Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Fetal Diseases D005315 8 associated lipids
Enteritis D004751 8 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Lupus Nephritis D008181 8 associated lipids
Arteriosclerosis Obliterans D001162 8 associated lipids
Peripheral Vascular Diseases D016491 8 associated lipids
Arthritis, Juvenile D001171 8 associated lipids
Diabetes, Gestational D016640 8 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Obesity, Morbid D009767 8 associated lipids
Fistula D005402 8 associated lipids
Arthus Reaction D001183 8 associated lipids
Carbon Monoxide Poisoning D002249 9 associated lipids
Mucocutaneous Lymph Node Syndrome D009080 9 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Hypolipoproteinemias D007009 9 associated lipids
Cleft Palate D002972 9 associated lipids
Bacteremia D016470 9 associated lipids
Salmonella Infections, Animal D012481 9 associated lipids
Hypertension, Renal D006977 9 associated lipids
Coronary Vasospasm D003329 9 associated lipids
Magnesium Deficiency D008275 9 associated lipids
Leukopenia D007970 9 associated lipids
Tooth, Impacted D014095 9 associated lipids
Thrombocythemia, Essential D013920 9 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Retinal Detachment D012163 10 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Pneumonia D011014 10 associated lipids
Hypertension, Renovascular D006978 10 associated lipids
Rhinitis D012220 10 associated lipids
Meningioma D008579 11 associated lipids
Radiation Injuries, Experimental D011833 11 associated lipids
Byssinosis D002095 11 associated lipids
Pregnancy Complications, Hematologic D011250 11 associated lipids
Migraine Disorders D008881 11 associated lipids
Influenza, Human D007251 11 associated lipids
Shock D012769 11 associated lipids
Shock, Septic D012772 11 associated lipids
Pregnancy Complications, Cardiovascular D011249 11 associated lipids
Sepsis D018805 11 associated lipids
Acute Coronary Syndrome D054058 11 associated lipids
Venous Thrombosis D020246 11 associated lipids
Nephrotic Syndrome D009404 11 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Arterial Occlusive Diseases D001157 12 associated lipids
Cat Diseases D002371 12 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Shen AY et al. Inhibition of 2-P-mercaptophenyl-1,4-naphthoquinone on human platelet function. 1999 Life Sci. pmid:10403492
Jönsson A et al. Effects of amide local anaesthetics on eicosanoid formation in burned skin. 1999 Acta Anaesthesiol Scand pmid:10408815
Morrow JD et al. Increased formation of thromboxane in vivo in humans with mastocytosis. 1999 J. Invest. Dermatol. pmid:10417625
Mercer JB et al. The effect of short-term cold exposure on risk factors for cardiovascular disease. 1999 Thromb. Res. pmid:10418798
Kawano K et al. Superiority of platelet integrin GPIIb-IIIa receptor antagonist over aspirin in preventing cyclic flow reductions in the guinea pig middle cerebral artery. 1999 Eur. J. Pharmacol. pmid:10422782
McCowan LM et al. Administration of low-dose aspirin to mothers with small for gestational age fetuses and abnormal umbilical Doppler studies to increase birthweight: a randomised double-blind controlled trial. 1999 Br J Obstet Gynaecol pmid:10428519
Hamberg M et al. A method for measurement of platelet regeneration in man. 1978 Prostaglandins Med pmid:104315
Mills JL et al. Prostacyclin and thromboxane changes predating clinical onset of preeclampsia: a multicenter prospective study. 1999 JAMA pmid:10432033
Kim HS et al. Effects of tetrandrine and fangchinoline on human platelet aggregation and thromboxane B2 formation. 1999 J Ethnopharmacol pmid:10433485
van Kooten F et al. Increased thromboxane biosynthesis is associated with poststroke dementia. 1999 Stroke pmid:10436098
Ricetti MM et al. Effects of sodium selenite on in vitro interactions between platelets and endothelial cells. 1999 Int. J. Clin. Lab. Res. pmid:10436266
Tsugawa K et al. A selective cyclo-oxygenase-2 inhibitor, NS-398, may improve portal hypertension without inducing gastric mucosal injury. 1999 J. Gastroenterol. Hepatol. pmid:10440208
Licker M et al. Chronic angiotensin converting inhibition does not influence renal hemodynamic and function during cardiac surgery. 1999 Can J Anaesth pmid:10442956
Ogura S et al. Protective effect of tyrphostin AG-556 on shock induced by endotoxin or gram positive bacteria. 1999 Shock pmid:10446890
Zhang S et al. Effects of acupuncture on the levels of endothelin, TXB2, and 6-keto-PGF1 alpha in apoplexy patients. 1999 J Tradit Chin Med pmid:10453582
Arakida Y et al. Effects of lipid mediator antagonists on predominant mediator-controlled asthmatic reactions in passively sensitized guinea pigs. 1999 J. Pharmacol. Exp. Ther. pmid:10454505
Melton SM et al. Mediator-dependent secondary injury after unilateral blunt thoracic trauma. 1999 Shock pmid:10454828
Sheu JR et al. The antiplatelet activity of PMC, a potent alpha-tocopherol analogue, is mediated through inhibition of cyclo-oxygenase. 1999 Br. J. Pharmacol. pmid:10455267
Jiménez R et al. Involvement of thromboxane A2 in the endothelium-dependent contractions induced by myricetin in rat isolated aorta. 1999 Br. J. Pharmacol. pmid:10455307
Hino Y et al. Changes in endothelium-derived vascular regulatory factors during dobutamine-stress-induced silent myocardial ischemia in patients with Kawasaki disease. 1999 Jpn. Circ. J. pmid:10462014