Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Nell A et al. | [Collection, preparation and storage of human plasma for radioimmunologic determination of thromboxane B2]. | 1988 | Wien. Klin. Wochenschr. | pmid:3242305 |
| Kaliman J et al. | [Venous prostacycline synthesis and plasma thromboxane B2 after low-dose aspirin]. | 1983 | Wien. Klin. Wochenschr. | pmid:6359724 |
| Wirthumer-Hoche C and Sinzinger H | [Protein binding of thromboxane--one of the sources of error in thromboxane determination]. | 1985 | Wien. Klin. Wochenschr. | pmid:3993037 |
| Sinzinger H et al. | [Defects in the prostaglandin system. IX. Lipoxygenase defect of thrombocytes in a patient with polycythemia vera]. | 1990 | Wien. Klin. Wochenschr. | pmid:2107637 |
| Burghuber OC et al. | Hydrogen peroxide induced pulmonary vasoconstriction in isolated rat lungs is attenuated by U60,257, a leucotriene synthesis blocker. | 1986 | Wien. Klin. Wochenschr. | pmid:3518246 |
| Gorczynska E et al. | [Effect of various stimulators on cyclooxygenase activity, platelet aggregation and TxB2 synthesis after using a platelet inhibitor (Aspro Clear) in vivo and in vitro]. | 1985 | Wiad. Lek. | pmid:3933184 |
| Glushko LV et al. | [An evaluation of the efficacy of antiatherosclerotic agents based on a study of the peripheral blood monocytes]. | 1990 | Vrach Delo | pmid:2168603 |
| Efimov VV and LadnyÄ AI | [Status of the prostacyclin and thromboxane system, lipid metabolism and lipid peroxidation processes in patients with coronary atherosclerosis]. | 1986 | Vrach Delo | pmid:3754994 |
| Aliavi AL | [Thrombocyte function and the prostacyclin-thromboxane system in patients with acute myocardial infarct]. | 1988 | Vrach Delo | pmid:3293319 |
| Bagdasarian A et al. | IVIG adverse reactions: potential role of cytokines and vasoactive substances. | 1998 | Vox Sang. | pmid:9501404 |
| Jacobi K et al. | Plasma levels of eicosanoids after transfusion of intraoperatively salvaged blood. | 2000 | Vox Sang. | pmid:10729809 |
| Bassalyk LS et al. | [The effect of indomethacin and leukinferon on the thromboxane B2 level in the blood plasma of patients with endometrial cancer in the perioperative period]. | 1992 | Vopr Onkol | pmid:1300754 |
| Malý J et al. | [Changes in platelet function in patients with arterial hypertension]. | 1995 | Vnitr Lek | pmid:7571480 |
| Spinarová L et al. | [Physical training in patients with chornic heart failure: haemodynamics, effects]. | 2001 | Vnitr Lek | pmid:15635849 |
| Margolis JH et al. | The efficacy of dexamethasone and flunixin meglumine in treating endotoxin-induced changes in calves. | 1987 | Vet. Res. Commun. | pmid:3445446 |
| Atroshi F et al. | Inflammation-related changes in cyclic AMP and cyclic GMP in bovine mastitis. | 1989 | Vet. Res. Commun. | pmid:2561035 |
| Cheng Z et al. | Pharmacokinetic and pharmacodynamic studies on phenylbutazone and oxyphenbutazone in goats. | 1997 | Vet. Rec. | pmid:9123796 |
| Friton GM et al. | Clinical and anti-inflammatory effects of treating endotoxin-challenged pigs with meloxicam. | 2006 | Vet. Rec. | pmid:17056651 |
| McKellar QA et al. | Flunixin pharmacokinetics and serum thromboxane inhibition in the dog. | 1989 | Vet. Rec. | pmid:2763429 |
| Galbraith EA and McKellar QA | Pharmacokinetics and pharmacodynamics of piroxicam in dogs. | 1991 | Vet. Rec. | pmid:1887556 |
| Mustonen K et al. | Dose-response investigation of oral ketoprofen in pigs challenged with Escherichia coli endotoxin. | 2012 | Vet. Rec. | pmid:22735989 |
| Banting A et al. | Efficacy of oral and parenteral ketoprofen in lactating cows with endotoxin-induced acute mastitis. | 2008 | Vet. Rec. | pmid:18953074 |
| Taylor PM et al. | Pharmacodynamics and pharmacokinetics of flunixin in the cat: a preliminary study. | 1991 | Vet. Rec. | pmid:2035219 |
| Giri SN et al. | Effects of endotoxin infusion on circulating levels of eicosanoids, progesterone, cortisol, glucose and lactic acid, and abortion in pregnant cows. | 1990 | Vet. Microbiol. | pmid:2407024 |
| Van de Weerdt ML et al. | Ketoprofen and phenylbutazone attenuation of PAF-induced lung inflammation in calves. | 1999 | Vet. J. | pmid:10030127 |
| Lees P et al. | Pharmacodynamics and pharmacokinetics of tolfenamic acid in ruminating calves: evaluation in models of acute inflammation. | 1998 | Vet. J. | pmid:9638074 |
| Maddens BE et al. | Validation of immunoassays for the candidate renal markers C-reactive protein, immunoglobulin G, thromboxane B2 and retinol binding protein in canine urine. | 2010 | Vet. Immunol. Immunopathol. | pmid:19815297 |
| Hall JA et al. | Dietary fish oil alters the lysophospholipid metabolomic profile and decreases urinary 11-dehydro thromboxane Bâ‚‚ concentration in healthy Beagles. | 2011 | Vet. Immunol. Immunopathol. | pmid:21925741 |
| Sigel MM et al. | Phylogenetic studies on lymphokines. Fish lymphocytes respond to human IL-1 and epithelial cells produce an IL-1 like factor. | 1986 | Vet. Immunol. Immunopathol. | pmid:3490047 |
| Peters SM et al. | In vivo characterization of inflammatory biomarkers in swine and the impact of flunixin meglumine administration. | 2012 | Vet. Immunol. Immunopathol. | pmid:22648045 |
| Bailey SR et al. | Plasma concentrations of endotoxin and platelet activation in the developmental stage of oligofructose-induced laminitis. | 2009 | Vet. Immunol. Immunopathol. | pmid:19091426 |
| Moore RM et al. | Effect of platelet-activating factor antagonist L-691,880 on low-flow ischemia-reperfusion injury of the large colon in horses. | 1998 Jan-Feb | Vet Surg | pmid:9449176 |
| Higgins AJ et al. | Actions of BW540C in an equine model of acute inflammation: a preliminary study. | 1987 | Vet Q | pmid:3039716 |
| Dinev D and Andonova M | The effect of general anesthesia and abdominal surgery upon plasma thromboxane B concentrations in horses. | 2004 | Vet Anaesth Analg | pmid:15053753 |
| Mullins KB et al. | Effects of carprofen, meloxicam and deracoxib on platelet function in dogs. | 2012 | Vet Anaesth Analg | pmid:22248445 |
| Brezitskaia ON and Sedov KR | [Status of the thrombocytic-vascular component of the hemostasis system in the population of the Far North]. | 1991 | Vestn. Akad. Med. Nauk SSSR | pmid:1801462 |
| Polkanov VS and Vinogradov AI | [The content of thromboxane B2 and 6-ketoprostaglandin F1 alpha of the blood plasma in patients with psoriasis and children with allergic dermatoses]. | 1989 | Vestn Dermatol Venerol | pmid:2718610 |
| Zhou Z et al. | Mechanisms underlying uridine adenosine tetraphosphate-induced vascular contraction in mouse aorta: Role of thromboxane and purinergic receptors. | 2015 | Vascul. Pharmacol. | pmid:25921923 |
| Miyamoto A et al. | Ibuprofen or ozagrel increases NO release and l-nitro arginine induces TXA(2) release from cultured porcine basilar arterial endothelial cells. | 2007 | Vascul. Pharmacol. | pmid:17113355 |
| González-Correa JA et al. | Gender differences in the effect of aspirin on retinal ischemia, prostanoid synthesis and nitric oxide production in experimental type 1-like diabetes. | 2007 Aug-Sep | Vascul. Pharmacol. | pmid:17581795 |
| Park WH et al. | Anti-inflammatory effects of a traditional Korean herbal formulation, Silsosangami, consisting of seven medicinal herbs: effect on hemolysis, neutrophil function, and gene expressions of iNOS and COX-2. | 2004 | Vascul. Pharmacol. | pmid:15664882 |
| Sinzinger H et al. | 20 mg aspirin daily--evidence for a clinical future of this extremely low-dose in arterial disease? | 1988 | VASA | pmid:3369232 |
| Strobl-Jäger E et al. | Platelet half-life in comparison to other in-vivo platelet function parameters such as thromboxane B2, beta-thromboglobulin and platelet factor 4 in patients with atherosclerotic lesions with and without hyperlipoproteinemia. | 1986 | VASA | pmid:2948337 |
| Ditter H and Matthias FR | Changes in thromboxane formation by platelets during and after a continuous endotoxin infusion into rabbits. | 1984 | VASA | pmid:6516562 |
| Fitscha P et al. | Follow-up of in-vivo platelet function (platelet half-life, thromboxane B2) in patients with coronary heart disease. | 1984 | VASA | pmid:6516563 |
| Rebrov BA | [Role of thromboxane A2 (B2) in the pathogenesis of stress proteinuria in healthy persons]. | 2001 Mar-Apr | Urologiia | pmid:11490711 |
| Frøkiaer J et al. | Renal blood flow and pelvic pressure after 4 weeks of total upper urinary tract obstruction in the pig. The effect of a TxA2 synthetase inhibitor on active preglomerular vasoconstriction. | 1988 | Urol. Res. | pmid:3413908 |
| Ali M et al. | Urothelial synthesis of prostanoids in the ovine ureter. | 1998 | Urol. Res. | pmid:9694598 |
| Greenstein A et al. | The role of oxygen free radicals and prostaglandins in reperfusion injury to warm ischemic kidneys. | 1991 | Urol. Res. | pmid:1759334 |
| RogovyÄ IuE | [Beta 2-microglobulin as a criterion of dysfunction in the regulation of proximal tubular activity in mercuric chloride-induced nephropathy]. | 1998 May-Jun | Urol Nefrol (Mosk) | pmid:9644989 |
| Jokela R et al. | Effect of in vitro stability of dietary fish oil on lipid peroxidation and prostanoids in vivo. | 1998 | Ups. J. Med. Sci. | pmid:10052110 |
| Persico N et al. | Transdermal HRT and Doppler findings in normotensive and hypertensive postmenopausal patients. | 2005 | Ultrasound Obstet Gynecol | pmid:16184506 |
| Komarevtseva IA et al. | [Change in prostanoid metabolism in cystic kidney lesion]. | 1997 Sep-Dec | Ukr. Biokhim. Zh. | pmid:9606841 |
| Midttun M et al. | [Thrombocyte aggregation and serum thromboxane in patients with acute myocardial infarction]. | 1990 | Ugeskr. Laeg. | pmid:2275044 |
| Lyck F et al. | [Thrombocyte aggregation and serum thromboxane B2 in patients with unstable angina pectoris treated with diltiazem or verapamil]. | 1992 | Ugeskr. Laeg. | pmid:1462402 |
| Weir MR et al. | Acute effects of intravenous cyclosporine on blood pressure, renal hemodynamics, and urine prostaglandin production of healthy humans. | 1990 | Transplantation | pmid:2301025 |
| Nassiri M et al. | Lymphoid organ production of immunomodulatory eicosanoids in mice resistant to neonatal tolerance induction. | 1994 | Transplantation | pmid:8009599 |
| Coffman TM et al. | Effect of dietary fish oil supplementation on eicosanoid production by rat renal allografts. | 1988 | Transplantation | pmid:3125638 |
| Ogata K et al. | Attenuation of ischemia and reperfusion injury of canine livers by inhibition of type II phospholipase A2 with LY329722. | 2001 | Transplantation | pmid:11374398 |
| Lane NJ et al. | Inhibition of leukotriene B4 synthesis does not prevent development of acute renal failure following storage and transplantation. | 1994 | Transplantation | pmid:7809921 |
| Ramos E et al. | The impact of arterialization on prostanoid generation after liver transplantation in the rat. | 1994 | Transplantation | pmid:8042232 |
| Fan TP et al. | Mechanism of action of cyclosporine in preventing cardiac allograft rejection. II. Graft tissue levels of prostacyclin and thromboxane. | 1987 | Transplantation | pmid:3547787 |
| Kawaguchi A et al. | Urinary thromboxane excretion in cardiac allograft rejection in immunosuppressed rats. | 1987 | Transplantation | pmid:3547788 |
| Capitanio A et al. | Detection of circulating released platelets after renal transplantation. | 1982 | Transplantation | pmid:6461116 |
| Gibbons CP et al. | Cortical and vascular prostaglandin synthesis during renal allograft rejection in the rat. | 1987 | Transplantation | pmid:3554639 |
| Garvin PJ et al. | Evaluation of the thromboxane A2 synthetase inhibitor OKY-046 in a warm ischemia-reperfusion rat model. | 1996 | Transplantation | pmid:8633364 |
| Balkhy HH et al. | Comparison of Eurocollins and University of Wisconsin solution in single flush preservation of the ischemic reperfused lung: an in vivo rabbit model. | 1995 | Transplantation | pmid:7732552 |
| Markewitz A et al. | Reduction of cyclosporine-induced nephrotoxicity by cilastatin following clinical heart transplantation. | 1994 | Transplantation | pmid:8154033 |
| Kim YI et al. | Hepatoprotection by a PGI2 analogue in complete warm ischemia of the pig liver. Prostanoid release from the reperfused liver. | 1994 | Transplantation | pmid:7940729 |
| Khirabadi BS et al. | Urine immunoreactive thromboxane B2 in rat cardiac allograft rejection. | 1985 | Transplantation | pmid:3880966 |
| Textor SC et al. | Systemic and renal hemodynamic differences between FK506 and cyclosporine in liver transplant recipients. | 1993 | Transplantation | pmid:7685934 |
| Petric R et al. | Amelioration of experimental cyclosporine nephrotoxicity by calcium channel inhibition. | 1992 | Transplantation | pmid:1465778 |
| Johnson BF et al. | Urinary thromboxane and 6-keto-prostaglandin F1 alpha are early markers of acute rejection in experimental pancreas transplantation. | 1994 | Transplantation | pmid:7518618 |
| Smith SR et al. | Chronic thromboxane synthase inhibition with CGS 12970 in human cyclosporine nephrotoxicity. | 1993 | Transplantation | pmid:8279014 |
| Johnson BF et al. | Thromboxane and prostacyclin synthesis in experimental pancreas transplantation. Changes in parenchymal and vascular prostanoids. | 1993 | Transplantation | pmid:8279018 |
| Proppe DG et al. | Diagnostic value of urinary thromboxane B2 concentration in detection of initial acute rejection reactions in human renal allografts. | 1995 | Transplantation | pmid:7709445 |
| Youngelman DF et al. | Effects of chronic cyclosporine administration on renal blood flow and intrarenal blood flow distribution. | 1991 | Transplantation | pmid:1994546 |
| Elzinga L et al. | Modification of experimental nephrotoxicity with fish oil as the vehicle for cyclosporine. | 1987 | Transplantation | pmid:3810835 |
| Coffman TM et al. | Evidence that renal prostaglandin and thromboxane production is stimulated in chronic cyclosporine nephrotoxicity. | 1987 | Transplantation | pmid:3810836 |
| Gladue RP and Newborg MF | The protective effects of the thromboxane synthetase inhibitor Dazmegrel on nephrotoxicity in cyclosporine-treated rats. | 1991 | Transplantation | pmid:1949170 |
| Santillan-Doherty P et al. | Urinary thromboxane B2 as an indicator of acute rejection in lung allotransplantation. | 1988 | Transplantation | pmid:3285529 |
| Post S et al. | Rapid increase in the activity of enzymes of eicosanoid synthesis in hepatic and extrahepatic tissues after experimental liver transplantation. | 1991 | Transplantation | pmid:1903222 |
| GarcÃa-Valdecasas JC et al. | Prostacyclin, thromboxane, and oxygen free radicals and postoperative liver function in human liver transplantation. | 1995 | Transplantation | pmid:7570973 |
| Hotter G et al. | Nitric oxide and arachidonate metabolism in ischemia-reperfusion associated with pancreas transplantation. | 1995 | Transplantation | pmid:7871573 |
| Moore TC et al. | Depression of peripheral lymph node lymphocyte traffic in sheep following central venous allogeneic whole-blood transfusion. | 1990 | Transplantation | pmid:1970202 |
| Suckfüll MM et al. | The contribution of endothelial cells to hyperacute rejection in xenogeneic perfused working hearts. | 1994 | Transplantation | pmid:8310518 |
| Post S et al. | Prostanoid release in experimental liver transplantation. | 1990 | Transplantation | pmid:2316009 |
| Schnabel FR et al. | The relationship of urinary thromboxane excretion to cyclosporine nephrotoxicity. | 1991 | Transplantation | pmid:2006526 |
| Ku K et al. | Influences of dietary omega-3 polyunsaturated fatty acids on the recovery of cardiac and renal functions after preservation in hyperlipidemic rats. | 1997 | Transplantation | pmid:9275102 |
| Klassen DK et al. | Effects of cyclosporine on human renal allograft renin and prostaglandin production. | 1989 | Transplantation | pmid:2660347 |
| Ruiz P et al. | Evidence that pretransplant donor blood transfusion prevents rat renal allograft dysfunction but not the in situ cellular alloimmune or morphologic manifestations of rejection. | 1988 | Transplantation | pmid:3276038 |
| Kawaguchi A et al. | Increase in urinary thromboxane B2 in rats caused by cyclosporine. | 1985 | Transplantation | pmid:4024243 |
| Pfeiffer S et al. | Hyperacute lung rejection in the pig-to-human model. III. Platelet receptor inhibitors synergistically modulate complement activation and lung injury. | 2003 | Transplantation | pmid:12698079 |
| Foegh ML et al. | Thromboxane and inflammatory cell infiltration of the allograft of renal transplant patients. | 1987 | Transplant. Proc. | pmid:3313875 |
| Su CL et al. | Inducible cyclooxygenase expression mediating hypoxia/reoxygenation-induced pulmonary vasoconstriction is attenuated by a cyclooxygenase inhibitor in rats. | 2012 | Transplant. Proc. | pmid:22564588 |
| WÅ‚odarczyk Z et al. | Effects of pentoxifylline treatment on delayed graft function in cadaveric kidney recipients. | 2000 | Transplant. Proc. | pmid:10995988 |
| Urade M et al. | Changes of thromboxane B2 level in experimental orthotopic liver transplantation in swines--the effect of warm ischemia and thromboxane A2 synthetase inhibition. | 1992 | Transplant. Proc. | pmid:1496677 |
| Pratschke J et al. | Allogeneic heart transplantation following xenografting. | 1992 | Transplant. Proc. | pmid:1566482 |
| Sinzinger H et al. | Platelet-derived growth factor and prostacyclin in kidney transplant rejection. | 1987 | Transplant. Proc. | pmid:3303560 |
| Foegh ML et al. | Differential effect of CGS 13080, a thromboxane synthase inhibitor, in suppressing serum and urine immunoreactive thromboxane B2 in kidney transplant patients. | 1988 | Transplant. Proc. | pmid:3279631 |