12S-HpETE

12s-hpete is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 562 references associated with 12S-HpETE in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for 12S-HpETE

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 12S-HpETE

MeSH term MeSH ID Detail
Diabetic Ketoacidosis D016883 16 associated lipids
Pain D010146 64 associated lipids
Inflammation D007249 119 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Total 5

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 12S-HpETE

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Authors Title Published Journal PubMed Link
Hassan AM Selenium status in patients with aspirin-induced asthma. 2008 Ann. Clin. Biochem. pmid:18753425
Kim SR et al. Interactions between CB(1) receptors and TRPV1 channels mediated by 12-HPETE are cytotoxic to mesencephalic dopaminergic neurons. 2008 Br. J. Pharmacol. pmid:18552868
Wecksler AT et al. Substrate specificity changes for human reticulocyte and epithelial 15-lipoxygenases reveal allosteric product regulation. 2008 Biochemistry pmid:18570379
Okuno T et al. 12(S)-Hydroxyheptadeca-5Z, 8E, 10E-trienoic acid is a natural ligand for leukotriene B4 receptor 2. 2008 J. Exp. Med. pmid:18378794
Sexton A et al. 12-Lipoxygenase-derived eicosanoids protect against myocardial ischemia/reperfusion injury via activation of neuronal TRPV1. 2007 FASEB J. pmid:17470568
Kim DK et al. 12(S)-HPETE induces itch-associated scratchings in mice. 2007 Eur. J. Pharmacol. pmid:17112507
Poeckel D et al. Boswellic acids stimulate arachidonic acid release and 12-lipoxygenase activity in human platelets independent of Ca2+ and differentially interact with platelet-type 12-lipoxygenase. 2006 Mol. Pharmacol. pmid:16788089
Suh YG and Oh U Activation and activators of TRPV1 and their pharmaceutical implication. 2005 Curr. Pharm. Des. pmid:16101449
Coffey MJ et al. Platelet 12-lipoxygenase activation via glycoprotein VI: involvement of multiple signaling pathways in agonist control of H(P)ETE synthesis. 2004 Circ. Res. pmid:15142951
Tanabe M et al. Incorporation of arachidonic and linoleic acid hydroperoxides into cultured human umbilical vein endothelial cells. 2004 Prostaglandins Leukot. Essent. Fatty Acids pmid:15120710