Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Gastritis D005756 27 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Glioma D005910 112 associated lipids
Glomerulonephritis D005921 35 associated lipids
Glomerulonephritis, IGA D005922 7 associated lipids
Glomerulosclerosis, Focal Segmental D005923 4 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Rhinitis, Allergic, Seasonal D006255 7 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Heart Failure D006333 36 associated lipids
Heart Septal Defects D006343 2 associated lipids
Heart Valve Diseases D006349 4 associated lipids
Hemolysis D006461 131 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Hemorrhagic Fever with Renal Syndrome D006480 3 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hydatidiform Mole D006828 3 associated lipids
Hyperaldosteronism D006929 4 associated lipids
Hyperalgesia D006930 42 associated lipids
Hypercapnia D006935 5 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Hyperemia D006940 25 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Hyperlipoproteinemia Type IV D006953 6 associated lipids
Hypersensitivity D006967 22 associated lipids
Hypertension D006973 115 associated lipids
Hypertension, Portal D006975 12 associated lipids
Hypertension, Pulmonary D006976 32 associated lipids
Hypertension, Renal D006977 9 associated lipids
Hypertension, Renovascular D006978 10 associated lipids
Hypolipoproteinemias D007009 9 associated lipids
Hypotension D007022 41 associated lipids
Hypothyroidism D007037 32 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Infertility D007246 3 associated lipids
Inflammation D007249 119 associated lipids
Influenza, Human D007251 11 associated lipids
Intermittent Claudication D007383 6 associated lipids
Jejunal Diseases D007579 3 associated lipids
Keratitis D007634 7 associated lipids
Kidney Diseases D007674 29 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Leiomyosarcoma D007890 4 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Leukopenia D007970 9 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Liver Cirrhosis, Biliary D008105 12 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Liver Diseases, Alcoholic D008108 13 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lupus Nephritis D008181 8 associated lipids
Macular Edema D008269 3 associated lipids
Magnesium Deficiency D008275 9 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Mastitis, Bovine D008414 8 associated lipids
Mastocytosis D008415 5 associated lipids
Meningioma D008579 11 associated lipids
Menorrhagia D008595 4 associated lipids
Migraine Disorders D008881 11 associated lipids
Mixed Connective Tissue Disease D008947 2 associated lipids
Mucocutaneous Lymph Node Syndrome D009080 9 associated lipids
Myocardial Infarction D009203 21 associated lipids
Nasal Polyps D009298 26 associated lipids
Nephritis D009393 19 associated lipids
Nephrotic Syndrome D009404 11 associated lipids
Neutropenia D009503 15 associated lipids
Obesity, Morbid D009767 8 associated lipids
Oligomenorrhea D009839 1 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Pain D010146 64 associated lipids
Pain, Postoperative D010149 13 associated lipids
Peptic Ulcer D010437 19 associated lipids
Periapical Periodontitis D010485 6 associated lipids
Placenta Diseases D010922 5 associated lipids
Platelet Storage Pool Deficiency D010981 3 associated lipids
Pleurisy D010998 20 associated lipids
Pneumonia D011014 10 associated lipids
Pneumonia, Aspiration D011015 3 associated lipids
Pneumonia, Viral D011024 3 associated lipids
Polycythemia Vera D011087 13 associated lipids
Adenomatous Polyposis Coli D011125 16 associated lipids
Pregnancy Complications D011248 19 associated lipids
Pregnancy Complications, Cardiovascular D011249 11 associated lipids
Pregnancy Complications, Hematologic D011250 11 associated lipids
Proteinuria D011507 30 associated lipids
Pulmonary Edema D011654 23 associated lipids
Pulmonary Embolism D011655 5 associated lipids
Pulmonary Heart Disease D011660 2 associated lipids
Purpura, Schoenlein-Henoch D011695 5 associated lipids
Purpura, Thrombotic Thrombocytopenic D011697 6 associated lipids
Radiation Injuries, Experimental D011833 11 associated lipids
Radiculopathy D011843 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Canales A et al. The effect of consuming meat enriched in walnut paste on platelet aggregation and thrombogenesis varies in volunteers with different apolipoprotein A4 genotype. 2010 Sep-Oct Nutr Hosp pmid:21336431
Fuchs I et al. Platelet hyperfunction is decreased by additional aspirin loading in patients presenting with myocardial infarction on daily aspirin therapy. 2010 Crit. Care Med. pmid:20400900
Steib CJ et al. Intraperitoneal LPS amplifies portal hypertension in rat liver fibrosis. 2010 Lab. Invest. pmid:20212458
Dragani A et al. The contribution of cyclooxygenase-1 and -2 to persistent thromboxane biosynthesis in aspirin-treated essential thrombocythemia: implications for antiplatelet therapy. 2010 Blood pmid:19887674
Kienzler JL et al. Systemic bioavailability of topical diclofenac sodium gel 1% versus oral diclofenac sodium in healthy volunteers. 2010 J Clin Pharmacol pmid:19841157
Würtz M et al. The antiplatelet effect of aspirin is reduced by proton pump inhibitors in patients with coronary artery disease. 2010 Heart pmid:19910291
Koeberle A et al. The molecular pharmacology and in vivo activity of 2-(4-chloro-6-(2,3-dimethylphenylamino)pyrimidin-2-ylthio)octanoic acid (YS121), a dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase. 2010 J. Pharmacol. Exp. Ther. pmid:19934399
Armstrong PC et al. Reduction of platelet thromboxane A2 production ex vivo and in vivo by clopidogrel therapy. 2010 J. Thromb. Haemost. pmid:19995405
Nørregaard R et al. Urinary tract obstruction induces transient accumulation of COX-2-derived prostanoids in kidney tissue. 2010 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:20147610
Carroll RC et al. Post interventional cardiology urinary thromboxane correlates with PlateletMapping detected aspirin resistance. 2010 Thromb. Res. pmid:19962724
Dragani A et al. Clinical and laboratory phenotype associated with the aspirin-like defect. 2010 Br. J. Haematol. pmid:19814736
Maddens BE et al. Validation of immunoassays for the candidate renal markers C-reactive protein, immunoglobulin G, thromboxane B2 and retinol binding protein in canine urine. 2010 Vet. Immunol. Immunopathol. pmid:19815297
Alusik S et al. The inhibitory effect of statins on urinary 11-dehydrothromboxane levels. 2010 Int Angiol pmid:20502413
Mangalpally KK et al. Platelet activation patterns in platelet size sub-populations: differential responses to aspirin in vitro. 2010 J. Thromb. Thrombolysis pmid:20502945
Cholette JM et al. Aspirin resistance following pediatric cardiac surgery. 2010 Thromb. Res. pmid:20550971
Youssef DT et al. New anti-inflammatory sterols from the Red Sea sponges Scalarispongia aqabaensis and Callyspongia siphonella. 2010 Nat Prod Commun pmid:20184014
Kidson-Gerber G et al. Serum thromboxane B2 compared to five other platelet function tests for the evaluation of aspirin effect in stable cardiovascular disease. 2010 Heart Lung Circ pmid:20144559
Montine TJ et al. Elevated ratio of urinary metabolites of thromboxane and prostacyclin is associated with adverse cardiovascular events in ADAPT. 2010 PLoS ONE pmid:20174466
King JN et al. In vitro and ex vivo inhibition of canine cyclooxygenase isoforms by robenacoxib: a comparative study. 2010 Res. Vet. Sci. pmid:20004922
Zisman E et al. Platelet function recovery after cessation of aspirin: preliminary study of volunteers and surgical patients. 2010 Eur J Anaesthesiol pmid:20035230
Butler BD et al. Circadian study of decompression sickness symptoms and response-associated variables in rats. 2010 Chronobiol. Int. pmid:20205563
Oldenhof J et al. Effect of maximum OTC doses of naproxen sodium or acetaminophen on low-dose aspirin inhibition of serum thromboxane B2. 2010 Curr Med Res Opin pmid:20429831
Boizel R et al. Regulation of oxidative stress and inflammation by glycaemic control: evidence for reversible activation of the 5-lipoxygenase pathway in type 1, but not in type 2 diabetes. 2010 Diabetologia pmid:20535444
Liu H et al. Aspirin inhibits fractalkine expression in atherosclerotic plaques and reduces atherosclerosis in ApoE gene knockout mice. 2010 Cardiovasc Drugs Ther pmid:19997773
Cavalca V et al. Simultaneous quantification of 8-iso-prostaglandin-F(2alpha) and 11-dehydro thromboxane B(2) in human urine by liquid chromatography-tandem mass spectrometry. 2010 Anal. Biochem. pmid:19825360
Dharmasaroja PA and Sae-Lim S Effects of different doses, enteric-coated preparation of aspirin, and sex on urinary 11-dehydrothromboxane B2 in healthy volunteers. 2010 Blood Coagul. Fibrinolysis pmid:20689403
Milara J et al. Cigarette smoke exposure up-regulates endothelin receptor B in human pulmonary artery endothelial cells: molecular and functional consequences. 2010 Br. J. Pharmacol. pmid:20698855
Anauate MC et al. Effect of isolated fractions of Harpagophytum procumbens D.C. (devil's claw) on COX-1, COX-2 activity and nitric oxide production on whole-blood assay. 2010 Phytother Res pmid:20812280
Yassine HN et al. Clinical determinants of aspirin resistance in diabetes. 2010 Diabetes Res. Clin. Pract. pmid:20719400
Würtz M et al. Patients with previous definite stent thrombosis have a reduced antiplatelet effect of aspirin and a larger fraction of immature platelets. 2010 JACC Cardiovasc Interv pmid:20723855
Kim SY et al. Platelet anti-aggregation activities of compounds from Cinnamomum cassia. 2010 J Med Food pmid:20828311
Bao YM et al. [Effect of precondition with GBE50 and Salviae miltionrrhizae on cycloxygenase-2 and its downstream effectors contents in ischemia/reperfusion myocardium]. 2010 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:21066890
De la Cruz JP et al. Differences in the in vitro antiplatelet effect of dexibuprofen, ibuprofen, and flurbiprofen in human blood. 2010 Anesth. Analg. pmid:21048099
Qu C et al. Chronic inhibition of nitric-oxide synthase potentiates endothelium-dependent contractions in the rat aorta by augmenting the expression of cyclooxygenase-2. 2010 J. Pharmacol. Exp. Ther. pmid:20444882
Renda G et al. Inconsistency of different methods for assessing ex vivo platelet function: relevance for the detection of aspirin resistance. 2010 Haematologica pmid:21123440
Iagoda AV and Gladkikh NN [Thromboxane-prostacyclin balance and platelet aggregability in patients with minor cardiac abnormalities]. 2010 Ter. Arkh. pmid:21086621
Warner JH et al. Adaptive regression modeling of biomarkers of potential harm in a population of U.S. adult cigarette smokers and nonsmokers. 2010 BMC Med Res Methodol pmid:20233412
Bollinger JG et al. Improved sensitivity mass spectrometric detection of eicosanoids by charge reversal derivatization. 2010 Anal. Chem. pmid:20704368
Fukushima H et al. Mechanisms underlying early development of pulmonary vascular obstructive disease in Down syndrome: An imbalance in biosynthesis of thromboxane A2 and prostacyclin. 2010 Am. J. Med. Genet. A pmid:20583254
Sato R et al. Inhibition of secretory phospholipase A2 activity attenuates lipopolysaccharide-induced acute lung injury in a mouse model. 2010 Exp. Lung Res. pmid:20426527
Ren R et al. Protective effects of Danshensu on liver injury induced by omethoate in rats. 2010 Toxicol. Mech. Methods pmid:20843270
Watanabe H et al. [Thromboxane A2 (TXA2), thromboxane B2(TXB2)]. 2010 Nippon Rinsho pmid:20963856
Wang BZ et al. [Association of the Pro1770Leu polymorphism in CYP5A1 gene with myocardial infarction in Uigur population of Xinjiang]. 2010 Zhonghua Yi Xue Yi Chuan Xue Za Zhi pmid:20931532
Wang BZ et al. [Association of Rs10487667 genetic polymorphism of thromboxane synthase with myocardial infarction in Uigur population of Xinjiang]. 2010 Zhonghua Yu Fang Yi Xue Za Zhi pmid:21215134
Ge Y et al. [Effect of ulinastatin on thromboxane Bâ‚‚ and deep vein thrombosis in elderly patients after hip joint replacement]. 2010 Zhong Nan Da Xue Xue Bao Yi Xue Ban pmid:21200097
Ferrante E et al. Determinants of thromboxane biosynthesis in rheumatoid arthritis: Role of RAGE and oxidant stress. 2010 Free Radic. Biol. Med. pmid:20541603
Antonino MJ et al. Antiplatelet effects of aspirin with phytosterols: comparison with non-enteric coated aspirin alone. 2010 Thromb. Res. pmid:19446864
Iwasaki W et al. Changes in the fatty acid composition of the liver with the administration of N-3 polyunsaturated fatty acids and the effects on warm ischemia/reperfusion injury in the rat liver. 2010 Shock pmid:19543146
Smock KJ and Rodgers GM Laboratory evaluation of aspirin responsiveness. 2010 Am. J. Hematol. pmid:20229592
Yao HX et al. [The study of relationship between platelet function and thrombus in patients with essential thrombocythaemia]. 2010 Zhonghua Yi Xue Za Zhi pmid:20356540