Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Lupus Nephritis D008181 8 associated lipids
Arteriosclerosis Obliterans D001162 8 associated lipids
Peripheral Vascular Diseases D016491 8 associated lipids
Arthritis, Juvenile D001171 8 associated lipids
Diabetes, Gestational D016640 8 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Obesity, Morbid D009767 8 associated lipids
Fistula D005402 8 associated lipids
Fetal Diseases D005315 8 associated lipids
Arthus Reaction D001183 8 associated lipids
Mastitis, Bovine D008414 8 associated lipids
Renal Artery Obstruction D012078 8 associated lipids
Hypolipoproteinemias D007009 9 associated lipids
Cleft Palate D002972 9 associated lipids
Leukopenia D007970 9 associated lipids
Bacteremia D016470 9 associated lipids
Salmonella Infections, Animal D012481 9 associated lipids
Hypertension, Renal D006977 9 associated lipids
Coronary Vasospasm D003329 9 associated lipids
Tooth, Impacted D014095 9 associated lipids
Thrombocythemia, Essential D013920 9 associated lipids
Carbon Monoxide Poisoning D002249 9 associated lipids
Mucocutaneous Lymph Node Syndrome D009080 9 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Magnesium Deficiency D008275 9 associated lipids
Rhinitis D012220 10 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Pneumonia D011014 10 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Hypertension, Renovascular D006978 10 associated lipids
Retinal Detachment D012163 10 associated lipids
Pregnancy Complications, Hematologic D011250 11 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Migraine Disorders D008881 11 associated lipids
Influenza, Human D007251 11 associated lipids
Shock D012769 11 associated lipids
Shock, Septic D012772 11 associated lipids
Pregnancy Complications, Cardiovascular D011249 11 associated lipids
Acute Coronary Syndrome D054058 11 associated lipids
Venous Thrombosis D020246 11 associated lipids
Nephrotic Syndrome D009404 11 associated lipids
Sepsis D018805 11 associated lipids
Radiation Injuries, Experimental D011833 11 associated lipids
Byssinosis D002095 11 associated lipids
Meningioma D008579 11 associated lipids
Death, Sudden D003645 12 associated lipids
Liver Cirrhosis, Biliary D008105 12 associated lipids
Arterial Occlusive Diseases D001157 12 associated lipids
Blood Platelet Disorders D001791 12 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Chen L et al. Cyclooxygenase inhibition decreases nitric oxide synthase activity in human platelets. 1997 Am. J. Physiol. pmid:9362253
Barton MH et al. Effects of pentoxifylline infusion on response of horses to in vivo challenge exposure with endotoxin. 1997 Am. J. Vet. Res. pmid:9361896
Baskett A et al. Effect of pentoxifylline, flunixin meglumine, and their combination on a model of endotoxemia in horses. 1997 Am. J. Vet. Res. pmid:9361895
Lahoz C et al. Effects of dietary fat saturation on eicosanoid production, platelet aggregation and blood pressure. 1997 Eur. J. Clin. Invest. pmid:9352251
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Supanz S et al. Effects of the novel thromboxane (TXA2) receptor antagonist linotroban on inulin and para-aminohippuric acid clearances in the conscious male and female rat. 1997 Arzneimittelforschung pmid:9342416
Zahavi M and Zahavi J Concomitant in vitro platelet hypofunction and increased thromboxane B2 (TXB2) generation and enhanced in vivo platelet activation. A distinct syndrome in thrombosis? 1997 Eur. J. Haematol. pmid:9338626
Chavali SR et al. Decreased production of interleukin-1-beta, prostaglandin-E2 and thromboxane-B2, and elevated levels of interleukin-6 and -10 are associated with increased survival during endotoxic shock in mice consuming diets enriched with sesame seed oil supplemented with Quil-A saponin. 1997 Int. Arch. Allergy Immunol. pmid:9338609
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Swails WS et al. Effect of a fish oil structured lipid-based diet on prostaglandin release from mononuclear cells in cancer patients after surgery. 1997 Sep-Oct JPEN J Parenter Enteral Nutr pmid:9323688
Berlin I et al. [Comparison between effects of morning and evening administration of effervescent calcium carbasalate (equivalent of 160 mg aspirin) on the gastroduodenal mucosa in healthy volunteers]. 1997 Pathol. Biol. pmid:9309270
Tanaka M et al. Effects of a thromboxane synthetase inhibitor (OKY-046) in an ischemia-reperfusion model of intrauterine growth retardation in Sprague-Dawley rats. 1997 Biol. Neonate pmid:9303217
Abate A et al. Inhibition of mediator release from anaphylactic guinea pig hearts by the novel phospholipase A2 inhibitor 3-(4-octadecylbenzoyl) acrylic acid. 1997 Inflamm. Res. pmid:9297549
Trang LE et al. Levels of prostaglandins F2 alpha and E2 and thromboxane B2 in joint fluid in rheumatoid arthritis. 1977 Scand. J. Rheumatol. pmid:929121
Cipollone F et al. Differential suppression of thromboxane biosynthesis by indobufen and aspirin in patients with unstable angina. 1997 Circulation pmid:9286937
Santillan-Doherty P et al. Plasma thromboxane B2 concentrations and pulmonary vascular resistance during lung reperfusion. 1997 Jul-Aug J Invest Surg pmid:9284000
Freese R and Mutanen M Alpha-linolenic acid and marine long-chain n-3 fatty acids differ only slightly in their effects on hemostatic factors in healthy subjects. 1997 Am. J. Clin. Nutr. pmid:9280178