Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Cheng Y and Li ZK | [Changes of neurotransmitter endothelin, thromboxance B2 and 6-keto-prostaglandin F1 alpha in patients with chronic pulmonary heart disease]. | 2010 | Nan Fang Yi Ke Da Xue Xue Bao | pmid:20584647 |
Boutaud O and Oates JA | Study of inhibitors of the PGH synthases for which potency is regulated by the redox state of the enzymes. | 2010 | Methods Mol. Biol. | pmid:20645166 |
Kawaguchi T et al. | The human megakaryocytic cell line UT-7/TPO expresses functional platelet agonist signals mediated through GPVI and thromboxane receptor. | 2010 | Cell Biol. Int. | pmid:20522022 |
Alusik S et al. | The inhibitory effect of statins on urinary 11-dehydrothromboxane levels. | 2010 | Int Angiol | pmid:20502413 |
Mangalpally KK et al. | Platelet activation patterns in platelet size sub-populations: differential responses to aspirin in vitro. | 2010 | J. Thromb. Thrombolysis | pmid:20502945 |
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Youssef DT et al. | New anti-inflammatory sterols from the Red Sea sponges Scalarispongia aqabaensis and Callyspongia siphonella. | 2010 | Nat Prod Commun | pmid:20184014 |
Kidson-Gerber G et al. | Serum thromboxane B2 compared to five other platelet function tests for the evaluation of aspirin effect in stable cardiovascular disease. | 2010 | Heart Lung Circ | pmid:20144559 |
Butler BD et al. | Circadian study of decompression sickness symptoms and response-associated variables in rats. | 2010 | Chronobiol. Int. | pmid:20205563 |
Liu H et al. | Aspirin inhibits fractalkine expression in atherosclerotic plaques and reduces atherosclerosis in ApoE gene knockout mice. | 2010 | Cardiovasc Drugs Ther | pmid:19997773 |
Cavalca V et al. | Simultaneous quantification of 8-iso-prostaglandin-F(2alpha) and 11-dehydro thromboxane B(2) in human urine by liquid chromatography-tandem mass spectrometry. | 2010 | Anal. Biochem. | pmid:19825360 |
Laguta PS et al. | [Aspirin resistance in patients with stable ischemic heart disease]. | 2010 | Kardiologiia | pmid:21526557 |
Ren R et al. | Protective effects of Danshensu on liver injury induced by omethoate in rats. | 2010 | Toxicol. Mech. Methods | pmid:20843270 |
Watanabe H et al. | [Thromboxane A2 (TXA2), thromboxane B2(TXB2)]. | 2010 | Nippon Rinsho | pmid:20963856 |
Hepgül G et al. | Preventive effect of pentoxifylline on acute radiation damage via antioxidant and anti-inflammatory pathways. | 2010 | Dig. Dis. Sci. | pmid:19294507 |
Yen PL et al. | Effects of deep-frying oil on blood pressure and oxidative stress in spontaneously hypertensive and normotensive rats. | 2010 | Nutrition | pmid:19592221 |
Huntjens DR et al. | Impact of chronic inflammation on the pharmacokinetic-pharmacodynamic relationship of naproxen. | 2010 | Eur J Pain | pmid:19679500 |
Addad F et al. | Response variability to aspirin and one-year prediction of vascular events in patients with stable coronary artery disease. | 2010 | J. Thromb. Thrombolysis | pmid:19381450 |
De La Cruz JP et al. | Virgin olive oil administration improves the effect of aspirin on retinal vascular pattern in experimental diabetes mellitus. | 2010 | Br. J. Nutr. | pmid:20350343 |
Smock KJ and Rodgers GM | Laboratory evaluation of aspirin responsiveness. | 2010 | Am. J. Hematol. | pmid:20229592 |