Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Shock, Septic D012772 11 associated lipids
Pregnancy Complications, Cardiovascular D011249 11 associated lipids
Sepsis D018805 11 associated lipids
Acute Coronary Syndrome D054058 11 associated lipids
Venous Thrombosis D020246 11 associated lipids
Nephrotic Syndrome D009404 11 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Meningioma D008579 11 associated lipids
Radiation Injuries, Experimental D011833 11 associated lipids
Byssinosis D002095 11 associated lipids
Pregnancy Complications, Hematologic D011250 11 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Hypertension, Renovascular D006978 10 associated lipids
Rhinitis D012220 10 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Retinal Detachment D012163 10 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Pneumonia D011014 10 associated lipids
Salmonella Infections, Animal D012481 9 associated lipids
Hypertension, Renal D006977 9 associated lipids
Coronary Vasospasm D003329 9 associated lipids
Magnesium Deficiency D008275 9 associated lipids
Leukopenia D007970 9 associated lipids
Tooth, Impacted D014095 9 associated lipids
Thrombocythemia, Essential D013920 9 associated lipids
Carbon Monoxide Poisoning D002249 9 associated lipids
Mucocutaneous Lymph Node Syndrome D009080 9 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Hypolipoproteinemias D007009 9 associated lipids
Cleft Palate D002972 9 associated lipids
Bacteremia D016470 9 associated lipids
Lupus Nephritis D008181 8 associated lipids
Arteriosclerosis Obliterans D001162 8 associated lipids
Peripheral Vascular Diseases D016491 8 associated lipids
Arthritis, Juvenile D001171 8 associated lipids
Diabetes, Gestational D016640 8 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Obesity, Morbid D009767 8 associated lipids
Fistula D005402 8 associated lipids
Arthus Reaction D001183 8 associated lipids
Mastitis, Bovine D008414 8 associated lipids
Renal Artery Obstruction D012078 8 associated lipids
Fetal Diseases D005315 8 associated lipids
Enteritis D004751 8 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Biliary Tract Neoplasms D001661 7 associated lipids
Femoral Fractures D005264 7 associated lipids
Raynaud Disease D011928 7 associated lipids
Bronchopneumonia D001996 7 associated lipids
Tachycardia D013610 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Kosik-Bogacka DI et al. The inflammatory effect of infection with Hymenolepis diminuta via the increased expression and activity of COX-1 and COX-2 in the rat jejunum and colon. 2016 Exp. Parasitol. pmid:27466058
Pallio G et al. Use of a balanced dual cyclooxygenase-1/2 and 5-lypoxygenase inhibitor in experimental colitis. 2016 Eur. J. Pharmacol. pmid:27450484
Peng LL et al. Associations of MDR1, TBXA2R, PLA2G7, and PEAR1 genetic polymorphisms with the platelet activity in Chinese ischemic stroke patients receiving aspirin therapy. 2016 Acta Pharmacol. Sin. pmid:27641736
Mayer AM et al. Classical and Alternative Activation of Cyanobacterium Oscillatoria sp. Lipopolysaccharide-Treated Rat Microglia in vitro. 2016 Toxicol. Sci. pmid:26609141
Olszowski T et al. The Effect of Cadmium on COX-1 and COX-2 Gene, Protein Expression, and Enzymatic Activity in THP-1 Macrophages. 2015 Biol Trace Elem Res pmid:25645360
Korbecki J et al. Cyclooxygenase-1 as the main source of proinflammatory factors after sodium orthovanadate treatment. 2015 Biol Trace Elem Res pmid:25398544
Al-Husseini A et al. Increased eicosanoid levels in the Sugen/chronic hypoxia model of severe pulmonary hypertension. 2015 PLoS ONE pmid:25785937
Mateu A et al. Cross-talk between TLR4 and PPARγ pathways in the arachidonic acid-induced inflammatory response in pancreatic acini. 2015 Int. J. Biochem. Cell Biol. pmid:26510582
Liu TF et al. [Correlation between the level of the urinary 11-dehydrothromboxane B2 and the clinical efficacy of aspirin in patients with type 2 diabetes and coronary artery disease]. 2015 Beijing Da Xue Xue Bao pmid:26679651
Holland B et al. Pharmacokinetics and pharmacodynamics of three formulations of firocoxib in healthy horses. 2015 J. Vet. Pharmacol. Ther. pmid:25378135
Lüdicke F et al. A Japanese cross-sectional multicentre study of biomarkers associated with cardiovascular disease in smokers and non-smokers. 2015 Biomarkers pmid:26616146
Violi F et al. Reply: platelets interplay between pneumonia and cardiovascular events: establishing a link? 2015 J. Am. Coll. Cardiol. pmid:25857919
Khan AR et al. Platelet activation and myocardial infarction in patients with pneumonia: are statins the answer? 2015 J. Am. Coll. Cardiol. pmid:25857918
Gavriilaki E et al. Platelets interplay between pneumonia and cardiovascular events: establishing a link? 2015 J. Am. Coll. Cardiol. pmid:25857917
Véricel E et al. Moderate oral supplementation with docosahexaenoic acid improves platelet function and oxidative stress in type 2 diabetic patients. 2015 Thromb. Haemost. pmid:25832443
Khanna V et al. Does the response to aspirin and clopidogrel vary over 6 months in patients with ischemic heart disease? 2015 J. Thromb. Haemost. pmid:25809653
Wu F et al. Valsartan decreases platelet activity and arterial thrombotic events in elderly patients with hypertension. 2015 Chin. Med. J. pmid:25591555
Paikin JS et al. Multiple daily doses of acetyl-salicylic acid (ASA) overcome reduced platelet response to once-daily ASA after coronary artery bypass graft surgery: a pilot randomized controlled trial. 2015 J. Thromb. Haemost. pmid:25546465
Bautista-Pérez R et al. Involvement of neutral sphingomyelinase in the angiotensin II signaling pathway. 2015 Am. J. Physiol. Renal Physiol. pmid:25354938
Drew RC et al. Healthy older humans exhibit augmented carotid-cardiac baroreflex sensitivity with aspirin during muscle mechanoreflex and metaboreflex activation. 2015 Am. J. Physiol. Heart Circ. Physiol. pmid:26371168