Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Mitchell MD et al. | Thromboxane B-2 in the plasma and amniotic fluid of late pregnant and periparturient sheep. | 1979 | J. Reprod. Fertil. | pmid:423152 |
Tobelem G et al. | Further studies on a specific platelet antibody found in Bernard-Soulier syndrome and its effects on normal platelet function. | 1979 | Br. J. Haematol. | pmid:427045 |
Friedman LS et al. | Cardiovascular and pulmonary effects of thromboxane B2 in the dog. | 1979 | Circ. Res. | pmid:428069 |
Ciabattoni G et al. | Characterization of furosemide-induced activation of the renal prostaglandin system. | 1979 | Eur. J. Pharmacol. | pmid:393525 |
Svensson J | Structure and quantitative determination of the major urinary metabolite of thromboxane B2 in the guinea pig. | 1979 | Prostaglandins | pmid:472333 |
Russell NH et al. | Thrombocytopathy in preleukaemia: association with a defect of thromboxane A2 activity. | 1979 | Br. J. Haematol. | pmid:570847 |
Anhut H et al. | Prostaglandin D2 is the prevailing prostaglandin in the acute inflammatory exudate of urate arthritis in the chicken. | 1979 | Br. J. Pharmacol. | pmid:570865 |
Lewy RI et al. | Detection of thromboxane B2 in peripheral blood of patients with Prinzmetal's angina. | 1979 | Prostaglandins Med | pmid:575861 |
Lewy RI et al. | Intravenous heparin initiates in-vivo synthesis and release of thromboxane in angina pectoris. | 1979 | Lancet | pmid:87990 |
Güllner HG et al. | Prostacyclin overproduction in Bartter's syndrome. | 1979 | Lancet | pmid:90861 |
Davis TM et al. | Prostacyclin and thromboxane metabolites in diabetes. | 1979 | Lancet | pmid:90875 |
Best L et al. | Effect of glucose on platelet thromboxane biosynthesis. | 1979 | Lancet | pmid:90876 |
Jarabak J and Fried J | Comparison of substrate specificities of the human placental NAD- and NADP-linked 15-hydroxyprostaglandin dehydrogenases. | 1979 | Prostaglandins | pmid:42948 |
Miura Y and Fukui N | Prostaglandins as possible triggers for liver regeneration after partial hepatectomy. A review. | 1979 | Cell Mol Biol Incl Cyto Enzymol | pmid:44483 |
Spagnuolo C et al. | PGF2 alpha, thromboxane B2 and HETE levels in gerbil brain cortex after ligation of common carotid arteries and decapitation. | 1979 | Prostaglandins | pmid:230539 |
Jonsson CE et al. | Efflux of cyclic AMP, prostaglandin E2 and F2 alpha and thromboxane B2 in leg lymph of rabbits after scalding injury. | 1979 | Acta Physiol. Scand. | pmid:232367 |
Karmazyn M and Dhalla NS | Thromboxane B2: a cardiodepressant of isolated rat hearts and inhibitor of sarcolemma Na+ - K+ stimulated ATPase activity. | 1979 | Prostaglandins Med | pmid:233217 |
Hassid A et al. | Prostaglandin synthesis in isolated rat kidney glomeruli. | 1979 | Proc. Natl. Acad. Sci. U.S.A. | pmid:286300 |
Le Breton GC et al. | 13-Azaprostanoic acid: a specific antagonist of the human blood platelet thromboxane/endoperoxide receptor. | 1979 | Proc. Natl. Acad. Sci. U.S.A. | pmid:291066 |
Chignard M et al. | Arachidonate-mediated bronchoconstriction and platelet activation are inhibited by microgram doses of compound L8027 which are not selective for thromboxane synthetase. | 1979 | Agents Actions Suppl. | pmid:291306 |