Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Nagao T et al. | Effect of lipo-prostaglandin E1 on crescentic-type anti-glomerular basement membrane nephritis in rats. | 1998 | Eur. J. Pharmacol. | pmid:9650829 |
Harada Y et al. | Differing profiles of prostaglandin formation inhibition between selective prostaglandin H synthase-2 inhibitors and conventional NSAIDs in inflammatory and non-inflammatory sites of the rat. | 1998 | Prostaglandins Other Lipid Mediat. | pmid:9653772 |
Bordia A et al. | Effect of garlic (Allium sativum) on blood lipids, blood sugar, fibrinogen and fibrinolytic activity in patients with coronary artery disease. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9654398 |
Schuligoi R et al. | Effects of the cyclooxygenase-2 inhibitor NS-398 on thromboxane and leukotriene synthesis in rat peritoneal cells. | 1998 | Inflamm. Res. | pmid:9657255 |
Aoki T et al. | Difference of (Ca2+)i movements in platelets stimulated by thrombin and TRAP: the involvement of alpha(IIb)beta3-mediated TXA2 synthesis. | 1998 | Thromb. Haemost. | pmid:9657446 |
Bode-Böger SM et al. | Chronic dietary supplementation with L-arginine inhibits platelet aggregation and thromboxane A2 synthesis in hypercholesterolaemic rabbits in vivo. | 1998 | Cardiovasc. Res. | pmid:9659460 |
Adler S and Bollu R | Glomerular endothelial cell injury mediated by shiga-like toxin-1. | 1998 | Kidney Blood Press. Res. | pmid:9661132 |
Geertsen PF et al. | Renal haemodynamics, sodium and water reabsorption during continuous intravenous infusion of recombinant interleukin-2. | 1998 | Clin. Sci. | pmid:9662488 |
Kunitoh H et al. | A double-blind, placebo-controlled trial of the thromboxane synthetase blocker OKY-046 on bronchial hypersensitivity in bronchial asthma patients. | 1998 | J Asthma | pmid:9669829 |
Sheu JR et al. | Inhibitory mechanisms of naloxone on human platelets. | 1998 Jul-Aug | Clin. Exp. Pharmacol. Physiol. | pmid:9673433 |
Miyamoto A et al. | The role of thromboxane A2 in regulating porcine basilar arterial tone. | 1998 | J. Vet. Pharmacol. Ther. | pmid:9673964 |
Cheng Z et al. | Measurement of cyclooxygenase inhibition in vivo: a study of two non-steroidal anti-inflammatory drugs in sheep. | 1998 | Inflammation | pmid:9675607 |
Onizuka M et al. | Suppression of prostanoid formation and regulation of peripheral circulation after surgery using thrombin inhibitor (MD805). | 1998 | Surg. Today | pmid:9681611 |
De La Cruz JP et al. | Effect of camonagrel, a selective thromboxane synthase inhibitor, on retinal vascularization in experimental diabetes. | 1998 | Eur. J. Pharmacol. | pmid:9683018 |
Tewes KS et al. | Measurement of thromboxane B2 in platelet-rich human plasma by gas chromatography-mass spectrometry and gas chromatography-tandem mass spectrometry following extractive pentafluorobenzyl esterification. | 1998 | Anal. Biochem. | pmid:9683522 |
Stephenson AH et al. | 5,6-Epoxyeicosatrienoic acid reduces increases in pulmonary vascular resistance in the dog. | 1998 | Am. J. Physiol. | pmid:9688901 |
Bell JG et al. | Growth, mortality, tissue histopathology and fatty acid compositions, eicosanoid production and response to stress, in juvenile turbot fed diets rich in gamma-linolenic acid in combination with eicosapentaenoic acid or docosahexaenoic acid. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9690713 |
Napoli E and Franco N | [Thromboxane A2 production in the pathogenesis of diabetic complications]. | 1998 | Minerva Endocrinol. | pmid:9691631 |
Lebel B et al. | Inhibition of mediator release from dispersed nasal polyp cells by cyclosporin A. | 1998 | Int. Arch. Allergy Immunol. | pmid:9693278 |
Ali M et al. | Urothelial synthesis of prostanoids in the ovine ureter. | 1998 | Urol. Res. | pmid:9694598 |