Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele.
To understand associated biological information of Thromboxane b2, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Thromboxane b2 is suspected in endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia, Thrombocytosis, Acute Coronary Syndrome and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Thromboxane b2
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
pmid: | ||||
Michelson AD et al. | The effects of aspirin and hypothermia on platelet function in vivo. | 1999 | Br. J. Haematol. | pmid:10027713 |
Andrieu S et al. | Effects of antiaggregant and antiinflammatory doses of aspirin on coronary hemodynamics and myocardial reactive hyperemia in conscious dogs. | 1999 | J. Cardiovasc. Pharmacol. | pmid:10028935 |
Van de Weerdt ML et al. | Ketoprofen and phenylbutazone attenuation of PAF-induced lung inflammation in calves. | 1999 | Vet. J. | pmid:10030127 |
Carvalho C et al. | Inhibition of airway hyperreactivity, edema, and lung cell infiltration by compound U-83836E in sensitized guinea pigs. | 1998 Jul-Aug | Can. J. Physiol. Pharmacol. | pmid:10030451 |
Kitagawa M et al. | The role of the spleen, especially regarding changes in both thromboxane A2 and the remnant liver dysfunction after extensive hepatectomy. | 1999 | Surg. Today | pmid:10030738 |
Serebruany VL and Gurbel PA | Assessment of platelet activity by measuring platelet-derived substances in plasma from patients with acute myocardial infarction: surprising lessons from the GUSTO-III Platelet Study. | 1999 | Thromb. Res. | pmid:10030832 |
Jokela R et al. | Effect of in vitro stability of dietary fish oil on lipid peroxidation and prostanoids in vivo. | 1998 | Ups. J. Med. Sci. | pmid:10052110 |
van Kooten F et al. | Increased platelet activation in the chronic phase after cerebral ischemia and intracerebral hemorrhage. | 1999 | Stroke | pmid:10066850 |
Langberg H et al. | Metabolism and inflammatory mediators in the peritendinous space measured by microdialysis during intermittent isometric exercise in humans. | 1999 | J. Physiol. (Lond.) | pmid:10066916 |
Mink SN et al. | Effect of bolus epinephrine on systemic hemodynamics in canine anaphylactic shock. | 1998 | Cardiovasc. Res. | pmid:10070496 |
Fukushima C et al. | In vitro responses to antigen stimulation: comparison between human lung parenchyma resected from asthmatic patients and non-asthmatic patients. | 1999 | Ann. Allergy Asthma Immunol. | pmid:10071522 |
Takahashi H et al. | Ureteral obstruction reverses glomerular proliferation in immune complex glomerulonephritis. | 1999 | J. Lab. Clin. Med. | pmid:10072261 |
Shen ZQ et al. | Inhibitory effects of copper-aspirin complex on platelet aggregation. | 1997 | Zhongguo Yao Li Xue Bao | pmid:10072923 |
Zeng S and Guo ZG | Mepyramine inhibits platelet activating factor-induced rabbit platelet aggregation: role of intracellular histamine. | 1997 | Zhongguo Yao Li Xue Bao | pmid:10072970 |
Li W et al. | [Influence of qi-gong on plasma TXB2 and 6-keto-PGF1 alpha in two TCM types of essential hypertension]. | 1997 | Hunan Yi Ke Da Xue Xue Bao | pmid:10072988 |
Yi Z et al. | [Changes and evaluation of indexes on treating ganyanghuafengzheng with cerebral infarction by tianlongxifeng granulae]. | 1997 | Hunan Yi Ke Da Xue Xue Bao | pmid:10073023 |
Pestana M et al. | Kidney graft-infiltrating cells synthesize significantly higher amounts of prostaglandin E2 pre and during acute rejection. | 1999 Feb-Mar | Transplant. Proc. | pmid:10083119 |
van den Dorpel MA et al. | Beneficial effects of conversion from cyclosporine to azathioprine on fibrinolysis in renal transplant recipients. | 1999 Feb-Mar | Transplant. Proc. | pmid:10083130 |
van Genderen PJ et al. | Thromboxane-dependent platelet activation in vivo precedes arterial thrombosis in thrombocythaemia: a rationale for the use of low-dose aspirin as an antithrombotic agent. | 1999 | Br. J. Haematol. | pmid:10086775 |
Hu MK et al. | Synthesis and evaluation of backbone/amide-modified analogs of leualacin. | 1999 | Bioorg. Med. Chem. Lett. | pmid:10098664 |
Takami M and Tsukada W | Effects of DP-1904, a thromboxane synthetase inhibitor, on the antigen-induced airway hyperresponsiveness and infiltration of inflammatory cells in guinea-pigs. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10102387 |
Stenach N et al. | The effects of heparin bound surface modification (Carmeda Bioactive Surface) on human platelet alterations during simulated extracorporeal circulation. | 1992 | J Extra Corpor Technol | pmid:10148074 |
Mitchell MD et al. | Production of thromboxane B2 by the intra-uterine tissues from late pregnant Rhesus monkeys (Macaca mulatta) in vitro. | 1978 | J. Endocrinol. | pmid:101641 |
Mayer AM et al. | Escherichia coli lipopolysaccharide potentiation and inhibition of rat neonatal microglia superoxide anion generation: correlation with prior lactic dehydrogenase, nitric oxide, tumor necrosis factor-alpha, thromboxane B2, and metalloprotease release. | 1999 | Shock | pmid:10188770 |
Kay-Mugford T and Conlon P | Possible inconsistencies in study on cyclooxygenase. | 1999 | Am. J. Vet. Res. | pmid:10188806 |
Yamamoto T et al. | Production of prostanoids and nitric oxide by infarcted heart in situ and the effect of aspirin. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10198239 |
Nelson DM et al. | Hypoxia limits differentiation and up-regulates expression and activity of prostaglandin H synthase 2 in cultured trophoblast from term human placenta. | 1999 | Am. J. Obstet. Gynecol. | pmid:10203658 |
Chakraborti T et al. | Age-dependent change in arachidonic acid metabolic capacity in rat alveolar macrophages. | 1999 | Biochem. Mol. Biol. Int. | pmid:10204087 |
Catella-Lawson F et al. | Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10215647 |
Dirig DM and Yaksh TL | In vitro prostanoid release from spinal cord following peripheral inflammation: effects of substance P, NMDA and capsaicin. | 1999 | Br. J. Pharmacol. | pmid:10217526 |
Sayar K and Melli M | Effect of combination of misoprostol and indomethacin on eicosanoid production in carrageenan-induced air pouch inflammation in rats. | 1999 | Eur. J. Pharmacol. | pmid:10225376 |
Monneret G et al. | Renal effects of cP450 arachidonate metabolites in the Lyon hypertensive rat. | 1999 | Fundam Clin Pharmacol | pmid:10226768 |
Braun-Dullaeus RC et al. | Cyclosporine-induced coronary artery constriction--dissociation between thromboxane release and coronary vasospasm. | 1999 | J. Heart Lung Transplant. | pmid:10226897 |
Takao A et al. | Inhibitory effects of azelastine hydrochloride in alcohol-induced asthma. | 1999 | Ann. Allergy Asthma Immunol. | pmid:10227338 |
Tomoeda H | Effects of leukocyte-depleted warm blood cardioplegia on cardiac and endothelial function. | 1999 | Kurume Med J | pmid:10319611 |
Truitt A et al. | Antiplatelet effects of conjugated linoleic acid isomers. | 1999 | Biochim. Biophys. Acta | pmid:10320806 |
Arons MM et al. | Effects of ibuprofen on the physiology and survival of hypothermic sepsis. Ibuprofen in Sepsis Study Group. | 1999 | Crit. Care Med. | pmid:10321658 |
Tang QZ et al. | [Effect of buyang huanwu decoction on platelet function and fibrinolytic activity of unstable angina pectoris patients]. | 1997 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:10322871 |
Chen SX et al. | [Effects of tetramethylpyrazine on platelet functions of advanced cases of lung carcinoma]. | 1997 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:10322873 |
Chong ZZ and Feng YP | Effects of dl-3-n-butylphthalide on production of TXB2 and 6-keto-PGF1 alpha in rat brain during focal cerebral ischemia and reperfusion. | 1997 | Zhongguo Yao Li Xue Bao | pmid:10322905 |
Hanaoka M et al. | Interferon-alpha elevates pulmonary blood pressure in sheep--the role of thromboxane cascade. | 1999 | Eur. J. Pharmacol. | pmid:10323263 |
Heindl B et al. | The volatile anesthetic sevoflurane mitigates cardiodepressive effects of platelets in reperfused hearts. | 1999 | Basic Res. Cardiol. | pmid:10326658 |
Agnoli GC et al. | Renal function and urinary prostanoid excretions in salt-depleted women: comparative effects of enalapril and indomethacin treatments. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10328327 |
Chahine R et al. | The anti-thromboxane A2 synthetase activity of myocardial tissue and its variation during ischemia and reperfusion in isolated rabbit heart. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10328329 |
Peredo HA and Filinger EJ | Effect of dipyridamole on prostanoid production in rat isolated atria. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10328333 |
Denizot Y et al. | Are lipid mediators implicated in the production of pro- and anti-inflammatory cytokines during cardiopulmonary bypass graft with extracorporeal circulation? | 1999 | Cytokine | pmid:10328869 |
Kanji VK et al. | Vitamin E suppresses cyclosporine A-induced increase in the urinary excretion of arachidonic acid metabolites including F2-isoprostanes in the rat model. | 1999 | Transplant. Proc. | pmid:10331052 |
Salomon P and Halawa B | [Levels of neuropeptide Y and thromboxane B2 in patients with variant angina]. | 1998 | Pol. Arch. Med. Wewn. | pmid:10335040 |
Liguori A et al. | Loop diuretics enhance the secretion of prostacyclin in vitro, in healthy persons, and in patients with chronic heart failure. | 1999 | Eur. J. Clin. Pharmacol. | pmid:10335906 |