Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Canales A et al. | The effect of consuming meat enriched in walnut paste on platelet aggregation and thrombogenesis varies in volunteers with different apolipoprotein A4 genotype. | 2010 Sep-Oct | Nutr Hosp | pmid:21336431 |
Fuchs I et al. | Platelet hyperfunction is decreased by additional aspirin loading in patients presenting with myocardial infarction on daily aspirin therapy. | 2010 | Crit. Care Med. | pmid:20400900 |
Steib CJ et al. | Intraperitoneal LPS amplifies portal hypertension in rat liver fibrosis. | 2010 | Lab. Invest. | pmid:20212458 |
Dragani A et al. | The contribution of cyclooxygenase-1 and -2 to persistent thromboxane biosynthesis in aspirin-treated essential thrombocythemia: implications for antiplatelet therapy. | 2010 | Blood | pmid:19887674 |
Kienzler JL et al. | Systemic bioavailability of topical diclofenac sodium gel 1% versus oral diclofenac sodium in healthy volunteers. | 2010 | J Clin Pharmacol | pmid:19841157 |
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Zisman E et al. | Platelet function recovery after cessation of aspirin: preliminary study of volunteers and surgical patients. | 2010 | Eur J Anaesthesiol | pmid:20035230 |
Oldenhof J et al. | Effect of maximum OTC doses of naproxen sodium or acetaminophen on low-dose aspirin inhibition of serum thromboxane B2. | 2010 | Curr Med Res Opin | pmid:20429831 |
Dharmasaroja PA and Sae-Lim S | Effects of different doses, enteric-coated preparation of aspirin, and sex on urinary 11-dehydrothromboxane B2 in healthy volunteers. | 2010 | Blood Coagul. Fibrinolysis | pmid:20689403 |
Milara J et al. | Cigarette smoke exposure up-regulates endothelin receptor B in human pulmonary artery endothelial cells: molecular and functional consequences. | 2010 | Br. J. Pharmacol. | pmid:20698855 |
Anauate MC et al. | Effect of isolated fractions of Harpagophytum procumbens D.C. (devil's claw) on COX-1, COX-2 activity and nitric oxide production on whole-blood assay. | 2010 | Phytother Res | pmid:20812280 |
Yassine HN et al. | Clinical determinants of aspirin resistance in diabetes. | 2010 | Diabetes Res. Clin. Pract. | pmid:20719400 |
Würtz M et al. | Patients with previous definite stent thrombosis have a reduced antiplatelet effect of aspirin and a larger fraction of immature platelets. | 2010 | JACC Cardiovasc Interv | pmid:20723855 |
Qu C et al. | Chronic inhibition of nitric-oxide synthase potentiates endothelium-dependent contractions in the rat aorta by augmenting the expression of cyclooxygenase-2. | 2010 | J. Pharmacol. Exp. Ther. | pmid:20444882 |
Warner JH et al. | Adaptive regression modeling of biomarkers of potential harm in a population of U.S. adult cigarette smokers and nonsmokers. | 2010 | BMC Med Res Methodol | pmid:20233412 |
Wang BZ et al. | [Association of the Pro1770Leu polymorphism in CYP5A1 gene with myocardial infarction in Uigur population of Xinjiang]. | 2010 | Zhonghua Yi Xue Yi Chuan Xue Za Zhi | pmid:20931532 |
Santilli F et al. | Postprandial hyperglycemia is a determinant of platelet activation in early type 2 diabetes mellitus. | 2010 | J. Thromb. Haemost. | pmid:20088941 |
Yao HX et al. | [The study of relationship between platelet function and thrombus in patients with essential thrombocythaemia]. | 2010 | Zhonghua Yi Xue Za Zhi | pmid:20356540 |