Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Gastritis D005756 27 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Glioma D005910 112 associated lipids
Glomerulonephritis D005921 35 associated lipids
Glomerulonephritis, IGA D005922 7 associated lipids
Glomerulosclerosis, Focal Segmental D005923 4 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Rhinitis, Allergic, Seasonal D006255 7 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Heart Failure D006333 36 associated lipids
Heart Septal Defects D006343 2 associated lipids
Heart Valve Diseases D006349 4 associated lipids
Hemolysis D006461 131 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Hemorrhagic Fever with Renal Syndrome D006480 3 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hydatidiform Mole D006828 3 associated lipids
Hyperaldosteronism D006929 4 associated lipids
Hyperalgesia D006930 42 associated lipids
Hypercapnia D006935 5 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Hyperemia D006940 25 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Hyperlipoproteinemia Type IV D006953 6 associated lipids
Hypersensitivity D006967 22 associated lipids
Hypertension D006973 115 associated lipids
Hypertension, Portal D006975 12 associated lipids
Hypertension, Pulmonary D006976 32 associated lipids
Hypertension, Renal D006977 9 associated lipids
Hypertension, Renovascular D006978 10 associated lipids
Hypolipoproteinemias D007009 9 associated lipids
Hypotension D007022 41 associated lipids
Hypothyroidism D007037 32 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Infertility D007246 3 associated lipids
Inflammation D007249 119 associated lipids
Influenza, Human D007251 11 associated lipids
Intermittent Claudication D007383 6 associated lipids
Jejunal Diseases D007579 3 associated lipids
Keratitis D007634 7 associated lipids
Kidney Diseases D007674 29 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Leiomyosarcoma D007890 4 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Leukopenia D007970 9 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Liver Cirrhosis, Biliary D008105 12 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Liver Diseases, Alcoholic D008108 13 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lupus Nephritis D008181 8 associated lipids
Macular Edema D008269 3 associated lipids
Magnesium Deficiency D008275 9 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Mastitis, Bovine D008414 8 associated lipids
Mastocytosis D008415 5 associated lipids
Meningioma D008579 11 associated lipids
Menorrhagia D008595 4 associated lipids
Migraine Disorders D008881 11 associated lipids
Mixed Connective Tissue Disease D008947 2 associated lipids
Mucocutaneous Lymph Node Syndrome D009080 9 associated lipids
Myocardial Infarction D009203 21 associated lipids
Nasal Polyps D009298 26 associated lipids
Nephritis D009393 19 associated lipids
Nephrotic Syndrome D009404 11 associated lipids
Neutropenia D009503 15 associated lipids
Obesity, Morbid D009767 8 associated lipids
Oligomenorrhea D009839 1 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Pain D010146 64 associated lipids
Pain, Postoperative D010149 13 associated lipids
Peptic Ulcer D010437 19 associated lipids
Periapical Periodontitis D010485 6 associated lipids
Placenta Diseases D010922 5 associated lipids
Platelet Storage Pool Deficiency D010981 3 associated lipids
Pleurisy D010998 20 associated lipids
Pneumonia D011014 10 associated lipids
Pneumonia, Aspiration D011015 3 associated lipids
Pneumonia, Viral D011024 3 associated lipids
Polycythemia Vera D011087 13 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Pregnancy Complications D011248 19 associated lipids
Pregnancy Complications, Cardiovascular D011249 11 associated lipids
Pregnancy Complications, Hematologic D011250 11 associated lipids
Proteinuria D011507 30 associated lipids
Pulmonary Edema D011654 23 associated lipids
Pulmonary Embolism D011655 5 associated lipids
Pulmonary Heart Disease D011660 2 associated lipids
Purpura, Schoenlein-Henoch D011695 5 associated lipids
Purpura, Thrombotic Thrombocytopenic D011697 6 associated lipids
Radiation Injuries, Experimental D011833 11 associated lipids
Radiculopathy D011843 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Svensson J and Samuelsson K Inhibition of platelet function by low dose acetylsalicylic acid in patients with cerebrovascular disease. 1983 Thromb. Res. pmid:20218005
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Thorngren M et al. Thromboxane A2 in skin-bleeding-time blood and in clotted venous blood before and after administration of acetylsalicylic acid. 1983 Lancet pmid:6133107
Drake TS et al. Peritoneal fluid prostanoids in unexplained infertility. 1983 Am. J. Obstet. Gynecol. pmid:6614085
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Menys VC and Davies JA Inhibitory effects of ZK 36374, a stable prostacyclin analogue, on adhesion of rabbit platelets to damaged aorta and serotonin release by adherent platelets. 1983 Clin. Sci. pmid:6190604
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Ditter H et al. Effects of prostacyclin during cardiopulmonary bypass in men on plasma levels of beta-thromboglobulin, platelet factor 4, thromboxane B2, 6-keto-prostaglandin F1 alpha and heparin. 1983 Thromb. Res. pmid:6197766
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Lismonde M et al. [The presence of 6-oxo-PGF1alpha and thromboxane B2 in peritoneal exudates released by iota-carrageenan in the rat]. 1983 Arch. Int. Physiol. Biochim. pmid:6198994
Gorman RR et al. Inhibition of platelet thromboxane A2 synthase activity by sodium 5-(3'-pyridinylmethyl)benzofuran-2-carboxylate. 1983 Prostaglandins pmid:6316421
Tolman EL and Fuller BL Inhibition of thromboxane synthesis in guinea pig lung and human platelets by clotrimazole and other imidazole antifungals. 1983 Biochem. Pharmacol. pmid:6316985
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Salmon JA et al. The effects of BW755C and other anti-inflammatory drugs on eicosanoid concentrations and leukocyte accumulation in experimentally-induced acute inflammation. 1983 J. Pharm. Pharmacol. pmid:6141244
Stimler NP and O'Flaherty JT Spasmogenic properties of platelet-activating factor: evidence for a direct mechanism in the contractile response of pulmonary tissues. 1983 Am. J. Pathol. pmid:6624879
Nerlich M et al. Effect of thermal injury on endotoxin-induced lung injury. 1983 Surgery pmid:6337423
Harlan J et al. Selective inhibition of thromboxane synthesis during experimental endotoxemia in the goat: effects on pulmonary haemodynamics and lung lymph flow. 1983 Br J Clin Pharmacol pmid:6337602
Ball HA et al. Effect of dazoxiben, a specific inhibitor of thromboxane synthetase, on acute pulmonary responses to E. coli endotoxin in anaesthetized cats. 1983 Br J Clin Pharmacol pmid:6337603
McDaniel HG et al. Platelet function abnormalities in response to arachidonic acid in the acute phase of myocardial infarction. 1983 Am. J. Cardiol. pmid:6416046
Dodd NJ et al. Use of a thromboxane synthetase inhibitor, dazoxiben, during haemodialysis. 1983 Br J Clin Pharmacol pmid:6337605
Ylikorkala O et al. Maternal prostacyclin, thromboxane, and placental blood flow. 1983 Am. J. Obstet. Gynecol. pmid:6338724
Williams GA et al. Prostacyclin and thromboxane A2 derivatives in rhegmatogenous subretinal fluid. 1983 Arch. Ophthalmol. pmid:6338873
Ylikorkala O et al. Effect of vacuum curettage on the concentrations of plasma 6-keto-prostaglandin F1 alpha and serum thromboxane B2. 1983 Br J Obstet Gynaecol pmid:6338904
Marcella JJ et al. Exercise-induced myocardial ischemia in patients with coronary artery disease: lack of evidence for platelet activation or fibrin formation in peripheral venous blood. 1983 J. Am. Coll. Cardiol. pmid:6339591
Brox JH et al. Effects of cod liver oil on platelets and coagulation in familial hypercholesterolemia (type IIa). 1983 Acta Med Scand pmid:6340424
Mest HJ et al. The influence of linseed oil diet on fatty acid pattern in phospholipids and thromboxane formation in platelets in man. 1983 Klin. Wochenschr. pmid:6341702
Hartung HP et al. Stimulation of prostaglandin E and thromboxane synthesis in macrophages by purified C3b. 1983 J. Immunol. pmid:6343486
Boughton-Smith NK et al. Biosynthesis of lipoxygenase and cyclo-oxygenase products from [14C]-arachidonic acid by human colonic mucosa. 1983 Gut pmid:6416934
Deckmyn H et al. Prostacyclin production by whole blood from children: impairment in the hemolytic uremic syndrome and excessive formation in chronic renal failure. 1983 Thromb. Res. pmid:6344317
Bromberg Y and Pick E Unsaturated fatty acids as second messengers of superoxide generation by macrophages. 1983 Cell. Immunol. pmid:6307532
Ylikorkala O and Viinikka L Prostaglandins and endometriosis. 1983 Acta Obstet Gynecol Scand Suppl pmid:6344540
Vlasses PH et al. Urinary excretion of prostacyclin and thromboxane A2 metabolites after angiotensin converting enzyme inhibition in hypertensive patients. 1983 Prostaglandins Leukot Med pmid:6308685
Huval WV et al. Thromboxane mediation of cardiovascular dysfunction following aspiration. 1983 Surgery pmid:6308843
Hartung HP Acetyl glyceryl ether phosphorylcholine (platelet-activating factor) mediates heightened metabolic activity in macrophages. Studies on PGE, TXB2 and O2- production, spreading, and the influence of calmodulin-inhibitor W-7. 1983 FEBS Lett. pmid:6309563
Chetty N and Bradlow BA The effects of a vegetarian diet on platelet function and fatty acids. 1983 Thromb. Res. pmid:6612688
Buchanan MR et al. The sex-related differences in aspirin pharmacokinetics in rabbits and man and its relationship to antiplatelet effects. 1983 Thromb. Res. pmid:6221436
Yamamoto S et al. Enzyme immunoassay of thromboxane B2 and 6-keto-prostaglandin F1 alpha as a substitute for radioimmunoassay. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221523
Ujiie A et al. [Studies on the inhibitory effect of etafenone hydrochloride on platelet aggregation]. 1983 Nippon Yakurigaku Zasshi pmid:6618341
Weerasekera DA et al. Chemiluminescence immunoassay of thromboxane B2. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221524
Kawaguchi H Thromboxane synthesis in hypercholesterolemic platelets--on the mechanism of increased thromboxane synthesis. 1983 Hokkaido Igaku Zasshi pmid:6618425
Ito T et al. Effects of a selective inhibitor of thromboxane synthetase (OKY-1581) in humans. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221531
Dubin NH et al. Thromboxane production in the pregnant rat: differential recovery by platelets and uterus following aspirin administration. 1983 Biol. Reprod. pmid:6626652
Nuotto E et al. Effect of acetylsalicylic acid on plasma thromboxane B2 and platelet aggregation in man. 1983 Eur. J. Clin. Pharmacol. pmid:6628518
Feddersen CO et al. Leukotriene E4 causes pulmonary vasoconstriction, not inhibited by meclofenamate. 1983 Prostaglandins pmid:6098932
Mandrovnaia NV et al. [Age-related changes in prostacyclin and thromboxane B2 biosynthesis under normal conditions and in arterial hypertension]. 1983 Kardiologiia pmid:6366325
Sinzinger H and Firbas W [Cells of the vascular wall synthesize thromboxane]. 1983 Wien. Klin. Wochenschr. pmid:6369802
Schumacher WA and Lucchesi BR Effect of the thromboxane synthetase inhibitor UK-37,248 (dazoxiben) upon platelet aggregation, coronary artery thrombosis and vascular reactivity. 1983 J. Pharmacol. Exp. Ther. pmid:6418881
Morita I et al. Stimulation of eicosapentaenoic acid metabolism in washed human platelets by 12-hydroperoxyeicosatetraenoic acid. 1983 J. Biol. Chem. pmid:6309794
Mehta P et al. Inhibitory effects of diltiazem on platelet activation caused by ionophore A23187 plus ADP or epinephrine in subthreshold concentrations. 1983 J. Lab. Clin. Med. pmid:6411841
Westwick J et al. Platelet activation during steady state sickle cell disease. 1983 J Med pmid:6224876
Ellsworth ML et al. Pulmonary prostacyclin production with increased flow and sympathetic stimulation. 1983 J Appl Physiol Respir Environ Exerc Physiol pmid:6415017
Dahl ML et al. Sodium salicylate interferes with the inhibitory effects of aspirin and indomethacin on human platelets. 1983 Prostaglandins Leukot Med pmid:6415666
Halushka PV et al. Studies on the beneficial effects of aspirin in endotoxic shock. Relationship to inhibition of arachidonic acid metabolism. 1983 Am. J. Med. pmid:6687979
Tsukatani E Etiology of EPH-gestosis from the viewpoint of dynamics of vasoactive prostanoid, lipid peroxides and vitamin E. 1983 Nippon Sanka Fujinka Gakkai Zasshi pmid:6688085
Han P et al. Verapamil and collagen-induced platelet reactions--evidence for a role for intracellular calcium in platelet activation. 1983 Thromb. Haemost. pmid:6415847
Fischer S et al. In vivo and in vitro effects of nafazatrom (Bay g 6575), an antithrombotic compound, on arachidonic acid metabolism in platelets and vascular tissue. 1983 Biochem. Pharmacol. pmid:6688182
Barnhart MI et al. DDAVP: does the drug have a direct effect on the vessel wall? 1983 Thromb. Res. pmid:6415852
Bailey IA et al. Effects of vascular trauma and transient myocardial ischaemia on coronary venous prostaglandin levels in the dog. 1983 Cardiovasc. Res. pmid:6688202
Wallis RB Mechanisms of action of sulphinpyrazone. 1983 Thromb. Res. Suppl. pmid:6415857
Srivastava KC and Awasthi KK Separation and quantitative determination of radiolabeled prostaglandins, thromboxanes, 6-keto-prostaglandin F1 alpha and other arachidonic acid metabolites produced in biological material. 1983 J. Chromatogr. pmid:6688256
Wilson L and Huang LS Effects of the fetal-placental unit on uterine prostaglandin levels at term in the pregnant rat. 1983 Prostaglandins pmid:6688474
Saldeen P and Saldeen T 6-keto-prostaglandin F1 alpha/thromboxane B2 ratio in vascular and lung tissue. 1983 Thromb. Res. pmid:6688484
Wilson TW Responses to furosemide in normotensive and hypertensive subjects. 1983 Clin. Pharmacol. Ther. pmid:6688772
Gurtner GH et al. Oxidant- and lipid-induced pulmonary vasoconstriction mediated by arachidonic acid metabolites. 1983 J Appl Physiol Respir Environ Exerc Physiol pmid:6688802
van Rijk GL et al. Long-term myocardial preservation: thromboxane production and coronary resistance. 1983 J. Surg. Res. pmid:6688844
Miller JB et al. Alterations in plasma and tissue prostaglandin levels in rabbits during luteal regression. 1983 Biol. Reprod. pmid:6688954
Davì G et al. The effect of two low doses of aspirin on whole blood thromboxane and prostacyclin generation in healthy subjects. 1983 Thromb. Haemost. pmid:6417815
Muccitelli RM et al. Effect of inhibition of thromboxane production on the leukotriene D4-mediated bronchoconstriction in the guinea pig. 1983 Prostaglandins pmid:6689082
Dale J et al. The effect of a thromboxane synthetase inhibitor, dazoxiben, and acetylsalicylic acid on platelet function and prostaglandin metabolism. 1983 Thromb. Haemost. pmid:6689091
Liu J [Effect of Paeonia obovata 801 on metabolism of thromboxane B2 and arachidonic acid and on platelet aggregation in patients with coronary heart disease and cerebral thrombosis]. 1983 Zhonghua Yi Xue Za Zhi pmid:6418338
Aehringhaus U et al. Effect of inhibition of synthesis and receptor antagonism of SRS-A in cardiac anaphylaxis. 1983 Br. J. Pharmacol. pmid:6689134
McDonald JW and Ali M Recovery of cyclooxygenase activity after aspirin in populations of platelets separated on stractan density gradients. 1983 Prostaglandins Leukot Med pmid:6419234
Moonen P et al. An improved method for separation of thromboxane B2 by reversed phase liquid chromatography. 1983 Prostaglandins pmid:6669711
Chong KP et al. Vasopressin stimulates thromboxane synthesis in isolated hamster hepatocytes: relation to hepatocyte calcium content. 1983 Prostaglandins pmid:6419286
Karmali RA et al. Prostaglandins in breast cancer: relationship to disease stage and hormone status. 1983 Br. J. Cancer pmid:6416285
Hartung HP et al. Induction of thromboxane release from macrophages by anaphylatoxic peptide C3a of complement and synthetic hexapeptide C3a 72-77. 1983 J. Immunol. pmid:6600482
Sautebin L et al. Preferential utilization of endogenous arachidonate by cyclo-oxygenase in incubations of human platelets. 1983 FEBS Lett. pmid:6407867
Zipser RD et al. Urinary thromboxane B2 and prostaglandin E2 in the hepatorenal syndrome: evidence for increased vasoconstrictor and decreased vasodilator factors. 1983 Gastroenterology pmid:6572162
Hoult JR and Robinson C Selective inhibition of thromboxane B2 accumulation and metabolism in perfused guinea-pig lung. 1983 Br. J. Pharmacol. pmid:6824820
Hirsh PD et al. Effects of provocation on transcardiac thromboxane in patients with coronary artery disease. 1983 Am. J. Cardiol. pmid:6829431
Walinsky P et al. Beneficial effects of ibuprofen in pacing-induced myocardial ischemia. 1983 Am. J. Cardiol. pmid:6829434
Reuben SR et al. Effects of dazoxiben on exercise performance in chronic stable angina. 1983 Br J Clin Pharmacol pmid:6402000
Rojas J et al. Effects of cyclooxygenase inhibition on the response to group B streptococcal toxin in sheep. 1983 Pediatr. Res. pmid:6402752
Förster W and Pönicke K Influence of sympathomimetic drugs (1-phenyl-2-amino-ethan-1-ol derivatives) on the biosynthesis of prostaglandins and thromboxane B2. 1983 Br. J. Pharmacol. pmid:6403094
Nenci GG et al. Platelet malondialdehyde production kinetics after cyclooxygenase block. A study performed with a modified high sensitivity assay. 1983 Haemostasis pmid:6404715
Lewy RI Role of thromboxanes in vasotonic versus vaso-occlusive angina. 1983 Arch Mal Coeur Vaiss pmid:6407435
Hayashi Y et al. Enzyme immunoassay of thromboxane B2. 1983 Biochim. Biophys. Acta pmid:6407530
Poyser NL and Brydon LJ Prostaglandin release from the guinea-pig uterus superfused in vitro. Effect of stage of estrous cycle, progesterone, estradiol, oxytocin and A23187. 1983 Prostaglandins pmid:6408712
Laitinen O et al. Plasma levels and urinary excretion of prostaglandins in patients with rheumatoid arthritis. 1983 Clin. Rheumatol. pmid:6589104
Ouwendijk RJ et al. Raised plasma levels of thromboxane B2 in systemic mastocytosis. 1983 Eur. J. Clin. Invest. pmid:6409646
Snapper JR et al. Effects of cyclooxygenase inhibitors on the alterations in lung mechanics caused by endotoxemia in the unanesthetized sheep. 1983 J. Clin. Invest. pmid:6409930
Carr BR et al. Prostaglandin secretion by the neocortex and fetal zones of the human fetal adrenal gland. 1983 J. Clin. Endocrinol. Metab. pmid:6313732