Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Wen SH et al. | Ischemic postconditioning during reperfusion attenuates intestinal injury and mucosal cell apoptosis by inhibiting JAK/STAT signaling activation. | 2012 | Shock | pmid:22777122 |
Vazzana N et al. | Endogenous secretory RAGE in obese women: association with platelet activation and oxidative stress. | 2012 | J. Clin. Endocrinol. Metab. | pmid:22761461 |
Wenzel F et al. | Determination of thromboxane formation, soluble CD40L release and thrombopoietin clearance in apheresis platelet concentrates. | 2012 | Platelets | pmid:21806498 |
Zhou CB et al. | Decrease in inflammatory response does not prevent placental dysfunction after fetal cardiac bypass in goats. | 2012 | J. Thorac. Cardiovasc. Surg. | pmid:21821267 |
Cesari M et al. | Oxidative damage, platelet activation, and inflammation to predict mobility disability and mortality in older persons: results from the health aging and body composition study. | 2012 | J. Gerontol. A Biol. Sci. Med. Sci. | pmid:22389462 |
Dragani A et al. | Oxidative stress and platelet activation in subjects with moderate hyperhomocysteinaemia due to MTHFR 677 C→T polymorphism. | 2012 | Thromb. Haemost. | pmid:22782530 |
Saito Y et al. | Disruption of group IVA cytosolic phospholipase A(2) attenuates myocardial ischemia-reperfusion injury partly through inhibition of TNF-α-mediated pathway. | 2012 | Am. J. Physiol. Heart Circ. Physiol. | pmid:22427514 |
Barberà -Cremades M et al. | P2X7 receptor-stimulation causes fever via PGE2 and IL-1β release. | 2012 | FASEB J. | pmid:22490780 |
Su CL et al. | Inducible cyclooxygenase expression mediating hypoxia/reoxygenation-induced pulmonary vasoconstriction is attenuated by a cyclooxygenase inhibitor in rats. | 2012 | Transplant. Proc. | pmid:22564588 |
Ames PR et al. | Aspirin insensitive thromboxane generation is associated with oxidative stress in type 2 diabetes mellitus. | 2012 | Thromb. Res. | pmid:22521214 |
Skarke C et al. | Comparative impact on prostanoid biosynthesis of celecoxib and the novel nonsteroidal anti-inflammatory drug CG100649. | 2012 | Clin. Pharmacol. Ther. | pmid:22278334 |
Ledwidge MT et al. | In vivo impact of prodrug isosorbide-5-nicotinate-2-aspirinate on lipids and prostaglandin D2: is this a new immediate-release therapeutic option for niacin? | 2012 | Atherosclerosis | pmid:22326030 |
Chen C et al. | [Effects of extracts of Radix Scrophulariae on blood pressure in spontaneously hypertensive rats and the underlying mechanisms]. | 2012 | Zhong Xi Yi Jie He Xue Bao | pmid:22979933 |
Etulain J et al. | Acidosis downregulates platelet haemostatic functions and promotes neutrophil proinflammatory responses mediated by platelets. | 2012 | Thromb. Haemost. | pmid:22159527 |
Mayer AM et al. | Marine sponge Hymeniacidon sp. amphilectane metabolites potently inhibit rat brain microglia thromboxane B2 generation. | 2012 | Bioorg. Med. Chem. | pmid:22153874 |
Yang D et al. | Effects of short- and long-term hypercholesterolemia on contrast-induced acute kidney injury. | 2012 | Am. J. Nephrol. | pmid:22189165 |
Mustonen K et al. | Dose-response investigation of oral ketoprofen in pigs challenged with Escherichia coli endotoxin. | 2012 | Vet. Rec. | pmid:22735989 |
Zhao Y et al. | [Effects of the effective components group of xiaoshuantongluo formula on rat acute blood stasis model]. | 2012 | Yao Xue Xue Bao | pmid:22812003 |
Ju HK et al. | Metabolomic investigation of the anti-platelet aggregation activity of ginsenoside Rkâ‚ reveals attenuated 12-HETE production. | 2012 | J. Proteome Res. | pmid:22873173 |
Matsuura E et al. | On aspirin treatment but not baseline thromboxane B2 levels predict adverse outcomes in patients with acute coronary syndromes. | 2012 | J. Thromb. Haemost. | pmid:22784188 |