Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Shimizu T et al. | Up-regulation of Kv7.1 channels in thromboxane A2-induced colonic cancer cell proliferation. | 2014 | Pflugers Arch. | pmid:23995773 |
Mayer AM et al. | Vibrio vulnificus MO6-24/O lipopolysaccharide stimulates superoxide anion, thromboxane Bâ‚‚, matrix metalloproteinase-9, cytokine and chemokine release by rat brain microglia in vitro. | 2014 | Mar Drugs | pmid:24675728 |
van den Elsen LW et al. | Dietary fish oil improves endothelial function and lowers blood pressure via suppression of sphingolipid-mediated contractions in spontaneously hypertensive rats. | 2014 | J. Hypertens. | pmid:24569415 |
John F et al. | Elevated levels of leukotriene B4 and thromboxane B2 distinguish chest pain of cardiac and non cardiac origin. | 2013 May-Jun | Indian Heart J | pmid:23809385 |
Dudley A et al. | Cyclooxygenase expression and platelet function in healthy dogs receiving low-dose aspirin. | 2013 Jan-Feb | J. Vet. Intern. Med. | pmid:23278865 |
Maenthaisong R et al. | Clinical pharmacology of cyclooxygenase inhibition and pharmacodynamic interaction with aspirin by floctafenine in Thai healthy subjects. | 2013 Apr-Jun | Int J Immunopathol Pharmacol | pmid:23755755 |
Postula M et al. | Association of plasma concentrations of salicylic acid and high on ASA platelet reactivity in type 2 diabetes patients. | 2013 | Cardiol J | pmid:23558875 |
Honma S et al. | Amelioration of cisplatin-induced mouse renal lesions by a cyclooxygenase (COX)-2 selective inhibitor. | 2013 | Eur. J. Pharmacol. | pmid:23747596 |
Lee JJ et al. | Antithrombotic and antiplatelet activities of Soshiho-tang extract. | 2013 | BMC Complement Altern Med | pmid:23773779 |
Vazzana N et al. | Enhanced lipid peroxidation and platelet activation as potential contributors to increased cardiovascular risk in the low-HDL phenotype. | 2013 | J Am Heart Assoc | pmid:23557750 |
Dave M and Amin AR | Yin-Yang regulation of prostaglandins and nitric oxide by PGD2 in human arthritis: reversal by celecoxib. | 2013 | Immunol. Lett. | pmid:23603366 |
Hau CS et al. | Suppressive effects of antimycotics on thymic stromal lymphopoietin production in human keratinocytes. | 2013 | J. Dermatol. Sci. | pmid:23688403 |
Drew RC et al. | Aspirin augments carotid-cardiac baroreflex sensitivity during muscle mechanoreflex and metaboreflex activation in humans. | 2013 | J. Appl. Physiol. | pmid:23970529 |
An J et al. | Blocking of thromboxane Aâ‚‚ receptor attenuates airway mucus hyperproduction induced by cigarette smoke. | 2013 | Eur. J. Pharmacol. | pmid:23399768 |
Leclerc P et al. | Characterization of a human and murine mPGES-1 inhibitor and comparison to mPGES-1 genetic deletion in mouse models of inflammation. | 2013 | Prostaglandins Other Lipid Mediat. | pmid:24045148 |
Brose SA and Golovko MY | Eicosanoid post-mortem induction in kidney tissue is prevented by microwave irradiation. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:24113545 |
Matsunobu T et al. | Thromboxane A synthase-independent production of 12-hydroxyheptadecatrienoic acid, a BLT2 ligand. | 2013 | J. Lipid Res. | pmid:24009185 |
Barillà F et al. | Clopidogrel plus indobufen in acute coronary syndrome patients with hypersensitivity to aspirin undergoing percutaneous coronary intervention. | 2013 | Platelets | pmid:22646157 |
Lino-dos-Santos-Franco A et al. | Formaldehyde inhalation reduces respiratory mechanics in a rat model with allergic lung inflammation by altering the nitric oxide/cyclooxygenase-derived products relationship. | 2013 | Food Chem. Toxicol. | pmid:23871789 |
Xue J et al. | Inhibitory effects of Qushuanling Capsule () on thrombus formation and platelet aggregation in rats. | 2013 | Chin J Integr Med | pmid:23001461 |