Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Zaitsu M et al. | Induction of thromboxane A2 synthesizing enzymes in DMSO-induced granulocytic differentiation of HL-60 cells. | 2002 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12468261 |
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Celik I et al. | Effects of ibuprofen on the physiology and outcome of rabbit endotoxic shock. | 2002 | BMC Infect. Dis. | pmid:12445332 |
Leahy KM et al. | Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivo. | 2002 | Cancer Res. | pmid:11830509 |
Ozaki N et al. | Differential regulation of prostacyclin and thromboxane by dexamethasone and celecoxib during oxidative stress in newborn rabbits. | 2002 | Prostaglandins Other Lipid Mediat. | pmid:12428679 |
Ma LP et al. | Inhibition of platelet aggregation and expression of alpha granule membrane protein 140 and thromboxane B2 with pravastatin therapy for hypercholesterolemia. | 2002 | J Assoc Acad Minor Phys | pmid:11852667 |
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Bruno A et al. | Aspirin and urinary 11-dehydrothromboxane B(2) in African American stroke patients. | 2002 | Stroke | pmid:11779889 |
Canbaz M et al. | Effects of tibolone on thromboxane B(2) levels in postmenopausal women. | 2002 | Gynecol. Obstet. Invest. | pmid:11803222 |
Huang F et al. | Anti-platelet and anti-thrombotic effects of triacetylshikimic acid in rats. | 2002 | J. Cardiovasc. Pharmacol. | pmid:11791012 |
Jeng JH et al. | Modulation of platelet aggregation by areca nut and betel leaf ingredients: roles of reactive oxygen species and cyclooxygenase. | 2002 | Free Radic. Biol. Med. | pmid:11978487 |
Streppa HK et al. | Cyclooxygenase selectivity of nonsteroidal anti-inflammatory drugs in canine blood. | 2002 | Am. J. Vet. Res. | pmid:16206787 |
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Association between ibuprofen, aspirin therapy found. | 2002 | J Am Dent Assoc | pmid:12136787 | |
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Kiemer AK et al. | Inhibition of cyclooxygenase-2 by natriuretic peptides. | 2002 | Endocrinology | pmid:11861506 |
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