Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Keratitis D007634 7 associated lipids
Jejunal Diseases D007579 3 associated lipids
Intermittent Claudication D007383 6 associated lipids
Influenza, Human D007251 11 associated lipids
Inflammation D007249 119 associated lipids
Infertility D007246 3 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Hypothyroidism D007037 32 associated lipids
Hypotension D007022 41 associated lipids
Hypolipoproteinemias D007009 9 associated lipids
Hypertension, Renovascular D006978 10 associated lipids
Hypertension, Renal D006977 9 associated lipids
Hypertension, Pulmonary D006976 32 associated lipids
Hypertension, Portal D006975 12 associated lipids
Hypertension D006973 115 associated lipids
Hypersensitivity D006967 22 associated lipids
Hyperlipoproteinemia Type IV D006953 6 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hyperemia D006940 25 associated lipids
Hyperlipoproteinemia Type II D006938 22 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Hypercapnia D006935 5 associated lipids
Hyperalgesia D006930 42 associated lipids
Hyperaldosteronism D006929 4 associated lipids
Hydatidiform Mole D006828 3 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemorrhagic Fever with Renal Syndrome D006480 3 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
Hemolysis D006461 131 associated lipids
Heart Valve Diseases D006349 4 associated lipids
Heart Septal Defects D006343 2 associated lipids
Heart Failure D006333 36 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Rhinitis, Allergic, Seasonal D006255 7 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Glomerulosclerosis, Focal Segmental D005923 4 associated lipids
Glomerulonephritis, IGA D005922 7 associated lipids
Glomerulonephritis D005921 35 associated lipids
Glioma D005910 112 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Gastritis D005756 27 associated lipids
Frostbite D005627 1 associated lipids
Foot Rot D005535 1 associated lipids
Fistula D005402 8 associated lipids
Fibrosis D005355 23 associated lipids
Fibromuscular Dysplasia D005352 2 associated lipids
Fever D005334 35 associated lipids
Fetal Diseases D005315 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Mitchell MD et al. Possible role for prostacyclin in human parturition. 1978 Prostaglandins pmid:373020
Cerskus AL et al. Effects of indomethacin and sulfinpyrazone on in vivo formation of thromboxane B2 and prostaglandin D2 during arachidonate infusion in rabbits. 1978 Thromb. Res. pmid:653641
Mitchell MD et al. Thromboxane B2 in amniotic fluid before and during labour. 1978 Br J Obstet Gynaecol pmid:656348
Raz A et al. Biosynthesis of thromboxane B2 and 12-L-hydroxy-5,8,10-heptadecatrienoic acid in human platelets. Evidence for a common enzymatic pathway. 1978 Eur. J. Biochem. pmid:658053
Salmon JA A radioimmunoassay for 6-keto-prostaglandin F1alpha. 1978 Prostaglandins pmid:663275
Davidson EM et al. The release of thromboxane B2 by rabbit peritoneal polymorphonuclear leucocytes [proceedings]. 1978 Br. J. Pharmacol. pmid:667479
Goldstein IM et al. Thromboxane generation by human peripheral blood polymorphonuclear leukocytes. 1978 J. Exp. Med. pmid:702055
Anhut H et al. Pharmacological modification of thromboxane and prostaglandin release in cardiac anaphylaxis. 1978 Prostaglandins pmid:704912
Nelson NA et al. Synthesis of thromboxane B2 metabolites. 1978 Prostaglandins pmid:704927
Marion J and Wolfe LS Increase in vivo of unesterified fatty acids, prostaglandin F2 alpha but not thromboxane B2 in rat brain during drug induced convulsions. 1978 Prostaglandins pmid:704928
Anhut H et al. Release of 15-keto-13, 14-dihydro-thromboxane B2 and prostaglandin D2 during anaphylaxis as measured by radioimmunoassay. 1978 Naunyn Schmiedebergs Arch. Pharmacol. pmid:740052
McMillan RM et al. Malonaldehyde formation in intact platelets is catalysed by thromboxane synthase. 1978 Biochem. J. pmid:743261
Chignard M et al. Synthesis of thromboxane B2 in incubates of dog platelet-rich plasma with arachidonic acid and its inhibition by different drugs. 1978 Biochem. Biophys. Res. Commun. pmid:743319
Mitchell MD and Robinson JS Concentrations of 6-oxo-prostaglandin F1 alpha and thromboxane B2 in the tracheal fluid of foetal sheep. 1978 J. Endocrinol. pmid:744937
Agradi E et al. Influence of short term dietary supplementation of different lipids on aggregation and arachidonic acid metabolism in rabbit platelets. 1978 Prostaglandins pmid:748984
Fitzpatrick FA and Gorman RR A comparison of imidazole and 9,11-azoprosta-5,13-dienoic acid. Two selective thromboxane synthetase inhibitors. 1978 Biochim. Biophys. Acta pmid:629996
Malik KU Prostaglandin-mediated inhibition of the vasoconstrictor responses of the isolated perfused art splenic vasculature to adrenergic stimuli. 1978 Circ. Res. pmid:27321
Hamberg M et al. A method for measurement of platelet regeneration in man. 1978 Prostaglandins Med pmid:104315
Best LC et al. Dipyridamole and platelet function. 1978 Lancet pmid:81402
Adcock JJ et al. The mechanism of enhancement by fatty acid hydroperoxides of anaphylactic mediator release. 1978 Prostaglandins pmid:81495