Thromboxane b2
Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
Cross Reference
Introduction
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thromboxane b2?
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
PubChem Associated disorders and diseases
What pathways are associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thromboxane b2?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Thromboxane b2?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
What genes are associated with Thromboxane b2?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thromboxane b2?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thromboxane b2
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Clark IA and Hunt NH | Increased production of arachidonate metabolites by peritoneal cells of mice infected with Plasmodium vinckei vinckei. | 1986 | Aust J Exp Biol Med Sci | pmid:3579736 |
| Bjøro K et al. | Formation of prostanoids in human umbilical vessels perfused in vitro. | 1986 | Prostaglandins | pmid:3523623 |
| Bjøro K | Prostacyclin and thromboxane formation in human umbilical arteries following stimulation with vasoactive autacoids. | 1986 | Prostaglandins | pmid:3523624 |
| Zhang L | [Effect of pollen typhae on 6-keto-PGF1 alpha, TXB2, TC and HDL-C in chronic hyperlipemic rabbits]. | 1986 | Zhonghua Xin Xue Guan Bing Za Zhi | pmid:3582146 |
| Schleimer RP et al. | Selective inhibition of arachidonic acid metabolite release from human lung tissue by antiinflammatory steroids. | 1986 | J. Immunol. | pmid:3082976 |
| Winther K and Hedman C | Beta-adrenoceptor blockade, platelets, and rheologic factors. | 1986 | Cephalalgia | pmid:2879630 |
| Chiricolo M et al. | Prostaglandin and thromboxane biosynthesis in resting and activated platelet-free monocytes from aged subjects. | 1986 | Gerontology | pmid:3086183 |
| Laustiola K et al. | Adrenaline infusion evokes increased thromboxane B2 production by platelets in healthy men: the effect of beta-adrenoceptor blockade. | 1986 | Eur. J. Clin. Invest. | pmid:2881786 |
| Tripp CS et al. | Monocyte migration explains the changes in macrophage arachidonate metabolism during the immune response. | 1986 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3099288 |
| Perico N et al. | Effect of short-term cyclosporine administration in rats on renin-angiotensin and thromboxane A2: possible relevance to the reduction in glomerular filtration rate. | 1986 | J. Pharmacol. Exp. Ther. | pmid:3531461 |
| Miller JL et al. | Characterization of a platelet membrane protein of low molecular weight associated with platelet activation following binding by monoclonal antibody AG-1. | 1986 | Blood | pmid:2943333 |
| Fischer S et al. | Formation of prostacyclin and thromboxane in man as measured by the main urinary metabolites. | 1986 | Biochim. Biophys. Acta | pmid:3754157 |
| Wang Z et al. | [Na [125I]-labelled 6-keto-PGF1 alpha and thromboxane B2]. | 1986 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:2943448 |
| Quilley CP and Rifkind AB | Prostaglandin release by the chick embryo heart is increased by 2,3,7,8-tetrachlorodibenzo-p-dioxin and by other cytochrome P-448 inducers. | 1986 | Biochem. Biophys. Res. Commun. | pmid:3085671 |
| Ogino M et al. | Plasma thromboxane and prostacyclin: comparison during normal pregnancy and pregnancy complicated by hypertension. | 1986 | Endocrinol. Jpn. | pmid:3530728 |
| Pekonen F et al. | Platelet function and coagulation in normal and preeclamptic pregnancy. | 1986 | Thromb. Res. | pmid:2944245 |
| Rich S | Primary pulmonary hypertension: recent advances. | 1986 | Herz | pmid:3530928 |
| Beitz J et al. | Influence of a cod liver oil diet in healthy and insulin-dependent diabetic volunteers on fatty acid pattern, inhibition of prostacyclin formation by low density lipoprotein (LDL) and platelet thromboxane. | 1986 | Klin. Wochenschr. | pmid:3531705 |
| Sinzinger H et al. | [Prostacyclin- and thromboxane synthesis in the vascular wall after gammatron irradiation]. | 1986 | Strahlenther Onkol | pmid:3532388 |
| Srivastava R et al. | Prostanoid mediated effects of centchroman, a non-steroidal oral contraceptive. | 1986 | Agents Actions | pmid:3532722 |
| Fitzgerald DJ et al. | Platelet activation in unstable coronary disease. | 1986 | N. Engl. J. Med. | pmid:3531859 |
| Tomoda H | Development of an experimental model of acute myocardial infarction and the effects of a thromboxane synthetase inhibitor (OKY-046). | 1986 | Am. Heart J. | pmid:3532743 |
| Tanaka Y et al. | [Detection of 6-keto-prostaglandin F1 alpha and thromboxane B2 in human placental tissues]. | 1986 | Nippon Sanka Fujinka Gakkai Zasshi | pmid:3534121 |
| Goldberg RN et al. | Effects of a leukotriene antagonist on the early hemodynamic manifestations of group B streptococcal sepsis in piglets. | 1986 | Pediatr. Res. | pmid:3534778 |
| Schenkein HA | LPS-stimulated release of prostaglandin E and thromboxane B2 from the U937 cell line. | 1986 | Cell. Immunol. | pmid:3100058 |
| Honey AC et al. | Effect of indomethacin and dazoxiben on intravascular platelet aggregation in the anaesthetized rabbit. | 1986 | Thromb. Haemost. | pmid:3775692 |
| Maurin N | Routine measurement of thromboxane B2 and the prostacyclin metabolite 6-keto-prostaglandin F1 alpha in plasma. | 1986 | Arzneimittelforschung | pmid:3778554 |
| Dratewka-Kos E et al. | Unsaturated fatty acids inhibit ADP- arachidonate-induced platelet aggregation without affecting thromboxane synthesis. | 1986 | Biochem. Cell Biol. | pmid:3778664 |
| Hubbell JA and McIntire LV | Visualization and analysis of mural thrombogenesis on collagen, polyurethane and nylon. | 1986 | Biomaterials | pmid:3778995 |
| Honzlová M and Starý S | [Eicosanoids and rheumatic disease]. | 1986 | Cas. Lek. Cesk. | pmid:3779779 |
| Noonan TC et al. | Mechanism of peptidoleukotriene-induced increases in pulmonary transvascular fluid filtration. | 1986 | J. Appl. Physiol. | pmid:3781998 |
| Zhu L et al. | [Effects of sodium beta-3,4-dihydroxyphenyl lactate and beta-phenyl lactic acid on prostacycline and thromboxane A2 contents in the plasma of rabbits after coronary artery occlusion]. | 1986 | Zhongguo Yao Li Xue Bao | pmid:2955643 |
| Simonson MS and Dunn MJ | Leukotriene C4 and D4 contract rat glomerular mesangial cells. | 1986 | Kidney Int. | pmid:3465969 |
| Conti P et al. | In vitro enhanced thromboxane B2 release by polymorphonuclear leukocytes and macrophages after treatment with human recombinant interleukin 1. | 1986 | Prostaglandins | pmid:3489956 |
| Sigel MM et al. | Phylogenetic studies on lymphokines. Fish lymphocytes respond to human IL-1 and epithelial cells produce an IL-1 like factor. | 1986 | Vet. Immunol. Immunopathol. | pmid:3490047 |
| Konturek SJ et al. | Double blind controlled study on the effect of sucralfate on gastric prostaglandin formation and microbleeding in normal and aspirin treated man. | 1986 | Gut | pmid:3492413 |
| Schneidkraut MJ et al. | Regional release of cyclooxygenase products after radiation exposure of the rat. | 1986 | J. Appl. Physiol. | pmid:3096935 |
| Knapp HR et al. | In vivo indexes of platelet and vascular function during fish-oil administration in patients with atherosclerosis. | 1986 | N. Engl. J. Med. | pmid:3007982 |
| Ishibashi M et al. | The diethylhydrogensilyl-cyclic diethylsilylene derivative in the gas chromatography-mass spectrometry of thromboxane B2. | 1986 | Chem. Pharm. Bull. | pmid:3791525 |
| Fagan SC et al. | Prostanoid concentrations in human CSF following acute ischaemic brain infarction. | 1986 | Clin. Exp. Pharmacol. Physiol. | pmid:3791712 |
| Ono N et al. | Pharmacological studies on proglumetacin maleate, a new non-steroidal anti-inflammatory drug (4). Mode of action on anti-inflammatory activity. | 1986 | Jpn. J. Pharmacol. | pmid:3102823 |
| Murdoch WJ | Accumulation of thromboxane B2 within periovulatory ovine follicles: relationship to adhesion of platelets to endothelium. | 1986 | Prostaglandins | pmid:3797693 |
| Vinge E and Björkman S | Compared effects of the two antiinflammatory drugs indoprofen and lonazolac on thromboxane generation and on platelet aggregation, related to plasma concentrations after single oral doses. | 1986 | Acta Pharmacol Toxicol (Copenh) | pmid:3799197 |
| Bellucci S et al. | Thrombocytopenia with thrombocytopathy possibly related to abnormalities of intracellular Ca++ fluxes and followed by the development of leukaemia. | 1986 | Scand J Haematol | pmid:3085207 |
| Kirschenbaum MA | Prostanoids and renal failure. A hypothetical role for prostanoids in progressive renal disease. | 1986 | Contrib Nephrol | pmid:3802815 |
| Poll C et al. | Activation of protein kinase C inhibits sodium fluoride-induced elevation of human platelet cytosolic free calcium and thromboxane B2 generation. | 1986 | Biochem. Biophys. Res. Commun. | pmid:3085668 |
| Müller G et al. | [Thromboxane analyses in patients with chronic inflammatory bowel diseases]. | 1986 | Dtsch Z Verdau Stoffwechselkr | pmid:3803281 |
| Laffi G et al. | Effects of sulindac and ibuprofen in patients with cirrhosis and ascites. An explanation for the renal-sparing effect of sulindac. | 1986 | Gastroenterology | pmid:3079594 |
| Lawson JA et al. | Long-lived enzymatic metabolites of thromboxane B2 in the human circulation. | 1986 | Anal. Biochem. | pmid:3087234 |
| Cerletti C et al. | Biochemical selectivity of oral versus intravenous aspirin in rats. Inhibition by oral aspirin of cyclooxygenase activity in platelets and presystemic but not systemic vessels. | 1986 | J. Clin. Invest. | pmid:3088044 |
| Walenga RW et al. | Time-dependent inhibition of platelet cyclooxygenase by indomethacin is slowly reversible. | 1986 | Prostaglandins | pmid:3088675 |
| Feddersen CO et al. | Acetylcholine induces vasodilation and prostacyclin synthesis in rat lungs. | 1986 | Prostaglandins | pmid:3088679 |
| Hawkey CJ | Synthesis of prostaglandin E2, thromboxane B2 and prostaglandin catabolism in gastritis and gastric ulcer. | 1986 | Gut | pmid:3468053 |
| Schaub RG and Yamashita A | Leukocyte mediated vein injury and thrombosis is reduced by a lipoxygenase inhibitor. | 1986 | Exp. Mol. Pathol. | pmid:3025012 |
| Krishnamurthi S et al. | Synergistic potentiation of 5-hydroxytryptamine secretion by platelet agonists and phorbol myristate acetate despite inhibition of agonist-induced arachidonate/thromboxane and beta-thromboglobulin release and Ca2+ mobilization by phorbol myristate acetate. | 1986 | Biochem. J. | pmid:2948494 |
| Yui Y et al. | Selective thromboxane A2 synthetase inhibition in vasospastic angina pectoris. | 1986 | J. Am. Coll. Cardiol. | pmid:3941213 |
| Eynard AR et al. | Aspirin inhibits platelet 12-hydroxy-eicosatetraenoic acid formation. | 1986 | J. Lab. Clin. Med. | pmid:3941295 |
| Kobinia GS et al. | Effect of experimental cardiopulmonary bypass on systemic and transcardiac thromboxane B2 levels. | 1986 | J. Thorac. Cardiovasc. Surg. | pmid:3754915 |
| DiMinno G et al. | Trial of repeated low-dose aspirin in diabetic angiopathy. | 1986 | Blood | pmid:3092890 |
| Sandler H et al. | Studies on the role of thromboxane in thrombin-induced pulmonary insufficiency in the rat. | 1986 | Thromb. Res. | pmid:3754987 |
| Efimov VV and LadnyÄ AI | [Status of the prostacyclin and thromboxane system, lipid metabolism and lipid peroxidation processes in patients with coronary atherosclerosis]. | 1986 | Vrach Delo | pmid:3754994 |
| Matsumura H et al. | [Antagonism of collagen-induced ECG changes in rats by a thromboxane synthetase inhibitor, CV-4151]. | 1986 | Nippon Yakurigaku Zasshi | pmid:3755113 |
| Fukushima M and Kobayashi T | Effects of thromboxane synthase inhibition on air emboli lung injury in sheep. | 1986 | J. Appl. Physiol. | pmid:3755131 |
| Fleming WH et al. | Serum concentrations of prostacyclin and thromboxane in children before, during, and after cardiopulmonary bypass. | 1986 | J. Thorac. Cardiovasc. Surg. | pmid:3755198 |
| Westlund P et al. | Identification of 11-dehydro-TXB2 as a suitable parameter for monitoring thromboxane production in the human. | 1986 | Prostaglandins | pmid:3755250 |
| Ekblad U | The effect of oxytocin and betamimetic stimulation on prostaglandin release in perfused human fetal placenta. | 1986 | Eur. J. Obstet. Gynecol. Reprod. Biol. | pmid:3469120 |
| Granström E | Methodology in prostaglandin and thromboxane assay. | 1986 | Prog. Lipid Res. | pmid:3321087 |
| Gairola CG and Tai HH | Cigarette smoke-induced alterations in the release of arachidonate metabolites by pulmonary alveolar macrophage from selenium-fed and selenium-deficient rats. | 1986 | Biochem. Pharmacol. | pmid:3015150 |
| Neri Serneri GG et al. | Enhanced peripheral vasoconstrictor response and increased thromboxane A2 synthesis after the cold pressor test in patients with angina at rest. | 1986 | Circulation | pmid:3948351 |
| Dupont J et al. | Eicosanoid synthesis in Alagille syndrome. | 1986 | N. Engl. J. Med. | pmid:3951499 |
| Yanni JM and Smith WL | Intravenous SRS-induced increases in tracheal mucous gel layer thickness: evidence for thromboxane involvement. | 1986 | Prostaglandins | pmid:3952339 |
| Manny J et al. | Pulmonary and systemic consequences of localized acid aspiration. | 1986 | Surg Gynecol Obstet | pmid:3952619 |
| O'Connor KM et al. | Effect of thromboxane synthetase inhibition on vulnerability to ventricular arrhythmia following coronary occlusion. | 1986 | Am. Heart J. | pmid:3953390 |
| Del Principe D et al. | Vitamin E consumption by human blood platelets activated by latex particles. | 1986 | Am. J. Hematol. | pmid:3953557 |
| Sinzinger H et al. | Platelet half-life, plasma thromboxane B2 and circulating endothelial-cells in peripheral vascular disease. | 1986 | Angiology | pmid:3954150 |
| Tomasi V et al. | Are the vascular complications of diabetes mellitus preceded by an altered thromboxane/prostacyclin plasmatic ratio? | 1986 | Med. Hypotheses | pmid:3007948 |
| Noonan TC and Malik AB | Pulmonary vascular response to leukotriene D4 in unanesthetized sheep: role of thromboxane. | 1986 | J. Appl. Physiol. | pmid:3957828 |
| Hatmi M et al. | Modulation by cyclic AMP of arachidonic acid-induced platelet desensitization. | 1986 | Eur. J. Pharmacol. | pmid:3028837 |
| Kumlin M and Granström E | Radioimmunoassay for 11-dehydro-TXB2: a method for monitoring thromboxane production in vivo. | 1986 | Prostaglandins | pmid:3823488 |
| di Minno G et al. | The binding of fibrinogen to platelets in diabetes mellitus. | 1986 | Wien. Klin. Wochenschr. | pmid:3010580 |
| Foegh ML et al. | Coronary artery thrombosis and elevated urine immunoreactive thromboxane B2. | 1986 | Prostaglandins | pmid:3823490 |
| Kiviniemi H and Rämo OJ | The behaviour of prostanoids during the course of acute experimental pancreatitis in rats. | 1986 | Res Exp Med (Berl) | pmid:3823620 |
| Cizmeci G | In vivo effects of defibrotide on platelet c-AMP and blood prostanoid levels. | 1986 | Haemostasis | pmid:3011617 |
| Rouse IL et al. | Nutrient intake, blood pressure, serum and urinary prostaglandins and serum thromboxane B2 in a controlled trial with a lacto-ovo-vegetarian diet. | 1986 | J. Hypertens. | pmid:3011891 |
| Podjarny E et al. | Effect of angiotensin II on prostanoid synthesis in isolated rat glomeruli. | 1986 | Clin. Sci. | pmid:3457671 |
| Laffi G et al. | Altered renal and platelet arachidonic acid metabolism in cirrhosis. | 1986 | Gastroenterology | pmid:3079716 |
| Prosdocimi M et al. | Action of AD6 (8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxycarbonylmet hox y coumarin) on human platelets in vitro. | 1986 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:3012375 |
| Riess H et al. | Thromboxane receptor blockade versus cyclooxigenase inhibition: antiplatelet effects in patients. | 1986 | Thromb. Res. | pmid:3012819 |
| Altman R et al. | Synergistic actions of PAF-acether and sodium arachidonate in human platelet aggregation. 1. Studies in normal human platelet rich plasma. | 1986 | Thromb. Res. | pmid:3014677 |
| Gyllenhammar H et al. | Essential fatty acid deficiency in rats: effects on arachidonate metabolism, generation of cyclooxygenase products and functional responses in neutrophils. | 1986 | Immunol. Lett. | pmid:3095230 |
| Sokolov EI et al. | [Disorders in the status of the vessel-thrombocyte and plasma links of the hemostatic system in the pathogenesis of disseminated intravascular coagulation in ischemic heart disease]. | 1986 | Kardiologiia | pmid:3784270 |
| Friesinger GC and Robertson RM | Vasospastic angina: a continuing search for mechanism(s). | 1986 | J. Am. Coll. Cardiol. | pmid:3510238 |
| Boukili MA et al. | Pharmacological modulation of the effects of N-formyl-L-methionyl-L-leucyl-L-phenylalanine in guinea-pigs: involvement of the arachidonic acid cascade. | 1986 | Br. J. Pharmacol. | pmid:3096407 |
| Singer P et al. | Long-term effect of mackerel diet on blood pressure, serum lipids and thromboxane formation in patients with mild essential hypertension. | 1986 | Atherosclerosis | pmid:3026412 |
| Srivastava KC | Isolation and effects of some ginger components of platelet aggregation and eicosanoid biosynthesis. | 1986 | Prostaglandins Leukot Med | pmid:3103137 |
| Bucchi F et al. | Effects of 1 gram oral or intravenous aspirin on urinary excretion of thromboxane B2 and 6-keto-PGF1 alpha in healthy subjects. | 1986 | Prostaglandins | pmid:3103169 |
| Bales CW et al. | The effect of zinc deficiency and food restriction on prostaglandin E2 and thromboxane B2 in saliva and plasma of rats. | 1986 | Prostaglandins | pmid:3460117 |
| Kintner DB et al. | Cerebral vascular resistance following platelet and leukocyte removal from perfusate. | 1986 | J. Cereb. Blood Flow Metab. | pmid:3944216 |
| Patrono C et al. | Estimated rate of thromboxane secretion into the circulation of normal humans. | 1986 | J. Clin. Invest. | pmid:3944270 |
| Butler KD et al. | The effects of modulation of prostanoid metabolism on the thoracic platelet accumulation induced by intravenous administration of collagen in the guinea-pig. | 1986 | Thromb. Haemost. | pmid:3105104 |