Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Keratitis D007634 7 associated lipids
Jejunal Diseases D007579 3 associated lipids
Intermittent Claudication D007383 6 associated lipids
Influenza, Human D007251 11 associated lipids
Inflammation D007249 119 associated lipids
Infertility D007246 3 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Hypothyroidism D007037 32 associated lipids
Hypotension D007022 41 associated lipids
Hypolipoproteinemias D007009 9 associated lipids
Hypertension, Renovascular D006978 10 associated lipids
Hypertension, Renal D006977 9 associated lipids
Hypertension, Pulmonary D006976 32 associated lipids
Hypertension, Portal D006975 12 associated lipids
Hypertension D006973 115 associated lipids
Hypersensitivity D006967 22 associated lipids
Hyperlipoproteinemia Type IV D006953 6 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hyperemia D006940 25 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hypercapnia D006935 5 associated lipids
Hyperalgesia D006930 42 associated lipids
Hyperaldosteronism D006929 4 associated lipids
Hydatidiform Mole D006828 3 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemorrhagic Fever with Renal Syndrome D006480 3 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Hemolysis D006461 131 associated lipids
Heart Valve Diseases D006349 4 associated lipids
Heart Septal Defects D006343 2 associated lipids
Heart Failure D006333 36 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Rhinitis, Allergic, Seasonal D006255 7 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Glomerulosclerosis, Focal Segmental D005923 4 associated lipids
Glomerulonephritis, IGA D005922 7 associated lipids
Glomerulonephritis D005921 35 associated lipids
Glioma D005910 112 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Gastritis D005756 27 associated lipids
Frostbite D005627 1 associated lipids
Foot Rot D005535 1 associated lipids
Fistula D005402 8 associated lipids
Fibrosis D005355 23 associated lipids
Fibromuscular Dysplasia D005352 2 associated lipids
Fever D005334 35 associated lipids
Fetal Diseases D005315 8 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Böhm E et al. 11-Dehydro-thromboxane B2, a stable thromboxane metabolite, is a full agonist of chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) in human eosinophils and basophils. 2004 J. Biol. Chem. pmid:14668348
Persico N et al. Transdermal hormone replacement therapy and Doppler findings in normal and overweight postmenopausal patients. 2004 Gynecol. Endocrinol. pmid:15726916
Gross GJ and Moore J Effect of COX-1/COX-2 inhibition versus selective COX-2 inhibition on coronary vasodilator responses to arachidonic acid and acetylcholine. 2004 Pharmacology pmid:15161995
Suzuki N et al. Quantitative liquid chromatography-tandem mass spectrometric analysis of 11-dehydro TXB2 in urine. 2004 Prostaglandins Other Lipid Mediat. pmid:15165035
Kudolo GB et al. The ingestion of Ginkgo biloba extract (EGb 761) inhibits arachidonic acid-mediated platelet aggregation and thromboxane B2 production in healthy volunteers. 2004 J Herb Pharmacother pmid:15927922
Moriguchi A et al. Antithrombotic effects of FK419, a novel nonpeptide platelet GPIIb/IIIa antagonist, in a guinea pig photochemically induced middle cerebral artery thrombosis model: comparison with ozagrel and argatroban. 2004 J. Pharmacol. Exp. Ther. pmid:14634048
Dey A et al. Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria. 2004 Obes. Res. pmid:15340111
Sheu JR et al. Expression of matrix metalloproteinase-9 in human platelets: regulation of platelet activation in in vitro and in vivo studies. 2004 Br. J. Pharmacol. pmid:15289295
Toth B et al. Insights into the role of interleukin-6 in the induction of hepatic injury after trauma-hemorrhagic shock. 2004 J. Appl. Physiol. pmid:15298985
Craft JA et al. Increased platelet-derived microparticles in the coronary circulation of percutaneous transluminal coronary angioplasty patients. 2004 Blood Coagul. Fibrinolysis pmid:15311156
Devi MM and Das UN Effect of prostaglandins against alloxan-induced cytotoxicity to insulin secreting insulinoma RIN cells in vitro. 2004 Prostaglandins Leukot. Essent. Fatty Acids pmid:15380818
Ferroni P et al. Platelet activation in type 2 diabetes mellitus. 2004 J. Thromb. Haemost. pmid:15304032
Di Nunno L et al. Novel synthesis of 3,4-diarylisoxazole analogues of valdecoxib: reversal cyclooxygenase-2 selectivity by sulfonamide group removal. 2004 J. Med. Chem. pmid:15369392
Mak IT et al. Cardiac pathologic effects of azidothymidine (AZT) in Mg-deficient mice. 2004 Cardiovasc. Toxicol. pmid:15371632
Valeri CR et al. In vitro effects of poly-N-acetyl glucosamine on the activation of platelets in platelet-rich plasma with and without red blood cells. 2004 J Trauma pmid:15280746
Singer P and Wirth M Can n-3 PUFA reduce cardiac arrhythmias? Results of a clinical trial. 2004 Prostaglandins Leukot. Essent. Fatty Acids pmid:15253884
Barbieri SS et al. Apocynin prevents cyclooxygenase 2 expression in human monocytes through NADPH oxidase and glutathione redox-dependent mechanisms. 2004 Free Radic. Biol. Med. pmid:15203187
Kojima F et al. Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis. 2004 Arthritis Res. Ther. pmid:15225371
Zhang L et al. Effects of thiol antioxidant on reduced nicotinamide adenine dinucleotide phosphate oxidase in hypertensive Dahl salt-sensitive rats. 2004 Free Radic. Biol. Med. pmid:15528040
Harizi H et al. Inhibition of IL-6, TNF-alpha, and cyclooxygenase-2 protein expression by prostaglandin E2-induced IL-10 in bone marrow-derived dendritic cells. 2004 Cell. Immunol. pmid:15219461
Zhang C et al. Inhibition of inflammation contributes to organ protection of atenolol in sinoaortic-denervated rats. 2004 J. Cardiovasc. Pharmacol. pmid:15071353
Bruno A et al. Serial urinary 11-dehydrothromboxane B2, aspirin dose, and vascular events in blacks after recent cerebral infarction. 2004 Stroke pmid:14963281
Kwak SH et al. Effects of propofol on endotoxin-induced acute lung injury in rabbit. 2004 J. Korean Med. Sci. pmid:14966342
Scott G et al. Lumiracoxib: pharmacokinetic and pharmacodynamic profile when coadministered with fluconazole in healthy subjects. 2004 J Clin Pharmacol pmid:14747429
Arrebola MM et al. In vitro effects of clopidogrel on the platelet-subendothelium interaction, platelet thromboxane and endothelial prostacyclin production, and nitric oxide synthesis. 2004 J. Cardiovasc. Pharmacol. pmid:14668571
de La Puerta Vázquez R et al. Effects of different dietary oils on inflammatory mediator generation and fatty acid composition in rat neutrophils. 2004 Metab. Clin. Exp. pmid:14681843
Freitas CF et al. Role of endothelin-1 and thromboxane A2 in the pulmonary hypertension induced by heparin-protamine interaction in anesthetized dogs. 2004 J. Cardiovasc. Pharmacol. pmid:14668575
Cotter G et al. Lack of aspirin effect: aspirin resistance or resistance to taking aspirin? 2004 Am. Heart J. pmid:14760328
von Aulock S et al. Granulocyte colony-stimulating factor (filgrastim) treatment primes for increased ex vivo inducible prostanoid release. 2004 J. Pharmacol. Exp. Ther. pmid:14610236
Minuz P et al. Determinants of platelet activation in human essential hypertension. 2004 Hypertension pmid:14656953
Park WH et al. Anti-inflammatory effects of a traditional Korean herbal formulation, Silsosangami, consisting of seven medicinal herbs: effect on hemolysis, neutrophil function, and gene expressions of iNOS and COX-2. 2004 Vascul. Pharmacol. pmid:15664882
Vainio M et al. Prostacyclin, thromboxane A and the effect of low-dose ASA in pregnancies at high risk for hypertensive disorders. 2004 Acta Obstet Gynecol Scand pmid:15548142
Capone ML et al. Clinical pharmacology of platelet, monocyte, and vascular cyclooxygenase inhibition by naproxen and low-dose aspirin in healthy subjects. 2004 Circulation pmid:15037526
Liu P et al. [Effects of the extracts from decoction for resuscitation and its component herbs on PGI2, TXA2 and NO release from rat vascular endothelial cells under hypoxia in vitro]. 2004 Zhongguo Zhong Yao Za Zhi pmid:15631091
Yang JP et al. [Changes of the platelet function and serum anticardiolipin antibody in patients with pulmonary thromboembolism]. 2004 Zhonghua Jie He He Hu Xi Za Zhi pmid:15634381
Wang MS et al. [The effects of lupus anticoagulant on pulmonary thromboembolism]. 2004 Zhonghua Jie He He Hu Xi Za Zhi pmid:15634384
Franz KB A functional biological marker is needed for diagnosing magnesium deficiency. 2004 J Am Coll Nutr pmid:15637224
Ganafa AA et al. Amlodipine attenuates oxidative stress-induced hypertension. 2004 Am. J. Hypertens. pmid:15363814
Díaz AM et al. Phenylpropanoid glycosides from Scrophularia scorodonia: in vitro anti-inflammatory activity. 2004 Life Sci. pmid:15010262
Tsai CY et al. Proinflammatory cytokines enhance COX-1 gene expression in cultured rat glomerular mesangial cells. 2004 Int. Immunopharmacol. pmid:14975359
Smalling WE et al. Protective effect of pentoxifylline on volume-induced lung injury in newborn piglets. 2004 Biol. Neonate pmid:14981352
Ikonomidis I et al. Reduction of daily life ischaemia by aspirin in patients with angina: underlying link between thromboxane A2 and macrophage colony stimulating factor. 2004 Heart pmid:15020512
Dippel DW et al. What is the lowest dose of aspirin for maximum suppression of in vivo thromboxane production after a transient ischemic attack or ischemic stroke? 2004 Cerebrovasc. Dis. pmid:15026612
Rotondo S et al. Licofelone, an inhibitor of cyclooxygenase and 5-lipoxygenase, specifically inhibits cyclooxygenase-1-dependent platelet activation. 2004 Eur. J. Pharmacol. pmid:15044038
Guay J et al. Carrageenan-induced paw edema in rat elicits a predominant prostaglandin E2 (PGE2) response in the central nervous system associated with the induction of microsomal PGE2 synthase-1. 2004 J. Biol. Chem. pmid:15044444
Véricel E et al. Diabetic patients without vascular complications display enhanced basal platelet activation and decreased antioxidant status. 2004 Diabetes pmid:15047620
Yugar-Toledo JC et al. Uncontrolled hypertension, uncompensated type II diabetes, and smoking have different patterns of vascular dysfunction. 2004 Chest pmid:15006938
Akbiyik F et al. Human bone marrow megakaryocytes and platelets express PPARgamma, and PPARgamma agonists blunt platelet release of CD40 ligand and thromboxanes. 2004 Blood pmid:15130939
Kawada N et al. TP receptors regulate renal hemodynamics during angiotensin II slow pressor response. 2004 Am. J. Physiol. Renal Physiol. pmid:15213069
Peck OM et al. Staphylococcus aureus and lipopolysaccharide induce homologous tolerance but heterologous priming: role of interferon-gamma. 2004 Shock pmid:14770039