Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Zahavi M and Zahavi J | Concomitant in vitro platelet hypofunction and increased thromboxane B2 (TXB2) generation and enhanced in vivo platelet activation. A distinct syndrome in thrombosis? | 1997 | Eur. J. Haematol. | pmid:9338626 |
Supanz S et al. | Effects of the novel thromboxane (TXA2) receptor antagonist linotroban on inulin and para-aminohippuric acid clearances in the conscious male and female rat. | 1997 | Arzneimittelforschung | pmid:9342416 |
Neupert W et al. | Effects of ibuprofen enantiomers and its coenzyme A thioesters on human prostaglandin endoperoxide synthases. | 1997 | Br. J. Pharmacol. | pmid:9351505 |
Lahoz C et al. | Effects of dietary fat saturation on eicosanoid production, platelet aggregation and blood pressure. | 1997 | Eur. J. Clin. Invest. | pmid:9352251 |
Baskett A et al. | Effect of pentoxifylline, flunixin meglumine, and their combination on a model of endotoxemia in horses. | 1997 | Am. J. Vet. Res. | pmid:9361895 |
Barton MH et al. | Effects of pentoxifylline infusion on response of horses to in vivo challenge exposure with endotoxin. | 1997 | Am. J. Vet. Res. | pmid:9361896 |
Chen L et al. | Cyclooxygenase inhibition decreases nitric oxide synthase activity in human platelets. | 1997 | Am. J. Physiol. | pmid:9362253 |
Bar J et al. | The regulation of platelet aggregation in vitro by interleukin-1beta and tumor necrosis factor-alpha: changes in pregnancy and in pre-eclampsia. | 1997 | Thromb. Haemost. | pmid:9364994 |
Walker JS et al. | Nonsteroidal antiinflammatory drugs in rheumatoid arthritis and osteoarthritis: support for the concept of "responders" and "nonresponders". | 1997 | Arthritis Rheum. | pmid:9365082 |
Riendeau D et al. | Comparison of the cyclooxygenase-1 inhibitory properties of nonsteroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 inhibitors, using sensitive microsomal and platelet assays. | 1997 | Can. J. Physiol. Pharmacol. | pmid:9365818 |
John H and Schlegel W | Reversed-phase high-performance liquid chromatographic method for the determination of the 11-hydroxythromboxane B2 anomers equilibrium. | 1997 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:9367188 |
Capponi A et al. | Indomethacin modifies the fetal hemodynamic response induced by percutaneous umbilical blood sampling. | 1997 | Am. J. Obstet. Gynecol. | pmid:9369815 |
Siler-Khodr TM et al. | The effect of dexamethasone on CRH and prostanoid production from human term placenta. | 1997 | Prostaglandins | pmid:9373879 |
Farker K et al. | Measurements of urinary prostaglandins in young ovulatory women during the menstrual cycle and in postmenopausal women. | 1997 | Prostaglandins | pmid:9373880 |
Savla U et al. | Cyclic stretch of airway epithelium inhibits prostanoid synthesis. | 1997 | Am. J. Physiol. | pmid:9374729 |
Kobayashi T et al. | Changes in platelet calcium concentration by thromboxane A2 stimulation in patients with nephrotic syndrome of childhood. | 1997 | Nephron | pmid:9375825 |
Nygaard OP et al. | The inflammatory properties of contained and noncontained lumbar disc herniation. | 1997 | Spine | pmid:9383853 |
Xiao X et al. | Effect of captopril on renal hemodynamics and renal prostaglandins in early type II diabetic patients with normo-or microalbuminuria. | 1996 | Chin. Med. Sci. J. | pmid:9387403 |
Sang Y et al. | [Effects of tangshenkang capsule on diabetic nephropathy]. | 1996 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:9387731 |
Han JA and Hu WY | [Progress in the study on protective effect of saponins Panax notoginseng on ischemic brain damage]. | 1996 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:9387754 |