Thromboxane b2

Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.

Cross Reference

Introduction

To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Thromboxane b2?

Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Thromboxane b2

MeSH term MeSH ID Detail
Disseminated Intravascular Coagulation D004211 7 associated lipids
Uveitis D014605 14 associated lipids
Byssinosis D002095 11 associated lipids
Enteritis D004751 8 associated lipids
Pneumonia, Aspiration D011015 3 associated lipids
Periapical Periodontitis D010485 6 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Arthus Reaction D001183 8 associated lipids
Angina Pectoris D000787 27 associated lipids
Angina, Unstable D000789 14 associated lipids
Vascular Diseases D014652 16 associated lipids
Pregnancy Complications, Hematologic D011250 11 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Ascites D001201 25 associated lipids
Albuminuria D000419 18 associated lipids
Anemia D000740 21 associated lipids
Chediak-Higashi Syndrome D002609 4 associated lipids
Heart Valve Diseases D006349 4 associated lipids
Infant, Premature, Diseases D007235 7 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Coronary Vasospasm D003329 9 associated lipids
Scleroderma, Systemic D012595 16 associated lipids
Keratitis D007634 7 associated lipids
Mastitis, Bovine D008414 8 associated lipids
Celiac Disease D002446 16 associated lipids
Rhinitis, Allergic, Seasonal D006255 7 associated lipids
Placenta Diseases D010922 5 associated lipids
Salmonella Infections, Animal D012481 9 associated lipids
Raynaud Disease D011928 7 associated lipids
Nephritis D009393 19 associated lipids
Bartter Syndrome D001477 5 associated lipids
Respiration Disorders D012120 5 associated lipids
Renal Artery Obstruction D012078 8 associated lipids
Hypolipoproteinemias D007009 9 associated lipids
Carotid Stenosis D016893 15 associated lipids
Influenza, Human D007251 11 associated lipids
Bronchopneumonia D001996 7 associated lipids
Facial Pain D005157 5 associated lipids
Abortion, Habitual D000026 5 associated lipids
Eye Burns D005126 13 associated lipids
Retinal Detachment D012163 10 associated lipids
Cleft Palate D002972 9 associated lipids
Choline Deficiency D002796 16 associated lipids
Leiomyosarcoma D007890 4 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Atrial Fibrillation D001281 16 associated lipids
Coronary Thrombosis D003328 7 associated lipids
Glomerulonephritis, Membranous D015433 6 associated lipids
Per page 10 20 50 100 | Total 293

PubChem Associated disorders and diseases

What pathways are associated with Thromboxane b2

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Thromboxane b2?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Thromboxane b2?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

What genes are associated with Thromboxane b2?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Thromboxane b2?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Thromboxane b2

Download all related citations
Per page 10 20 50 100 | Total 6367
Authors Title Published Journal PubMed Link
Mäkilä UM et al. Relation between umbilical prostacyclin production and blood-flow in the fetus. 1983 Lancet pmid:6132081
Thorngren M et al. Thromboxane A2 in skin-bleeding-time blood and in clotted venous blood before and after administration of acetylsalicylic acid. 1983 Lancet pmid:6133107
Drake TS et al. Peritoneal fluid prostanoids in unexplained infertility. 1983 Am. J. Obstet. Gynecol. pmid:6614085
Stenson WF and Lobos E Inhibition of platelet thromboxane synthetase by sulfasalazine. 1983 Biochem. Pharmacol. pmid:6135423
Chang J et al. Effects of thiazinamium chloride, promethazine and chlorpromazine on thromboxane B2 synthesis, phagocytosis and respiratory burst by rat alveolar macrophages. 1983 Biochem. Pharmacol. pmid:6138040
Deckmyn H et al. Manipulation of the local thromboxane and prostacyclin balance in vivo by the antithrombotic compounds dazoxiben, acetylsalicylic acid and nafazatrom. 1983 Biochem. Pharmacol. pmid:6578796
Saldeen P et al. Increased synthesis of thromboxane B2 and 6-keto-PGF1 alpha in hand veins from patients with deep venous thrombosis. 1983 Thromb. Res. pmid:6658723
Goetzl EJ et al. Enhancement of human neutrophil adherence by synthetic leukotriene constituents of the slow-reacting substance of anaphylaxis. 1983 Immunology pmid:6193056
McManus LM et al. Thromboxane B2 (TxB2) release following acetyl glyceryl ether phosphorylcholine (AGEPC) infusion in the rabbit. 1983 Immunopharmacology pmid:6832960
Martin JL et al. Effect of atrial pacing on intracoronary thromboxane production in coronary artery disease. 1983 J. Am. Coll. Cardiol. pmid:6833660
Ferraris VA and Swanson E Aspirin usage and perioperative blood loss in patients undergoing unexpected operations. 1983 Surg Gynecol Obstet pmid:6836459
Margotat A et al. A rapid and simple assay for the study of thromboxane B2 synthesis by intact human platelets. 1983 J Pharmacol Methods pmid:6843139
Rotmensch HH et al. Plasma platelet products and exercise-induced myocardial ischemia. 1983 J. Lab. Clin. Med. pmid:6854135
Hamelin SS and Chan AC Modulation of platelet thromboxane and malonaldehyde by dietary vitamin E and linoleate. 1983 Lipids pmid:6855486
De Clerck F et al. Platelet activation by endogenous 5-hydroxytryptamine and histamine released by mast cell degranulation with compound 48/80 in the rat. 1983 Agents Actions pmid:6858790
Preston FE Aspirin, prostaglandins, and peripheral gangrene. 1983 Am. J. Med. pmid:6859070
Palmer RM and Salmon JA Release of leukotriene B4 from human neutrophils and its relationship to degranulation induced by N-formyl-methionyl-leucyl-phenylalanine, serum-treated zymosan and the ionophore A23187. 1983 Immunology pmid:6309653
Winter M et al. Synthesis of thromboxane B2 in uraemia and the effects of dialysis. 1983 Thromb. Res. pmid:6868024
Menys VC and Davies JA Inhibitory effects of ZK 36374, a stable prostacyclin analogue, on adhesion of rabbit platelets to damaged aorta and serotonin release by adherent platelets. 1983 Clin. Sci. pmid:6190604
Hartung HP and Toyka KV Activation of macrophages by substance P: induction of oxidative burst and thromboxane release. 1983 Eur. J. Pharmacol. pmid:6191998
Tanganelli I et al. [Thromboxane, beta-thromboglobulin and the degree of blood sugar control in type 1 diabetes mellitus]. 1983 Boll. Soc. Ital. Biol. Sper. pmid:6194801
Capodicasa G et al. Platelet thromboxane formation and BTG levels after intensive charcoal HP in uremics or regular hemodialytic treatment (RHT). 1983 Int J Artif Organs pmid:6195116
Ditter H et al. Effects of prostacyclin during cardiopulmonary bypass in men on plasma levels of beta-thromboglobulin, platelet factor 4, thromboxane B2, 6-keto-prostaglandin F1 alpha and heparin. 1983 Thromb. Res. pmid:6197766
Lismonde M et al. [The presence of 6-oxo-PGF1alpha and thromboxane B2 in peritoneal exudates released by iota-carrageenan in the rat]. 1983 Arch. Int. Physiol. Biochim. pmid:6198994
Tolman EL and Fuller BL Inhibition of thromboxane synthesis in guinea pig lung and human platelets by clotrimazole and other imidazole antifungals. 1983 Biochem. Pharmacol. pmid:6316985
Wientroub S et al. Changes in tissue concentration of prostaglandins during endochondral bone differentiation. 1983 Biochem. Biophys. Res. Commun. pmid:6582850
Salmon JA et al. The effects of BW755C and other anti-inflammatory drugs on eicosanoid concentrations and leukocyte accumulation in experimentally-induced acute inflammation. 1983 J. Pharm. Pharmacol. pmid:6141244
Stimler NP and O'Flaherty JT Spasmogenic properties of platelet-activating factor: evidence for a direct mechanism in the contractile response of pulmonary tissues. 1983 Am. J. Pathol. pmid:6624879
Stratta P et al. Warning: platelet factor 4, beta-thromboglobulin and thromboxane in donor's plasma units. 1983 Thromb. Haemost. pmid:6189235
McDaniel HG et al. Platelet function abnormalities in response to arachidonic acid in the acute phase of myocardial infarction. 1983 Am. J. Cardiol. pmid:6416046
de Kergommeaux BD et al. Effects of ASA on thromboxane and prostacyclin synthesis by rabbit aorta and pulmonary artery. 1983 Prostaglandins Leukot Med pmid:6410417
Boughton-Smith NK et al. Biosynthesis of lipoxygenase and cyclo-oxygenase products from [14C]-arachidonic acid by human colonic mucosa. 1983 Gut pmid:6416934
Ylikorkala O Prostacyclin and thromboxane during human pregnancy. 1983 Acta Obstet Gynecol Scand Suppl pmid:6344543
Qvist R and Larkins RG Diminished production of thromboxane B2 and prostaglandin E by stimulated polymorphonuclear leukocytes from insulin-treated diabetic subjects. 1983 Diabetes pmid:6345241
Newman JH et al. Effects of 100% oxygen on lung vascular function in awake sheep. 1983 J Appl Physiol Respir Environ Exerc Physiol pmid:6345493
Eldor A et al. Effects of dipyrone on prostaglandin production by human platelets and cultured bovine aortic endothelial cells. 1983 Thromb. Haemost. pmid:6346571
Menys VC and Davies JA Selective inhibition of thromboxane synthetase with dazoxiben - basis of its inhibitory effect on platelet adhesion. 1983 Thromb. Haemost. pmid:6346575
Reeves WC et al. The release of thromboxane A2 and prostacyclin following experimental acute pulmonary embolism. 1983 Prostaglandins Leukot Med pmid:6348800
Aznavoorian SA et al. Prostacyclin inhibits 5-hydroxytryptamine release but stimulates thromboxane synthesis during cardiopulmonary bypass. 1983 Prostaglandins pmid:6348886
Buchanan MR et al. The sex-related differences in aspirin pharmacokinetics in rabbits and man and its relationship to antiplatelet effects. 1983 Thromb. Res. pmid:6221436
Kaar ML et al. Prostacyclin and thromboxane in diabetic children. 1983 Prostaglandins Leukot Med pmid:6351104
Yamamoto S et al. Enzyme immunoassay of thromboxane B2 and 6-keto-prostaglandin F1 alpha as a substitute for radioimmunoassay. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221523
Fischer S et al. The influence of selective thromboxane synthetase inhibition with a novel imidazole derivative, UK-38,485, on prostanoid formation in man. 1983 Circulation pmid:6352080
Weerasekera DA et al. Chemiluminescence immunoassay of thromboxane B2. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221524
Davi' G et al. Platelet activation after adrenergic stimulation in hypertensive patients: effects of acebutolol. 1983 Eur. Heart J. pmid:6352266
Ito T et al. Effects of a selective inhibitor of thromboxane synthetase (OKY-1581) in humans. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221531
FitzGerald GA et al. Aspirin inhibits endogenous prostacyclin and thromboxane biosynthesis in man. 1983 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:6221534
FitzGerald GA et al. Endogenous prostacyclin biosynthesis and platelet function during selective inhibition of thromboxane synthase in man. 1983 J. Clin. Invest. pmid:6355181
Jouve R et al. [Plasma thromboxane B2 and capacity of the aorta to produce prostacyclin in arteriopathies of the lower extremities]. 1983 J Mal Vasc pmid:6355348
Mehta J et al. Stimulation of vessel wall prostacyclin by selective thromboxane synthetase inhibitor OKY 1581. 1983 Prostaglandins Leukot Med pmid:6356153
Henriksen RA and Brotherton AF Evidence that activation of platelets and endothelium by thrombin involves distinct sites of interaction. Studies with the dysthrombin, Thrombin Quick I. 1983 J. Biol. Chem. pmid:6358210
Kaliman J et al. [Venous prostacycline synthesis and plasma thromboxane B2 after low-dose aspirin]. 1983 Wien. Klin. Wochenschr. pmid:6359724
Kiff PS et al. Haemodynamic and metabolic effects of dazoxiben at rest and during atrial pacing. 1983 Br J Clin Pharmacol pmid:6681708
Hutton I et al. Effects of dazoxiben on transcardiac thromboxane levels and haemodynamics in coronary heart disease. 1983 Br J Clin Pharmacol pmid:6681709
Feddersen CO et al. Leukotriene E4 causes pulmonary vasoconstriction, not inhibited by meclofenamate. 1983 Prostaglandins pmid:6098932
Zijlstra FJ et al. Thrombotic thrombocytopenic purpura and plasma thromboxane B2 levels. 1983 Thromb. Res. pmid:6684333
Lianos EA et al. Glomerular prostaglandin and thromboxane synthesis in rat nephrotoxic serum nephritis. Effects on renal hemodynamics. 1983 J. Clin. Invest. pmid:6685136
Wynalda MA et al. Sodium 5-(3'-pyridinylmethyl)benzofuran-2-carboxylate (U-63557A), a new, selective thromboxane synthase inhibitor: intravenous and oral pharmacokinetics in dogs and correlations with ex situ thromboxane B2 production. 1983 Prostaglandins pmid:6685888
McDonald JW et al. Thromboxane synthesis by sources other than platelets in association with complement-induced pulmonary leukostasis and pulmonary hypertension in sheep. 1983 Circ. Res. pmid:6687354
Randall MJ and Wilding RI Acute arterial thrombosis in rabbits: reduced platelet accumulation after treatment with dazoxiben hydrochloride (UK 37,248-01). 1983 Br J Clin Pharmacol pmid:6687429
Bruckner G et al. Dietary trilinoelaidate: effects on hematological parameters, serum eicosanoids and tissue fatty acid composition in rats. 1983 J. Nutr. pmid:6687476
Bessin P et al. Acute circulatory collapse caused by platelet-activating factor (PAF-acether) in dogs. 1983 Eur. J. Pharmacol. pmid:6687572
Ingerman-Wojenski CM et al. Early morphological changes in the endothelium of a peripheral artery of rabbits fed an atherogenic diet. 1983 Exp. Mol. Pathol. pmid:6687574
Schumacher WA and Lucchesi BR Effect of the thromboxane synthetase inhibitor UK-37,248 (dazoxiben) upon platelet aggregation, coronary artery thrombosis and vascular reactivity. 1983 J. Pharmacol. Exp. Ther. pmid:6418881
Morita I et al. Stimulation of eicosapentaenoic acid metabolism in washed human platelets by 12-hydroperoxyeicosatetraenoic acid. 1983 J. Biol. Chem. pmid:6309794
Hartung HP and Toyka KV Tuftsin stimulates the release of oxygen radicals and thromboxane from macrophages. 1983 Immunol. Lett. pmid:6687720
Westwick J et al. Platelet activation during steady state sickle cell disease. 1983 J Med pmid:6224876
Kurata M [Relation between mouse peritoneal macrophage functions and prostaglandins]. 1983 Rinsho Byori pmid:6689184
Maguire ED and Wallis RB In vivo redirection of prostaglandin endoperoxides into 6-keto PGF1 alpha formation by thromboxane synthetase inhibitors in the rat. 1983 Thromb. Res. pmid:6689221
Zijlstra FJ and Vincent JE Comparison of the determination of thromboxane A2 by bioassay on the rabbit mesenteric artery and in the form of TxB2 by radioimmunoassay. 1983 J Pharmacol Methods pmid:6632924
Bryant RW and Hwang DH Development of a radioimmunoassay for 15-HETE and its application to 15-HETE production by reticulocytes. 1983 Prostaglandins pmid:6419285
Wilson L Effects of estradiol and progesterone on uterine prostaglandin levels in the pregnant rat. 1983 Prostaglandins pmid:6635211
Sanders TA and Hochland MC A comparison of the influence on plasma lipids and platelet function of supplements of omega 3 and omega 6 polyunsaturated fatty acids. 1983 Br. J. Nutr. pmid:6639916
Mehta JL Prostaglandins: regulatory role in cardiovascular system and implications in ischemic heart disease. 1983 Int. J. Cardiol. pmid:6642760
Mathieson MA et al. Ischemia of the limb stimulates thromboxane production and myocardial depression. 1983 Surg Gynecol Obstet pmid:6648769
Barrett PA and Butler KD Shortening of platelet survival by induced hypercholesterolaemia in rabbits and its prolongation by anagrelide. 1983 Thromb. Haemost. pmid:6648889
Robinson C and Hoult JR Thromboxane A2 analogues inhibit the metabolism of thromboxane B2 in perfused guinea-pig lung. 1983 Biochim. Biophys. Acta pmid:6652102
Higgs GA et al. The source of thromboxane and prostaglandins in experimental inflammation. 1983 Br. J. Pharmacol. pmid:6652359
Anton RF et al. In vivo regional levels of PGE and thromboxane in mouse brain: effect of decapitation, focused microwave fixation, and indomethacin. 1983 Prostaglandins pmid:6658001
Mahoney D et al. Influence of dietary polyunsaturated fatty acids on renal & aortic prostaglandin synthesis in 1 kidney 1 clip Goldblatt hypertensive rats. 1983 Prostaglandins pmid:6658002
Martin JF et al. The biological significance of platelet volume: its relationship to bleeding time, platelet thromboxane B2 production and megakaryocyte nuclear DNA concentration. 1983 Thromb. Res. pmid:6658722
Cohen RA et al. 5-Hydroxytryptamine can mediate endothelium-dependent relaxation of coronary arteries. 1983 Am. J. Physiol. pmid:6660308
Socini A et al. Fish oil administration as a supplement to a corn oil containing diet affects arterial prostacyclin production more than platelet thromboxane formation in the rat. 1983 Prostaglandins pmid:6310702
Karmali RA et al. Prostaglandins in breast cancer: relationship to disease stage and hormone status. 1983 Br. J. Cancer pmid:6416285
Gethmann U et al. Effect of catecholestrogens on prostaglandin release by rat pituitaries superfused in vitro. 1983 Arch. Gynecol. pmid:6320749
Ouwendijk RJ et al. Raised plasma thromboxane B2 levels in alcoholic liver disease. 1983 Prostaglandins Leukot Med pmid:6573682
Hornych A et al. Thromboxane B2 in borderline and essential hypertensive patients. 1983 Prostaglandins Leukot Med pmid:6573683
Flynn JT et al. Effects of anesthesia and surgery on prostanoid concentrations in plasma and pulmonary lymph. 1983 Prostaglandins Leukot Med pmid:6573688
Patel K and Bakhle YS Thromboxane B2 (TxB2) metabolism in rat isolated lung and its inhibition by drugs. 1983 Prostaglandins Leukot Med pmid:6573689
Davì G et al. Plasmatic TXB2 and 6-keto-PGF1 alpha levels during charcoal hemoperfusion in chronic renal failure patients. 1983 Prostaglandins Leukot Med pmid:6573692
Lieb J et al. Elevated levels of prostaglandin E2 and thromboxane B2 in depression. 1983 Prostaglandins Leukot Med pmid:6574523
Coceani F et al. Prostaglandin E2 and thromboxane B2 in cerebrospinal fluid of afebrile and febrile cat. 1983 Am. J. Physiol. pmid:6574712
Viinikka L et al. Effect of prolonged treatment with acetylsalicylic acid and dipyridamole on platelet thromboxane A2 production in atherosclerotic subjects. 1983 Prostaglandins Leukot Med pmid:6576385
Fukumoto S and Tanaka K Protective effects of thromboxane A2 synthetase inhibitors on endotoxin shock. 1983 Prostaglandins Leukot Med pmid:6576388
Kinney EL et al. Mechanism of action of amrinone: role of thromboxane synthetase inhibition. 1983 Prostaglandins Leukot Med pmid:6576389
Hawkey CJ et al. Imbalance of prostacyclin and thromboxane synthesis in Crohn's disease. 1983 Gut pmid:6578172
Zijlstra FJ et al. Separation of the two components of the contractile activity of leukotriene C4 on the guinea pig lung parenchymal strip. 1983 Prostaglandins Leukot Med pmid:6578519
Mahoney DP et al. Radioimmunoassay of prostaglandins and thromboxane B2 in extracted and unextracted urine and serum using an iodinated ligand. 1983 Prostaglandins Leukot Med pmid:6579570
Güllner HG et al. Renal thromboxane excretion in Brattleboro rats with hereditary hypothalamic diabetes insipidus. Effect of vasopressin treatment. 1983 Prostaglandins Leukot Med pmid:6580653
Carr BR et al. Prostaglandin secretion by the neocortex and fetal zones of the human fetal adrenal gland. 1983 J. Clin. Endocrinol. Metab. pmid:6313732