Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Shock, Septic D012772 11 associated lipids
Pregnancy Complications, Cardiovascular D011249 11 associated lipids
Sepsis D018805 11 associated lipids
Acute Coronary Syndrome D054058 11 associated lipids
Venous Thrombosis D020246 11 associated lipids
Nephrotic Syndrome D009404 11 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Meningioma D008579 11 associated lipids
Radiation Injuries, Experimental D011833 11 associated lipids
Byssinosis D002095 11 associated lipids
Pregnancy Complications, Hematologic D011250 11 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Hypertension, Renovascular D006978 10 associated lipids
Rhinitis D012220 10 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Retinal Detachment D012163 10 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Pneumonia D011014 10 associated lipids
Salmonella Infections, Animal D012481 9 associated lipids
Hypertension, Renal D006977 9 associated lipids
Coronary Vasospasm D003329 9 associated lipids
Magnesium Deficiency D008275 9 associated lipids
Leukopenia D007970 9 associated lipids
Tooth, Impacted D014095 9 associated lipids
Thrombocythemia, Essential D013920 9 associated lipids
Carbon Monoxide Poisoning D002249 9 associated lipids
Mucocutaneous Lymph Node Syndrome D009080 9 associated lipids
Sleep Apnea, Obstructive D020181 9 associated lipids
Hypolipoproteinemias D007009 9 associated lipids
Cleft Palate D002972 9 associated lipids
Bacteremia D016470 9 associated lipids
Lupus Nephritis D008181 8 associated lipids
Arteriosclerosis Obliterans D001162 8 associated lipids
Peripheral Vascular Diseases D016491 8 associated lipids
Arthritis, Juvenile D001171 8 associated lipids
Diabetes, Gestational D016640 8 associated lipids
Carotid Artery Injuries D020212 8 associated lipids
Obesity, Morbid D009767 8 associated lipids
Fistula D005402 8 associated lipids
Arthus Reaction D001183 8 associated lipids
Mastitis, Bovine D008414 8 associated lipids
Renal Artery Obstruction D012078 8 associated lipids
Fetal Diseases D005315 8 associated lipids
Enteritis D004751 8 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Biliary Tract Neoplasms D001661 7 associated lipids
Femoral Fractures D005264 7 associated lipids
Raynaud Disease D011928 7 associated lipids
Bronchopneumonia D001996 7 associated lipids
Tachycardia D013610 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Shimizu T et al. Up-regulation of Kv7.1 channels in thromboxane A2-induced colonic cancer cell proliferation. 2014 Pflugers Arch. pmid:23995773
Mayer AM et al. Vibrio vulnificus MO6-24/O lipopolysaccharide stimulates superoxide anion, thromboxane Bâ‚‚, matrix metalloproteinase-9, cytokine and chemokine release by rat brain microglia in vitro. 2014 Mar Drugs pmid:24675728
van den Elsen LW et al. Dietary fish oil improves endothelial function and lowers blood pressure via suppression of sphingolipid-mediated contractions in spontaneously hypertensive rats. 2014 J. Hypertens. pmid:24569415
John F et al. Elevated levels of leukotriene B4 and thromboxane B2 distinguish chest pain of cardiac and non cardiac origin. 2013 May-Jun Indian Heart J pmid:23809385
Dudley A et al. Cyclooxygenase expression and platelet function in healthy dogs receiving low-dose aspirin. 2013 Jan-Feb J. Vet. Intern. Med. pmid:23278865
Maenthaisong R et al. Clinical pharmacology of cyclooxygenase inhibition and pharmacodynamic interaction with aspirin by floctafenine in Thai healthy subjects. 2013 Apr-Jun Int J Immunopathol Pharmacol pmid:23755755
Postula M et al. Association of plasma concentrations of salicylic acid and high on ASA platelet reactivity in type 2 diabetes patients. 2013 Cardiol J pmid:23558875
Honma S et al. Amelioration of cisplatin-induced mouse renal lesions by a cyclooxygenase (COX)-2 selective inhibitor. 2013 Eur. J. Pharmacol. pmid:23747596
Lee JJ et al. Antithrombotic and antiplatelet activities of Soshiho-tang extract. 2013 BMC Complement Altern Med pmid:23773779
Kim YJ Rhamnetin attenuates melanogenesis by suppressing oxidative stress and pro-inflammatory mediators. 2013 Biol. Pharm. Bull. pmid:23739488
Dave M and Amin AR Yin-Yang regulation of prostaglandins and nitric oxide by PGD2 in human arthritis: reversal by celecoxib. 2013 Immunol. Lett. pmid:23603366
Hau CS et al. Suppressive effects of antimycotics on thymic stromal lymphopoietin production in human keratinocytes. 2013 J. Dermatol. Sci. pmid:23688403
Drew RC et al. Aspirin augments carotid-cardiac baroreflex sensitivity during muscle mechanoreflex and metaboreflex activation in humans. 2013 J. Appl. Physiol. pmid:23970529
An J et al. Blocking of thromboxane Aâ‚‚ receptor attenuates airway mucus hyperproduction induced by cigarette smoke. 2013 Eur. J. Pharmacol. pmid:23399768
Leclerc P et al. Characterization of a human and murine mPGES-1 inhibitor and comparison to mPGES-1 genetic deletion in mouse models of inflammation. 2013 Prostaglandins Other Lipid Mediat. pmid:24045148
Brose SA and Golovko MY Eicosanoid post-mortem induction in kidney tissue is prevented by microwave irradiation. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:24113545
Matsunobu T et al. Thromboxane A synthase-independent production of 12-hydroxyheptadecatrienoic acid, a BLT2 ligand. 2013 J. Lipid Res. pmid:24009185
Barillà F et al. Clopidogrel plus indobufen in acute coronary syndrome patients with hypersensitivity to aspirin undergoing percutaneous coronary intervention. 2013 Platelets pmid:22646157
Lino-dos-Santos-Franco A et al. Formaldehyde inhalation reduces respiratory mechanics in a rat model with allergic lung inflammation by altering the nitric oxide/cyclooxygenase-derived products relationship. 2013 Food Chem. Toxicol. pmid:23871789
Xue J et al. Inhibitory effects of Qushuanling Capsule () on thrombus formation and platelet aggregation in rats. 2013 Chin J Integr Med pmid:23001461