et al. UK-37, 248, a novel, selective thromboxane synthetase inhibitor with platelet anti-aggregatory and anti-thrombotic activity. 1981 Jul 1-15 Thromb. Res. pmid:6795753
Kelton JG et al. Sex-related differences in the efficacy of acetylsalicylic acid (ASA) : the absorption of ASA and its effect on collagen-induced thromboxane B2 generation. 1981 Oct 1-15 Thromb. Res. pmid:7330835
Fitzpatrick FA A radioimmunoassay for thromboxane B2. 1982 Meth. Enzymol. pmid:7132759
Maas RL et al. Quantitative assay of urinary 2,3-dinor thromboxane B2 by GC-MS. 1982 Meth. Enzymol. pmid:7132771
Martin JF et al. Effect of acetylsalicylic acid on platelet aggregation and thromboxane B2 production in flowing aortic blood in the rat studied with a filter loop technique. 1982 Thromb. Res. pmid:6814004
Goldsmith JC and Needleman SW A comparative study of thromboxane and prostacyclin release from ex vivo and cultured bovine vascular endothelium. 1982 Prostaglandins pmid:6815717
Blackwell GJ et al. Prostacyclin prolongs viability of washed human platelets. 1982 Biochim. Biophys. Acta pmid:6291622
Karmali RA et al. Prostaglandin regulation of murine mammary tumor virus production: a basis for some of the glucocorticoid and prolactin actions on mammary tumor cell cultures. 1982 Prostaglandins Leukot Med pmid:6296884
Castaldi PA et al. Evidence for a platelet membrane defect in the myeloproliferative syndromes. 1982 Thromb. Res. pmid:6960545
Ody C et al. 6-Ketoprostaglandin F1 alpha, prostaglandins E2, F2 alpha and thromboxane B2 production by endothelial cells, smooth muscle cells and fibroblasts cultured from piglet aorta. 1982 Biochim. Biophys. Acta pmid:6214281
Casey LC et al. Prevention of endotoxin-induced pulmonary hypertension in primates by the use of a selective thromboxane synthetase inhibitor, OKY 1581. 1982 J. Pharmacol. Exp. Ther. pmid:6896528
Mehta J and Mehta P Effects of propranolol therapy on platelet release and prostaglandin generation in patients with coronary heart disease. 1982 Circulation pmid:6216027
Mehta P et al. Thromboxane and prostacyclin generation by intact human vessels in response to balloon catheter trauma. 1982 Prostaglandins Leukot Med pmid:6217465
Miller JL et al. Arachidonic acid metabolism in guinea pig megakaryocytes. 1982 Biochem. Biophys. Res. Commun. pmid:6812584