Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Diabetes, Gestational D016640 8 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Obesity, Morbid D009767 8 associated lipids
Fistula D005402 8 associated lipids
Arthus Reaction D001183 8 associated lipids
Mastitis, Bovine D008414 8 associated lipids
Renal Artery Obstruction D012078 8 associated lipids
Enteritis D004751 8 associated lipids
Fetal Diseases D005315 8 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Lupus Nephritis D008181 8 associated lipids
Arteriosclerosis Obliterans D001162 8 associated lipids
Salmonella Infections, Animal D012481 9 associated lipids
Hypertension, Renal D006977 9 associated lipids
Coronary Vasospasm D003329 9 associated lipids
Magnesium Deficiency D008275 9 associated lipids
Leukopenia D007970 9 associated lipids
Tooth, Impacted D014095 9 associated lipids
Thrombocythemia, Essential D013920 9 associated lipids
Carbon Monoxide Poisoning D002249 9 associated lipids
Mucocutaneous Lymph Node Syndrome D009080 9 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Cleft Palate D002972 9 associated lipids
Hypolipoproteinemias D007009 9 associated lipids
Bacteremia D016470 9 associated lipids
Rhinitis D012220 10 associated lipids
Hypertension, Renovascular D006978 10 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Retinal Detachment D012163 10 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Pneumonia D011014 10 associated lipids
Influenza, Human D007251 11 associated lipids
Shock D012769 11 associated lipids
Shock, Septic D012772 11 associated lipids
Pregnancy Complications, Cardiovascular D011249 11 associated lipids
Sepsis D018805 11 associated lipids
Acute Coronary Syndrome D054058 11 associated lipids
Venous Thrombosis D020246 11 associated lipids
Nephrotic Syndrome D009404 11 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Radiation Injuries, Experimental D011833 11 associated lipids
Byssinosis D002095 11 associated lipids
Meningioma D008579 11 associated lipids
Pregnancy Complications, Hematologic D011250 11 associated lipids
Migraine Disorders D008881 11 associated lipids
Liver Cirrhosis, Biliary D008105 12 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Blood Platelet Disorders D001791 12 associated lipids
Hypertension, Portal D006975 12 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Mistry M and Nasjletti A Role of TXA2 in the pathogenesis of severe angiotensin II-salt hypertension. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526469
Koshihara Y and Fukuda M Appearance of metabolic activities for arachidonate during development of mouse embryos. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526512
FitzGerald GA et al. Thromboxane biosynthesis and antagonism in humans. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2959047
Nowak J and FitzGerald GA In vivo formation of prostacyclin and thromboxane A2 at the site of platelet-vascular interaction in humans. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2959050
Gensini GF et al. Effects of dipyridamole infusion on local platelet aggregation and local formation of thromboxane A2 in patients with pulmonary hypertension. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159209
De Caterina R et al. Aspirin after acute myocardial infarction: a systematic approach to compare the hemostatic effects of three different doses. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159210
Trimarco B et al. Indomethacin blunts the late phase of nitroglycerin-induced coronary vasodilatation in dogs. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159220
Shikano M et al. Effects of selective thromboxane synthetase inhibitor OKY-046 on plasma prostaglandins in patients with coronary artery disease during exercise. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159226
Prosdocimi M et al. Prostacyclin and thromboxane levels during cardiac ischemia in dogs. 1985 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:3159235
Lecompte T et al. Interference of transmethylation inhibitors with thromboxane synthesis in rat platelets: evidence for the requirement of a methyl transfer reaction in platelet activation. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221560
Patrono C et al. Evidence for a renal origin of urinary thromboxane B2 in health and disease. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221569
Fletcher JR et al. Thromboxane inhibition in gram-negative sepsis fails to improve survival. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221586
Socini A et al. Fish oil administration lowers prostacyclin production and the antiaggregatory activity of aortic walls more effectively than platelet aggregation and thromboxane in the rat. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221591
Hornstra G et al. Dietary-fat-induced changes in the formation of prostanoids of the 2 and 3 series in relation to arterial thrombosis (rat) and atherosclerosis (rabbit). 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221593
Tremoli E et al. North Karelian study: changes in dietary fat reduce thromboxane B2 formation by platelets only in male subjects--preliminary report. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221594
Basso N et al. Gastric mucosal prostaglandin generation in rats with stress ulcer. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221618
Foegh M et al. Prostacyclin and thromboxane release from human peritoneal macrophages. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221630
Westwick J et al. Inhibition of thromboxane formation prevents endotoxin-induced renal fibrin deposition in jaundiced rats. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221642
Patrignani P et al. Characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases. 1995 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:7732817
Foegh ML et al. Urinary thromboxane has diagnostic value in myocardial infarction. 1995 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:7732879