Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

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Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Disseminated Intravascular Coagulation D004211 7 associated lipids
Uveitis D014605 14 associated lipids
Byssinosis D002095 11 associated lipids
Enteritis D004751 8 associated lipids
Pneumonia, Aspiration D011015 3 associated lipids
Periapical Periodontitis D010485 6 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Arthus Reaction D001183 8 associated lipids
Angina Pectoris D000787 27 associated lipids
Angina, Unstable D000789 14 associated lipids
Vascular Diseases D014652 16 associated lipids
Pregnancy Complications, Hematologic D011250 11 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Ascites D001201 25 associated lipids
Albuminuria D000419 18 associated lipids
Anemia D000740 21 associated lipids
Chediak-Higashi Syndrome D002609 4 associated lipids
Heart Valve Diseases D006349 4 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Coronary Vasospasm D003329 9 associated lipids
Scleroderma, Systemic D012595 16 associated lipids
Keratitis D007634 7 associated lipids
Mastitis, Bovine D008414 8 associated lipids
Celiac Disease D002446 16 associated lipids
Rhinitis, Allergic, Seasonal D006255 7 associated lipids
Placenta Diseases D010922 5 associated lipids
Salmonella Infections, Animal D012481 9 associated lipids
Raynaud Disease D011928 7 associated lipids
Nephritis D009393 19 associated lipids
Bartter Syndrome D001477 5 associated lipids
Respiration Disorders D012120 5 associated lipids
Renal Artery Obstruction D012078 8 associated lipids
Hypolipoproteinemias D007009 9 associated lipids
Carotid Stenosis D016893 15 associated lipids
Influenza, Human D007251 11 associated lipids
Bronchopneumonia D001996 7 associated lipids
Facial Pain D005157 5 associated lipids
Abortion, Habitual D000026 5 associated lipids
Eye Burns D005126 13 associated lipids
Retinal Detachment D012163 10 associated lipids
Cleft Palate D002972 9 associated lipids
Choline Deficiency D002796 16 associated lipids
Leiomyosarcoma D007890 4 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Atrial Fibrillation D001281 16 associated lipids
Coronary Thrombosis D003328 7 associated lipids
Glomerulonephritis, Membranous D015433 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Abdullah NA and Assem ES Ischaemia and mediator release: interrelationship in antigen-challenged sensitized guinea-pig kidney. 1990 Agents Actions pmid:1695424
Berti F et al. Immune release of histamine and other lipid mediators from guinea-pig isolated kidney: antagonism by BN-52021. 1990 Agents Actions pmid:1696776
Ghanem NS et al. The cardiac and renal effects of the complement fragment C5a des Arg are partly mediated by the release of histamine and arachidonic acid metabolites. 1989 Agents Actions pmid:2473617
Nosál R et al. Effect of chloroquine on isolated mast cells. 1991 Agents Actions pmid:1716835
Zatta A et al. At low extracellular calcium concentration platelet activating factor induces beta-thromboglobulin release from human platelets through thromboxane-endoperoxides formation. 1987 Agents Actions pmid:2961218
Cifone MG et al. Stimulatory effect of hr tumor necrosis factor on TxB2 release by polymorphonuclears and macrophages. 1986 Agents Actions pmid:3825754
Carr DP et al. Comparison of the systemic inhibition of thromboxane synthesis, anti-inflammatory activity and gastro-intestinal toxicity of non-steroidal anti-inflammatory drugs in the rat. 1986 Agents Actions pmid:3825757
Conti P et al. Augmentation of thromboxane production in vitro by polymorphonuclears and macrophages exposed to IL1/LP. 1986 Agents Actions pmid:3485895
Srivastava R et al. Prostanoid mediated effects of centchroman, a non-steroidal oral contraceptive. 1986 Agents Actions pmid:3532722
Conti P et al. Effect of supernatants from PHA-stimulated and non-stimulated lymphocyte cultures on thromboxane B2 release by polymorphonuclear leukocytes in vitro. 1985 Agents Actions pmid:4003201
Atzori L et al. Vasoconstriction and bronchoconstriction induced by 2,5-di-(tert-butyl)1,4-benzohydroquinone, an endoplasmic reticular Ca2+-ATPase inhibitor, in isolated and perfused rat lung. 1992 Agents Actions pmid:1414686
Ghanem NS and Assem ES Comparison of the release of various mediators from atrial and ventricular tissues of sensitized guinea-pig hearts. 1987 Agents Actions pmid:2440280
de Clerck F et al. Inhibition of 5-hydroxytryptamine-induced and -amplified human platelet aggregation by ketanserin (R 41 468), a selective 5-HT2-receptor antagonist. 1982 Agents Actions pmid:6215842
Nosál R et al. Antihistaminic drug bromadryl and stimulated platelet aggregation. 1994 Agents Actions pmid:7976789
de Clerck F et al. Inhibition of 5-hydroxytryptamine-induced and -amplified human platelet aggregation by ketanserin (R 41,468), a selective 5-HT2-receptor antagonist. 1982. 1994 Agents Actions pmid:7725978
De Clerck F et al. Platelet activation by endogenous 5-hydroxytryptamine and histamine released by mast cell degranulation with compound 48/80 in the rat. 1983 Agents Actions pmid:6858790
Seitz M et al. The influence of synovial fluid from patients with rheumatoid arthritis on the proliferation of peripheral blood lymphocytes and the prostanoid release from monocytes. 1981 Agents Actions pmid:7340450
Prancan A et al. Platelet thromboxane production during endotoxin shock. 1981 Agents Actions pmid:7340458
Chignard M et al. Arachidonate-mediated bronchoconstriction and platelet activation are inhibited by microgram doses of compound L8027 which are not selective for thromboxane synthetase. 1979 Agents Actions Suppl. pmid:291306
Peskar BA and Holland A Plasma levels of immunoreactive 15-keto-13,14-dihydro-thromboxane B2 in guinea pigs during anaphylaxis and after histamine injection. 1979 Agents Actions Suppl. pmid:294148